LOCUS       NM_009541               3415 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus zinc finger and BTB domain containing 17 (Zbtb17),
            transcript variant 1, mRNA.
ACCESSION   NM_009541
VERSION     NM_009541.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Zhang,L., Toboso-Navasa,A., Gunawan,A., Camara,A., Nakagawa,R.,
            Finsterbusch,K., Chakravarty,P., Newman,R., Zhang,Y., Eilers,M.,
            Wack,A., Tolar,P., Toellner,K.M. and Calado,D.P.
  TITLE     Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TMBIM4
            safeguards IgG1+ GC B cell-positive selection
  JOURNAL   Sci Immunol 9 (94), eadk0092 (2024)
   PUBMED   38579014
REFERENCE   2  (bases 1 to 3415)
  AUTHORS   Jin,K., Shi,Y., Zhang,H., Zhangyuan,G., Wang,F., Li,S., Chen,C.,
            Zhang,J., Wang,H., Zhang,W. and Sun,B.
  TITLE     A TNFalpha/Miz1-positive feedback loop inhibits mitophagy in
            hepatocytes and propagates non-alcoholic steatohepatitis
  JOURNAL   J Hepatol 79 (2), 403-416 (2023)
   PUBMED   37040844
  REMARK    GeneRIF: A TNFalpha/Miz1-positive feedback loop inhibits mitophagy
            in hepatocytes and propagates non-alcoholic steatohepatitis.
REFERENCE   3  (bases 1 to 3415)
  AUTHORS   Yang,J., Hou,C., Wang,H., Perez,E.A., Do-Umehara,H.C., Dong,H.,
            Arunagiri,V., Tong,F., Van Scoyk,M., Cho,M., Liu,X., Ge,X.,
            Winn,R.A., Ridge,K.M., Wang,X., Chandel,N.S. and Liu,J.
  TITLE     Miz1 promotes KRAS-driven lung tumorigenesis by repressing the
            protocadherin Pcdh10
  JOURNAL   Cancer Lett 555, 216025 (2023)
   PUBMED   36538983
  REMARK    GeneRIF: Miz1 promotes KRAS-driven lung tumorigenesis by repressing
            the protocadherin Pcdh10.
REFERENCE   4  (bases 1 to 3415)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   5  (bases 1 to 3415)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3415)
  AUTHORS   Adhikary,S., Peukert,K., Karsunky,H., Beuger,V., Lutz,W.,
            Elsasser,H.P., Moroy,T. and Eilers,M.
  TITLE     Miz1 is required for early embryonic development during
            gastrulation
  JOURNAL   Mol Cell Biol 23 (21), 7648-7657 (2003)
   PUBMED   14560010
REFERENCE   7  (bases 1 to 3415)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 3415)
  AUTHORS   Herold,S., Wanzel,M., Beuger,V., Frohme,C., Beul,D., Hillukkala,T.,
            Syvaoja,J., Saluz,H.P., Haenel,F. and Eilers,M.
  TITLE     Negative regulation of the mammalian UV response by Myc through
            association with Miz-1
  JOURNAL   Mol Cell 10 (3), 509-521 (2002)
   PUBMED   12408820
REFERENCE   9  (bases 1 to 3415)
  AUTHORS   Harboe,T.L., Tommerup,N. and Tumer,N.
  TITLE     Assignment of Zfp100 to murine chromosome 4 band D3/E1 with
            radiation hybrid mapping
  JOURNAL   Cytogenet Genome Res 97 (3-4), 276A (2002)
   PUBMED   12861998
  REMARK    GeneRIF: The gene encoding Zfp100 has been assigned to murine
            chromosome 4 band D3/E1.
REFERENCE   10 (bases 1 to 3415)
  AUTHORS   Schulz,T.C., Hopwood,B., Rathjen,P.D. and Wells,J.R.
  TITLE     An unusual arrangement of 13 zinc fingers in the vertebrate gene
            Z13
  JOURNAL   Biochem J 311 (Pt 1) (Pt 1), 219-224 (1995)
   PUBMED   7575457
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY246264.1, AK134251.1 and BC145821.1.
