LOCUS       NM_172550               4538 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus ybeY metallopeptidase (Ybey), mRNA.
ACCESSION   NM_172550
VERSION     NM_172550.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4538)
  AUTHORS   Endoh-Yamagami,S., Karkar,K.M., May,S.R., Cobos,I., Thwin,M.T.,
            Long,J.E., Ashique,A.M., Zarbalis,K., Rubenstein,J.L. and
            Peterson,A.S.
  TITLE     A mutation in the pericentrin gene causes abnormal interneuron
            migration to the olfactory bulb in mice
  JOURNAL   Dev Biol 340 (1), 41-53 (2010)
   PUBMED   20096683
REFERENCE   2  (bases 1 to 4538)
  AUTHORS   Willnow,T., Antignac,C., Brandli,A., Christensen,E., Cox,R.,
            Davidson,D., Davies,J., Devuyst,O., Eichele,G., Hastie,N.,
            Verroust,P., Schedl,A. and Meij,I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
REFERENCE   3  (bases 1 to 4538)
  AUTHORS   Reymond,A., Marigo,V., Yaylaoglu,M.B., Leoni,A., Ucla,C.,
            Scamuffa,N., Caccioppoli,C., Dermitzakis,E.T., Lyle,R., Banfi,S.,
            Eichele,G., Antonarakis,S.E. and Ballabio,A.
  TITLE     Human chromosome 21 gene expression atlas in the mouse
  JOURNAL   Nature 420 (6915), 582-586 (2002)
   PUBMED   12466854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC057308.1 and AK136543.1.
            
            On Sep 1, 2006 this sequence version replaced NM_172550.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057308.1, AK037727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-251               BC057308.1         1-251
            252-2903            AK136543.1         3-2654
            2904-4538           BC057308.1         2904-4538
FEATURES             Location/Qualifiers
     source          1..4538
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 38.85 cM"
     gene            1..4538
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="ybeY metallopeptidase"
                     /db_xref="GeneID:216119"
                     /db_xref="MGI:MGI:2656825"
     exon            1..341
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /inference="alignment:Splign:2.1.0"
     exon            342..571
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /inference="alignment:Splign:2.1.0"
     CDS             362..856
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="putative metalloprotease C21orf57 homolog; rRNA
                     maturation factor homolog; putative ribonuclease"
                     /codon_start=1
                     /product="endoribonuclease YbeY"
                     /protein_id="NP_766138.3"
                     /db_xref="CCDS:CCDS23946.1"
                     /db_xref="GeneID:216119"
                     /db_xref="MGI:MGI:2656825"
                     /translation="MSLVIKNLQRVVPIRRVPLRRKMDLVRSILGVKKFDLGIICVDN
                     KTIQNINRIYRNKNVPTDVLSFSFHENLKAGEFPQPHSPDDYNLGDIFLGVEYILQHC
                     RESEDYCDVLTVTATHGLCHLLGFTHSSKAEWQKMYNQEKLVLEELSRYTGARLQPLS
                     RGLY"
     exon            572..700
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /inference="alignment:Splign:2.1.0"
     exon            701..769
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /inference="alignment:Splign:2.1.0"
     exon            770..4522
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2884..2889
