LOCUS       NM_139117               1862 bp    mRNA    linear   ROD 28-AUG-2024
DEFINITION  Mus musculus Y box protein 3 (Ybx3), transcript variant 1, mRNA.
ACCESSION   NM_139117
VERSION     NM_139117.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1862)
  AUTHORS   Droste,P., Boor,P. and Bulow,R.D.
  TITLE     DNA-binding protein-A: a multitool in tubular epithelial cells
  JOURNAL   Kidney Int 106 (2), 185-188 (2024)
   PUBMED   39032963
  REMARK    GeneRIF: DNA-binding protein-A: a multitool in tubular epithelial
            cells.
REFERENCE   2  (bases 1 to 1862)
  AUTHORS   Reichardt,C., Brandt,S., Bernhardt,A., Krause,A., Lindquist,J.A.,
            Weinert,S., Geffers,R., Franz,T., Kahlfuss,S., Dudeck,A.,
            Mathew,A., Rana,R., Isermann,B. and Mertens,P.R.
  TITLE     DNA-binding protein-A promotes kidney ischemia/reperfusion injury
            and participates in mitochondrial function
  JOURNAL   Kidney Int 106 (2), 241-257 (2024)
   PUBMED   38821446
  REMARK    GeneRIF: DNA-binding protein-A promotes kidney ischemia/reperfusion
            injury and participates in mitochondrial function.
REFERENCE   3  (bases 1 to 1862)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1862)
  AUTHORS   Awad,S., Skipper,W., Vostrejs,W., Ozorowski,K., Min,K., Pfuhler,L.,
            Mehta,D. and Cooke,A.
  TITLE     The YBX3 RNA-binding protein posttranscriptionally controls SLC1A5
            mRNA in proliferating and differentiating skeletal muscle cells
  JOURNAL   J Biol Chem 300 (2), 105602 (2024)
   PUBMED   38159852
  REMARK    GeneRIF: The YBX3 RNA-binding protein posttranscriptionally
            controls SLC1A5 mRNA in proliferating and differentiating skeletal
            muscle cells.
REFERENCE   5  (bases 1 to 1862)
  AUTHORS   Lindquist,J.A., Bernhardt,A., Reichardt,C., Sauter,E., Brandt,S.,
            Rana,R., Lindenmeyer,M.T., Philipsen,L., Isermann,B., Zhu,C. and
            Mertens,P.R.
  TITLE     Cold Shock Domain Protein DbpA Orchestrates Tubular Cell Damage and
            Interstitial Fibrosis in Inflammatory Kidney Disease
  JOURNAL   Cells 12 (10), 1426 (2023)
   PUBMED   37408260
  REMARK    GeneRIF: Cold Shock Domain Protein DbpA Orchestrates Tubular Cell
            Damage and Interstitial Fibrosis in Inflammatory Kidney Disease.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1862)
  AUTHORS   Mastrangelo,M.A. and Kleene,K.C.
  TITLE     Developmental expression of Y-box protein 1 mRNA and alternatively
            spliced Y-box protein 3 mRNAs in spermatogenic cells in mice
  JOURNAL   Mol Hum Reprod 6 (9), 779-788 (2000)
   PUBMED   10956549
REFERENCE   7  (bases 1 to 1862)
  AUTHORS   Davies,H.G., Giorgini,F., Fajardo,M.A. and Braun,R.E.
  TITLE     A sequence-specific RNA binding complex expressed in murine germ
            cells contains MSY2 and MSY4
  JOURNAL   Dev Biol 221 (1), 87-100 (2000)
   PUBMED   10772793
REFERENCE   8  (bases 1 to 1862)
  AUTHORS   Funke,B., Zuleger,B., Benavente,R., Schuster,T., Goller,M.,
            Stevenin,J. and Horak,I.
  TITLE     The mouse poly(C)-binding protein exists in multiple isoforms and
            interacts with several RNA-binding proteins
  JOURNAL   Nucleic Acids Res 24 (19), 3821-3828 (1996)
   PUBMED   8871564
REFERENCE   9  (bases 1 to 1862)
  AUTHORS   Duh,J.L., Zhu,H., Shertzer,H.G., Nebert,D.W. and Puga,A.
  TITLE     The Y-box motif mediates redox-dependent transcriptional activation
            in mouse cells
  JOURNAL   J Biol Chem 270 (51), 30499-30507 (1995)
   PUBMED   8530481
REFERENCE   10 (bases 1 to 1862)
  AUTHORS   Sakura,H., Maekawa,T., Imamoto,F., Yasuda,K. and Ishii,S.
  TITLE     Two human genes isolated by a novel method encode DNA-binding
            proteins containing a common region of homology
  JOURNAL   Gene 73 (2), 499-507 (1988)
   PUBMED   2977358
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC027785.1 and BC048242.1.
