LOCUS       NM_173026               4999 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus zinc finger and BTB domain containing 11 (Zbtb11),
            mRNA.
ACCESSION   NM_173026 XM_001480244 XM_001481121
VERSION     NM_173026.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4999)
  AUTHORS   Cao,H., Naik,S.H., Amann-Zalcenstein,D., Hickey,P., Salim,A.,
            Cao,B., Nilsson,S.K., Keightley,M.C. and Lieschke,G.J.
  TITLE     Late fetal hematopoietic failure results from ZBTB11 deficiency
            despite abundant HSC specification
  JOURNAL   Blood Adv 7 (21), 6506-6519 (2023)
   PUBMED   37567157
  REMARK    GeneRIF: Late fetal hematopoietic failure results from ZBTB11
            deficiency despite abundant HSC specification.
REFERENCE   2  (bases 1 to 4999)
  AUTHORS   Garipler,G., Lu,C., Morrissey,A., Lopez-Zepeda,L.S., Pei,Y.,
            Vidal,S.E., Zen Petisco Fiore,A.P., Aydin,B., Stadtfeld,M.,
            Ohler,U., Mahony,S., Sanjana,N.E. and Mazzoni,E.O.
  TITLE     The BTB transcription factors ZBTB11 and ZFP131 maintain
            pluripotency by repressing pro-differentiation genes
  JOURNAL   Cell Rep 38 (11), 110524 (2022)
   PUBMED   35294876
  REMARK    GeneRIF: The BTB transcription factors ZBTB11 and ZFP131 maintain
            pluripotency by repressing pro-differentiation genes.
REFERENCE   3  (bases 1 to 4999)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   4  (bases 1 to 4999)
  AUTHORS   Dietrich,J.E., Panavaite,L., Gunther,S., Wennekamp,S., Groner,A.C.,
            Pigge,A., Salvenmoser,S., Trono,D., Hufnagel,L. and Hiiragi,T.
  TITLE     Venus trap in the mouse embryo reveals distinct molecular dynamics
            underlying specification of first embryonic lineages
  JOURNAL   EMBO Rep 16 (8), 1005-1021 (2015)
   PUBMED   26142281
REFERENCE   5  (bases 1 to 4999)
  AUTHORS   Ficker,M., Powles,N., Warr,N., Pirvola,U. and Maconochie,M.
  TITLE     Analysis of genes from inner ear developmental-stage cDNA
            subtraction reveals molecular regionalization of the otic capsule
  JOURNAL   Dev Biol 268 (1), 7-23 (2004)
   PUBMED   15031101
REFERENCE   6  (bases 1 to 4999)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 4999)
  AUTHORS   Balcarek,J.M. and Cowan,N.J.
  TITLE     Structure of the mouse glial fibrillary acidic protein gene:
            implications for the evolution of the intermediate filament
            multigene family
  JOURNAL   Nucleic Acids Res 13 (15), 5527-5543 (1985)
   PUBMED   2994002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171202.1.
            
            On or before Sep 19, 2009 this sequence version replaced
            XM_001480244.1, XM_001481121.1, NM_173026.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.885710.1,
                                           SRR9219380.13273.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-568               AC171202.1         121540-122107       c
            569-804             AC171202.1         115081-115316       c
            805-1036            AC171202.1         113505-113736       c
            1037-1872           AC171202.1         104817-105652       c
            1873-2049           AC171202.1         104293-104469       c
            2050-2295           AC171202.1         97660-97905         c
            2296-2440           AC171202.1         95188-95332         c
            2441-2558           AC171202.1         93085-93202         c
            2559-2717           AC171202.1         89843-90001         c
            2718-2893           AC171202.1         89561-89736         c
            2894-4999           AC171202.1         86998-89103         c
FEATURES             Location/Qualifiers
     source          1..4999
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 33.74 cM"
     gene            1..4999
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /note="zinc finger and BTB domain containing 11"
                     /db_xref="GeneID:271377"
                     /db_xref="MGI:MGI:2443876"
     exon            1..568
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..3411
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein
                     11"
                     /protein_id="NP_766614.2"
                     /db_xref="CCDS:CCDS49874.1"
                     /db_xref="GeneID:271377"
                     /db_xref="MGI:MGI:2443876"
