LOCUS       NM_011728                972 bp    mRNA    linear   ROD 18-DEC-2022
DEFINITION  Mus musculus xeroderma pigmentosum, complementation group A (Xpa),
            mRNA.
ACCESSION   NM_011728
VERSION     NM_011728.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Schubert N, Schumann T, Daum E, Flade K, Ge Y, Hagedorn L, Edelmann
            W, Muller L, Schmitz M, Kuut G, Hornung V, Behrendt R and Roers A.
  TITLE     Genome Replication Is Associated With Release of Immunogenic DNA
            Waste
  JOURNAL   Front Immunol 13, 880413 (2022)
   PUBMED   35634291
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  AUTHORS   Kajitani GS, Quayle C, Garcia CCM, Fotoran WL, Dos Santos JFR, van
            der Horst GTJ, Hoeijmakers JHJ and Menck CFM.
  TITLE     Photorepair of Either CPD or 6-4PP DNA Lesions in Basal
            Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in
            Nucleotide Excision Repair Deficient Mice
  JOURNAL   Front Immunol 13, 800606 (2022)
   PUBMED   35422806
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 972)
  AUTHORS   Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA,
            Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan
            GP, Clatworthy MR and Patel KJ.
  TITLE     Aldehyde-driven transcriptional stress triggers an anorexic DNA
            damage response
  JOURNAL   Nature 600 (7887), 158-163 (2021)
   PUBMED   34819667
REFERENCE   4  (bases 1 to 972)
  AUTHORS   Kajitani GS, Brace L, Trevino-Villarreal JH, Trocha K, MacArthur
            MR, Vose S, Vargas D, Bronson R, Mitchell SJ, Menck CFM and
            Mitchell JR.
  TITLE     Neurovascular dysfunction and neuroinflammation in a Cockayne
            syndrome mouse model
  JOURNAL   Aging (Albany NY) 13 (19), 22710-22731 (2021)
   PUBMED   34628368
  REMARK    GeneRIF: Neurovascular dysfunction and neuroinflammation in a
            Cockayne syndrome mouse model.
REFERENCE   5  (bases 1 to 972)
  AUTHORS   Nakane H, Higaki K, Koyama Y, Nanba E and Kaidoh T.
  TITLE     Autophagy induction on impaired spermatogenesis of xeroderma
            pigmentosum group A gene-deficient mice
  JOURNAL   Biomed Res 41 (5), 237-242 (2020)
   PUBMED   33071259
  REMARK    GeneRIF: Autophagy induction on impaired spermatogenesis of
            xeroderma pigmentosum group A gene-deficient mice.
REFERENCE   6  (bases 1 to 972)
  AUTHORS   de Vries A, van Oostrom CT, Hofhuis FM, Dortant PM, Berg RJ, de
            Gruijl FR, Wester PW, van Kreijl CF, Capel PJ, van Steeg H and
            Verbeek SJ.
  TITLE     Increased susceptibility to ultraviolet-B and carcinogens of mice
            lacking the DNA excision repair gene XPA
  JOURNAL   Nature 377 (6545), 169-173 (1995)
   PUBMED   7675086
REFERENCE   7  (bases 1 to 972)
  AUTHORS   Nakane H, Takeuchi S, Yuba S, Saijo M, Nakatsu Y, Murai H,
            Nakatsuru Y, Ishikawa T, Hirota S, Kitamura Y et al.
  TITLE     High incidence of ultraviolet-B-or chemical-carcinogen-induced skin
            tumours in mice lacking the xeroderma pigmentosum group A gene
  JOURNAL   Nature 377 (6545), 165-168 (1995)
   PUBMED   7675085
REFERENCE   8  (bases 1 to 972)
  AUTHORS   Tanaka K, Miura N, Satokata I, Miyamoto I, Yoshida MC, Satoh Y,
            Kondo S, Yasui A, Okayama H and Okada Y.
  TITLE     Analysis of a human DNA excision repair gene involved in group A
            xeroderma pigmentosum and containing a zinc-finger domain
  JOURNAL   Nature 348 (6296), 73-76 (1990)
   PUBMED   2234061
REFERENCE   9  (bases 1 to 972)
  AUTHORS   Tanaka K, Satokata I, Ogita Z, Uchida T and Okada Y.
