LOCUS       NM_028106               2325 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus zinc finger, BED type containing 3 (Zbed3), transcript
            variant 1, mRNA.
ACCESSION   NM_028106
VERSION     NM_028106.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2325)
  AUTHORS   Zhang,W., Zhang,R., Wu,L., Zhu,C., Zhang,C., Xu,C., Zhao,S.,
            Liu,X., Guo,T., Lu,Y., Gao,Z., Yu,X., Li,L., Chen,Z.J., Qin,Y. and
            Jiao,X.
  TITLE     NLRP14 deficiency causes female infertility with oocyte maturation
            defects and early embryonic arrest by impairing cytoplasmic UHRF1
            abundance
  JOURNAL   Cell Rep 42 (12), 113531 (2023)
   PUBMED   38060382
REFERENCE   2  (bases 1 to 2325)
  AUTHORS   Meng,T.G., Guo,J.N., Zhu,L., Yin,Y., Wang,F., Han,Z.M., Lei,L.,
            Ma,X.S., Xue,Y., Yue,W., Nie,X.Q., Zhao,Z.H., Zhang,H.Y., Sun,S.M.,
            Ouyang,Y.C., Hou,Y., Schatten,H., Ju,Z., Ou,X.H., Wang,Z.B.,
            Wong,C.C.L., Li,Z. and Sun,Q.Y.
  TITLE     NLRP14 Safeguards Calcium Homeostasis via Regulating the K27
            Ubiquitination of Nclx in Oocyte-to-Embryo Transition
  JOURNAL   Adv Sci (Weinh) 10 (27), e2301940 (2023)
   PUBMED   37493331
REFERENCE   3  (bases 1 to 2325)
  AUTHORS   Fu,A., Yu,Z., Zhang,E. and Song,J.
  TITLE     Long noncoding RNA ZBED3-AS1 restrains breast cancer progression by
            targeting the microRNA-513a-5p/KLF6 axis
  JOURNAL   Thorac Cancer 12 (20), 2719-2731 (2021)
   PUBMED   34427978
  REMARK    GeneRIF: Long noncoding RNA ZBED3-AS1 restrains breast cancer
            progression by targeting the microRNA-513a-5p/KLF6 axis.
REFERENCE   4  (bases 1 to 2325)
  AUTHORS   Ruan,X., Liu,G., Zhou,J., Chen,P., Sun,C., Liu,W., Wu,C., Hou,L.,
            Yin,B., Qiang,B., Shu,P. and Peng,X.
  TITLE     Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical
            Layers Formation in Developing Brain
  JOURNAL   Cereb Cortex 31 (9), 4078-4091 (2021)
   PUBMED   33822906
  REMARK    GeneRIF: Zbed3 Is Indispensable for Wnt Signaling Regulation of
            Cortical Layers Formation in Developing Brain.
REFERENCE   5  (bases 1 to 2325)
  AUTHORS   Qin,D., Gao,Z., Xiao,Y., Zhang,X., Ma,H., Yu,X., Nie,X., Fan,N.,
            Wang,X., Ouyang,Y., Sun,Q.Y., Yi,Z. and Li,L.
  TITLE     The subcortical maternal complex protein Nlrp4f is involved in
            cytoplasmic lattice formation and organelle distribution
  JOURNAL   Development 146 (20) (2019)
   PUBMED   31575650
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2325)
  AUTHORS   Fan,C., Jiang,G., Zhang,X., Miao,Y., Lin,X., Luan,L., Xu,Z.,
            Zhang,Y., Zhao,H., Liu,D. and Wang,E.
  TITLE     Zbed3 contributes to malignant phenotype of lung cancer via
            regulating beta-catenin and P120-catenin 1
  JOURNAL   Mol Carcinog 54 Suppl 1, E138-E147 (2015)
   PUBMED   25263389
REFERENCE   7  (bases 1 to 2325)
  AUTHORS   Jia,Y., Yuan,L., Hu,W., Luo,Y., Suo,L., Yang,M., Chen,S., Wang,Y.,
            Liu,H., Yang,G. and Li,L.
