LOCUS       NM_001359888            7213 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Mus musculus exportin 7 (Xpo7), transcript variant 1, mRNA.
ACCESSION   NM_001359888 XM_006519361
VERSION     NM_001359888.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7213)
  AUTHORS   Hu,X., Wang,J., Yang,K., Fan,H., Wu,J., Ren,J., Han,G., Li,J.,
            Xue,Z., Liu,X. and Lv,X.
  TITLE     The GWAS SNP rs80207740 modulates erythrocyte traits via
            allele-specific binding of IKZF1 and targeting XPO7 gene
  JOURNAL   FASEB J 38 (10), e23666 (2024)
   PUBMED   38780091
  REMARK    GeneRIF: The GWAS SNP rs80207740 modulates erythrocyte traits via
            allele-specific binding of IKZF1 and targeting XPO7 gene.
REFERENCE   2  (bases 1 to 7213)
  AUTHORS   Lin,Y., Zhan,M. and Xu,B.
  TITLE     Exportin XPO7 acts as an oncogenic factor in prostate cancer via
            upregulation of TCF3
  JOURNAL   J Cancer Res Clin Oncol 149 (10), 7663-7677 (2023)
   PUBMED   37000263
  REMARK    GeneRIF: Exportin XPO7 acts as an oncogenic factor in prostate
            cancer via upregulation of TCF3.
REFERENCE   3  (bases 1 to 7213)
  AUTHORS   Modepalli,S., Martinez-Morilla,S., Venkatesan,S., Fasano,J.,
            Paulsen,K., Gorlich,D., Hattangadi,S. and Kupfer,G.M.
  TITLE     An In Vivo Model for Elucidating the Role of an Erythroid-Specific
            Isoform of Nuclear Export Protein Exportin 7 (Xpo7) in Murine
            Erythropoiesis
  JOURNAL   Exp Hematol 114, 22-32 (2022)
   PUBMED   35973480
  REMARK    GeneRIF: An In Vivo Model for Elucidating the Role of an
            Erythroid-Specific Isoform of Nuclear Export Protein Exportin 7
            (Xpo7) in Murine Erythropoiesis.
REFERENCE   4  (bases 1 to 7213)
  AUTHORS   Markiewicz,L., Uspienski,T., Baran,B., Niedziolka,S.M. and
            Niewiadomski,P.
  TITLE     Xpo7 negatively regulates Hedgehog signaling by exporting Gli2 from
            the nucleus
  JOURNAL   Cell Signal 80, 109907 (2021)
   PUBMED   33383157
  REMARK    GeneRIF: Xpo7 negatively regulates Hedgehog signaling by exporting
            Gli2 from the nucleus.
REFERENCE   5  (bases 1 to 7213)
  AUTHORS   Cantu,I., van de Werken,H.J.G., Gillemans,N., Stadhouders,R.,
            Heshusius,S., Maas,A., Esteghamat,F., Ozgur,Z., van IJcken,W.F.J.,
            Grosveld,F., von Lindern,M., Philipsen,S. and van Dijk,T.B.
  TITLE     The mouse KLF1 Nan variant impairs nuclear condensation and
            erythroid maturation
  JOURNAL   PLoS One 14 (3), e0208659 (2019)
   PUBMED   30921348
  REMARK    GeneRIF: Results found that XPO7 expression was significantly
            downregulated in the presence of the KLF1 Nan variant erythroid
            progenitors, potentially contributing to increased nuclear size.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7213)
  AUTHORS   Kalsotra,A., Xiao,X., Ward,A.J., Castle,J.C., Johnson,J.M.,
            Burge,C.B. and Cooper,T.A.
  TITLE     A postnatal switch of CELF and MBNL proteins reprograms alternative
            splicing in the developing heart
  JOURNAL   Proc Natl Acad Sci U S A 105 (51), 20333-20338 (2008)
   PUBMED   19075228
REFERENCE   7  (bases 1 to 7213)
  AUTHORS   Koury,S., Yarlagadda,S., Moskalik-Liermo,K., Popli,N., Kim,N.,
            Apolito,C., Peterson,A., Zhang,X., Zu,P., Tamburlin,J. and
            Bofinger,D.
