LOCUS       NM_011644               4506 bp    mRNA    linear   ROD 18-APR-2023
DEFINITION  Mus musculus Xndc1-transient receptor potential cation channel,
            subfamily C, member 2 readthrough (Xntrpc), transcript variant
            Xndr-Trpc2 protein, mRNA.
ACCESSION   NM_011644
VERSION     NM_011644.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4506)
  AUTHORS   Frankenberg S, Schneider NY, Fletcher TP, Shaw G and Renfree MB.
  TITLE     Identification of two distinct genes at the vertebrate TRPC2 locus
            and their characterisation in a marsupial and a monotreme
  JOURNAL   BMC Mol Biol 12, 39 (2011)
   PUBMED   21854574
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC150275.2 and AC132297.4.
            
            On Nov 13, 2013 this sequence version replaced NM_011644.2.
            
            Summary: This locus represents naturally occurring readthrough
            transcription between the neighboring Xndr (XRCC1 N-terminal
            domain-related) and Trpc2 (transient receptor potential cation
            channel, subfamily C, member 2) genes on chromosome 7. Readthrough
            transcripts include one that encodes a fusion protein that shares
            sequence identity with each individual gene product and one that is
            a candidate for nonsense-mediated mRNA decay (NMD), and thus is
            unlikely to produce a protein product. [provided by RefSeq, Nov
            2013].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes an Xndr-Trpc2 protein.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 22064,
                                      102443350
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AC150275.2         208907-209049
            144-285             AC150275.2         210863-211004
            286-441             AC150275.2         213485-213640
            442-620             AC150275.2         215437-215615
            621-706             AC150275.2         216421-216506
            707-879             AC150275.2         216693-216865
            880-955             AC150275.2         218217-218292
            956-1083            AC150275.2         219171-219298
            1084-1189           AC150275.2         219729-219834
            1190-1235           AC150275.2         220661-220706
            1236-1955           AC150275.2         221549-222268
            1956-2168           AC150275.2         224086-224298
            2169-2333           AC132297.4         128626-128790
            2334-2508           AC132297.4         129226-129400
            2509-2709           AC132297.4         130211-130411
            2710-2872           AC132297.4         131023-131185
            2873-2965           AC132297.4         131633-131725
            2966-3158           AC132297.4         134640-134832
            3159-3286           AC132297.4         135338-135465
            3287-3365           AC132297.4         135605-135683
            3366-3498           AC132297.4         136278-136410
            3499-4506           AC132297.4         136967-137974
FEATURES             Location/Qualifiers
     source          1..4506
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7"
     gene            1..4506
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /note="Xndc1-transient receptor potential cation channel,
                     subfamily C, member 2 readthrough"
                     /db_xref="GeneID:102443351"
                     /db_xref="MGI:MGI:5546370"
     exon            1..143
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..3893
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /codon_start=1
                     /product="Xndr-Trpc2 readthrough"
                     /protein_id="NP_035774.2"
                     /db_xref="GeneID:102443351"
                     /db_xref="MGI:MGI:5546370"
                     /translation="MAPVKISHVVSFSSQDPKYPVENLLNPDSHRGPWLSCPQDKTGQ
                     LKVEFQLERAVPISYIDVGNCGCAFLQIDVGRSSWPLDRPFVTLLPATMLMSRTDSKS
                     GKNRSGVRMFKDGDFLTPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLGSLADP
                     VVDPSAPGSSGLNQNSTDVLESDPRPWLTNPSIRRTFFPDPQTSTKEISELKGMLKQL
                     QPGPLGRAARMVLSAARKAPPASVVSPNNSHGEPGPSRAESAEPRAEEPNRKTAVGRR