            
            On Apr 3, 2008 this sequence version replaced NM_009541.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134251.1, U14556.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY246264.1         2-42
            42-717              AK134251.1         2-677
            718-2682            BC145821.1         591-2555
            2683-3415           AK134251.1         2643-3375
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 74.17 cM"
     gene            1..3415
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /note="zinc finger and BTB domain containing 17"
                     /db_xref="GeneID:22642"
                     /db_xref="MGI:MGI:107410"
     exon            1..130
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            131..217
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            218..424
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     CDS             220..2604
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 100; zinc finger and BTB domain-containing
                     protein 17; zfp-100; zinc finger protein 151; zinc finger
                     protein Z13; polyomavirus late initiator promoter-binding
                     protein"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein 17
                     isoform 1"
                     /protein_id="NP_033567.2"
                     /db_xref="CCDS:CCDS18875.1"
                     /db_xref="GeneID:22642"
                     /db_xref="MGI:MGI:107410"
                     /translation="MDFPQHSQRVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAA
                     CSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVASFLQMQ
                     DIVTACHTLKSLAEPSSTTGESADASAVEGGDKRAKDEKAAATMLSRLDQARGSSSTG
                     PGRELKEERGGQAESASSGAEQTEKADAPREPPPVELKPDPTSSMAAAEAEALSESSE
                     QEMEVEPASKGEDGQEEEGAGPATVKEEGMHLDNGEPPEENEESAGTDSGQELGMEGQ
                     NLRSGTYGDRTESKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAF
                     SDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFTT
                     SGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVG
                     NLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTHCQRQFADPGAL
                     QRHVRIHTGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLAN
                     HIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHV
                     KTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADE
                     TEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQT
                     DADFYQQYGPGSTWPAGQMLQAGELVFRPRDGTEGQPTLAESPPTAPDCLPPAE"
     exon            425..613
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            614..754
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            755..877
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1119
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1262
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1563
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1651
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1768
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1889
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2020
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            2021..2230
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            2231..2320
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..3415
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2684..2689
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /note="hexamer: AATAAA"
     polyA_site      2703
                     /gene="Zbtb17"
                     /gene_synonym="Lp-1; Miz1; mZ13; Zfp100"
                     /note="major polyA site"
ORIGIN      
        1 gggaagccag cgaggtcggt tccgcccggt tctaacatgg cggcgccctt tgtctgctgt
       61 gaagcgctgc ccccggcctt ctcgcggccg tgatgcacct ccatctgtgg tggggttcgg
      121 gacatggcag gtgatgagct ggaggcgggg agccgagctg gagatcctac aggcacactg