  TITLE     Differential gene expression during terminal erythroid
            differentiation
  JOURNAL   Genomics 90 (5), 574-582 (2007)
   PUBMED   17764892
REFERENCE   8  (bases 1 to 7213)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   9  (bases 1 to 7213)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 7213)
  AUTHORS   Koch,P., Bohlmann,I., Schafer,M., Hansen-Hagge,T.E., Kiyoi,H.,
            Wilda,M., Hameister,H., Bartram,C.R. and Janssen,J.W.
  TITLE     Identification of a novel putative Ran-binding protein and its
            close homologue
  JOURNAL   Biochem Biophys Res Commun 278 (1), 241-249 (2000)
   PUBMED   11071879
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK143729.1, AK036837.1, AK039776.1, AA051428.1 and AI431041.1.
            
            On Jan 18, 2018 this sequence version replaced XM_006519361.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143729.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-708               AK143729.1         2-709
            709-2997            AK036837.1         486-2774
            2998-3686           AK143729.1         3001-3689
            3687-4514           AK036837.1         3464-4291
            4515-5801           AK039776.1         901-2187
            5802-5803           AA051428.1         145-146
            5804-7202           AK039776.1         2188-3586
            7203-7213           AI431041.1         1-11                c
FEATURES             Location/Qualifiers
     source          1..7213
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 36.44 cM"
     gene            1..7213
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /note="exportin 7"
                     /db_xref="GeneID:65246"
                     /db_xref="MGI:MGI:1929705"
     exon            1..85
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..3331
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ran-binding protein 16; RAN binding protein 16"
                     /codon_start=1
                     /product="exportin-7 isoform 1"
                     /protein_id="NP_001346817.1"
                     /db_xref="CCDS:CCDS88710.1"
                     /db_xref="GeneID:65246"
                     /db_xref="MGI:MGI:1929705"
                     /translation="MRDSGRKSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDC
                     LSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLA
                     TFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLT
                     NEINQADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLM
                     QLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPS
                     FSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRL
                     LARLKSNYQLGELVKVENYPDVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASV
                     PYVKATEPHMLETYTPEVTKAYITSRLESVHIILRDGLEDPLEDTGLVQQQLDQLSTI
                     GRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGR
                     VSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQ
                     VQKSSKLYRRLSEVLGLNDETMVLSVFIGKVITNLKYWGRCEPITSKTLQLLNDLSIG
                     YSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLG
                     EDEDQYEQFMLPLTAAFEAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSF
                     MMLFEWIYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGIL
                     LFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRL
                     YGDDALENALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVI
                     MYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNRESDCFLHI
                     MQQHPAMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPP
                     EKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS
                     "
     exon            86..232
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            233..326
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            327..493
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            494..559
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            560..664
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            665..830
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            831..904
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1024
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1171
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1344
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1538
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1644
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1780
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1854
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..1935
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..1999
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2108
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2109..2215
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2216..2304
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2305..2412
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2495
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2496..2710
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2711..2849
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            2850..3010
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3109
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            3110..3237
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     exon            3238..7206
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4772..4777
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /note="hexamer: AATAAA"
     polyA_site      4796
                     /gene="Xpo7"
                     /gene_synonym="4930506C02Rik; exp7; Ranbp16"
                     /note="major polyA site"
ORIGIN      
        1 ctttaaatgt ggaactgaag caagaattta aacacatcag aagagtgtgt gctgcacttg
       61 agacatgcgg gactcaggga gaaagagcct ggcccaacta gagaatctgt gcaaacagtt
      121 gtatgaaaca acagatacaa ccactcgact gcaggcagag aaagccttgg ttgaattcac
      181 caacagccct gattgcctga gcaagtgcca gctgctcctc gagagaggaa gttcgtccta
      241 ctcccagctg ctggcagcta catgccttac caagctcgtg tctcggacaa acaacccctt
      301 gccactggag cagcggatag atatccggaa ctatgtgctc aactaccttg ccactcggcc
      361 aaagttggca actttcgtga ctcaagccct catccagctg tatgccagga tcacaaagct
      421 gggctggttt gactgccaga aggatgacta tgtcttcaga aacgcaatca cagacgtcac
      481 aaggttcctg caggacagtg ttgaatactg catcattggc gtcacaattt tatctcagct
      541 caccaatgaa attaatcaag cagacacaac tcatccttta accaaacaca gaaaaatagc
      601 ctcttctttc cgagactcat cactgtttga tatcttcaca ctttcctgca atttactaaa
      661 acaggcatca ggaaagaatc tgaacttgaa tgatgaaagt cagcatggct tgctaatgca
      721 actgctcaaa ctcacccaca actgtctgaa ctttgatttt atcggcacat ctactgatga
      781 gtcctcagac gacctgtgta cagtgcagat ccccaccagc tggagatcag cattcttaga
      841 ttcttcgact ctgcagctgt tttttgacct gtatcattcc attcctccct cgttctcacc
      901 tttggtattg tcctgcttag tacagattgc ctcagtccgg agatccctat ttaacaatgc
      961 tgagagggcc aagtttctct ctcatcttgt tgatggtgtt aaacgaatac tggaaaatcc
     1021 acagagttta tcagacccaa acaattacca tgagttctgc agactactgg ctcggttaaa
     1081 gagtaactac caactgggag aactggtaaa agtggaaaac taccctgatg ttatccgatt
     1141 gatagccaac ttcacagtga ccagcctaca gcactgggaa tttgccccaa atagtgtgca
     1201 ctatctcctg agcctatggc agcggctggc agcctctgta ccatatgtca aagccacaga
