LOCUS       NM_011719               4519 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus wingless-type MMTV integration site family, member 9B
            (Wnt9b), mRNA.
ACCESSION   NM_011719
VERSION     NM_011719.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4519)
  AUTHORS   Yano-Sakamoto,K., Kitai,Y., Toriu,N., Yamamoto,S., Mizuta,K.,
            Saitou,M., Tsukiyama,T., Taniuchi,I., Osato,M. and Yanagita,M.
  TITLE     Expression pattern of Runt-related transcription factor (RUNX)
            family members and the role of RUNX1 during kidney development
  JOURNAL   Biochem Biophys Res Commun 722, 150155 (2024)
   PUBMED   38795454
REFERENCE   2  (bases 1 to 4519)
  AUTHORS   Rinta-Jaskari,M.M., Naillat,F., Ruotsalainen,H.J., Ronkainen,V.P.,
            Heljasvaara,R., Akram,S.U., Izzi,V., Miinalainen,I., Vainio,S.J.
            and Pihlajaniemi,T.A.
  TITLE     Collagen XVIII regulates extracellular matrix integrity in the
            developing nephrons and impacts nephron progenitor cell behavior
  JOURNAL   Matrix Biol 131, 30-45 (2024)
   PUBMED   38788809
REFERENCE   3  (bases 1 to 4519)
  AUTHORS   Naillat,F., Deshar,G., Hankkila,A., Rak-Raszewska,A., Sharma,A.,
            Prunskaite-Hyyrylainen,R., Railo,A., Shan,J. and Vainio,S.J.
  TITLE     Calcium signaling induces partial EMT and renal fibrosis in a
            Wnt4mCherry knock-in mouse model
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (5), 167180 (2024)
   PUBMED   38653356
REFERENCE   4  (bases 1 to 4519)
  AUTHORS   Gao,G., Li,X., Jiang,Z., Osorio,L., Tang,Y.L., Yu,X., Jin,G. and
            Zhou,Z.
  TITLE     Isthmin-1 (Ism1) modulates renal branching morphogenesis and
            mesenchyme condensation during early kidney development
  JOURNAL   Nat Commun 14 (1), 2378 (2023)
   PUBMED   37185772
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4519)
  AUTHORS   Qiu,T., Huteckova,B., Seppala,M., Cobourne,M.T., Chen,Z.,
            Hovorakova,M., Buchtova,M. and Tucker,A.S.
  TITLE     Molecular profiling of the vestibular lamina highlights a key role
            for Hedgehog signalling
  JOURNAL   Development 150 (7) (2023)
   PUBMED   36971701
REFERENCE   6  (bases 1 to 4519)
  AUTHORS   Juriloff,D.M. and Mah,D.G.
  TITLE     The major locus for multifactorial nonsyndromic cleft lip maps to
            mouse chromosome 11
  JOURNAL   Mamm Genome 6 (2), 63-69 (1995)
   PUBMED   7767007
REFERENCE   7  (bases 1 to 4519)
  AUTHORS   Juriloff,D.M.
  TITLE     Genetic analysis of the construction of the AEJ.A congenic strain
            indicates that nonsyndromic CL(P) in the mouse is caused by two
            loci with epistatic interaction
  JOURNAL   J Craniofac Genet Dev Biol 15 (1), 1-12 (1995)
   PUBMED   7601909
REFERENCE   8  (bases 1 to 4519)
  AUTHORS   Biddle,F.G. and Fraser,F.C.
  TITLE     Major gene determination of liability to spontaneous cleft lip in
            the mouse
  JOURNAL   J Craniofac Genet Dev Biol Suppl 2, 67-88 (1986)
   PUBMED   3491126
REFERENCE   9  (bases 1 to 4519)
  AUTHORS   Juriloff,D.M.
  TITLE     Major genes that cause cleft lip in mice: progress in the
            construction of a congenic strain and in linkage mapping
  JOURNAL   J Craniofac Genet Dev Biol Suppl 2, 55-66 (1986)
   PUBMED   3491125
REFERENCE   10 (bases 1 to 4519)
  AUTHORS   Trasler,D.G. and Leong,S.
  TITLE     Mitotic index in mouse embryos with 6-aminonicotinamide-induced and
            inherited cleft lip
  JOURNAL   Teratology 25 (2), 259-265 (1982)
   PUBMED   7101202
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK052708.1, AL596108.13 and AL627252.16.