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="hexamer: AATAAA"
     polyA_site      2904
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="major polyA site"
     regulatory      3931..3936
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="hexamer: TATAAA"
     polyA_site      3951
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
     regulatory      4077..4082
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="hexamer: AATAAA"
     polyA_site      4083
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
     polyA_site      4115
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
     regulatory      4495..4500
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
                     /note="hexamer: ATTAAA"
     polyA_site      4522
                     /gene="Ybey"
                     /gene_synonym="1110068N23Rik; A130042E20Rik; C21orf57;
                     ORF57; ORF66"
ORIGIN      
        1 gttaacagac gccttcgagc gaagactagt gaaggccttc agcaactcgg caaagacaca
       61 agggacagcg gaggccgcgg agggaggagc aagtccgcca gatacggcca ctgtcgccag
      121 cgcttgtgct cgcccacagt ctgcgtgcag cctctaccgg gcccaccgca ccgcaacaaa
      181 ccggccactg gagcgggctc ttgggtgtgc gctacggaca tcaaatttgt aggaccaact
      241 tccggtcctc cgcatccggc ttccgctctc tggggtgtgc tgctgctgat cttccggcag
      301 gcggcccgcc agacccccga ccttcttcac ggtcggattc gggctgggtg ttcttcccga
      361 aatgagtttg gtgattaaaa atctgcagcg ggtggtcccc atcagaagag tgccacttcg
      421 caggaagatg gatttagtca ggagtatctt aggagtgaag aaatttgacc tggggatcat
      481 ctgtgttgac aacaagacta ttcagaacat taataggatc tacaggaata aaaatgtccc
      541 aactgacgtg ctttctttct catttcatga gaatctgaaa gctggcgaat ttcctcagcc
      601 acactcaccg gatgattata atctgggaga cattttccta ggggtggagt acattcttca
      661 gcattgcaga gaaagtgagg attactgtga tgtcctgacg gtcacagcca cccatggact
      721 ctgtcacctg ctgggcttca cccacagctc caaagccgag tggcaaaaga tgtacaacca
      781 ggagaagctg gtgctggagg agctgagccg ctacacggga gctaggctcc aacccctgag
      841 caggggcctc tactgatgcc acagagcttt gagacagaga acttgttgga cagagtcccg
      901 tccctctgca agactccagg gagcctctgc ttaccaggga gcccctgagt ggaccacgtg
      961 gagccggaat agatgcaaaa agcaagagga atttttgttc cagtgcactg gggtcttccc
     1021 agacccgaag gagaggcggc gacccccagc acccattcag ggagttttta tatggtttcc
     1081 aggggcagaa gagagcatca gcaactaggc acaacgtgat tggcggagca gtgcaccctt
     1141 taaactgatt ggtctttagg gaatgaagtg acaaggacgt cccttgtctg aaggtgtcct
     1201 gcaggatgtg tccccaccca cagggcagtt ctgccctaag gtctgagaaa tgttaattag
     1261 cctcttcctt ctggaggggc aagtgtttca tgaccttccc aaacttccta agctggcctt
     1321 tttacctcca cagtggatct ctgctggtcc tgttgccctg gagggcctca gcccacacta
     1381 cagcttcact ctgtgagtgg accaagtacc aaggaagtgc ctgtcagccc ttactctgat
     1441 tagaaatcta tgcggactct gttgtaagca gaatcaggcg ttctaagaga agaaacatgg
     1501 acgctcttgt gcttctttgg gtttctagct gtagagtctg ggcagattgc cttgtctccc
     1561 tgaagtggga ggaacgtgcc agaacactga agcctgttct cctaggagga ggcgcctgca
     1621 gaccagcaag cccaaaagga caccttgtgc cctcgccttt cttaagctgt tggctgcaga
     1681 caccacggga cagcccacag accttgtctc ctggggccag agagtcagga gtgtccccca
     1741 tctgtgttgc tgtttgtaat tgttttagat gacctttatt ttatttggag cagggcagtg
     1801 gtggcacacg cctttagtcc cagcacttgg gaggcagagg caggcggatt tctgagttcg
     1861 aggccagcct ggtctacaaa gtgagttcca ggacagccag ggctacacag agaaaccctg