                     KRRKVQEPRRSLSNSSSQPNRRTGRTRQRQHRPQTKSDDGGVQAAGQCPICAGFFSIE
                     TLPQHAATCGESPPPQPASPASLSSSESVLRRHHVALTPVPLVPKPQPNWTEIVNKKL
                     KFPPTLLRAIQEGQLGLVQQLLESSSDASGAGPGGPLRNVEESEDRSWREALNLAIRL
                     GHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSL
                     AFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNAR
                     RYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIA
                     LESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRL
                     AVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWL
                     APKSQLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLH
                     MIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCR
                     DASDSTTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQI
                     SIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQESEKLGNFNETFQFLFWTMFGME
                     EHTVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFA
                     RSKLYLSYFREGLTLPVPFNILPSPKAAFYLVRRIFRFLCCGSSCCKAKKSDYPPIGT
                     FTNPGARAGSAGEGERVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTV
                     SRLQSEVASVQKNLAAGGAPRPPDGASILSRYITRVRNSFQNLGPPTSDTPAELTMPG
                     IVETEVSLGDGLDGTGEAGAPAPGEPGSSSSAHVLVHREQEAEGSGDLLLEGDLETKG
                     ES"
     exon            144..285
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            286..441
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            442..620
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            621..706
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            707..879
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            880..955
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1083
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1189
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1235
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1955
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2168
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2333
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2334..2508
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2709
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2710..2872
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2873..2965
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2966..3158
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..3286
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3287..3365
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3498
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3499..4506
                     /gene="Xntrpc"
                     /gene_synonym="Xndr-trpc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctaccaagag caaaacatca acagtaccac cgtggctaca gaagacatcg ggggaggaag
       61 cgtgtcttcc tcgcacttaa ggaagctggt ggcgtccgat ggctcctgtg aagatcagcc
      121 atgtggtgtc attttcctct caggatccca aatatcctgt ggagaacttg ctgaacccag
      181 acagtcacag gggaccctgg ctcagctgcc ctcaggacaa gactggacaa ctgaaagtgg
      241 agtttcagct ggagagggca gtgcccataa gctatattga tgttggaaac tgtggctgtg
      301 ctttcctaca gattgatgtg ggtcgttctt cctggcccct ggacagacct ttcgtcaccc
      361 tgctccctgc caccatgcta atgtcccgca ctgactccaa gtcggggaag aaccgctcag
      421 gggtccggat gtttaaagat ggtgatttcc tgactccagc ctcaggagag tcctgggatc
      481 gacttcgatt gacctgctcc caacctttca cacgtcatca gtcctttggc ctggccttcc
      541 tacgagtgcg ttcctctctg ggctctctgg ctgaccctgt agtagatccc tcagcccctg
      601 ggagctctgg gcttaaccag aactctacag atgtgctgga gtctgatcct aggccctggc
      661 tgactaatcc ttctatccgg aggacattct tccccgatcc ccagacgagc accaaggaaa
      721 tttcagagct caagggtatg ttgaagcagt tgcagccagg gcctctgggg cgggcagccc
      781 gcatggtgct ttctgctgcc cgtaaggccc ctccagccag tgtggtaagc ccaaacaaca
      841 gccacggaga accaggtccc agccgtgcag agagtgcaga gcccagagca gaagaaccaa
      901 acaggaagac ggctgtgggc agaaggaaga ggaggaaagt gcaggagcca aggagatcgt
      961 tgtccaactc gagttctcag ccaaatagga ggacaggaag gacaagacaa agacagcacc
     1021 gacctcagac caaaagtgat gacggtggtg tgcaggctgc tggacagtgt cctatttgtg
     1081 caggtttctt cagtattgag actcttcccc agcatgctgc aacttgtgga gagagccccc