     1261 gccccatatg ctggaaacat atactcctga ggttaccaaa gcctatatca catcccgctt
     1321 ggaatctgtg cacatcattc tgagggatgg cctggaagat cccctggaag atacaggtct
     1381 ggtccagcaa cagctggacc agctgtccac catcgggcgt tgtgagtatg agaagacatg
     1441 cgcgctcctt gtgcagctat ttgaccagtc ggcccagtcg taccaagaac tgctgcagag
     1501 tgccagtgcc agcccaatgg acattgcagt gcaggaggga cgactgacgt ggttagtcta
     1561 tatcattgga gctgtgattg gtggccgagt ttcttttgcc agcactgatg agcaagatgc
     1621 aatggatggt gagcttgtct gtcgggtgct ccagcttatg aacctgacag attcccgctt
     1681 ggctcaggct ggtaatgaga agcttgaatt ggccatgctg agtttttttg agcagtttcg
     1741 taagatctac attggggatc aggtgcagaa atcctcaaag ctgtaccgcc gactctcaga
     1801 agttctggga ttgaatgacg agacgatggt gctgagtgtc ttcataggaa aagtcatcac
     1861 caacttgaag tactggggtc gttgtgagcc aatcacctcc aagacactgc agctcctcaa
     1921 tgacctctcc atcggataca gtagcgtaag gaagttagtg aagcttagcg ctgtacagtt
     1981 catgctgaac aatcacacga gcgagcactt ttcatttttg ggtattaaca atcagtccaa
     2041 cctgacagac atgcggtgtc ggactacctt ctacacagca cttgggcgtc tcctcatggt
     2101 ggatttagga gaggatgaag atcagtatga acaattcatg cttcctctaa cagcagcgtt
     2161 tgaggctgtg gcccagatgt tcagcactaa cagcttcaat gaacaggagg caaagagaac
     2221 tctggttggc ctagtgagag acctgagagg gatagccttt gccttcaatg ccaagaccag
     2281 tttcatgatg ctcttcgaat ggatataccc ctcctacatg ccaattctcc agcgggcaat
     2341 tgagctctgg taccatgacc cagcctgtac cactcctgtg ctcaagctga tggctgaatt
     2401 agttcataac agatctcagc gactccaatt tgatgtttca tctcccaatg gtatcttact
     2461 tttccgagaa accagcaaga tgataacaat gtatggcaat cgcatcctga cactaggaga
     2521 ggtgccaaag gatcaggtct atgctttgaa gctcaagggt atctccatct gcttctccat
     2581 gctgaaggct gccctcagtg ggagttatgt caactttggg gtcttccgtc tctatggaga
     2641 tgatgccttg gaaaatgccc tacagacctt catcaaacta ctcctctcta ttcctcatag
     2701 tgacctcctg gattacccca agctcagcca gtcttactac tcactactgg aagtcctgac
     2761 ccaggaccat atgaacttta ttgcaagcct ggaacctcat gtcatcatgt acatcctctc
     2821 ttctatttct gaaggactta ctgcacttga caccatggta tgcacgggct gctgttcctg
     2881 cctagaccat attgtgacgt atctcttcaa acagctgtca cggagcacca agaaaaggac
     2941 aacacccctg aaccgggaga gtgactgctt tctgcatatc atgcagcagc atccagctat
     3001 gatccagcag atgctgtcca cggtgctgaa catcattatc tttgaagatt gtaggaatca
     3061 gtggtctatg tctcgacccc tgcttggctt aatactgctt aatgaaaagt atttttctga
     3121 cctaagaaac agcatcgtca atagccaacc accagagaaa cagcaggcca tgcatctgtg
     3181 ttttgaaaat ttgatggaag gcattgaacg gaatcttctg acgaaaaaca gagacaggtt
     3241 cacccagaac ctgtcagcat tccgtcgaga ggtcaacgac tcaatgaaga attccactta
     3301 tggagtgaat agcaatgaca tgatgagctg acaactctcg gactctacct tgcagagcag
     3361 cgtccctttg gtctggtcca gagggtgaac agttgcaagg gagagagcct ggctgatccc
     3421 ggctccttcc tccaggggta tgggggaaat ggcaaaagtc aaccagctat ttccccagaa
     3481 agtacgggga agtacggggt gtgcgtgcac tcactgaggg acagggcact gctggttcct
     3541 gggggactgg ggtgggaagg ggtggtggga ggagacagac gcacaggcat ctgagcctcc
     3601 ggccgctcct ggggtcaccg tgcagggaga gcccggcgcc ctgccgcagc ctgccttgta
     3661 taaacatgta cattttttca taacgttttc aacaaggttt atattgactc aagtttaaaa
     3721 acaaaagtgt gactgaaaac tttttacaga gtctagtgca ccaatgctga cgtgaggggt
     3781 gatgtatggc gagtgaagaa aatgtgcatt gtggtggcct gaagctttat tggacaagga
     3841 tgtgtgaaag tgcagagata tatttagtga cacagtgtag agaggcaaaa aaggaaaaaa
     3901 ctccaaatgt atattttttc ttactgccct ttccctcccc acccccactg atgcgttcct
     3961 gatgctgtat taaccttgtt attaggaact ctgagccatg cgggagcacc accctcccca
     4021 tccatggatg ctgccctggg ccccccagcc tcctgcagtg acagataact ccagctaaag
     4081 tctctggtgt tcttatctcc atcctttctc ccattttact taaccctcat cctcagaaag
     4141 atgcctcttg ctattaaaag tcggatttat gttttaggat tcttggtctc tatagggaga
     4201 cgacagagaa ttgagccatt tgctctcttg ttgagcaatt tgcatgagtc caccagaggc
