LOCUS       NM_027166               2211 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus yippee like 5 (Ypel5), transcript variant 1, mRNA.
ACCESSION   NM_027166 XM_356970
VERSION     NM_027166.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2211)
  AUTHORS   Jeidane,S., Scott-Boyer,M.P., Tremblay,N., Cardin,S., Picard,S.,
            Baril,M., Lamarre,D. and Deschepper,C.F.
  TITLE     Association of a Network of Interferon-Stimulated Genes with a
            Locus Encoding a Negative Regulator of Non-conventional IKK Kinases
            and IFNB1
  JOURNAL   Cell Rep 17 (2), 425-435 (2016)
   PUBMED   27705791
  REMARK    GeneRIF: Ypel5 is a negative regulator of IFNB1 production and
            innate immune responses that interacts functionally and physically
            with TBK1/IKBKE kinases
REFERENCE   2  (bases 1 to 2211)
  AUTHORS   Hosono,K., Noda,S., Shimizu,A., Nakanishi,N., Ohtsubo,M.,
            Shimizu,N. and Minoshima,S.
  TITLE     YPEL5 protein of the YPEL gene family is involved in the cell cycle
            progression by interacting with two distinct proteins RanBPM and
            RanBP10
  JOURNAL   Genomics 96 (2), 102-111 (2010)
   PUBMED   20580816
REFERENCE   3  (bases 1 to 2211)
  AUTHORS   Hosono,K., Sasaki,T., Minoshima,S. and Shimizu,N.
  TITLE     Identification and characterization of a novel gene family YPEL in
            a wide spectrum of eukaryotic species
  JOURNAL   Gene 340 (1), 31-43 (2004)
   PUBMED   15556292
REFERENCE   4  (bases 1 to 2211)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163036.2, CA556143.1, AK169241.1 and BQ176693.1.
            
            On Oct 26, 2017 this sequence version replaced NM_027166.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049096.1, AK169241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                AC163036.2         103695-103707       c
            14-74               CA556143.1         1-61
            75-2122             AK169241.1         2-2049
            2123-2211           BQ176693.1         1-89                c
FEATURES             Location/Qualifiers
     source          1..2211
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 44.7 cM"
     gene            1..2211
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /note="yippee like 5"
                     /db_xref="GeneID:383295"
                     /db_xref="MGI:MGI:1916937"
     exon            1..164
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /inference="alignment:Splign:2.1.0"
     exon            165..329
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /inference="alignment:Splign:2.1.0"
     CDS             189..554
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /EC_number="1.5.8.4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     yippee protein homolog; protein yippee-like 5"
                     /codon_start=1
                     /product="protein yippee-like 5 isoform 1"
                     /protein_id="NP_081442.1"
                     /db_xref="CCDS:CCDS28963.1"
                     /db_xref="GeneID:383295"
                     /db_xref="MGI:MGI:1916937"
                     /translation="MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFL
                     FNKVVNLQYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVILE
                     RALVRESEGFEEHVPSDNS"
     exon            330..2194
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1240..1245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /note="hexamer: AATAAA"
     polyA_site      1257
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /note="major polyA site"
     regulatory      2166..2171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
                     /note="hexamer: AATAAA"
     polyA_site      2194
                     /gene="Ypel5"
                     /gene_synonym="2310076K21Rik; CGI-127"
ORIGIN      
        1 gcctgaaggg agggcggggc cacgcccggt gattgacgcc gaggcccgac cgaggagagg
       61 cggggccaag gcctgactaa acctgaagac ttgggaggcc gaggtgggct tcgacccagc
      121 tgaggagcga agagctgctg gcagcgccga ttcccagcac gccgcttttt agaacttcag
      181 ttgtcaaaat gggcagaatc tttcttgacc atatcggtgg tacccgtctg ttttcttgtg
      241 caaactgtga tacaatcctg accaatcgct cagaactcat ctctactcgg ttcacaggcg
      301 ccactggtag agcatttctt tttaacaagg tagttaactt gcagtacagt gaagttcaag
      361 atcgggtcat gctcactggc cgccacatgg ttcgagatgt gagctgcaaa aactgcaata
      421 gcaaactggg atggatctat gagtttgcta ctgaagacag ccagcgttat aaggaaggcc
      481 gtgtgatcct ggaacgtgca ctagttcgag agagtgaagg ctttgaagag catgtaccat
      541 ctgataactc ttgaagaaaa aagataaatc catcttttcc caggtctcct tcactgaaaa
      601 caaaatctcc ttacatacac tgtcacctta gcatcagagt cggattcatg aactgcggaa
      661 caagaggtta tgagaatcta agatggaacc tttttttctt tctttttttt ttttttaatt
      721 ttgtattttc catccaacag cagtttgtag agagaatttt atgcatatgc tggtaatttt
      781 ttccctgtgt ttacatcttg agacagaaga gtttgcagct acatggtggg ctatgtgagg
      841 gaaaaaaatt ggggtcctta gagtgaaaag gagtgttttg tgtatatttt gagtggagaa
      901 tatgtcaaga gcatggtttt taaatttatt tgggctttat ttaaaatttt ctttttaacc
      961 cagttatttc acttaatttg ctagcttcaa gaagagatcc gaatctgtgc ccagcgctgg
     1021 aggctcagtg ttagcatggc ttgtgctggc cagtgtgcca tattcttgtt ggagaggaac
     1081 tgtagcacca gaacccattc ttccttgtca gtcttgaccc acagatgtca ccacccctag
     1141 ttccttgtca ccatggactt ggtgttgatt ggaaactttc tgaaatgggg cagaactgct
     1201 tggttgtctt ttcccatgta acttaagcat agtaatataa ataaagtggt agttggatgt
     1261 tttggtcctc tgttactttt aaaaataact aataagaaag caaaagtttg atagtgattt
     1321 tcttagtagt tagtgattcc tctcaagctt aagcgatatt gactgtgtat aaggtatgtg
     1381 tatagatgaa agcatactgt ttaaacagta ttgtgttaga aaacacttga gcagaatatc
     1441 agtgtgcgtt ctaacataca ccgttaatct gcatctgtta ttacaaaggg agaaatgaag
     1501 aaaattgcct aaaattactg cttcacacag tgtttcagcc tcccctcccc accccccatc
     1561 tgtgaattga ttttgacaaa tctgtggcac taacagtttc atcaaaggac tgggtctgtg
     1621 cttgggtcat tatttcacat ctttccttag aagttcagct attgcatttg agctggacct
     1681 gatagcacac cctattggaa agaggccaga tttgacttcc gacattgatt tgacattaca
     1741 aagtgttaga atatgcttct ttatccaagc tatttctagg cagactgata cttgcttttg
     1801 gtgaattagg cagggcagtg aagtcagcta gtcatacaaa taaacagatg ggtattgtag
     1861 gctcagtttc caagtgaagg aaatcgcctg agttgaacaa gtgaaacttt gtgtcattga
     1921 ctttaaaagt ggtttctgat tagtaaagct tatgcttagc tttgcactcc cagttaatgg
     1981 catggttgtc ttgagcagag atagtataat actgcatttc cagtgggtga acacaactct
     2041 gtcgtcaact tgaatgaaac ttcaagactt aagatactat ttatttccac tgatttctgc
     2101 actggcctgt ggtgccgatt tctagtcgca tgccttacct acagcaccat gtgcattgct
     2161 gtcaaaataa agtatatttt gtcttgcatt ggtaaaaaaa aaaaaaaaaa a
//
