LOCUS       NM_011732               2191 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus Y box protein 1 (Ybx1), mRNA.
ACCESSION   NM_011732 XM_906453
VERSION     NM_011732.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Cai,S. and Yin,N.
  TITLE     Single-cell transcriptome and chromatin accessibility mapping of
            upper lip and primary palate fusion
  JOURNAL   J Cell Mol Med 28 (19), e70128 (2024)
   PUBMED   39392189
REFERENCE   2  (bases 1 to 2191)
  AUTHORS   Wei,H., Zhu,Z., Xu,Y., Lin,L., Chen,Q., Liu,Y., Li,Y. and Zhu,X.
  TITLE     Microglia-derived exosomes selective sorted by YB-1 alleviate nerve
            damage and cognitive outcome in Alzheimer's disease
  JOURNAL   J Transl Med 22 (1), 466 (2024)
   PUBMED   38755651
  REMARK    GeneRIF: Microglia-derived exosomes selective sorted by YB-1
            alleviate nerve damage and cognitive outcome in Alzheimer's
            disease.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2191)
  AUTHORS   Li,Y.J., Guo,Q., Ye,M.S., Cai,G., Xiao,W.F., Deng,S. and Xiao,Y.
  TITLE     YBX1 promotes type H vessel-dependent bone formation in an
            m5C-dependent manner
  JOURNAL   JCI Insight 9 (4), e172345 (2024)
   PUBMED   38385749
  REMARK    GeneRIF: YBX1 promotes type H vessel-dependent bone formation in an
            m5C-dependent manner.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2191)
  AUTHORS   Zhou,R., Huang,Y., Feng,X., Zhou,R., Wang,L., Xie,G., Xiao,Y. and
            Zhou,H.
  TITLE     Decreased YB-1 expression denervates brown adipose tissue and
            contributes to age-related metabolic dysfunction
  JOURNAL   Cell Prolif 57 (1), e13520 (2024)
   PUBMED   37321837
  REMARK    GeneRIF: Decreased YB-1 expression denervates brown adipose tissue
            and contributes to age-related metabolic dysfunction.
REFERENCE   5  (bases 1 to 2191)
  AUTHORS   Li,H., Zhang,D., Fu,Q., Wang,S., Wang,Z., Zhang,X., Chen,X.,
            Zhu,X., An,N., Chen,Y., Zhou,L., Lu,D. and Zhao,N.
  TITLE     YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia
  JOURNAL   Blood Adv 7 (17), 4874-4885 (2023)
   PUBMED   37339496
  REMARK    GeneRIF: YBX1 as an oncogenic factor in T-cell acute lymphoblastic
            leukemia.
REFERENCE   6  (bases 1 to 2191)
  AUTHORS   Nikolajczyk,B.S., Murray,M.T. and Hecht,N.B.
  TITLE     A mouse homologue of the Xenopus germ cell-specific ribonucleic
            acid/deoxyribonucleic acid-binding proteins p54/p56 interacts with
            the protamine 2 promoter
  JOURNAL   Biol Reprod 52 (3), 524-530 (1995)
   PUBMED   7756448
REFERENCE   7  (bases 1 to 2191)
  AUTHORS   Wolffe,A.P.
  TITLE     Structural and functional properties of the evolutionarily ancient
            Y-box family of nucleic acid binding proteins
  JOURNAL   Bioessays 16 (4), 245-251 (1994)
   PUBMED   8031301
  REMARK    Review article
REFERENCE   8  (bases 1 to 2191)
  AUTHORS   Wolffe,A.P., Tafuri,S., Ranjan,M. and Familari,M.
  TITLE     The Y-box factors: a family of nucleic acid binding proteins
            conserved from Escherichia coli to man
  JOURNAL   New Biol 4 (4), 290-298 (1992)
   PUBMED   1622927
  REMARK    Review article
REFERENCE   9  (bases 1 to 2191)
  AUTHORS   Gai,X.X., Lipson,K.E. and Prystowsky,M.B.
  TITLE     Unusual DNA binding characteristics of an in vitro translation
            product of the CCAAT binding protein mYB-1
  JOURNAL   Nucleic Acids Res 20 (3), 601-606 (1992)
   PUBMED   1741293
REFERENCE   10 (bases 1 to 2191)
  AUTHORS   Shaughnessy,M. and Wistow,G.
  TITLE     Absence of MHC gene expression in lens and cloning of dbpB/YB-1, a
            DNA-binding protein expressed in mouse lens
  JOURNAL   Curr Eye Res 11 (2), 175-181 (1992)
   PUBMED   1572207
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU512458.1, AK150821.1, BX470153.3 and BG066506.2.
