LOCUS       NM_001113350            2855 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus X-linked Kx blood group related 5 (Xkr5), transcript
            variant 1, mRNA.
ACCESSION   NM_001113350
VERSION     NM_001113350.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2855)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2855)
  AUTHORS   Suzuki,J., Imanishi,E. and Nagata,S.
  TITLE     Exposure of phosphatidylserine by Xk-related protein family members
            during apoptosis
  JOURNAL   J Biol Chem 289 (44), 30257-30267 (2014)
   PUBMED   25231987
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY534251.1.
            
            On Nov 6, 2013 this sequence version replaced NM_001113350.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY534251.1, SRR11927938.3619985.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2855              AY534251.1         1-2855
FEATURES             Location/Qualifiers
     source          1..2855
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 10.33 cM"
     gene            1..2855
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /note="X-linked Kx blood group related 5"
                     /db_xref="GeneID:319581"
                     /db_xref="MGI:MGI:2442327"
     exon            1..100
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..2073
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /note="isoform a is encoded by transcript variant 1;
                     XK-related protein 5; X Kell blood group precursor-related
                     family, member 5"
                     /codon_start=1
                     /product="XK-related protein 5 isoform a"
                     /protein_id="NP_001106821.1"
                     /db_xref="CCDS:CCDS52495.1"
                     /db_xref="GeneID:319581"
                     /db_xref="MGI:MGI:2442327"
                     /translation="MHAGLLGLSALLQAAEQSARLCSIVFYFATGRLLWGWLALSVLL
                     PGFLVQALSFLWFRADGHQGQWWLAVLHLLQLGVWKRHWDSVATALWKGKEAPSWGQL
                     HLQEADLSALRLLEALLQTGPHLLLQAYVFLASDFTDIVPGISALLSWSSLSWALVSY
                     NRFLGIMKPGHHTMLWAALLCQQLWRMGMLGARVLSLVLFCRVYRVWVLVVGGAHWLV
                     MTFWLVAQQSDIVESTCHWRLFNLLVGAVFILCYINFWDSPSRSRVASFYLVMLLENS
                     ILLLLATDFLQGVPGTSLWTVVGVLSGFLIGCASLVIYYSLLHPKSSDIQQSFMRKCC
                     GPIEDNKPESEPPPRAVDPTGEMPDSSSWCQEESYELTSLDKAPSPEQNTAEVGLGEQ
                     RSGESSFFSHHHWLLLKLALKTGSVSRINAALGGDSPGCSCPPLLGSSQHCDLQRKPL
                     FSHQDLPSSPCDPLTLEKGSEYVGAPKAEMESLETSSYLSFASELEDNATTQKPPATQ
                     EDSPKLAGSKADLAAQGKETEGPLQGKEGQESTTLYFSAAMDRTTSHQRGSPVVLRIS
                     HSETLVESRPGQPALPQAVTKPFPVTVANISPIPGRNFRPSAELPGRAPDSSECEEWK
                     DAARDPSMQSSLPKMRLKAAEEPCFTSTPKSESIQRDYSCRDRVRQEMSFFI"
     exon            101..284
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     exon            285..469
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     exon            470..679
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     exon            680..849
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     exon            850..961
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     exon            962..2838
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2818..2823
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /note="hexamer: AATAAA"
     polyA_site      2838
                     /gene="Xkr5"
                     /gene_synonym="5430438H03Rik; XRG5"
                     /note="major polyA site"
ORIGIN      