     1141 caccccagcc agcttctcct gcctccttgt cttcctcgga gtccgtgctg agacgtcatc
     1201 atgtggcact aacacccgtt ccccttgtcc ccaagccaca gcccaactgg actgagattg
     1261 tgaacaaaaa gctcaaattc ccccccacac tcctgcgtgc catccaggag ggccagctgg
     1321 gtcttgtgca gcagctgctg gaatccagtt ccgatgcctc gggtgctggg ccaggtggtc
     1381 ctctgcggaa tgtggaagag tctgaggacc gctcctggag ggaagccctc aacctggcca
     1441 tccgcctggg ccacgaggtc atcactgatg ttctgctggc caatgtcaaa ttcgactttc
     1501 ggcagatcca cgaagccctg ctagtggctg tggacacaaa ccagccagca gtggtgcgtc
     1561 gcctgctagc gcggctggag cgggagaaag gtcgaaaagt agacaccaag tctttctctc
     1621 tagccttctt tgactcatcg attgatggct cccgctttgc ccctggtgtc actccactca
     1681 cactggcctg ccagaaggac ctgtatgaga ttgcccagct gcttatggac cagggccata
     1741 ccattgctcg gccccaccca gtttcctgtg cctgcctcga gtgcagcaat gcccgccgat
     1801 acgacctgct gaagttctca ctatcccgaa tcaacaccta ccgaggcatt gcaagccggg
     1861 ctcacctctc gctggccagt gaggatgcca tgctggccgc ttttcagctc agccgggagc
     1921 tcaggcgcct tgcacgaaag gagcctgagt ttaagcctca gtacattgcc ctggagtctc
     1981 tctgccagga ctatggcttc gagttgctgg gcatgtgccg aaatcagagt gaggtcaccg
     2041 cagtgctcaa tgacctgggt gaggatagtg agactgagcc tgaggctgag ggcctgggtc
     2101 aggcctttga ggagggcatc cccaacctgg caagactgcg gttggctgtc aactacaacc
     2161 agaaacagtt tgtagcacat cccatctgcc agcaagttct gtcttccatc tggtgtggga
     2221 acctggctgg ctggcgtgga agcaccacca tctggaagct ctttgttgcc ttcctcatct
     2281 tcctcaccat gcccttcctc tgcattggct actggctggc gcccaagtcc cagctgggcc
     2341 gcctgctgaa gatcccggtg ctgaagttcc tgctgcattc tgcctcctac ctgtggttcc
     2401 ttatcttctt gctgggagag tctctggtca tggagaccca gctgagcacc ttcaaaggcc
     2461 gcagccagag tgtctgggag acttcactac atatgatctg ggtcacaggc ttcctatggt
     2521 ttgaatgcaa ggaggtgtgg atcgagggct tgcggagcta cctcctggac tggtggaact
     2581 tcctggacgt ggtcatcctg tccctgtact tggcatcctt tgcactgcgc ctcctcctgg
     2641 ctgggcttgc ctacatgcac tgccgtgatg cctcagacag caccacctgc cgctatttca
     2701 ccacagctga gagaagtgag tggcgtacag aggaccccca gtttctggct gaggtgctct
     2761 ttgctgtcac cagcatgctc agcttcaccc gactggcata tattctgcca gctcacgaat
     2821 cgctgggcac actgcagatc tccatcggca agatgattga cgacatgatc cggttcatgt
     2881 tcatcctcat gatcatcctg actgccttcc tctgtggcct caacaacatc tatgtgccct
     2941 accaggaatc cgagaagcta ggcaatttca acgaaacgtt ccagtttctc ttttggacca
     3001 tgttcggcat ggaagagcac acagtggtgg acatgcctca gttcctggtg cctgagttcg
     3061 tgggcagggc catgtacggc atctttacca tcgtcatggt cattgtgcta cttaacatgc
     3121 ttattgccat gatcaccaac tccttccaga agatcgagga tgatgctgat gtggagtgga
     3181 agtttgctcg ctccaagctc tacctgtcct acttccgaga gggtctgacg ctgcctgtgc
     3241 cctttaacat cctgccatcc ccaaaggccg ccttctacct cgtcaggaga attttccggt
     3301 tcctttgctg tggctcctcc tgctgcaaag ccaagaagtc ggactacccg cccatcggga
     3361 cctttaccaa ccccggggca agggcgggct ccgccgggga aggagaacgc gtgtcctacc
     3421 gccttcgagt catcaaggct ctggtgcagc gctacataga gactgcccgg cgcgagttcg
     3481 aggagacccg tcggaaagac ctgggcaaca gactgacaga gctgaccaag actgtgtctc
     3541 gactgcaaag cgaggtggcc agtgtgcaga agaacctggc ggcgggaggg gcaccacggc
     3601 ctccggatgg tgccagcatc ctcagtagat acatcacccg agtgcgcaac agcttccaga
     3661 acctgggccc ccctacctct gacaccccag cagagctgac tatgcctggg attgtggaga
     3721 ccgaagtctc tttaggagat ggccttgatg gcacaggtga agctggagct cccgctcctg
     3781 gagagcccgg ctcttcctcc tctgcccatg tgctggttca cagggagcaa gaagcagagg
     3841 ggtcagggga cttgctcctg gaaggagatc tggagaccaa gggcgagtcc taaggcaaca
     3901 gaagggtctc ttctgtcact aagtgcagct gctgtgttgg gtagagccag ggtctcacag
     3961 tagaagacca tggtgctttt taatattatt attatttatt ttattttatt ttattttatt
     4021 tgtttttttg cctcagtaaa atttctgctg tggaagtcag atggtagtct ccatctcttg
     4081 gcatcctaag attccttcct ttacttcccc taaaatggac gctgtgggag gagggaagag
     4141 agaaacagct tgctttgagt tctggggttt agaatcctac ttttgggatt ccttaggtct
     4201 ttagtgaaaa acgttctggc ctaggagact ggaagactgg gagctaggag gccagagaag
     4261 caggagacct gagtgggtag gtctgagaga tgggaggcct ggaggtggtg ccctttcttg
     4321 gcctggcatt ctcttcaggg atgggtatca atctatcccc tccctgactt catgaggccc
     4381 ctgtggctgt taagaagcat caggcacaga ggctacaatg tgtgacccgg atgactggga
     4441 aattagtttc catccctcga ctttcaagct tgtcaaggac aaatgacgtc atgcaataaa
     4501 ccagtc
//