            
            On May 6, 2004 this sequence version replaced NM_139117.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the long isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048242.1, AF246224.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-744               BC027785.1         12-755
            745-1862            BC048242.1         733-1850
FEATURES             Location/Qualifiers
     source          1..1862
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 63.44 cM"
     gene            1..1862
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /note="Y box protein 3"
                     /db_xref="GeneID:56449"
                     /db_xref="MGI:MGI:2137670"
     exon            1..433
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             196..1281
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /note="long isoform is encoded by transcript variant 1;
                     cold shock domain-containing protein A; cold shock domain
                     protein A; Y-box-binding protein 3; DNA-binding protein A"
                     /codon_start=1
                     /product="Y-box-binding protein 3 long isoform"
                     /protein_id="NP_620817.2"
                     /db_xref="CCDS:CCDS20606.1"
                     /db_xref="GeneID:56449"
                     /db_xref="MGI:MGI:2137670"
                     /translation="MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPA
                     PAALLAGSPGGDAAPGPAPASSAPAGGEDAEKKVLATKVLGTVKWFNVRNGYGFINRN
                     DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGS
                     RYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRP
                     QYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGTQLQAHRNPT
                     YRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRSRPLNAV
                     SQDGKETKAGEAPTENPAPATEQSSAE"
     exon            434..497
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            498..531
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            532..621
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            622..744
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            745..951
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1043
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1215
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1314
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1862
                     /gene="Ybx3"
                     /gene_synonym="Csda; dbpA; Dpba; MSY3; MSY4; oxyR; Yb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcggggcc atcttcgggg ccgggagatc cagcgagacc gcgagcgcgc gcgtccccag
       61 ccctcgagcc gccgcccgcc gccgcgccgc gcgatccgca ccggcctccc cgagagcgag
      121 ccggacgccg cgactgccac cgcgctaacc gccgccaacc gccaccgagg tgcccggaga
      181 gagcggagag gcggcatgag cgaggcgggc gaggccacca ccggcggcac cacgctcccg
      241 caggccgcgg ccgacgcgcc cgccgcggcg cccccggacc ccgcgcctaa gagcccggcg
      301 gccagcggcg cgccccaggc cccggcgccc gccgcgctgc tcgcggggag ccccggcgga
      361 gacgcagccc ccgggcccgc cccggcctca tcagcccccg cgggcggcga ggacgcggag
      421 aagaaagttc tcgccaccaa agtccttggc actgtcaaat ggttcaacgt cagaaatgga
      481 tatggattta taaaccgaaa tgacaccaaa gaagatgtgt ttgtacacca gacggccatc
      541 aagaaaaaca acccacgcaa gtatctgcgc agtgtggggg atggagaaac tgtagagttt
      601 gatgtagttg aaggagaaaa gggtgctgaa gcagcaaacg tgactggccc agatggagtt
      661 cctgtagaag ggagtcgcta tgctgctgac cggcgccggt acagacgcgg ctactatggc
      721 aggcgccgtg gacctccccg taattacgct ggggaggagg aggaggaagg gagcggcagc
      781 agtgaaggat ttgagccccc tgccgcagat gggcagttct ctggggccag gaatcagctg
      841 cgccgccccc agtatcgccc tccataccgg cagcggcgtt tcccgcctta ccacgtggga
      901 cagacctttg accgtcgctc acgggtcttt ccccatccca acagaatgca ggctggtgag
      961 attggggaga tgaaggatgg agtccccgag ggaacacagc tccaggctca tcggaatccg
     1021 acttaccgcc cgaggttccg caggggacct gctcgcccac gacctgcccc tgctattgga
     1081 gaggctgaag acaaagaaaa ccagcaagcg gctaatggtc caaaccagcc gtctgcccgc
     1141 cgtggattcc gacgtcccta caactatagg cgccgttccc gtcccctcaa cgctgtttca
     1201 caagatggca aagagaccaa ggcaggtgaa gcaccaactg agaaccccgc tccagctacc
     1261 gaacagagca gtgccgagtg accctggctc ccaggcaccg taaccaccag cagggtgacc
     1321 taaagaatta atgaccattc aaaaacaagg caaaaaagca cacccacgac cttaccaaca
     1381 ccaaagaaac atctaagcaa taaaatggaa gactaaccaa gaattggaca ttagaatgtt
     1441 tactgctatt ctctacgaaa ctaacaacta caaagggaac gagccagcaa gtgtccatca
     1501 agctgtatcc cgggaacctg cacaggcgca ggagagcagc ctccccagtt tcagcaacct
     1561 agtgctttct atttttttcc tggtttttac tgttttggta atatgaatta aaagaagaaa
     1621 tattaatacc acatggggat tgccccaacc aaagaaatct gaaatatata gtaaatgctc
     1681 tttttccttt gttgttcatt ttggatgctg gtgctaaact tccaagtgtc atgatttaag
     1741 aagaaatttt atgcccttat ttattcctag gatgagggga gaacgttttt gctttctcac
     1801 atagctctct ctgaaatgtg cagtaacaag ttcctcaaaa ataaaatttt taccttcaaa
     1861 gg
//