        1 gggcagggga aggggcgggc acaggcagca gcagctcaga agatgcacgc ggggctcctg
       61 gggctctctg ccctgctgca ggcggccgag caaagcgcgc gcctctgctc catagttttc
      121 tactttgcca cgggtcgtct cctctggggg tggctggccc tttctgtcct cctgcccggc
      181 ttcttggtcc aggccctgag ctttctgtgg ttccgagcag atgggcatca gggtcagtgg
      241 tggctggcgg tactgcatct tctgcaactt ggcgtctgga agcggcactg ggactctgtg
      301 gcaacggctc tgtggaaggg aaaggaggct cccagctggg gacagctgca cctgcaggag
      361 gctgacctgt cagccctacg gctcctggag gctctgctgc agacagggcc ccacctgctg
      421 cttcaggctt acgtgttcct agcctctgac ttcacagaca ttgtgccagg aatcagtgcc
      481 ctactctcct ggtcttcact gtcctgggct ctagtgtcat acaaccgttt cctgggcatc
      541 atgaagccag gccaccatac catgctatgg gctgctctct tgtgccagca gctctggagg
      601 atgggcatgc tgggtgctcg tgtgctaagc ctggttctgt tctgccgagt ttaccgtgtg
      661 tgggttttgg tggttggagg tgctcactgg ctagtgatga ccttctggct cgtggcccag
      721 cagagcgaca ttgtagagag cacctgccac tggaggctgt tcaatctgct ggtgggggcc
      781 gtgttcatcc tctgctacat caatttctgg gacagccctt ccagaagcag ggtggccagc
      841 ttctacttgg ttatgctgct ggagaactcc atactcttac tactggccac tgactttctg
      901 cagggagtac cagggaccag cctgtggact gtggtgggag tcttgtctgg atttctgatt
      961 gggtgtgcat cgctggttat ttattacagc ttactacacc ctaagtcctc agacatccag
     1021 cagagcttca tgaggaaatg ctgtggcccc atcgaggata acaaacctga atcagaacct
     1081 cctcccaggg ccgtggatcc cacaggggag atgccagaca gctcaagctg gtgccaagag
     1141 gaaagctatg agctaacaag tctagataag gcccccagcc cagagcagaa cactgcagag
     1201 gtggggctcg gggagcagag atctggggag tcctctttct tcagccacca ccactggctg
     1261 ttgctgaaac tcgctctcaa gacaggaagt gtatctagga tcaacgcagc cctcggaggt
     1321 gacagccctg gctgctcctg tccccctctg ctggggtcga gtcaacactg tgatctgcag
     1381 aggaaacccc tgttttccca tcaagacctc ccatcctctc cctgtgaccc tttgaccttg
     1441 gagaaagggt ctgagtacgt aggggctccg aaagcagaga tggagtcatt ggaaacttca
     1501 agctatctct cctttgccag cgagcttgag gacaatgcaa caacccagaa gccaccagct
     1561 acccaggagg acagtccaaa gctggctggg tccaaggctg accttgcagc tcaggggaag
     1621 gagacagaag gtcccctgca ggggaaggaa ggacaggaga gcacaacact gtatttcagt
     1681 gccgccatgg acagaaccac atcccaccaa agaggcagcc cagtagttct gcggatatcc
     1741 cactcggaga ctctggtaga gagcagacct gggcagcctg cgctgcctca ggcagtcact
     1801 aagccctttc ctgttaccgt ggccaatatt agtcccattc caggtagaaa cttccgcccc
     1861 agtgcagagc ttcctggaag agccccagat agttcagagt gtgaggagtg gaaggacgcg
     1921 gcaagggacc cgagtatgca gagctcattg ccgaagatga ggctgaaggc agctgaagag
     1981 ccctgcttca catctacccc taagtcggag tccatccaaa gggactacag ctgcagggac
     2041 agggtgagac aggagatgag ctttttcatc tgaccctagc cgtggtggga taagacaaca
     2101 ggtcaataca tcagactggc cgctcagcat catgggaaga gaaatcccac acgcaacgcc
     2161 tgagttcttc taattctggc ctccatctgc atacctgaaa agacgaaggg acgggattgg
     2221 atgatgtcta accccacacc ccaccccacc cccacccccg tacgcatcag acttggcact
     2281 gacgcacagc aaaactcacg gacagtggga agaagcgaag gggcctccag gtcccttttc
     2341 gagctgcttg aaccctacct agtatgtctc ttctcggctt ccaaaaaatg caaaggaaag
     2401 aatccacttg catcctgggt cctttaacct tttaaccgat cctcacattg gatggctatt
     2461 aatcactttt taaaaaattg tctccaaggt cccttgaggc aacgtatata gctgtttgca
     2521 accattgcac accaaagccc cacggggaaa ggaacttggc cagcttaatc agctgcacta
     2581 ttaatcacct ttttaaaaaa tacttttggg actgaagaga tggcccagca gttaagatcc
     2641 tgctcctccg gaggacccag gttcaattaa ttcccagtat ttatttggta actcatgacc
     2701 acctgtaact tcagtgcccg ggagacaaca gtcatcttct ggcctctgtg cacacggcac
     2761 acccatgatt catgtcatct aggcaggcaa aataccccta cacctaataa ttttaaaaat
     2821 aaaaccgtgt ttcccagaaa aaaaaaaaaa aaaaa
//