  TITLE     Zinc-finger BED domain-containing 3 (Zbed3) is a novel secreted
            protein associated with insulin resistance in humans
  JOURNAL   J Intern Med 275 (5), 522-533 (2014)
   PUBMED   24283382
REFERENCE   8  (bases 1 to 2325)
  AUTHORS   Hayward,A., Ghazal,A., Andersson,G., Andersson,L. and Jern,P.
  TITLE     ZBED evolution: repeated utilization of DNA transposons as
            regulators of diverse host functions
  JOURNAL   PLoS One 8 (3), e59940 (2013)
   PUBMED   23533661
REFERENCE   9  (bases 1 to 2325)
  AUTHORS   Chen,T., Li,M., Ding,Y., Zhang,L.S., Xi,Y., Pan,W.J., Tao,D.L.,
            Wang,J.Y. and Li,L.
  TITLE     Identification of zinc-finger BED domain-containing 3 (Zbed3) as a
            novel Axin-interacting protein that activates Wnt/beta-catenin
            signaling
  JOURNAL   J Biol Chem 284 (11), 6683-6689 (2009)
   PUBMED   19141611
  REMARK    GeneRIF: Zbed3 is a novel Axin-binding protein that is involved in
            Wnt/beta-catenin signaling modulation.
REFERENCE   10 (bases 1 to 2325)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BY776906.1, BY776946.1,
            BU709250.1, AK011319.1, AK162164.1 and BC085478.1.
            
            On Oct 28, 2014 this sequence version replaced NM_028106.2.
            
            Summary: This gene encodes a member of the zinc finger protein
            superfamily. This protein may regulate the Wnt/beta-catenin
            signaling pathway. This protein may be involved in insulin
            resistance and type 2 diabetes in humans. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, Oct
            2014].
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 BY776906.1         2-2
            2-88                BY776946.1         3-89
            89-412              BU709250.1         1-324
            413-805             AK011319.1         1-393
            806-2306            AK162164.1         453-1953
            2307-2325           BC085478.1         1890-1908
FEATURES             Location/Qualifiers
     source          1..2325
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 49.38 cM"
     gene            1..2325
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /note="zinc finger, BED type containing 3"
                     /db_xref="GeneID:72114"
                     /db_xref="MGI:MGI:1919364"
     exon            1..520
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            521..2307
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             535..1221
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /note="axin-interacting protein; zinc finger, BED domain
                     containing 3"
                     /codon_start=1
                     /product="zinc finger BED domain-containing protein 3"
                     /protein_id="NP_082382.1"
                     /db_xref="CCDS:CCDS26696.1"
                     /db_xref="GeneID:72114"
                     /db_xref="MGI:MGI:1919364"
                     /translation="MKSKKPLKITMEDSRRLNDPAEQGGLCPAPVGPSYSEAWGYFHL
                     DPAQPRHRMMSAWATCRLCGLQVGGLPNFQMWTRALCQHLSDVHLPELKKSAAPSSPT
                     TMPCPPPPSPTMAAEGDWARLLEQMGELAMRGSQRELELERREAALMQAELELERKRQ
