LOCUS       NM_016875               1642 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus Y box protein 2 (Ybx2), transcript variant 1, mRNA.
ACCESSION   NM_016875 XM_909121
VERSION     NM_016875.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Yao,X., Wang,C., Yu,W., Sun,L., Lv,Z., Xie,X., Tian,S., Yan,L.,
            Li,L. and Liu,J.
  TITLE     BCAS2 regulates oocyte meiotic prophase I by participating in mRNA
            alternative splicing
  JOURNAL   FASEB J 38 (1), e23361 (2024)
   PUBMED   38085152
REFERENCE   2  (bases 1 to 1642)
  AUTHORS   Ding,Y., He,Z., Sha,Y., Kee,K. and Li,L.
  TITLE     Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics
            and leads to subfertility
  JOURNAL   Development 150 (23) (2023)
   PUBMED   38088064
REFERENCE   3  (bases 1 to 1642)
  AUTHORS   Huang,T., Wu,X., Wang,S., Bao,Z., Wan,Y., Wang,Z., Li,M., Yu,X.,
            Lv,Y., Liu,Z., Chen,X., Chan,W.Y., Gao,F., Lu,G., Chen,Z.J. and
            Liu,H.
  TITLE     SPIDR is required for homologous recombination during mammalian
            meiosis
  JOURNAL   Nucleic Acids Res 51 (8), 3855-3868 (2023)
   PUBMED   36938872
REFERENCE   4  (bases 1 to 1642)
  AUTHORS   Guan,Y., Lin,H., Leu,N.A., Ruthel,G., Fuchs,S.Y., Busino,L., Luo,M.
            and Wang,P.J.
  TITLE     SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early
            meiotic recombination
  JOURNAL   Nucleic Acids Res 50 (9), 5129-5144 (2022)
   PUBMED   35489071
REFERENCE   5  (bases 1 to 1642)
  AUTHORS   He,Y., Chen,Q., Dai,J., Cui,Y., Zhang,C., Wen,X., Li,J., Xiao,Y.,
            Peng,X., Liu,M., Shen,B., Sha,J., Hu,Z., Li,J. and Shu,W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   6  (bases 1 to 1642)
  AUTHORS   Soyal,S.M., Amleh,A. and Dean,J.
  TITLE     FIGalpha, a germ cell-specific transcription factor required for
            ovarian follicle formation
  JOURNAL   Development 127 (21), 4645-4654 (2000)
   PUBMED   11023867
REFERENCE   7  (bases 1 to 1642)
  AUTHORS   Davies,H.G., Giorgini,F., Fajardo,M.A. and Braun,R.E.
  TITLE     A sequence-specific RNA binding complex expressed in murine germ
            cells contains MSY2 and MSY4
  JOURNAL   Dev Biol 221 (1), 87-100 (2000)
   PUBMED   10772793
REFERENCE   8  (bases 1 to 1642)
  AUTHORS   Herbert,T.P. and Hecht,N.B.
  TITLE     The mouse Y-box protein, MSY2, is associated with a kinase on
            non-polysomal mouse testicular mRNAs
  JOURNAL   Nucleic Acids Res 27 (7), 1747-1753 (1999)
   PUBMED   10076007
REFERENCE   9  (bases 1 to 1642)
  AUTHORS   Gu,W., Tekur,S., Reinbold,R., Eppig,J.J., Choi,Y.C., Zheng,J.Z.,
            Murray,M.T. and Hecht,N.B.
  TITLE     Mammalian male and female germ cells express a germ cell-specific
            Y-Box protein, MSY2
  JOURNAL   Biol Reprod 59 (5), 1266-1274 (1998)
   PUBMED   9780336
REFERENCE   10 (bases 1 to 1642)
  AUTHORS   Funke,B., Zuleger,B., Benavente,R., Schuster,T., Goller,M.,
            Stevenin,J. and Horak,I.
  TITLE     The mouse poly(C)-binding protein exists in multiple isoforms and
            interacts with several RNA-binding proteins
  JOURNAL   Nucleic Acids Res 24 (19), 3821-3828 (1996)
   PUBMED   8871564
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596185.12.
