LOCUS       NM_139298               3318 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus wingless-type MMTV integration site family, member 9A
            (Wnt9a), mRNA.
ACCESSION   NM_139298
VERSION     NM_139298.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3318)
  AUTHORS   Song,C., Sawall,J.K., Ji,X., Song,F., Liao,X., Peng,R., Ren,H.,
            Koyama,E., Pacifici,M. and Long,F.
  TITLE     Tgfbeta signaling stimulates glycolysis to promote the genesis of
            synovial joint interzone in developing mouse embryonic limbs
  JOURNAL   Sci Adv 11 (2), eadq4991 (2025)
   PUBMED   39772668
REFERENCE   2  (bases 1 to 3318)
  AUTHORS   Zhang,B., Zhao,C., Shen,W., Li,W., Zheng,Y., Kong,X., Wang,J.,
            Wu,X., Zeng,T., Liu,Y. and Zhou,Y.
  TITLE     KDM2B regulates hippocampal morphogenesis by transcriptionally
            silencing Wnt signaling in neural progenitors
  JOURNAL   Nat Commun 14 (1), 6489 (2023)
   PUBMED   37838801
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3318)
  AUTHORS   Iskusnykh,I.Y., Fattakhov,N., Li,Y., Bihannic,L., Kirchner,M.K.,
            Steshina,E.Y., Northcott,P.A. and Chizhikov,V.V.
  TITLE     Lmx1a is a master regulator of the cortical hem
  JOURNAL   Elife 12, e84095 (2023)
   PUBMED   37725078
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3318)
  AUTHORS   Zhang,C.H., Gao,Y., Hung,H.H., Zhuo,Z., Grodzinsky,A.J. and
            Lassar,A.B.
  TITLE     Creb5 coordinates synovial joint formation with the genesis of
            articular cartilage
  JOURNAL   Nat Commun 13 (1), 7295 (2022)
   PUBMED   36435829
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3318)
  AUTHORS   Simonson,L., Oldham,E. and Chang,H.
  TITLE     Overactive Wnt5a signaling disrupts hair follicle polarity during
            mouse skin development
  JOURNAL   Development 149 (22) (2022)
   PUBMED   36305473
REFERENCE   6  (bases 1 to 3318)
  AUTHORS   Guo,X., Day,T.F., Jiang,X., Garrett-Beal,L., Topol,L. and Yang,Y.
  TITLE     Wnt/beta-catenin signaling is sufficient and necessary for synovial
            joint formation
  JOURNAL   Genes Dev 18 (19), 2404-2417 (2004)
   PUBMED   15371327
REFERENCE   7  (bases 1 to 3318)
  AUTHORS   Qian,J., Jiang,Z., Li,M., Heaphy,P., Liu,Y.H. and Shackleford,G.M.
  TITLE     Mouse Wnt9b transforming activity, tissue-specific expression, and
            evolution
  JOURNAL   Genomics 81 (1), 34-46 (2003)
   PUBMED   12573259
REFERENCE   8  (bases 1 to 3318)
  AUTHORS   Akiyama,H., Chaboissier,M.C., Martin,J.F., Schedl,A. and de
            Crombrugghe,B.
  TITLE     The transcription factor Sox9 has essential roles in successive
            steps of the chondrocyte differentiation pathway and is required
            for expression of Sox5 and Sox6
  JOURNAL   Genes Dev 16 (21), 2813-2828 (2002)
   PUBMED   12414734
REFERENCE   9  (bases 1 to 3318)
  AUTHORS   Weidenfeld,J., Shu,W., Zhang,L., Millar,S.E. and Morrisey,E.E.
  TITLE     The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung
            epithelium
  JOURNAL   J Biol Chem 277 (23), 21061-21070 (2002)
   PUBMED   11914369
REFERENCE   10 (bases 1 to 3318)
  AUTHORS   Katoh,M.
  TITLE     Molecular cloning and expression of mouse Wnt14, and structural
            comparison between mouse Wnt14-Wnt3a gene cluster and human
            WNT14-WNT3A gene cluster
  JOURNAL   Int J Mol Med 9 (3), 221-227 (2002)
   PUBMED   11836627
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY327813.1, AB072311.1 and AL713994.15.