                     ALKQEAQSVEQERHQLQVEREALSKWIKKQSPGAQVPEPPSPLPLLPKEDPDIHDNNS
                     DNDMVTKVLL"
     regulatory      2286..2291
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2307
                     /gene="Zbed3"
                     /gene_synonym="0610037K01Rik; 2610005H11Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtaaatcacg cagacgctgt taactgaata taatgaagac aaaggtagtt ccctgtgctg
       61 gtggtttggg tggacacctt ttcctcctaa gaccttgatt gcaaggactt ctgactagtg
      121 ccatatcaga ggccttaatc tgtaagaatg cgagcgagca gtgcgcccag ctgaggatct
      181 ggacccgctg aatccaaggg cttggaaggt taacgcgcaa acgtgcagag ccacggttaa
      241 aacgctttca gcatccctgc gctattattg caccgtttaa aaacctccga cagatttcaa
      301 ttcgttaaac tagttctcca tccgttactc taaactcctc ccggaccgga tggtttagca
      361 gcggcgcccc ggcgtccaga ccacgcgtca ccgcccccca tggacgcccc gagacgcgca
      421 aattgagcgc tgtgtcttta agggggaatc ggccttttcc gtccaggaca aaatgtctgc
      481 gaggagcccg gaggcgaggg gcgaccatcg cggcgtccgg acactgcaga aggaatgaag
      541 agtaaaaagc ccctgaagat caccatggaa gacagccgga ggcttaatga cccagcggaa
      601 caaggcggcc tctgtcccgc gcccgtgggg ccatcatact ccgaggcctg gggctacttc
      661 catctggacc cagctcagcc taggcaccgg atgatgagcg cctgggccac ctgccgcctg
      721 tgcgggctgc aagtgggtgg cctccccaac ttccagatgt ggacgcgggc gctgtgccag
      781 cacctgagtg atgtgcacct gccggagctg aagaagagcg ctgctccgag ctcgccgacc
      841 accatgccct gcccgccgcc gcccagcccc accatggctg ccgagggcga ctgggcacgc
      901 ctgttggagc agatgggtga gctggccatg cggggcagcc agcgggagct ggagctggag
      961 cggcgcgagg cggccctaat gcaggcggaa ctcgagctgg agcgcaagcg ccaggctctg
     1021 aagcaggagg cacaatccgt ggagcaggag cgccaccagc tacaggtaga gcgtgaagca
     1081 ctgagtaagt ggataaagaa gcagagcccc ggtgcacagg tcccggaacc gccctctccc
     1141 ctgcctctgc tccccaagga ggaccctgac atccatgaca acaacagtga caatgatatg
     1201 gtcaccaagg tcctgctgta gcatgactga ccgctccatg tgtaaaccta accataggct
     1261 gcaggcgcgg cagcgccccc aagtccagta gcctggatta ggtacacaga caggatagtc
     1321 ctcacagcta cctctttgta gtcctgaagg cattttaagc cagaaggttc tctaaacacc
     1381 agagactcat cacaccgcga gccttttgtg gggaaggggc atggttttta tccaggaacc
     1441 tggtccactc ttttccaaat gtataatctt gacttggcac caccatgttc cagaaaggaa
     1501 ccttgagtat cactgactcc ctggctccct gccttcagca tctatagaac cccaccttgg
     1561 accagtccca aagagacccc tttttgttcc tgtccctcat gtggctaacc caaggcagtg
     1621 agcaccctta aatcatcttt gcctggatga gacccagcga caagtacatt ctcccatttt
     1681 cttgtcttgc atcttgccac cttactagca agacatcggc cactagggag aagtttcttg
     1741 ccccacaggt ccccacagac ctccccctga accaaaagaa aaaccagagg ccgcgcctcc
     1801 ccactgcctt agagtcaacc cctatctcat tccctccctt tcttcagccc gctcctcccg
     1861 cccccccccc atgcctccta tcccagaaag tcaagatgtc ctcgttgccc acacttgcca
     1921 ctttgcatct caccatgttt gtttcatgtc ctgcgcatgc taagctagca cccagaagcc
     1981 acacatggct tccccagccc tgacctgcct tctgaagccc cttcttttgg aggtgcactg
     2041 tgcctttcta aaggcttttg ttttgaggta gggtcttttt aaggtagatt aaacgtaaat
     2101 gcctttttta tgagacgttt gaaagggcaa tctgaccatt atattttata aaaaccacat
     2161 acattctagg acaaatcact gcatttgatt tgggaaaaat gtttctatga ccgacgtgaa
     2221 atataaccct gacagattaa tttcatgaaa tacttgtagt tttgcaacac tccttttttt
     2281 tttttaataa acttttattt atctgcaaaa aaaaaaaaaa aaaaa
//
