LOCUS       NM_001033466            3227 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus zinc finger and BTB domain containing 2 (Zbtb2),
            transcript variant 1, mRNA.
ACCESSION   NM_001033466 XM_486014 XM_884953 XM_895928 XM_905226 XM_919235
VERSION     NM_001033466.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3227)
  AUTHORS   Medeiros de Araujo JA, Barao S, Mateos-White I, Espinosa A, Costa
            MR, Gil-Sanz C and Muller U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   2  (bases 1 to 3227)
  AUTHORS   Karemaker ID and Vermeulen M.
  TITLE     ZBTB2 reads unmethylated CpG island promoters and regulates
            embryonic stem cell differentiation
  JOURNAL   EMBO Rep 19 (4) (2018)
   PUBMED   29437775
  REMARK    GeneRIF: ZBTB2 is a novel DNA methylation-sensitive transcription
            factor that regulates cellular differentiation.
REFERENCE   3  (bases 1 to 3227)
  AUTHORS   Jeon BN, Choi WI, Yu MY, Yoon AR, Kim MH, Yun CO and Hur MW.
  TITLE     ZBTB2, a novel master regulator of the p53 pathway
  JOURNAL   J Biol Chem 284 (27), 17935-17946 (2009)
   PUBMED   19380588
  REMARK    GeneRIF: ZBTB2 is a potential proto-oncogenic master control gene
            of the p53 pathway and, in particular, is a potent transcription
            repressor of the cell cycle arrest gene p21 by inhibiting p53 and
            Sp1
REFERENCE   4  (bases 1 to 3227)
  AUTHORS   Okazaki N, F-Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S,
            Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H,
            Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK132308.1, AK173184.1 and BY444820.1.
            
            On Apr 7, 2009 this sequence version replaced NM_001033466.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132308.1, BY713747.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN02415122 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1698              AK132308.1         2-1699
            1699-3219           AK173184.1         5274-6794
            3220-3227           BY444820.1         402-409
FEATURES             Location/Qualifiers
     source          1..3227
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 2.06 cM"
     gene            1..3227
                     /gene="Zbtb2"
                     /gene_synonym="Gm1103"
                     /note="zinc finger and BTB domain containing 2"
                     /db_xref="GeneID:381990"
                     /db_xref="MGI:MGI:2685949"
     exon            1..264
                     /gene="Zbtb2"
                     /gene_synonym="Gm1103"
                     /inference="alignment:Splign:2.1.0"
     exon            265..449
                     /gene="Zbtb2"
                     /gene_synonym="Gm1103"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..1821
                     /gene="Zbtb2"
                     /gene_synonym="Gm1103"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein 2"
                     /protein_id="NP_001028638.2"
                     /db_xref="CCDS:CCDS56674.1"
                     /db_xref="GeneID:381990"
                     /db_xref="MGI:MGI:2685949"
                     /translation="MDLTNHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLAS
                     FSNYFKMLFVHQTSECVRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFL
                     HAYPLIQEASLASQGSFSHPEQVFPLASSLYGIQIADHQLRQATKMNLGPEKLGREPR
                     PQASRMNQEPVPETSQLSQLTSNLAQVNRTNITPEDPLQTSLSPELVSTPVPPPPPGE
                     ETNLEASSSDEQPSSLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIH
                     TGVPFTAGPPGEGRGPLSLCSNAADLGKDALEVPEAGMISDSELQHISDSPIIDGQQQ
                     SETPPPSDIADIDNLEQADQEREVKRRKYECTICGRKFIQKSHWREHMYIHTGKPFKC
                     STCDKSFCRANQAARHVCLNQSIDTYTMVDKQTLELCTFEEGSQMDNMLVQANKPYKC
                     NLCDKTFSTPNEVVKHSCQNQNSDVFALDEGRSVLLGSGDSEVTEPDHPVLASIKKEQ
                     ETVLLD"
     exon            450..3227
                     /gene="Zbtb2"
