LOCUS       NM_001110201            1135 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus Yip1 interacting factor homolog B (S. cerevisiae)
            (Yif1b), transcript variant 2, mRNA.
ACCESSION   NM_001110201
VERSION     NM_001110201.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Diaz,J., Gerard,X., Emerit,M.B., Areias,J., Geny,D., Degardin,J.,
            Simonutti,M., Guerquin,M.J., Collin,T., Viollet,C., Billard,J.M.,
            Metin,C., Hubert,L., Larti,F., Kahrizi,K., Jobling,R., Agolini,E.,
            Shaheen,R., Zigler,A., Rouiller-Fabre,V., Rozet,J.M., Picaud,S.,
            Novelli,A., Alameer,S., Najmabadi,H., Cohn,R., Munnich,A.,
            Barth,M., Lugli,L., Alkuraya,F.S., Blaser,S., Gashlan,M.,
            Besmond,C., Darmon,M. and Masson,J.
  TITLE     YIF1B mutations cause a post-natal neurodevelopmental syndrome
            associated with Golgi and primary cilium alterations
  JOURNAL   Brain 143 (10), 2911-2928 (2020)
   PUBMED   33103737
  REMARK    Erratum:[Brain. 2021 May 7;144(4):e40. doi: 10.1093/brain/awaa449..
            PMID: 33438001]
REFERENCE   2  (bases 1 to 1135)
  AUTHORS   Alterio,J., Masson,J., Diaz,J., Chachlaki,K., Salman,H., Areias,J.,
            Al Awabdh,S., Emerit,M.B. and Darmon,M.
  TITLE     Yif1B Is Involved in the Anterograde Traffic Pathway and the Golgi
            Architecture
  JOURNAL   Traffic 16 (9), 978-993 (2015)
   PUBMED   26077767
  REMARK    GeneRIF: if1B depletion disorganizes Golgi architecture and
            anterograde traffic.
REFERENCE   3  (bases 1 to 1135)
  AUTHORS   Barone,V., Mazzoli,E., Kunic,J., Rossi,D., Tronnolone,S. and
            Sorrentino,V.
  TITLE     Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi
            compartments and is not required for maintenance of the Golgi
            structure in skeletal muscle
  JOURNAL   Histochem Cell Biol 143 (3), 235-243 (2015)
   PUBMED   25208654
REFERENCE   4  (bases 1 to 1135)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AV482229.1, BU953116.1, BC109331.2 and AW743704.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC109331.2, CA979649.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 AV482229.1         3-8
            7-695               BU953116.1         4-692
            696-1044            BC109331.2         675-1023
            1045-1135           AW743704.1         1-91                c
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.94 cM"
     gene            1..1135
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /note="Yip1 interacting factor homolog B (S. cerevisiae)"
                     /db_xref="GeneID:77254"
                     /db_xref="MGI:MGI:1924504"
     exon            1..114
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..995
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /note="isoform 2 is encoded by transcript variant 2;
                     protein YIF1B; YIP1-interacting factor homolog B"
                     /codon_start=1
                     /product="protein YIF1B isoform 2"
                     /protein_id="NP_001103671.1"
                     /db_xref="CCDS:CCDS52171.1"
                     /db_xref="GeneID:77254"
                     /db_xref="MGI:MGI:1924504"
                     /translation="MHATGLAAPAGTPRLPSKRRVPVSQPGMADPHQFFDDTSSAPSR
                     GYGGQPSPGGLGYPPSSSDAAFLAAPMSNMAMVYGSSLAAQGKELVDKNIDRFIPVSK
                     LKYYFAVDTVYVGKKLGLLVFPYLHQDWEVQYQQDTPVAPRFDINAPDLYIPAMAFIT
                     YILVAGLALGTQDRFSPDLLGLQASSALAWLTLEVVAILLSLYLVTVNTDLTTIDLVA
                     FLGYKYVGMIGGVLTGLLFGKIGYYLVLAWCCVSIFVFMIRTLRLKILAQAAAEGVPV
                     RGARNQLRMYLTMAVAAAQPVLMYWLTFHLVR"
     exon            115..347
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            348..452
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            453..531
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            532..589
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            590..745
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            746..839
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     exon            840..1135
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1113..1118
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /note="hexamer: AATAAA"
     polyA_site      1132
                     /gene="Yif1b"
                     /gene_synonym="9430029K10Rik; Yip1b"
                     /note="major polyA site"
ORIGIN      
        1 ggctacggga accgggcggg cccattccaa actgcggctg tggcgttctc ggccgtggca
       61 tctaaagcat gcacgcgaca ggtttggcgg cgccggcggg gacgccccgg ctgccctcaa
      121 agcggagggt cccagtgtcc caaccaggca tggctgatcc ccaccagttt tttgatgaca
      181 cgagttctgc cccaagccgg ggctatggag gccagccgtc acctggtggt ctgggttacc
      241 ccccctcttc atccgacgca gccttcctgg ctgcccctat gtccaacatg gcgatggtct
      301 acgggagcag cctggccgct cagggcaagg agctggtaga taagaatatc gaccgcttca
      361 tccccgtcag caagctcaag tattactttg cagtggacac ggtgtatgtg ggcaagaagc
      421 ttgggctgct ggtctttccc taccttcacc aggactggga ggtacagtac caacaggaca
      481 ccccagtggc cccccgcttc gacatcaatg ctccagacct ctacattcca gccatggctt
      541 tcatcaccta catcttggtg gccggccttg cactggggac ccaggacagg ttctccccag
      601 acctcctggg actgcaggcg agctcagctc tggcctggct gactctggaa gtcgtagcaa
      661 tcctgctcag tctctacctg gtcactgtca acaccgacct caccaccatt gacctggtgg
      721 ccttcttggg ctacaaatat gtggggatga ttggcggcgt cctcacgggt ctgctctttg
      781 gaaagatcgg ctactacctg gtgcttgcct ggtgctgtgt gtccatcttt gtattcatga
      841 tccggacact gcggctcaag atcctggccc aggcagcggc cgaaggagtg ccagtgcgtg
      901 gggcgcggaa ccagctgcgc atgtacctga ctatggcagt ggcagctgcg cagccggtac
      961 tcatgtactg gctcaccttc caccttgtac ggtgagctgc ggcctggcct ccagctccca
     1021 cactcatctc gcttgaccag ggctcccgcc ctccaggccc gcgccctcct tcctagccaa
     1081 ggtgctcatg tcgcctactg cacacccgca acaataaacc tgatgggctc ggcgc
//