      181 tctgagaaga gagaccctgg ccttttggag atctgagcca tggatttccc ccagcacagc
      241 cagcgtgtct tggagcagct gaaccagcag cggcaactgg gcctcctctg tgactgcacc
      301 tttgtggtgg acggcgttga cttcaaggct cacaaggcgg tgctggcagc ttgcagcgag
      361 tacttcaaga tgctctttgt ggaccagaag gacgtggtgc acctagacat cagtaatgcg
      421 gcaggcctgg ggcaggtgct ggagttcatg tacactgcta agctgagcct tagccctgag
      481 aacgtggacg atgttctggc cgtggccagc ttcctccaga tgcaggatat tgtcacggcc
      541 tgccacacgc tcaagtccct cgctgagccg agcagcacca ctggggagag cgcagacgcc
      601 tcagctgtgg aaggaggaga caagagagcc aaagacgaga aggccgctgc caccatgttg
      661 agcaggctgg accaagcaag aggcagctcc tccacaggcc cgggcagaga actcaaggag
      721 gagcggggtg gccaggcaga aagtgcatcc agtggcgcag agcagacgga gaaggcagac
      781 gctccccggg agcctccacc tgtggagctc aagccggacc ccacaagcag catggcggct
      841 gcagaagccg aagccttatc agagagctca gagcaagaaa tggaagtgga gccagccagc
      901 aaaggagaag acggacaaga ggaagagggt gcagggcctg ccacagtcaa ggaagagggg
      961 atgcatctgg ataacgggga gcctcctgag gagaatgaag agtctgccgg cacagattct
     1021 gggcaggagc ttggcatgga gggtcagaac ctgcgctcgg gcacctacgg ggatcgcact
     1081 gagtccaagg cttacggctc catcatccac aagtgcgagg actgcgggaa ggagttcacg
     1141 cacacaggga acttcaaacg gcacatccgc atccacacgg gggagaaacc tttctcatgc
     1201 agggagtgca gcaaggcttt ctcggaccct gcagcgtgca aggctcatga gaagacacac
     1261 agcccgttga aaccctatgg gtgtgaggag tgtggcaaga gctacaggct catcagcctg
     1321 ctgaacctgc ataagaagag gcactccggg gaggcgcgct accgctgcgg ggactgtggc
     1381 aagctcttca ccacttcagg caacctcaag cgccaccagc tggtacacag tggccagaaa
     1441 ccctaccagt gcgactactg tggccgctcc ttctctgacc ccacctctaa gatgcgccac
     1501 ctggagactc acgacaccga caaggaacac aagtgtcctc actgcgacaa aaagttcaac
     1561 caggtgggga acctgaaggc ccacttgaag atccacattg ccgatggccc tcttaagtgc
     1621 cgggagtgcg ggaagcagtt caccacctca gggaacctca agcggcacct gcggatccac
     1681 agtggggaga agccgtacgt atgcacccac tgtcagcggc agtttgccga cccaggcgcg
     1741 ctacagcggc acgtccggat ccacacgggt gagaagccgt gccagtgtgt gatatgtggt
     1801 aaggccttta cccaagccag ctccctcatc gcccatgtac gccaacacac gggggagaag
     1861 ccctacgtct gtgaacgctg tggcaagaga tttgtccagt ccagccagtt ggccaaccac
     1921 atccgtcacc atgacaacat ccgaccgcac aagtgcagcg tgtgtagcaa ggccttcgtg
     1981 aatgtggggg acctgtccaa gcacattatc atccacaccg gagagaagcc ttatttgtgt
     2041 gacaaatgtg gccgtggttt caaccgggta gacaacctgc gttctcatgt aaagaccgtg
     2101 catcagggca aggcgggcat caagatcctg gagccagaag agggtggtga ggtcagcgtg
     2161 gtcactgtgg acgacatggt caccctggcc actgaggctc tggcagcgac agcggtcact
     2221 cagctaacag tggtaccagt gggggccgca gtgacagctg acgagacgga agtactcaaa
     2281 gctgagatca gcaaagctgt caagcaagtg caggaagaag accccaacac ccacatcctc
     2341 tacgcttgtg attcctgtgg ggacaagttc ctggatgcca atagcctagc ccagcatgtt
     2401 cggatccaca cagcccaggc actggtcatg ttccagacgg atgcggactt ctaccagcag
     2461 tatgggccag gcagcacgtg gccagccggg cagatgctgc aggctggaga gctcgtcttc
     2521 cgtcctaggg atgggactga gggccaaccc acactggcag aaagtccacc cacagctcct
     2581 gattgcctac cacctgccga gtgagcaggt ggcctctgac tgtttattta aggatggatg
     2641 gcaccctagg actcagaagg tgctcctgcc ccattcccta gagaataaat gattattttc
     2701 taatgttgcc tgtggtccct gtgtcaccag taggtgggga acaggcacct atacaagtga
     2761 caatttaata gtgtccctca tgcaaagtgg agcttcatac catcctaagc tattcagcca
     2821 caggtggcgc cccatagctg gcgtgcaccc aagaggccgg taccagggtc cagccagagc
     2881 agccacccag ggacagacca ccggctggct cctcagtgaa gtaaggcctg gtacctgctt
     2941 tacctaggcc acagcagcgc cgtgctgtgg cagtactcac tgctgcatgc agtgtgctac
     3001 caggatggca aggggacagg aagggagcag gggccccagg gacctgggca ggcctgctct
     3061 atagtcccaa ctgcattccc cagaaaacat tggtgcctcg gcttcttctt gagggtaggt
     3121 acagaattag ccccaggaat agtgggctcc tggccactac aaggagtgat ggcaccagca
     3181 ggagccagca agggggcgga gaaagaaagg gtctcagtat gtaccagagt ctgaggtgcc
     3241 tgccgtccca gtggcctagg ctgagcacag gggaaaggct ccttgttccc ggatgtgggg
     3301 tggggtctgc tgtgcaagtc aagaaaccga ggcgcccact gagtgacaac caccttcaca
     3361 cctgaggtgt tttgtatttt ttaataaagt ttgtaatcca atggacacac agaac
//
