LOCUS       NM_001357965            2850 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WSC domain containing 1 (Wscd1), transcript variant 3,
            mRNA.
ACCESSION   NM_001357965
VERSION     NM_001357965.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2850)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2850)
  AUTHORS   Ertunc,N., Phitak,T., Wu,D., Fujita,H., Hane,M., Sato,C. and
            Kitajima,K.
  TITLE     Sulfation of sialic acid is ubiquitous and essential for vertebrate
            development
  JOURNAL   Sci Rep 12 (1), 12496 (2022)
   PUBMED   35864127
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2850)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2850)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 2850)
  AUTHORS   Feng,W., Leach,S.M., Tipney,H., Phang,T., Geraci,M., Spritz,R.A.,
            Hunter,L.E. and Williams,T.
  TITLE     Spatial and temporal analysis of gene expression during growth and
            fusion of the mouse facial prominences
  JOURNAL   PLoS One 4 (12), e8066 (2009)
   PUBMED   20016822
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2850)
  AUTHORS   Muhlfriedel,S., Kirsch,F., Gruss,P., Chowdhury,K. and Stoykova,A.
  TITLE     Novel genes differentially expressed in cortical regions during
            late neurogenesis
  JOURNAL   Eur J Neurosci 26 (1), 33-50 (2007)
   PUBMED   17614941
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB647482.1, CX219865.1, BC063070.1 and BQ043204.1.
            
            Transcript Variant: This variant (3) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                BB647482.1         1-30
            31-712              CX219865.1         1-682
            713-2831            BC063070.1         621-2739
            2832-2850           BQ043204.1         574-592
FEATURES             Location/Qualifiers
     source          1..2850
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 43.62 cM"
     gene            1..2850
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /note="WSC domain containing 1"
                     /db_xref="GeneID:216881"
                     /db_xref="MGI:MGI:2448493"
     exon            1..215
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            216..904
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     CDS             487..2205
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /note="WSC domain-containing protein 1"
                     /codon_start=1
                     /product="sialate:O-sulfotransferase 1"
                     /protein_id="NP_001344894.1"
                     /db_xref="CCDS:CCDS24975.1"
                     /db_xref="GeneID:216881"
                     /db_xref="MGI:MGI:2448493"
                     /translation="MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQ
                     ALRAPGSLQALPVATVALGVGLLDGRSLRDPHSSPDLLLDVDTLRSPLARLPPGIRWP
                     RRNRSSLRRRWLHHLTSDPQGPPTLSPEASGPANHNRGNYLGCFSEEGQERTLKGAVF
                     YDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSM
                     CGAVRRLSVYSVGLQQPGSKKRRTATYRGCFPLPENVTHTFSSSMTQANMTVETCSGF
                     CSQKEFPLAILRGWDCYCAYPTPQFSLRDAVDGALCSQAPETQGLPGYCEVYQTPVQD
                     TRCTDRKFLPDKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKG
                     EKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDR
                     NWKSKEWPEFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRHSLVPTLREMVAFLNVS
                     VSEERLLCVENNKEGSFRRRGRRPHDQEPFTPEMKDLINGYIRTVDQALRDHNWAGLP
                     REYVPR"
     exon            905..1019
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1204
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1326
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1486
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1651
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1852