            
            On Apr 12, 2022 this sequence version replaced NM_016875.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF073954.1, BC141112.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-423               AL596185.12        47471-47893
            424-487             AL596185.12        48542-48605
            488-521             AL596185.12        49987-50020
            522-611             AL596185.12        50883-50972
            612-896             AL596185.12        51519-51803
            897-1000            AL596185.12        51973-52076
            1001-1178           AL596185.12        52235-52412
            1179-1263           AL596185.12        52691-52775
            1264-1642           AL596185.12        52871-53249
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.93 cM"
     gene            1..1642
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /note="Y box protein 2"
                     /db_xref="GeneID:53422"
                     /db_xref="MGI:MGI:1096372"
     exon            1..423
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1229
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /note="isoform 1 is encoded by transcript variant 1; Y-box
                     protein MSY2; Y-box-binding protein 2; germ cell-specific
                     Y-box-binding protein"
                     /codon_start=1
                     /product="Y-box-binding protein 2 isoform 1"
                     /protein_id="NP_058571.2"
                     /db_xref="CCDS:CCDS36200.1"
                     /db_xref="GeneID:53422"
                     /db_xref="MGI:MGI:1096372"
                     /translation="MSEAEASVVATAAPAATVPATAAGVVAVVVPVPAGEPQKAGGGA
                     GGGGGAASGPAAGTPSAPGPRTPGNQATAASGTPAPPARSQADKPVLAIQVLGTVKWF
                     NVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEAAN
                     VTGPGGVPVKGSRYAPNRRRFRRFIPRPRPAAPPPMVAEAPSGGTEPGSEGERAEDSG
                     QRPRRRRPPPFFYRRRFVRGPRPPNQQQPIEGSDGVEPKETAPLEGDQQQGDERVPPP
                     RFRPRYRRPFRPRPPQQPTTEGGDGETKPSQGPTDGSRPEPQRPRNRPYFQRRRQQPP
                     GPRQPIAAETSAPINSGDPPTTILE"
     exon            424..487
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            488..521
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            522..611
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            612..896
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1000
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1178
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1263
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1642
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1615..1620
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /note="hexamer: AGTAAA"
     polyA_site      1642
                     /gene="Ybx2"
                     /gene_synonym="Msy2"
                     /note="major polyA site"
ORIGIN      
        1 agggcccgcg gcaggcgtgc gggcgaggct cggggcgcga ggaccgagcc gggtggccgg
       61 tccgcgagcc ggggggaggg gccggggtgg tggtggtggc agcggcggag gaggcggtgg
      121 cggcgggggc cggtactgga cccggcggga tgagcgaggc ggaggcgtca gtggtggcga
      181 cagcggcccc cgcggcgacg gtgcccgcga cggcggcggg ggtggtagcg gtggtggtac
      241 cggtgcccgc gggagagccg cagaaagcag gcggcggggc gggcggcggg ggcggagccg
      301 cctctggccc cgctgctggg accccctcag cgcccggccc tcgcacccct ggcaaccagg
      361 cgacggcggc ctcggggact cccgcgcccc cggcccggag tcaggcggac aagccggtgc
      421 tggcaatcca agtcctgggc acagtcaaat ggttcaacgt ccggaatggt tacggattca
      481 tcaacaggaa tgacaccaag gaggatgtct ttgttcacca gacagctatt aagagaaaca
      541 accccaggaa gtttctgcgg agtgttggag atggggagac tgtggagttt gatgtcgtgg
      601 aaggagagaa gggtgcagaa gctgctaatg tcactgggcc tgggggggta ccagtgaagg
      661 gcagccgcta tgcccctaat cgacgtaggt tccggaggtt cattcctcgg cctcgcccag
      721 ctgccccacc acctatggtg gcagaggctc cctcaggtgg gacagaacct ggcagcgaag
      781 gggagcgggc agaggactcg gggcagcgac ctagacgacg gcgcccacca cccttcttct
      841 atcgaaggcg gtttgtgcga ggccctcggc cccccaacca gcaacagccc atagagggct
      901 ctgatggggt agaacccaag gagacagcac cattggaggg tgatcaacag cagggagatg
      961 aacgggtgcc cccacccaga ttccggccca ggtaccgaag gcctttccgc cccaggccac
     1021 cccaacagcc taccacagaa ggtggggatg gagagaccaa gcccagccaa ggccccactg
     1081 atggctcccg gcctgagccc cagcgtccac gaaaccgtcc ctacttccag cggcgtcggc
     1141 agcagccccc tggcccccgg cagcctatag ccgcagagac ctccgcgcct atcaacagtg
     1201 gggacccccc caccaccata ctggagtgat tccaactcag aggacaccca gagctaccat
     1261 ctggtatctg ccagtttcca actgactcta cccagcatcc ccctccccac tttcccataa
     1321 ttcatgacat caaaacatcg gcttttccct tgagactcag gagggccaaa gcaccagcct
     1381 ttggcttttt tctctttttt ttccctctcc cctagcatgg gttgaaggaa gggatccatc
     1441 cttattgttc cgaggcatca cctccctccc tagtcaggct gagaaggaac cagccagctc
     1501 atacctcctc ctgattgttt ttcttcccca cccatttatt ttttgtttcc cttcgacctc
     1561 cccccaacac ctctgaagcc attttatgaa ctgtcatgtg ccacctgagc ctccagtaaa
     1621 aacaaaagca ggctttcttg tt
//