                     /gene_synonym="Gm1103"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctcccccc cggcgggagc cgctctcagc cgctttgcac tagtcgctcc gctctctcgg
       61 tcatgtgacc ttaacgtaac cggacaggaa aagccccgcc gccgccgccc gccgccgcgc
      121 cggagacacc gaccgcggcg gcagcagcaa gcagcagcag cagcagcaac gcggggcaga
      181 ggcggcggcg gggacagtta ggccaggccg cccggctctg cctcccctct cacgccccgc
      241 cgcggccgcc cgcaccggcg acagattttt taaaaaatgg atttgaccaa ccatggactt
      301 attctactgc agcagttaaa cgctcagcga gagtttggtt tcctgtgtga ctgcacggtt
      361 gcaatcggcg atgtgtactt caaggcacac aaatcagttc tcgcttcatt ctccaattac
      421 tttaagatgt tgtttgtcca tcagaccagt gaatgcgtcc gcctgaagcc cactgacata
      481 cagcctgaca tattcagcta tctgctccac ctgatgtaca cagggaagat ggccccacag
      541 ctcatcgacc ctgtgaggct agagcaaggg atcaaattcc tgcacgcata ccccctcatc
      601 caggaagcca gccttgccag ccaaggcagc ttttcccatc ccgagcaagt cttccctctg
      661 gcctcatcct tgtacggcat tcagattgca gaccatcagc tgagacaagc caccaagatg
      721 aatttagggc ctgagaaact tggacgggag cctaggccac aggcatccag gatgaaccag
      781 gagcctgtac cagagacctc gcagctgtcc cagctgactt caaacctagc ccaggtgaat
      841 cggacaaata taactcccga agaccccctg cagacctcgc tgtcacctga acttgtctcc
      901 acacctgtgc ctccccctcc tcctggggag gagaccaacc tagaggcctc ttcctctgac
      961 gagcagccat catcccttac gatcgcccac gtgaagccaa gcatcatgaa gaggaatgga
     1021 agcttcccca agtactatgc ctgccacctg tgcggccgtc gcttcacgct gcgcagcagc
     1081 ctgcgggagc acctgcagat ccacaccggg gtacccttca ctgcgggccc gccaggggaa
     1141 ggccgtgggc ccctgtctct ctgcagcaat gcggccgacc tgggcaagga tgctctggaa
     1201 gtaccggagg cggggatgat cagcgacagc gagctgcagc acatctccga ctcccccatc
     1261 atcgatgggc agcaacagtc ggagacccca ccgccctcag acattgcaga catcgacaac
     1321 ttggagcagg cagaccaaga gagggaagtg aagaggcgca agtatgagtg cacgatctgc
     1381 ggccgcaagt tcatccagaa aagccactgg cgtgagcaca tgtacattca cacgggcaaa
     1441 cccttcaagt gcagcacctg tgacaagagc ttctgtaggg ccaaccaggc cgcacgccac
     1501 gtgtgcctca accagagcat tgacacctac accatggtgg acaagcagac actggagctc
     1561 tgcacgttcg aggaaggcag ccagatggac aatatgctgg tgcaggccaa caagccctac
     1621 aagtgcaacc tgtgtgacaa gacgttctcc acacccaatg aggtggtcaa acactcctgc
     1681 cagaaccaga actcagacgt gttcgccctg gacgaggggc ggtcagtcct gcttggcagt
     1741 ggggactcag aagtaactga acctgaccac cctgtgttag cgtccatcaa aaaggaacag
     1801 gaaactgtgt tactagactg aatgttactt gtgtttttaa aaactgtcat tttttacaaa
     1861 gaatcttctc tattcgggac agtttctcca tggcatgata caaatgggcc ccagctcttt
     1921 cccgccccct tctcccagcc ccatctctgt aaggctttgt gcattataat cctgaactat
     1981 atttacttta attcagggga tattggaagg ataatggtca gtagtactta taaagaaata
     2041 ggttttgaga agttttagat tattgtaaaa acctacttgg agttaattaa gagtatataa
     2101 taaaacaact agaatataat ttggtcagct agaattatga ctgtccctgg gtgataagtc
     2161 ttccttctca cagaaacaaa gtcagaaaat acagcttctc agagataaag cgggcactgc
     2221 tatgcaaatc tggaaggtgt gggagacttt aaacccgaga gagagaatgt ttttaatctt
     2281 tgtcctctag gtgtctgatt tcagaatgta tcctttgaga ttatgtccgg ttaaggaaaa
     2341 tcactagtta agagaactac tttaacaaat gcaaaagagt aataatgtga cggcaatctt
     2401 catttttgga taaaacctga cgggctatga atttgtctgc gagcgaacgc atatggatac
     2461 ttgctacagg caaggggatt ggtgcgcatg ccttacccca tggctggcct ttttccaaga
     2521 agaacaagaa gatgctgtgt ttcggttcct gacacacttg ttttaaaatg agatttgaaa
     2581 acgtgatcct gtagaatgtc tttctgaaca acaatggcca atggtgagct tgtgtgcttg
     2641 tgtgtgagcc agctagccaa ctgcctgtaa atcagttgtg cgccctgcag tgacgcacca
     2701 cacaaggcaa gttgtgagcc aaaagtataa ctttaatgag ggctaaagtt gatgctgcct
     2761 gggcgccagg tgggatggga gcaggaggat taggagtttg aggccagcct gggcaagacc
     2821 ttgtccaaaa aataaaaaaa tgcaatgccc atagttcatt ggtgacatct actaaagcat
     2881 caaaaataac aaatcaggac acaaaatctt tttggaggaa aaataaacac aattgatttt
     2941 gttgtatatc ctccagtttt tgttaacacc tgaaattttc cccagtggcc taacagcatg
     3001 aaaagctgtc cattaatctt cccttgggcc aataagaaag tggtctccca ggatgcaacg
     3061 gagccagaag tgaggactaa ggggcagggt gagggtagtg catagctata ccctacgtgt
     3121 atgttagaaa ctgaatatcc caccatcctc ttatatgtat agttgagttc taagatttgt
     3181 aagtttttat acatcctttc attgaataaa catttaagta aatgggc
//
