LOCUS       NP_001011873             373 aa            linear   ROD 02-MAY-2024
DEFINITION  XK-related protein 9 [Mus musculus].
ACCESSION   NP_001011873 XP_358536
VERSION     NP_001011873.1
DBSOURCE    REFSEQ: accession NM_001011873.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 373)
  AUTHORS   Suzuki,J., Imanishi,E. and Nagata,S.
  TITLE     Exposure of phosphatidylserine by Xk-related protein family members
            during apoptosis
  JOURNAL   J Biol Chem 289 (44), 30257-30267 (2014)
   PUBMED   25231987
  REMARK    GeneRIF: Unlike Xkr8, which is ubiquitously expressed, Xkr4 and
            Xkr9 expression is tissue-specific.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC116708.19.
            
            On Feb 13, 2005 this sequence version replaced XP_358536.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY534255.1, SRR5189685.307077.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 4.31 cM"
     Protein         1..373
                     /product="XK-related protein 9"
                     /note="X Kell blood group precursor related family member
                     9 homolog"
                     /calculated_mol_wt=43140
     Site            8..28
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Region          10..345
                     /region_name="XK-related"
                     /note="XK-related protein; pfam09815"
                     /db_xref="CDD:462912"
     Site            38..58
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            166..186
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            206..226
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            230..250
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            256..276
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            295..315
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            318..338
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5GH62.1)"
     Site            357..358
                     /site_type="cleavage"
                     /note="Cleavage, by caspase-3, caspase-6 and caspase-7.
                     /evidence=ECO:0000305|PubMed:25231987; propagated from
                     UniProtKB/Swiss-Prot (Q5GH62.1)"
     CDS             1..373
                     /gene="Xkr9"
                     /gene_synonym="Gm1620; XRG9"
                     /coded_by="NM_001011873.2:465..1586"
                     /db_xref="CCDS:CCDS14824.1"
                     /db_xref="GeneID:381246"
                     /db_xref="MGI:MGI:2686466"
ORIGIN      
        1 mkytkcnfmm svlgiiiyvt dlvadivlsv ryfhdgqyvl gvltlsfvlc gtlivhcfsy
       61 swlkadleka gqeneryfll lhclqggvft rywfalrtgy hvvfkhsdrk snfmeeqtdp
      121 hkeaidmatd lsmlrlfety legcpqlilq lyaflecgqa nlsqcmvimv sccaiswstv
      181 dyqialrksl pdknllrglw pklmylfykl ltllswmlsv vlllfvdvrv alllllflwi
      241 tgfiwafinh tqfcnsvsme flyrivvgfi lvftffnikg qntkcpmscy ytvrvlgtlg
      301 iltvfwiypl sifnsdyfip isativlall lgiiflgvyy gnfhpnrnve pqldetdgka
      361 pqrdcriryf lmd
//