                     /translation="MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRG
                     GTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWW
                     RGILKQVKDYIKQCSKCQEKLDRSRPISDASEMLEELGLDLDSGEESNESEDDLSNFT
                     SPPSTASKSSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTL
                     LIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTS
                     VLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLA
                     AHNGTTTPPGTRNEATTTLSGELGHCEIVLLVNGELPEAEQNGEPEQQPAPQASPEAE
                     ASVSPVEGIPEPHPEMGTASLAKESNQPESAVTREDGIVASVHPKISKENVTNASQED
                     SDTGNDTSPEDIGAKDCPDHSQSPGQPSKDEDTLTEATEKTDSGPDDDTYRSRLRQRS
                     VNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRDAKESTEETAH
                     KCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKEAPTS
                     SSSNSTSTEASGGSSEKGRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCG
                     KTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSICGKS
                     FHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDK
                     CYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERV
                     CDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCP
                     VCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQEQ
                     ESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLS
                     EVAEAIQTVEVEVAHMPEAE"
     exon            569..804
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            805..1036
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1872
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..2049
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2295
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2440
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2441..2558
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2717
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2718..2893
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     exon            2894..4999
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4968..4973
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /note="hexamer: AATAAA"
     polyA_site      4999
                     /gene="Zbtb11"
                     /gene_synonym="9230110G02Rik; ZNF-U69274"
                     /note="major polyA site"
ORIGIN      
        1 ggtgcagcag ccattttgtc agtcgccagc ggatcccgcg cgctgccgaa gtgcagttcc
       61 ccctggttac caggtggtcg gttcttcccc tccgcgctgc cggcgggcgg gcaggcgggc
      121 gccctcggag agagagagcg cccaccacag gcgtcgcctt cgctcctccc cgggtcgccg
      181 cggcccctct cccgagccgc ggcgctgtct gcctctcctt accactgaca ggcgcccccg
      241 agggcgctgc cggcggctat gtcaagcgag gagagctacc gggccatcct gcgctacctg
      301 acgaacgaac gcgagcccta tgcgccgggc accgagggca atgtcaagcg gaagatccgc
      361 aaggccgccg cctgctacgt cgtgcgcggc gggaccctct actaccagcg gcggcagcgg
      421 caccgcaaga ccttcgccga gctggaggtg gtgttgcagc cggagcgtcg ccagggcctc
      481 atcgaggcgg cccatttggg ccccgggggc acccaccaca cccggcacca gacctggcac
      541 gacctgtcca agacctactg gtggcgaggt atattaaagc aagttaaaga ttacataaaa
      601 cagtgtagca aatgtcagga gaagctcgat cgctcccgtc caatatcgga tgcttcggaa
      661 atgttggaag agttggggtt ggatcttgac tctggagaag aaagtaatga gtcggaggat
      721 gacctgagca acttcacctc ccctccatcc acagcctcca agtcttccaa aaagaagcca
      781 gtgtcgaaac atgagctggt gtttgttgac accaaaggag tggtcaaacg gtcctctcca
      841 aagcattgcc aggcggttct gaaacagttg aatgagcaga ggctttccaa ccagttctgt
      901 gacgtcacat tgctcatcga gggggaggag tacaaagcgc acaagtctgt cctctcggct
      961 aatagtgaat attttcgaga tctttttatt gaaaaaggag cagtttctag tcacgaggct
     1021 gttgtggatc tttctggttt ctgtaaagca agcttccttc ctttgctgga atttgcctat
     1081 acttctgtac taagttttga cttttgtagc atggctgatg tagccgtctt agctcgccac
     1141 ctttttatgt cagaagtttt agaaatttgt gaaagtgtac ataaactaat ggaagaaaaa
     1201 cagcttacag tgtataagaa aggagaagtt caaacggttg catctactca ggacttagca
     1261 gcacacaatg gaactacaac accacctggc actaggaatg aagcaaccac aactttgtcc
     1321 ggtgaacttg ggcattgtga aattgtactg ctggtaaatg gagaattgcc agaggcagag
     1381 cagaatgggg agccagagca gcagcctgca cctcaggctt ctccagaggc tgaagctagt
     1441 gtgtcccctg tagaaggtat acctgagccc caccctgaaa tgggaactgc aagcttagca
     1501 aaagaaagca accaaccaga gtccgcagtc accagagaag atggcatagt tgctagtgtt