     1921 tctcgaaaaa ccaaaaaaaa aaaggatttt atttggtgtg tgtcatgtgt gggtacacat
     1981 ttcccactgc ggggggtggg gtggtcagct ggggggagat gtctctctcg tttattattt
     2041 tgtccccaga gatggaactc tggttgtcag ccttgccatc ccactgacat cctgcaggcc
     2101 accgtagtcc tgccactggg gctcccctat tggctgttag aggcatggta gttctgctca
     2161 aggcctggaa catggaattc tggtgacctg aagtctagtt caaagcaaca tgcaaatgtc
     2221 tgtgcaaatc tggatcacga gagtcttccc agcaggtagc cagggacctt gaacctagat
     2281 agggtttcct gacccctctg ctgggtgtac ccgcatatac acctatgcca gcctgttccc
     2341 ttcttctcgg ccatctaact ggttcctcgc ctttgagcat ccttaaggaa tgactgcttc
     2401 tgtgcccttc atttttctat ttcccttttt ctctgcttgg tatttctggt ttaatttggt
     2461 ggggtttttg gtttttttgg ttttttgggg ggtttttttg tttttttttt ttgtttttgt
     2521 ttttggtttg gtttgacctt gcagctctgg gcatggaatc caggatcttg tcaggcttgg
     2581 caaggctctg ccacattccc agcctgttgc tcagctgccc taaatctgtg ggttggtcag
     2641 cagctgtctc tgagtccagc cacattgtta tgatgactcc aagcctgagg gggcactatc
     2701 tgccctgttc caggaggcac agcatcctca cttggggctt cctcactttg tgtttattcc
     2761 agatttcatt tcgtccctca cttccctgaa gggcctgtga tgttttttaa tttttaaaaa
     2821 agatttactt gggtatgggg gacttttggt atagcattgg aaatgtaaat gagctaaata
     2881 cctaataaaa aaaagattta cttattttat gtatatgagt acactgtaga tggttgtgag
     2941 ccatcgtgtg attgctggga attgaactta ggatttctgc tcgttccggc cctgctcgct
     3001 ccagcccaaa gatttattaa ttatatgtaa gtacactgta gctgtcttca gataaaccag
     3061 aagagggcgt cagatctcat tacagatggt tgtgagccac tgcgtggttt ctgggatttg
     3121 aactcgacct tcagaagagc agtcagtgct cttaaccgct gagccatctc tccagctggg
     3181 gcctgtgatc ttgatgagag tttcatggac tctgtggatt ggccgctcac acacttgagc
     3241 catctttaaa atctctgggg cgtactgtgc atcttctcag agtaaagttg tgcacagtgg
     3301 tgcagtccct gtcaccactg ttaaggggca tggccaggag aagcttttcc ctgagtcact
     3361 ggggaccccc taagcccact acagggcctg ctcagactct ttagtctccc acaggtggtc
     3421 ctcagacagc aggcttgaaa gggacgggga agactgtgtg tgagggtggg tccatgtaca
     3481 ctcccatagc ttccagaggc tgatggtgct cccagagcca ggatgctccc aggctacttc
     3541 ctccttgtta gcccagcatt gccaggccat ctgagacaaa acatctgcca aatatcttcc
     3601 ttctatcaga tcaataatca tatgagagga aaatcgtgtt agaaacatca tctaggaagg
     3661 aaattatgtg agctctttaa ctggtgcttt taacaaaacc aagtttctct ggaaccacac
     3721 cccaaggcgc actgaaagac aggtctgtct ttatggattc ttctctacct gatgggctgg
     3781 ggtggagatg gaggagagag agcaaccatc caaccctccc ggagtgaaca gtgctttgta
     3841 aacagcgtgt gtaaataccc atacttacac agcctgcagt gcccacgtgc atgcatgtgg
     3901 acctcacatg tacctgggcc ttgttatgat tataaaatgt tataagtatg agtatcttgc
     3961 ctgtgtgtat ttatgtgtgc actcctgatg cccttggagg tcagaagagg acattgacta
     4021 tcctggaact ggagtcacag agagttgtgg attgccatgt ggtgctattg aaagaaaata
     4081 aaacttgagt cctgtgattc atgtaatagc ccaaagagtt gtttgtgagc tttgaagcct
     4141 gggactgaga acatagcaga acaggccagg acatgcctgg gcaggcccat cattaagaca
     4201 ttcctgaggc tgcttggcca taaagataaa gagaatgcaa agacatgtcc agactggcct
     4261 ggcgcctccc tatctcccac ccttctgaca tgggttaaat gttaaccaga tgctctgctg
     4321 ttacctccat ctgcacatac actctgctga tgtttaaatg aaccaatcgt gtgaaaccgc
     4381 gccaattcct cccccagccc cagacccttt tctataaaaa cccctagctt tcaagcctag
     4441 tggtcgacaa ccgcaatctc ctgtgtgaga tacatgtcgg cccggagctc cgtcattaaa
     4501 ctacctcatg tgtttgcatc aaaaaaaaaa aaaaaaaa
//