  TITLE     Molecular cloning of a mouse DNA repair gene that complements the
            defect of group-A xeroderma pigmentosum
  JOURNAL   Proc Natl Acad Sci U S A 86 (14), 5512-5516 (1989)
   PUBMED   2748601
REFERENCE   10 (bases 1 to 972)
  AUTHORS   Lin,P.F. and Ruddle,F.H.
  TITLE     Murine DNA repair gene located on chromosome 4
  JOURNAL   Nature 289 (5794), 191-194 (1981)
   PUBMED   7453821
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI172779.1, CB058423.1, BP771655.1 and AI838722.1.
            
            [WARNING] On Oct 13, 2023 this sequence was replaced by
            NM_011728.3.
            
            On Jun 16, 2009 this sequence version replaced NM_011728.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X74351.1, CA984292.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AI172779.1         22-31
            11-609              CB058423.1         13-611
            610-951             BP771655.1         52-393              c
            952-972             AI838722.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 24.49 cM"
     gene            1..972
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /note="xeroderma pigmentosum, complementation group A"
                     /db_xref="GeneID:22590"
                     /db_xref="MGI:MGI:99135"
     exon            1..263
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..910
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /note="xeroderma pigmentosum group A-complementing protein
                     homolog"
                     /codon_start=1
                     /product="DNA repair protein complementing XP-A cells
                     homolog"
                     /protein_id="NP_035858.2"
                     /db_xref="CCDS:CCDS18146.1"
                     /db_xref="GeneID:22590"
                     /db_xref="MGI:MGI:99135"
                     /translation="MATAEEKQTSPEPVAADEPAQLPAAVRASVERKRQRALMLRQAR
                     LAARPYPAAAATGGVASVKAAPKMIDTKGGFILEEEEEKHEIGNIVHEPGPVMEFDYT
                     ICEECGKEFMDSYLMNHFDLPTCDSCRDADDKHKLITKTEAKQEYLLKDCDLEKREPA
                     LRFLVKKNPRHSQWGDMKLYLKLQVVKRALEVWGSQEALEDAKEVRQENREKMKQKKF
                     DKKVKELRRAIRSSVWKRETTTHQHKYGPEENLEDDMYRKTCTLCGHELTYEKM"
     exon            264..371
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
     exon            372..477
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
     exon            478..643
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
     exon            644..761
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
     exon            762..955
                     /gene="Xpa"
                     /gene_synonym="Xpac"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctccttgcc tggtgatgga gtagggccgg gtacttgtgg ctccgctgtt caccaacaat
       61 acgcgttccc ttcctacgga gtgtgtaggc gatggcgacg gccgaggaaa agcagacgtc
      121 acctgagccc gtggccgcgg acgagcccgc gcagctgccg gccgccgtac gcgcgagcgt
      181 ggagcggaag cgacagcggg cactgatgct gcgccaggct cggctggctg cgcggcccta
      241 ccccgcggcg gcggccaccg gaggcgtggc cagtgtaaaa gcagctccca aaatgattga
      301 caccaaaggt ggcttcattt tagaagagga agaagagaaa cacgagattg gaaacattgt
      361 tcatgaacca gggcccgtca tggagtttga ttacaccatc tgtgaagaat gcgggaaaga
      421 gttcatggac tcgtacctta tgaaccactt tgatctgcca acgtgtgaca gctgcagaga
      481 tgctgatgat aaacacaagc ttataaccaa gacagaagcg aagcaagagt accttctgaa
      541 ggactgtgat ctagagaaga gagagccagc gctcaggttc cttgtgaaga agaacccacg
      601 ccattcacag tggggcgata tgaagctcta cctaaagcta caggtggtaa agcgggctct
      661 tgaagtgtgg ggtagccagg aagctctgga agatgcaaag gaagtgaggc aggaaaaccg
      721 agaaaaaatg aagcagaaga agtttgataa aaaagtaaaa gaattgcggc gagcaataag
      781 aagcagtgta tggaaaagag agacaaccac tcaccaacat aaatatggac cagaggaaaa
      841 cttagaagat gacatgtacc gcaagacttg taccttgtgt ggccacgaac tgacatatga
      901 aaaaatgtga ctttttaaaa aatttatatt caaataaaga ccctgttcaa agttcaaaaa
      961 aaaaaaaaaa aa
//