            
            On May 27, 2009 this sequence version replaced NM_011719.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052708.1, BC110482.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849379, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-865               AK052708.1         2-866
            866-3922            AL596108.13        2001-5057           c
            3923-4519           AL627252.16        137282-137878       c
FEATURES             Location/Qualifiers
     source          1..4519
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 67.47 cM"
     gene            1..4519
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /note="wingless-type MMTV integration site family, member
                     9B"
                     /db_xref="GeneID:22412"
                     /db_xref="MGI:MGI:1197020"
     exon            1..135
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1132
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /note="protein Wnt-9b; protein Wnt-14b; wingless-type MMTV
                     integration site family, member 15; wingless-type MMTV
                     integration site 15; wingless-type MMTV integration site
                     9B"
                     /codon_start=1
                     /product="protein Wnt-9b precursor"
                     /protein_id="NP_035849.3"
                     /db_xref="CCDS:CCDS25522.1"
                     /db_xref="GeneID:22412"
                     /db_xref="MGI:MGI:1197020"
                     /translation="MRPAPALALAALCLLVLPAAAAAAAYFGLTGREVLTPFPGLGTA
                     AAPAQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNC
                     SLEGRTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQ
                     WGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVS
                     GSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKGL
                     APRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDSSCSSLCCGRGYDTQSRMVVFSCH
                     CQVQWCCYVECQQCAQQELVYTCKR"
     exon            136..392
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            393..658
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            659..4519
                     /gene="Wnt9b"
                     /gene_synonym="clf; clf1; wnt-14b; wnt-15; Wnt14b; Wnt15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgagcgcct agtggcgcga ggagatgcga gagtgcaccg gccgcctgca ccatgcgccc
       61 cgcgcccgcg ctggccctgg ctgcgctctg cctgctggtg ctgcctgccg ctgccgccgc
      121 cgccgcctac ttcggcctga ccggtcgtga ggtcctgaca cccttcccag gcctgggtac
      181 ggcagcagcc ccggcacagg ctggtgctca cctgaagcag tgtgacctac tgaagctgtc
      241 caggcggcag aagcagctct gcaggcggga gcccggcctg gctgagaccc tgagggatgc
      301 tgcacacctg gggctgctgg aatgtcagtt ccagttcagg caggagcgct ggaactgcag
      361 cctggagggg aggactggcc tgctccagag aggctttaag gagacggcct tcctgtatgc
      421 agtgtctgca gctgccctca cgcatgcact ggccagggcc tgcagtgctg ggcgcatgga
      481 gcgctgtact tgtgacgact ccccaggcct ggagagccgg caggcctggc agtggggtgt
      541 gtgtggtgac aatctgaagt acagcaccaa gttcctcagc aacttcctgg ggcccaagag
      601 aggaagcaag gacctgaggg cgagggctga cgcccacaac acccacgtgg gcatcaaggc
      661 tgtgaagagc ggcctgagaa caacctgcaa gtgccatggt gtgtcaggct cctgtgctgt
      721 tcgtacctgt tggaagcagc tctccccgtt tcgcgagacc ggccaggtgc tgaagctacg
      781 ctatgacacg gctgtcaagg tgtccagtgc caccaacgag gccttgggtc gtctggagct
      841 atgggccccc gctaagccag gtggtcccgc caagggccta gcccctcgtc ccggggacct
      901 ggtctacatg gaagattctc ccagcttctg ccggcccagc aagtactctc cgggcacggc
      961 aggcagggtg tgttctcgag actccagttg cagcagccta tgctgtgggc gaggctacga
     1021 cacccagagc cgcatggtgg ttttctcctg ccactgtcag gtgcagtggt gctgctacgt
     1081 ggagtgccag cagtgtgcac agcaggagct cgtgtatacc tgcaagcgct aggcctccac
     1141 agcgaatccc gcggaacagc gcgcaagcgc gcacctgtcg acgcacctgc cgtgcacaag
     1201 agtgtgcgac tcatctctct tccccaacag atggttggcc agcccttctg ccttccccga
     1261 cactcagcaa agagaaagaa agccctgcct cctagtccca ggatcaccaa cctgctggag
