LOCUS       NM_019661               2455 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus YKT6 v-SNARE homolog (S. cerevisiae) (Ykt6), mRNA.
ACCESSION   NM_019661
VERSION     NM_019661.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2455)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2455)
  AUTHORS   McClive,P.J., Hurley,T.M., Sarraj,M.A., van den Bergen,J.A. and
            Sinclair,A.H.
  TITLE     Subtractive hybridisation screen identifies sexually dimorphic gene
            expression in the embryonic mouse gonad
  JOURNAL   Genesis 37 (2), 84-90 (2003)
   PUBMED   14595844
REFERENCE   3  (bases 1 to 2455)
  AUTHORS   Zhang,T. and Hong,W.
  TITLE     Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and
            participates in a late stage in endoplasmic reticulum-Golgi
            transport
  JOURNAL   J Biol Chem 276 (29), 27480-27487 (2001)
   PUBMED   11323436
REFERENCE   4  (bases 1 to 2455)
  AUTHORS   McNew,J.A., Sogaard,M., Lampen,N.M., Machida,S., Ye,R.R.,
            Lacomis,L., Tempst,P., Rothman,J.E. and Sollner,T.H.
  TITLE     Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi
            transport
  JOURNAL   J Biol Chem 272 (28), 17776-17783 (1997)
   PUBMED   9211930
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645469.18.
            
            On Sep 29, 2022 this sequence version replaced NM_019661.4.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006760.1, AK147098.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AL645469.18        67742-67967
            227-309             AL645469.18        71260-71342
            310-410             AL645469.18        73151-73251
            411-515             AL645469.18        74300-74404
            516-581             AL645469.18        74656-74721
            582-683             AL645469.18        76524-76625
            684-2455            AL645469.18        77972-79743
FEATURES             Location/Qualifiers
     source          1..2455
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.89 cM"
     gene            1..2455
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /note="YKT6 v-SNARE homolog (S. cerevisiae)"
                     /db_xref="GeneID:56418"
                     /db_xref="MGI:MGI:1927550"
     exon            1..226
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..719
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /note="prenylated SNARE protein (Ykt6); YKT6 homolog"
                     /codon_start=1
                     /product="synaptobrevin homolog YKT6"
                     /protein_id="NP_062635.2"
                     /db_xref="CCDS:CCDS24410.1"
                     /db_xref="GeneID:56418"
                     /db_xref="MGI:MGI:1927550"
                     /translation="MKLYSLSVLYKGDPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTS
                     QLIVERSGKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFS
                     KQVDRIDWPVGSPATIQYTGLDDHLSKYQNPREADPMSKVQAELDETKIILHNTMESL
                     LERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM"
     exon            227..309
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            310..410
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            411..515
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            516..581
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            582..683
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            684..2455
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2431..2436
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /note="hexamer: GATAAA"
     polyA_site      2455
                     /gene="Ykt6"
                     /gene_synonym="0610042I15Rik; 1810013M05Rik"
                     /note="major polyA site"
ORIGIN      
        1 actctaggag gaagaagccg gccgggcccc gtcaggaggc ggccgccgct gttctgaggg
       61 actgtggccg cgctcctggg agcgggtctg gggctcagcc ggcggcccga aggtgcggcg
      121 ccatgaagct gtacagcctt agtgtccttt acaaaggcga tccgaaagcg gtgctgctca
      181 aggccgcgta cgacgtgtct tcctttagtt tcttccagag gtccagtgtg caggaattca
      241 tgacctttac aagtcaactg attgtggaac gctcggggaa aggcagcaga gcttctgtca
      301 aagaacaaga gtatctttgc catgtctacg tccggagcga cagtctggca ggtgtggtca
      361 ttgctgacag cgaataccct tccagagtgg ccttcacctt gctggagaag gtactagatg
      421 aattctccaa gcaggtggat agaatagact ggccagtagg atccccggct acaatccagt
      481 acacaggcct ggacgatcac cttagtaaat accagaaccc ccgagaagct gatcccatga
      541 gtaaagtgca ggccgaactg gacgagacca aaatcattct gcacaacacc atggagtctt
      601 tgttagagcg aggcgagaag cttgatgacc tggtatccaa gtcagaagtg ctgggaacac
      661 agtcgaaagc cttctataaa actgcccgga aacaaaactc ttgctgtgca atcatgtgac
      721 gtagcccacg gaggcaggcg ctggatcgtc acgtcacatc agcccctggc gacaagcagt
      781 gtctagaaga ggatctggag ccaggcagac tggctgcttt tattttgaag ttcccaagag
      841 gaatggaggg atgctttaag ggtgggaaca ttgatgttcg tatgtgtggt tgtgactttg
      901 ggaaggaatt tgaggacctc caagatgtaa tgttgggaaa atgaaaccat aaactctaag
      961 tggctcttat aggtgctgaa gggcttattc tcagctaacc ctggaaggct ctagggaggg
     1021 agtctttttc ctgatccttg gtatgactta ggattcattt gtgcattcac gatattaact
     1081 ctccatgaat ggggtggggg aggggctggg gtgatagggc tggggtgggc agagtctgaa
     1141 cactccagca ttctactacc ttgcactgtg ggggcaggga gaaagtcacc atggccagag
     1201 aaaggtagtg gtcactgggt ctcacatgtt tagcttgcct gcctggtagg actggcttct
     1261 ggcagggaca gggcctatcc taagtacctt cacccagtat cacaaagatg actttgtggg
     1321 aggtacttag aatgggctaa ggtggacagg ctgtgtaagt tttatcagct agcagactga
     1381 gtgtgggctg gaattgttct ggtgttggga gggtcagctg ggagtgtcca tctttaggga
     1441 agaagcagac acaggtgcct tcagctgtcc agtatggagg aacactcacc tggacttgca
     1501 gttggacttt gaacatcaag atcaaattag tggatgctgt cgtctcttaa agctggtttt
     1561 atttgtctct ggtccacaag agtgttttgg caactgcctg gagcttgcat gttgggacaa
     1621 atcaggacaa gtgccagcag cctgaatatt tccagtgcct acctgtggtc tgtccagttc
     1681 tggcctgtaa gcccttccct atcagagaca gttgcagagt agaggatatt gaggggttga
     1741 ggggttgatc tgagctggtg ccactgcgag cacagcctac atggtgaatc cagagtgtgc
     1801 ccggttccac atcacctctt catggtctgc tgtgcacaaa ctatatccga gagatcctgt
     1861 ctccccaaaa gccactgctg ggatgctggc ctctgatttt tgagccagcg ttgtctcact
     1921 ctgatcccta ccctgagcct gctgaactgc cctcagagtg ctcatatggg gagggggata
     1981 tctactgtgg cttccaaaag tccccactag ttggtgtacc tgtctatttc tctggatact
     2041 gctagccaaa gggctcgggc ccccccctgg actgacctgc ccatgtaatt ttcccactgc
     2101 cacagacctc tccaacccag ggcccctgga cagcacagat ccagtgtgtt gctggcactt
     2161 gaggtgtaat aaatggcctg gggtgctgcc tctttctctt gttgctctgg gggtactggg
     2221 gaggaggaga ggtgggtggc agtagaagtt tgtggggaga aggtaacctt tgcctacata
     2281 tggctgtcct acagggtctc ccttgcctgc agtgggagag ttgcccagtg gttccccatc
     2341 ccccattata ttctaatgct aaatcacttg gcaagagtgt attttaatga tgcctaattt
     2401 ctctatgttc tgtttgaagg tttctgtcca gataaaattg tcttttgaaa ttcaa
//