     4261 ctaatatgtg tggccataac ttttgtcttc cccagccttt gaggcagtgt gtgtggatgt
     4321 gtgtggatat ttatgtgtgt accctgcact catgaatgta tgaactggag gaagttacta
     4381 caggggaggg ctctcaataa caaggtctac ctagcatgaa gtatttaaca ttctcccttg
     4441 aaaaatatac atttttataa aataaaaacc ataataaatg ttttgaatat taaaaaagaa
     4501 aagtgaacct acagaggaac attggatgga gaaaactctt tgccttgtac tttcccacaa
     4561 ctgctgctag ttatatacat ctctagtaca gctcttaccc atgggacatt accaattagg
     4621 ttttattttt attttcctca atcctcacaa acaagcttat taattttcct tctcctctgg
     4681 cgactgtgtg gtgaatcttt tcttgcgtga tcaggttgcg gatagacttg taagggtgtt
     4741 tgctgcatac agtgtaagca ttgtgaccgc caataaactt cgatggtttc tactgacctg
     4801 gtttcagcag tcacgtgtag tgtgttcagg gatgtgtctc actgtcaaca catggagata
     4861 tttagacaaa catgcttttt ttttttttaa gccagtaggt gcagaagtcc ctgtgtcttg
     4921 taaaactaac gcagactgtg tctgcctcag ctcttctgac tggttcagct cacatactta
     4981 tagcataatg ttctccagag ttgtcaaaat gaagacagtc tacctctttc caggtaataa
     5041 agtggcgacc tacatataag cagtagctga agaaaggccc attgggttag tccttacacc
     5101 tgcctctctg atacaggctg ggcttcattt attaggcctt gacaaggtca gtggcaaatg
     5161 ttttcccctg gaatagaatg tataggccaa atgaagcaaa taatgaagac tagtttctgt
     5221 gatttatggc cctgtactgc acagtgcttt gattacgagg gagcccatgg ctaagaccat
     5281 tgaaaagcag gaacaatata gggcagttgt gggtatctta cctgcaaggg cccaagagcc
     5341 aatcctgaat tccttcttag gagtcctaga aaaaccatcc tggcacatgc tcaggagaac
     5401 ctgggatact aattctgaag taaataagac aaagggacta ggaagctgtc tcacaaacac
     5461 tagaaaaacc ttgaagtaac agctggtcaa caaaacccca gtgtccttcc ctctctccta
     5521 cggaagagac actagggatg atagtacctt tggtcagtca cggcacagtg cttaagcttg
     5581 agatcttcca cggccccaag ctgtgtaaga ctccgctgac aaaggtttgc cctgacatag
     5641 tagtgcatgc ctttagcccc agcaattggg aagcaaagat tggcaaattg aagtttgagg
     5701 tcaggtagga ctacaaagaa accatggatg gggagagaga gaagggaagg tttttaggat
     5761 ttgggaaatg aaaacaggat tagttcaata tataccttgg ctacacaaca aagccattct
     5821 ggactacatg ggaccccacc ccaaacacac attactaatt tcataaaatt taacctaata
     5881 cgaaattcag ttatttttct ttttaccttt ttattttgtt atttttttta tagtccagtc
     5941 attatctccc tccctttctg ccctcccaca attcctcatc ccattcctcc ccccacccct
     6001 ctgaaaggat gtccccacac acccctatac tccaccaggc cttcccattc cctggggcct
     6061 caagtattag gtgcatcttc tctcattgag accagaccag gcagtcctct cctgtatatg
     6121 tgtcagggga cttggaccag ctagtgtatg ctgcctggtt agtggctcaa tgtcagatct
     6181 cactggggag gggttccagg tttgttgaga ctactggccc tcccatgggc tcttcagacc
     6241 attggtcagg tgtaagtatc tgcttctgtc tcagtcagct gctggtagag catctcagag
     6301 ggcagctgtg ctatatatag actcctgtta tgcatgtcct tttgggtctg agatgcctca
     6361 ctcttggtga tattttctag ttccatccat ttgcctgcaa aactcatgat gtcttcgtcc
     6421 ttgatagctg aatagcattc cattgtgtaa atgaaccaca ttatctgtat tcattcttcc
     6481 gttgtgggac atctaggttg ttcccagctt ctggctatca caaataaggc caccatggtc
     6541 gagtacatgc ccaagagtag tatagctggg tcttcaggta gatctatttc caattttctg
     6601 aggaacctcc agattgactt ccagagtggt tgtaccattt tgcaatccca ccagcaatgg
     6661 aggagtgctc ctctttctct acattcttgc caacatgtga tgtcacctta gtttttgacc
     6721 ttagctaatc tggtcggtat aaggtggtat ctcagggtca ttttgatttg tatttccctg
     6781 atcagtaagg actctgaaca ttcaagtgct tctcagtcat ttgagattcc tctgttatga
     6841 attctctgtt tagttgtata ccccattttt ttctattggg ttgtttggtt tttttttgga
     6901 ggttagcttc ttgagttctt tatatatttt ggatattagc gctctatcag atgtggggtt
     6961 agggatgaat ttttttccaa tctgtaggtt gccggaaatc ctataccttc ctcttttctc
     7021 agatgtcatg gaaaggtgta tgttgtggtt atctgtgctg ttcctggaca caagtgtttc
     7081 atctacacag tgatatctgg aataagctac actgaaccct aaattccctt actgatgttt
     7141 attaaatttt attgtgtact atgtatttat tagcttaacc caaataaagc taatattttc
     7201 ctactaaaaa aaa
//