            
            On Jul 13, 2005 this sequence version replaced NM_139298.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK087490.1, AB072311.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BY327813.1         1-36
            37-658              AB072311.1         1-622
            659-3318            AL713994.15        103756-106415
FEATURES             Location/Qualifiers
     source          1..3318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.55 cM"
     gene            1..3318
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /note="wingless-type MMTV integration site family, member
                     9A"
                     /db_xref="GeneID:216795"
                     /db_xref="MGI:MGI:2446084"
     exon            1..138
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /inference="alignment:Splign:2.1.0"
     exon            139..395
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /inference="alignment:Splign:2.1.0"
     exon            396..658
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /inference="alignment:Splign:2.1.0"
     exon            659..3318
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3289..3294
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /note="hexamer: AATAAA"
     polyA_site      3310
                     /gene="Wnt9a"
                     /gene_synonym="wnt-14; Wnt14"
                     /note="major polyA site"
ORIGIN      
        1 gcggagcccg gagcgcgatg gtctgccgcc gcggcgcggc aagatgctgg atgggtccct
       61 tctggcgcgc tggctggccg cggccttcgg gctgacgctg ctgctcgccg cgctgcgccc
      121 ttcggccgcc tacttcgggc taacaggcag tgaacccctg actatcctcc ctctgaccct
      181 ggagaccgag gctgcggccc aagcacacta caaggcctgc gacaggctga agctggagcg
      241 caagcagcgc cgcatgtgcc gcagggaccc gggtgtggcc gagacactgg tggaggccgt
      301 aagcatgagt gccctggagt gccagtacca gttccgcttt gagcgctgga actgcaccct
      361 ggagggccgc taccgagcca gcctgctcaa gcgaggcttc aaggagactg ctttcctcta
      421 cgccatctct tctgccggcc tgacgcatgc actggccaag gcctgcagtg caggccgcat
      481 ggagcgctgc acgtgtgatg aggcacccga cctggaaaac cgcgaggcct ggcagtgggg
      541 cggctgcggg gacaacctca agtacagcag caagtttgtc aaggagttcc tgggccggcg
      601 ctctagcaag gatttgcgag cccgagtgga cttccacaac aacctcgtgg gtgtgaaggt
      661 gataaaggct ggagtggaaa ccacttgcaa atgccatggt gtgtctggct cctgcaccgt
      721 gcggacctgc tggcggcagc tagcaccctt ccacgaggtg ggcaagcacc taaaacacaa
      781 atatgagacc tcgctcaagg tgggcagcac taccaatgaa gccactggag aggcaggtgc
      841 catctcccca ccgcggggcc gggcttctgg gtcaggaggt ggcgacccac tgccccgaac
      901 accagagctt gtacacctgg acgactctcc cagcttctgc ctggctggcc gcttttcccc
      961 tggcacggca ggccgcaggt gtcaccggga gaagaactgt gagagtattt gttgtggccg
     1021 aggccacaac acacagagtc gtgtggtgac aaggccctgc caatgccagg tccgctggtg
     1081 ctgctacgtg gagtgcaggc agtgtacaca gagagaggag gtctatacct gcaagggctg
     1141 acccgaggcc ctgcagctcc accgcaagcg gtgtggactt tgcacacagc accagaagaa
     1201 ttctacacct gcaggagctg actccaacgg ccctgccagc ctttctgcag ggagtgtagg
     1261 ctttgcacat agtgcaaagg gtcttaatct gcatggagtg agccctgcag gtccagccta
     1321 tcctgctgtg tggggcacag ggttacaaac aacacagaag gtctacaagg atgaagaggt
     1381 gcccctagca cacttgggcc ctggtataca gacagccagt tggctgtctc tcggcccaga
     1441 gggcggggct ggcccctgtc tggcctcctc aacccttttg cttatgcctt gggcctgagc
     1501 ttggccccct gacccgagag cgttgcagta atgctttctc agttgcctct gtccctgaca
     1561 catcagtata gcccttgtca gggaccagca tgttgactgg ccctctgtgc ctcttggctt
     1621 cctctgaggc atggagggca ggtgcacctt cataatcgca tggctgccct tctggcccag
     1681 cagcctgatg ccagcactgt cttcttcaga gagccaaacc actaggagag ggcagccact
     1741 ccatccccag ggtgcagcct ccggccctct gaccctgagc acttccgtgg agtatcagtg
     1801 acttttaaat tattattatt atttaactaa tatagtaatt attattttcc ctgtcccctt
     1861 acctcctcat ctgtggcttt tccctctgag ctgccccagg cccagtcaag ccagtctggg
     1921 aggccttgcc ttccctctct tcatcgtccc cccctccttt gcttgctcta gtttgaaacc
     1981 actaaatcaa ggtcatgttt ggaaagaaat gaagcgatag agcctagcca tggcccacaa
     2041 ggcttctgga atccactccc caattctacc ttccccaggg tcagagaccc ttggtggtcc
     2101 ctgctctgtg ccctgcaggt gcagagatca ggttgctgga tatagatggg ggatttgggg
     2161 gtcctggagc catgggcacg gagacagggg cagggtcagc tttttgattg tccatctcag
     2221 gaagccattc ttgctctgtg tccccaaggg aggtatggag ggacagacac acttgctgtc
     2281 atcaggtctt gctgatgtct ctacagggga aaggtgacta cactgagctg gtgttgagtg
     2341 tgtgtgcagg agttgtgtga gtgtgtgagt gtgtgtatat tccgagctgg catggtcagc
     2401 atccagttgg cctgtgttcc ctctgcggta tggggactct ttggctccca gaaagcccag
     2461 ccttaggttt gtgggaaccc atggctgtgt gggttagagt gtgggcaggt ggcagagatg
     2521 acaacaggca ctactgagga aaggaccggc tatgtgtgcc ttggagcacc aggggtccag
     2581 aagacccaga cttggggggg ggtggggggt ggtgtcttaa aggaaaccta tttatgtgga
     2641 tgggggactc tggtccctat tggatgtgta aatagcaaag tttattctcc tgtggttcct
     2701 gtagcccact aatgaatgcc acgtttccag gatgtgagtg ggtggcagta tacagaggct
     2761 ggtgggcagg agtgtacccc ctacatctca gatgtctgta cccagtcaca cgaccaccac
     2821 agacgggagc ttcatctctt tcagttctgg ggaaaggagc ctaccagtcc agaggaagaa
     2881 tatttttatc gaattaccac atttagctct ctgtcctcaa tattcagaaa agtatttttt
     2941 ttaaaacaag gcagaatgaa aacgtctgcc ggctggtttg tttctgtata aatatatact
     3001 agaatgtctt tctggatgaa gcaactcccg caggccagag cctctttgat cttcttctat
     3061 gggcagcaga gtgagcagct gccctgctcc cgccggtcct gccggccacc caggttaagc
     3121 cggtacagca gtggactcac aagggagctg tctttgtgtg gagtcttgtg cagcctgtga
     3181 tttctctacc tcaactgtgt ggcgagtagg tgtgaacctg agtgactgca gagaatgtat
     3241 ttatttaaca gctttgtgta acaaaaccag aaacaaatgg aaacactaaa taaatgtatt
     3301 ttaaattata gacaacct
//