     1561 catcctaaaa tctcaaaaga gaatgttacc aacgcctccc aagaggacag tgatacagga
     1621 aacgatacat cacctgagga catcggtgcc aaagactgtc cagatcatag tcagagccct
     1681 ggccaacctt caaaggatga ggacactcta actgaagcta cagaaaagac agactcaggc
     1741 ccagatgatg atacttatag gagcaggctt aggcagcggt ctgttaatga agggggctat
     1801 atccggctac acaagggcat ggagaaaaag ttacagaagc ggaaagccat ctctaagtca
     1861 gcagttcaac aggtggccca gaaattagtt caaagaggaa aaaagatgaa acaaccaaaa
     1921 cgggatgcta aggagagcac cgaagaaacg gctcataaat gtggtgaatg tggaatggtt
     1981 tttccgagac gatatgcctt tataatgcac acattgaaac atgaaagagc tagagattac
     2041 aaatgtccgt tatgtaagaa acagtttcag tatagtgcct cattacgagc acaccttatt
     2101 cgacatacaa gaaaagaggc acccacttca tcctcatcca attccacatc tactgaggcg
     2161 tcgggaggat catctgagaa gggaagaacc aaaagagaat ttatatgttc tatatgtgga
     2221 aggacattac ctaaattata ctctctccgc atacatatgc taaagcacac gggtgtaaag
     2281 ccgcatgcat gccaggtgtg tggaaaaact tttatctata agcatggtct aaaattgcat
     2341 caaagtctgc atcaatcaca aaagcagttt cagtgtgaac tgtgtgtcaa gtcatttgtt
     2401 accaagcgga gtcttcagga acatatgagt attcacacag gagagtccaa gtacttctgc
     2461 tcaatttgtg gaaagtcttt tcataggggc tctggactta gcaagcacct taagaaacac
     2521 cagccaaagc ctgaagttcg aggctatcat tgtactcaat gtgaaaaaag tttttttgaa
     2581 gccagagatc tacgccagca tatgaacaaa catcttggtg tgaagccatt ccagtgccag
     2641 ttttgtgata agtgttacag ctggaagaaa gattggtatt cccatgtgaa gtcccattct
     2701 gtcactgagc cttacaggtg taatatatgc ggcaaagaat tttatgaaaa agctttattc
     2761 agaagacatg taaagaaggc cacccatggg aagaaaggaa gagcaaagca aaacctggag
     2821 cgggtgtgtg atcagtgtgg gaggaagttc acgcagctga gagagtacag gagacacatg
     2881 aacaaccatg aaggcgttaa gcctttcgag tgcttaacat gtggagtagc gtgggctgat
     2941 gcccgatcac taaagcgtca tgtccgaaca catactggtg aacggcccta tgtgtgtcct
     3001 gtgtgtagtg aagcctacat tgatgctcga acacttcgta agcatatgac taaattccac
     3061 agagactatg tgccttgcaa aattatgctg gaaaaagaca ctctgcagtt tcataaccaa
     3121 ggaacacaag tggaacatgc tgtcagcatc ttaactgcag acatgcagga acaagaaagc
     3181 agtgggcctc aagaactgga gactgtggtg gtgacaggag aaactatgga agttcttgaa
     3241 gctgtggcag ctactgagga gtgtccgtcg gtgtctaccc tctctgacca aagcattatg
     3301 caagtggtta actatgtgct ggcgcagcag caagggcaga agctgtctga agttgcagaa
     3361 gccattcaga ctgttgaagt ggaggttgca catatgccag aggcagagtg agtgctgctg
     3421 tcacgggcaa gcctgcccga ggagctcacc gaggacgcgt ttacagttta tgtcaccact
     3481 atgcagtcct gggttgtgga actctgggtt gttggtgaca tcactagtct tcttgtctgg
     3541 ccagtgagtt ctgcagaaag tcctctttct gtaaagaaat tgaaaacaat ctgttggatg
     3601 gaagtagttg atcatggtat gccttttatg aattaatgtt tatatttgac tttattttat
     3661 tacatacttt gaatttaaaa ggctgcagtt agtgtctctt ctgttgtctg tttacagtac
     3721 agagggtctg tgactagttg ctgtttgtgg atttaaaaat tctaatataa aaagcgtatc
     3781 tgtaagatgc ataaatatat tacatttaaa aaatgcttta gagctatgat tcttgactct
     3841 atttatttta actgcttcta agtcaagaat ctattctatc ttaaagcact tgagttctgt
     3901 gttataatca agtttgtata atttatttat ctctatggga gacccatatg caaagctaat
     3961 tttaaaatac cattaaaatg catgagatgc ctattagagc cttattatac tatctcttca
     4021 aggcaagtat tggccaggag aaaagagtgc tgttatcgaa cactgttgcc gggaagtttc
     4081 tgcttggtaa cactgactat gaatgaaaaa aaatcaaccc tgtttctttt gctgaagaat
     4141 gaacaagtta gagaagaagt taagtttgat atgtttatct tttgtatcat gtttgtttaa
     4201 atttgttgaa aaactacaca tctatagtag tagtatggaa gtcatataat tgttaatttc
     4261 agaatgttga aaattcttca gtgcaaccct tagtatactg tattacataa aaaattgatt
     4321 atgacactat caaattgctg aaagtatttt caaaagttac tttaaaacta aattataccc
     4381 attcatgtgt ttgatttttt tttgttgttt tttttttttt ttaatttctc acttctgagt
     4441 tgtcagatac tcagattttg aaaataacca cggggagatg ccacagctct ctctagaaga
     4501 ctatcgttca agctaggatt gttacaatta agcttttcga tattagaagc tttcttaaga
     4561 tatataatta agatatataa aatagattat atgtaaatca ttcctaaagc acaagaagtg
     4621 aatgtgcctt gatgtacata tataatatta gaacgcttat tccagtttac tttgaaaatg
     4681 gctttaaggt taaggagtaa tgtgatctct ctgcatgcat cttcttgcat acggaatgtg
     4741 tgcatttgca aattcgtcat cgttttaaaa gctgtgtggc tttcagtttt aaaagtgaat
     4801 ttatatacag ctcataactt cataaaggct attccttggt catgtccacc agttagtgag
     4861 aaagtgtttc aatgaaacta aaatttgaaa ttgtcttatg ttccactttc accactgtta
     4921 gatttagtta aatgtataag attattaatg tatatcagaa atatataaat aaaagatgtt
     4981 cagtcttgtt aaaagcaaa
//