     1321 gacttggggc cggagaacag actgagaagg ggaatctttg aggaccaggg tagggcagga
     1381 atgatgctgt gcgggaagag agaaacatcc tcctatctca aggccaaaaa ctgggaggat
     1441 ggggaagagg gaggcggagc cagctggagt gtggggtcag ggcatccatc tgggcgtggc
     1501 cgatctcttg tggtcccact ctaatagcag agcgctctgg gtgctgcatg cctaccctgc
     1561 tcttgtggct tcgtgcactg gagacttcga aatgtttatt aggagcaagg gaagcacttt
     1621 aggcttgggt ggattgagtc gcagagccca tgccctgaag tcttacgtcc tggcactcag
     1681 ggctgccacc ttgtctcctt gtcttgagat cccctgtccc ccaaagccat tgagctctgc
     1741 tcaacgagac ccctaatatg tataagaagg gtgcaggagc cagtctcctc ggtgagactc
     1801 agataaacat aactagggtt gagcggggag acagtgaccc tttctctttc ctttggtcca
     1861 aggaaccttt aatcacagcc cagaggtgga gagaggcagg gtccaaatgc ctggaagaga
     1921 tatgacaggc tctgtattga gataccactc tggagtgtgt cctaccaatt cctgtgacca
     1981 gggaccccca agaaccgagg ggcccccatc catgttagtg atacataaga acgagtgact
     2041 catgggccac acgtctgctt ccaccccctg ctctcaaaga tgcttgtgca ggcttttttg
     2101 ccattgctaa gtctttgcca agtctgcctc ctcaatggtc ttactcattt actaacgacc
     2161 tgtcacttgg gctcccacca gaggaacaaa atgactgctg gtgaatcctt tggtcatttt
     2221 taatgccccc atcaaggccc tctgtgagag gagaggaagt agtgtacagg tacaggctca
     2281 cacgtgcaca cactcagcct agccaggcac agacatccca aggagcagtg cggcgtctct
     2341 ccagcccagg gcaaagacct cactggggtc acttctggag gctgtgagct actccagggc
     2401 agggcccaag gccaaccagg aggaagtgac ctcctttggg aagcctttgg ccatgtggct
     2461 ggctgtgctg caccctcctg tgagcttcct tccaccctga aatctgttgg ggttactgtc
     2521 tctctaaggg agcaggaagc ttcggaatca gccggtactc agcactactg gccctgccag
     2581 ctccaggaaa gagacactgt ggcggagagg tccgtggggc agaaggggct accctttctt
     2641 cagtgcctcc gggcagcatg ctgggaagat ctttgatggt ggaaagcccc gaggcggagc
     2701 caccgtgacc tgagaccctt ctctgggacg actttgccac ccacccgcag cttggcagga
     2761 ggggtaaaca gattgggagc tgctttctac ttccctgatg aagacagatg tgttccttgg
     2821 caacccaagg catccttctc tatgacccta atcctgctct ggctcgaggg tacaaggcaa
     2881 gaatggagcc tggcaaaact tggggactag aacacctgga cctacagcca aatcacctgt
     2941 accctgactc tatggccagg agggccaggg gtggaggagg gttaaagatg aacttgaagt
     3001 tgaggctgag gctgaccaac cattaagact ggtgccttaa ggcaccctca gtcaggtcct
     3061 ctccctccct tctccattct ttctccaagg ccccgttccc cctaaaatcc caccatagcc
     3121 atgctgggtc cccccttccc ccacactgga actttaagga agatattcac agggtatttc
     3181 tgcctacctc atacatgtaa ttttcaaaaa aaattaattt atatagttaa gatatatggg
     3241 aaagtattta tgttatttat atatcttctc tatttcctgg gcaccatatg gggggttgtg
     3301 tgtttaccca gaagcctctg aggaaacatg gctgggtctg tctggggcct cgcagagctg
     3361 gatgcgcata gctgagaggt cacagctcct gtgtctcact gtcttggagc tcgggaagca
     3421 catgtacctc ctgagataaa ccccgtgaca ccaagcaggg ccttccttgt gaagtctgtg
     3481 gattctctgc ctctggcccc agaggccttt ctgctctggc ccaagggttt tgctcataaa
     3541 ggacaaaaag ggtgagcagc tctggatttg taaagcactt tccatcttca gaaacactcc
     3601 tctcttctct ctccctcggt tacccccggt tccctatgag gtcatgccac tgttaccacg
     3661 ttccaggccc agagacggag gcaggttggt caaagccagt cactctctga acccagaggt
     3721 tgaggaagag tgcatgctgc gtggaacgct ggtcttcccc catggatggc atgctagttt
     3781 ctccagcaag ctgagtctca tgtccccaaa gacggggact tcctgagaag cctggagaga
     3841 caagggctcc gtggatgtca ctcttaggga gggtgtcctg cagccctcat tgacctccac
     3901 gactaggcta tggtctccag cccctcacag ctcgtggata atttgtgttt cttcgctttt
     3961 gttttttgtc ttttcaaagt gactttttcc ccactggatt tctaagtttc tctttgaaaa
     4021 tcagttcact ggcaaatggg acctgcatcc tgacctggct gcctgcatca ggagcgacac
     4081 caaacagagt gcgtggggat ccccaattgg cccagtgtcc cccggccctt ccttaagtca
     4141 cacaagctcc cgtgtggctt tcgtgagcat ggagaacctg tcccctggtc ttagagaaag
     4201 ccagccattc tgccaccctc tgtttgtctg gcagacagat taccacaccg tggctgtctt
     4261 tctagccaaa gcttcctctc tcaacaccca tgaacgtcca tgcttcctgt ctgagcactg
     4321 aggagaaccc cagcggagct cattgttcag tgctggaata cccatccccc ctcccgttga
     4381 ttatttaggg agtgtctgat aatgccaggg gatactctgg gtgctagggc gcagaagtac
     4441 ttaagagcaa gtcccagcct caggggactt atatgccggc gaggagaaag ccaacaaacc
     4501 aataaactat gcactggtt
//
