LOCUS       NM_025347                961 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus yippee like 3 (Ypel3), transcript variant 2, mRNA.
ACCESSION   NM_025347 XM_984414
VERSION     NM_025347.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 961)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   3  (bases 1 to 961)
  AUTHORS   Ishimura,A., Terashima,M., Tange,S. and Suzuki,T.
  TITLE     Jmjd5 functions as a regulator of p53 signaling during mouse
            embryogenesis
  JOURNAL   Cell Tissue Res 363 (3), 723-733 (2016)
   PUBMED   26334721
REFERENCE   4  (bases 1 to 961)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 961)
  AUTHORS   Berberich,S.J., Todd,A. and Tuttle,R.
  TITLE     Why YPEL3 represents a novel tumor suppressor
  JOURNAL   Front Biosci (Landmark Ed) 16 (5), 1746-1751 (2011)
   PUBMED   21196260
  REMARK    GeneRIF: Studies with mouse YPEL3, originally named small unstable
            apoptotic protein (SUAP), confirmed that the gene encodes a growth
            suppressive highly unstable protein.[review]
            Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 961)
  AUTHORS   Hosono,K., Noda,S., Shimizu,A., Nakanishi,N., Ohtsubo,M.,
            Shimizu,N. and Minoshima,S.
  TITLE     YPEL5 protein of the YPEL gene family is involved in the cell cycle
            progression by interacting with two distinct proteins RanBPM and
            RanBP10
  JOURNAL   Genomics 96 (2), 102-111 (2010)
   PUBMED   20580816
REFERENCE   7  (bases 1 to 961)
  AUTHORS   Hosono,K., Sasaki,T., Minoshima,S. and Shimizu,N.
  TITLE     Identification and characterization of a novel gene family YPEL in
            a wide spectrum of eukaryotic species
  JOURNAL   Gene 340 (1), 31-43 (2004)
   PUBMED   15556292
REFERENCE   8  (bases 1 to 961)
  AUTHORS   Baker,S.J.
  TITLE     Small unstable apoptotic protein, an apoptosis-associated protein,
            suppresses proliferation of myeloid cells
  JOURNAL   Cancer Res 63 (3), 705-712 (2003)
   PUBMED   12566317
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124505.4.
            
            On Mar 28, 2020 this sequence version replaced NM_025347.2.
            
            Transcript Variant: This variant (2), as well as variants 1 and
            3-5, encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF523353.1, BC009171.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               AC124505.4         117731-117871
            142-324             AC124505.4         118539-118721
            325-368             AC124505.4         118822-118865
            369-477             AC124505.4         119074-119182
            478-961             AC124505.4         120795-121278
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.25 cM"
     gene            1..961
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /note="yippee like 3"
                     /db_xref="GeneID:66090"
                     /db_xref="MGI:MGI:1913340"
     exon            1..141
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /inference="alignment:Splign:2.1.0"
     exon            142..324
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /inference="alignment:Splign:2.1.0"
     exon            325..368
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /inference="alignment:Splign:2.1.0"
     exon            369..477
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /inference="alignment:Splign:2.1.0"
     exon            478..961
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /inference="alignment:Splign:2.1.0"
     regulatory      943..948
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /note="hexamer: AATAAA"
     polyA_site      961
                     /gene="Ypel3"
                     /gene_synonym="0610043B10Rik; 1190001G19Rik; Suap"
                     /note="major polyA site"
ORIGIN      
        1 agccgcggca gcagctggtc tcggtgtaaa caagtcgagg cggctgtgaa ccgggccggg
       61 ggggacggcg cccatcagga gcgcccccca ctcccaggcc aggccacccc gcggaccggg
      121 ccctccacgc gcccaggcga ggcactgggc tccctctgct ccccgtgggc cgctccccgc
      181 gtggggccac tgcccttggc ccccgccatg gtgcggattt caaagcccaa gacgtttcag
      241 gcctacttgg atgactgtca ccggaggtat agctgtgccc actgccgtgc tcacctggcc
      301 aaccacgacg acctcatctc caagtccttc cagggcagtc agggacgtgc ctacctcttc
      361 aactctgtag tgaatgtggg ctgcgggcca gcagaagagc gggtgctgct gacaggtctt
      421 catgctgtcg ctgacatcca ctgtgagaac tgcaagacca ctttgggctg gaaatatgag
      481 caagcctttg agagcagcca gaagtacaaa gaggggaaat acatcattga actcaaccac
      541 atgatcaaag acaacggctg ggactgacct agctcctgcc gcatgtggct tcagcctggc
      601 ctggccgcca gggggagcca ctggtttcgc tcctcctgaa gggagctctg gaccctcagg
      661 gcccccacag gggaaggacc cagctcctgt acatacattt tattgcatgc actgtgacct
      721 tggggggaga caaagagggg gattgtaccc ccaccccctg cacctccctg cgatctggct
      781 ggcttggatc tcatttttta accccttcct gtcttgcctg tcccatagat aaggcctgtg
      841 tgctgctctc atggccctgg tgcaccacct ttctgtgaat ctctcccact ggatccctct
      901 tacctgcaac gtgtctgttc tcgttctgta gcatttgtaa ataataaaac aatggaatgg
      961 a
//