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..2833
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2795..2800
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /note="hexamer: CATAAA"
     polyA_site      2831
                     /gene="Wscd1"
                     /gene_synonym="mKIAA0523"
                     /note="major polyA site"
ORIGIN      
        1 tgcgcccgcc actcgctgta ctccgcgccc gcggctcagc tgggcgcccg cccgctccgc
       61 cactgctcag cgcggaagtc cgcagcctcg gggagctgcg cgacgcgggc ctgggagcgc
      121 gggtgcgctt gctacaggcg tctgagcttt gggcactgcg ggctgcgggc ttggcgcccc
      181 ggaaggcggg tgccccaatc ggctgtgatc gctgggttcc tgagactgac gagagccagg
      241 agagctaagg aatggggaaa atggtgaccc ctgggcagaa gctaccaaca aggggcttgt
      301 ggctgccgga gagaagtgat gatgacattt gaaacccaca gggacagaag cccacaagtg
      361 tgctgacacc accggtgtca agagtcagga tgctgggatg atgcccttgg aggccctggc
      421 gtccctcctg cccaggtgct aggagccgtc cccaggctcc agcttggagc cctgctgccc
      481 aggggcatgg ccaaaccttt cttcagactc cagaagtttc tccgcagaac acagttcctg
      541 ctactcttcc tcacggccgc ctacctgatg accggcagcc tgctgctcct gcagcgggcc
      601 agagtggccc tcccacaggc cctccgggct cccggcagcc tgcaggcctt accagtggcc
      661 accgttgcac tgggtgtggg tctactggac ggcaggagcc ttcgtgatcc ccacagtagt
      721 cctgacctac tacttgatgt ggacacactg aggagtcctc tagcccgact accacctgga
      781 atccgctggc cccggaggaa ccgcagctcg ctgcggcggc gttggctcca ccacctcacc
      841 agtgacccgc aggggcctcc caccctgagt ccggaggcct ctggaccagc caaccataat
      901 agaggcaatt acctgggatg cttcagtgag gagggccagg agagaactct gaagggagca
      961 gtgttttacg acttgagaaa gatgaccgtg tcacactgcc aggatgcctg tgctgagcgg
     1021 tcttatgtct atgctggctt ggaggctggt gcagagtgct actgtgggaa taggctgccg
     1081 gccacacgtg tcagcctgaa ggagtgcaat caggagtgca agggagagaa aggctccatg
     1141 tgcggggctg tgcgccggct ctctgtgtac agcgtggggc tgcagcagcc aggctccaag
     1201 aagcggcgca ctgccaccta ccgagggtgc ttcccactgc ctgagaatgt cacccacacc
     1261 ttctcctcct ccatgacaca ggccaacatg actgtggaga cgtgttctgg attttgttcc
     1321 cagaaagagt ttcctctggc catcctccga ggctgggatt gctattgtgc ctaccctacc
     1381 ccccagttca gcctgcggga tgctgtggat ggagcactgt gcagtcaggc cccagagaca
     1441 caagggctac ctggctactg tgaggtctac cagacacccg tgcaagacac ccggtgcaca
     1501 gacaggaagt tcctgcccga caagtctaag gtgtttgtgg ctctgtcgag cttccctgga
     1561 gctgggaaca catgggcaag gcacctgatc gagcacgcca ctggcttcta cacgggaagc
     1621 tactacttcg acggaaccct gtacaacaag gggttcaagg gtgagaagga ccattggcgg
     1681 agccggcgca ccatctgtgt gaagacgcac gagagtggcc ggagggagat tgagatgttt
     1741 gactcggcca tcctgctgat ccggaacccc taccggtccc tagttgctga attcaacagg
     1801 aaatgcgctg gacacttggg ctatgcccct gaccgcaatt ggaagagcaa agaatggccg
     1861 gagtttgtga atagctatgc ctcctggtgg tcctcacatg tcctagactg gctcaagtat
     1921 gggaagcggc tgctggtcgt gcactatgag gagctgcggc acagcctggt gcccacactt
     1981 cgggagatgg tggctttcct caatgtgtcc gtgagcgagg agcggcttct ctgtgtggag
     2041 aacaacaaag agggcagctt caggaggcgt ggccggcgcc ctcatgacca ggagcccttc
     2101 acccctgaga tgaaggactt gatcaatggc tatatcagga cagtggacca ggccttgcgt
     2161 gaccacaact gggctgggct gcccagagag tatgtgccca gatgataggc ccaccctgat
     2221 ttcctgctcc tgctgagatg cggttatacc agtgggctga acactgctct agtgcattga
     2281 tccatggacc cctgggaagc atgggggctg gcacacaggc agcagggtgt tcttgaaggg
     2341 gctgctttgt gtgcaggaga tctgaggcag cacaaggctt acccagaggg atgtgtatca
     2401 caggacactc cttgccggac acttacgcat cctcagacac acttagacat caccccattc
     2461 tcacagtgac cattttaatg tgcctaagcc acttgagtgg ggtgggtcag acactcccag
     2521 ctttgcacac acagacaaat ggacacacac acacacacac acacacacac aatgtgccag
     2581 agactgacta tctgcctcac acacgctcca ggctttggga gaccctgggt ttcctgggct
     2641 caattgggca caaattggct tttgggggcc cttggctctg ggatattgtg ctggggagac
     2701 actattgatc tgagtagtgc actgaggact ggaggtacat agacagactg ttgctgatgg
     2761 gtactgtatg accctgactg cttgtctgac atcccataaa tgtgtgtgct gtgacatcct
     2821 ggcactgcaa acaaaaaaaa aaaaaaaaaa
//