            
            On Aug 26, 2006 this sequence version replaced NM_011732.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150821.1, BC061634.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                BU512458.1         5-22
            19-1532             AK150821.1         7-1520
            1533-1712           BX470153.3         22599-22778         c
            1713-2191           BG066506.2         1-479               c
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4"
     gene            1..2191
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /note="Y box protein 1"
                     /db_xref="GeneID:22608"
                     /db_xref="MGI:MGI:99146"
     exon            1..310
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..1119
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /note="nuclease-sensitive element-binding protein 1;
                     CBF-A; EFI-A; DNA-binding protein B; Y-box transcription
                     factor; enhancer factor I subunit A; CCAAT-binding
                     transcription factor I subunit A"
                     /codon_start=1
                     /product="Y-box-binding protein 1"
                     /protein_id="NP_035862.2"
                     /db_xref="CCDS:CCDS18579.1"
                     /db_xref="GeneID:22608"
                     /db_xref="MGI:MGI:99146"
                     /translation="MSSEAETQQPPAAPAAALSAADTKPGSTGSGAGSGGPGGLTSAA
                     PAGGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVG
                     DGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNY
                     QNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYARRPQYSNPPVQGEVMEG
                     ADNQGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQ
                     RRYRRNFNYRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGGAE"
     exon            311..374
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            375..408
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            409..498
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            499..801
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            802..884
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1150
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..2191
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1517..1522
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /note="hexamer: AATAAA"
     regulatory      1533..1538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /note="hexamer: AATAAT"
     polyA_site      1537
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
                     /note="major polyA site"
     polyA_site      1555
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
     polyA_site      2171
                     /gene="Ybx1"
                     /gene_synonym="1700102N10Rik; dbpB; EF1A; MSY1; mYB-1a;
                     Nsep1; YB-1"
ORIGIN      
        1 cgccattctc gctagttcga tcggtagcgg gagcggagag cggaccccag agagccctga
       61 gagccccacc gccgccgccg gcctagtcac catcacaccc gggaggagcc gcagccgtcg
      121 ccgccggccc cagtcaccat caccgcaacc atgagcagcg aggccgagac ccagcagccg
      181 cccgccgccc ccgccgccgc cctcagcgcc gccgacacca agcccggctc cacgggcagc
      241 ggcgcgggta gtggcggccc gggtggcctc acatcggcgg cgcccgccgg cggggacaag
      301 aaggtcatcg caacgaaggt tttgggaaca gtcaaatggt tcaatgtaag gaacggatac
      361 ggtttcatca acaggaatga caccaaggaa gacgtatttg tacaccagac tgccataaag
      421 aagaataacc ccaggaagta ccttcgcagt gtaggcgatg gagagactgt ggagtttgat
      481 gttgttgaag gagaaaaggg tgcggaggca gcaaatgtta caggccctgg tggagttcca
      541 gttcaaggca gtaaatacgc agcagaccgt aaccattata gacgctatcc acgtcgtagg
      601 ggtcctccac gcaattacca gcaaaattac cagaatagtg agagtgggga aaagaacgag
      661 ggatcggaaa gcgctcctga aggccaggcc caacaacgcc ggccctatcg caggcgaagg
      721 ttcccacctt actacatgcg gagaccctat gcgcgtcgac cacagtattc caacccccct
      781 gtgcaaggag aagtgatgga gggtgctgac aaccagggtg caggagagca aggtagacca
      841 gtgagacaga atatgtatcg gggttacaga ccacgattcc gaaggggccc tcctcgccaa
      901 agacagccta gagaggatgg caatgaagag gacaaagaaa atcaaggaga tgagacccaa
      961 ggtcagcagc cacctcaacg tcggtatcgc cgaaacttca attaccgacg cagacgccca
     1021 gagaacccta aaccacaaga tggcaaagag acaaaagcag ccgatccacc agctgagaat
     1081 tcgtccgctc ccgaggctga gcagggcggg gctgagtaaa tgccggctta ccatctctac
     1141 catcatccgg tttggtcatc caacaagaag aaatgaatat gaaattccag caataagaaa
     1201 tgaacaaaga ttggagctga agaccttaag tgcttgcttt ttgccctctg accagataac
     1261 attagaacta tctgcattat ctatgcagca tggggttttt attattttta cctaaagatg
     1321 tctctttttg gtaatgacaa acgtgttttt taagaaaaaa aaaaaaaagg cctggttttt
     1381 ctcaatacac ctttaacggt ttttaaattg tttcatatct ggtcaagttg agatttttaa
     1441 gaacttcatt tttaatttgt aataaagttt acaacttgat tttttcaaaa aagtcaacaa
     1501 actgcaagca cctgttaata aaggtcttaa ataataatgt ctagttttgt cataattgag
     1561 tactctctcc cacttttaga ataacaggta acaccagcag taagcagtct gtcaggagtg
     1621 ctgtgaggca tcagctgtag ccacgtgagt ggggtagaga agctttgtgg ggccgggcta
     1681 gtctggggtg tttccctcta gagaagctcc agggcgagcg cactggcatc gcactaaaga
     1741 actgctgctg agtggggact aatggctgct agttgtccgc caagtccatc aactttttag
     1801 gccaattctt tgtagtagaa actaatagga attgatgaaa gacttcagca gccctattaa
     1861 cataaacaca cagagacatg ttagtgttag ctcataccag tcatggtgac tgctgtaaat
     1921 actctgctgt caagagcata gtgaaagaat tcctgggtaa gattcacagg tgtgagttta
     1981 ccgataacag acagtgttgg ttaaaaccta atgttggggg ccgggtgtgg tggcgcacgc
     2041 ctttaatccc agcactcggg aggtagaggc aggcggattt ctaaattcga ggccagcctg
     2101 gtctacagag tgagttccag gacagccaga gctacacaga gaaaccctgt ctcaaaaaat
     2161 aaataaataa ataaataaat aaataaaacc t
//
