LOCUS       NM_009290               1520 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus wingless-type MMTV integration site family, member 8A
            (Wnt8a), mRNA.
ACCESSION   NM_009290
VERSION     NM_009290.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Simonson,L., Oldham,E. and Chang,H.
  TITLE     Overactive Wnt5a signaling disrupts hair follicle polarity during
            mouse skin development
  JOURNAL   Development 149 (22) (2022)
   PUBMED   36305473
REFERENCE   2  (bases 1 to 1520)
  AUTHORS   Murphy,P., Armit,C., Hill,B., Venkataraman,S., Frankel,P.,
            Baldock,R.A. and Davidson,D.R.
  TITLE     Integrated analysis of Wnt signalling system component gene
            expression
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831952
REFERENCE   3  (bases 1 to 1520)
  AUTHORS   Garcia-Padilla,C., Dominguez,J.N., Lodde,V., Munk,R.,
            Abdelmohsen,K., Gorospe,M., Jimenez-Sabado,V., Ginel,A.,
            Hove-Madsen,L., Aranega,A.E. and Franco,D.
  TITLE     Identification of atrial-enriched lncRNA Walras linked to
            cardiomyocyte cytoarchitecture and atrial fibrillation
  JOURNAL   FASEB J 36 (1), e22051 (2022)
   PUBMED   34861058
REFERENCE   4  (bases 1 to 1520)
  AUTHORS   Zhang,R., Feng,Y., Lu,J., Ge,Y. and Li,H.
  TITLE     lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in
            Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a
            Axis
  JOURNAL   Invest Ophthalmol Vis Sci 62 (3), 13 (2021)
   PUBMED   33687475
  REMARK    GeneRIF: lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion
            Cells in Retinal Ischemia Reperfusion Injury by Targeting the
            miR-484/Wnt8a Axis.
REFERENCE   5  (bases 1 to 1520)
  AUTHORS   Ru,J., Guo,D., Fan,J., Zhang,J., Ju,R., Ouyang,H., Wei,L., Liu,Y.
            and Liu,C.
  TITLE     Malformation of Tear Ducts Underlies the Epiphora and Precocious
            Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for
            Tear Duct Genesis
  JOURNAL   Invest Ophthalmol Vis Sci 61 (13), 6 (2020)
   PUBMED   33141892
REFERENCE   6  (bases 1 to 1520)
  AUTHORS   Jaspard,B., Couffinhal,T., Dufourcq,P., Moreau,C. and Duplaa,C.
  TITLE     Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart
            morphogenesis
  JOURNAL   Mech Dev 90 (2), 263-267 (2000)
   PUBMED   10640709
REFERENCE   7  (bases 1 to 1520)
  AUTHORS   Niederreither,K., Vermot,J., Schuhbaur,B., Chambon,P. and Dolle,P.
  TITLE     Retinoic acid synthesis and hindbrain patterning in the mouse
            embryo
  JOURNAL   Development 127 (1), 75-85 (2000)
   PUBMED   10654602
REFERENCE   8  (bases 1 to 1520)
  AUTHORS   Studer,M., Lumsden,A., Ariza-McNaughton,L., Bradley,A. and
            Krumlauf,R.
  TITLE     Altered segmental identity and abnormal migration of motor neurons
            in mice lacking Hoxb-1
  JOURNAL   Nature 384 (6610), 630-634 (1996)
   PUBMED   8967950
REFERENCE   9  (bases 1 to 1520)
  AUTHORS   Bouillet,P., Oulad-Abdelghani,M., Ward,S.J., Bronner,S., Chambon,P.
            and Dolle,P.
  TITLE     A new mouse member of the Wnt gene family, mWnt-8, is expressed
            during early embryogenesis and is ectopically induced by retinoic
            acid
  JOURNAL   Mech Dev 58 (1-2), 141-152 (1996)
   PUBMED   8887323
REFERENCE   10 (bases 1 to 1520)
  AUTHORS   Bouillet,P., Oulad-Abdelghani,M., Vicaire,S., Garnier,J.M.,
            Schuhbaur,B., Dolle,P. and Chambon,P.
  TITLE     Efficient cloning of cDNAs of retinoic acid-responsive genes in P19
            embryonal carcinoma cells and characterization of a novel mouse
            gene, Stra1 (mouse LERK-2/Eplg2)
  JOURNAL   Dev Biol 170 (2), 420-433 (1995)
   PUBMED   7649373
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC074335.11.
            
            On Jan 14, 2019 this sequence version replaced NM_009290.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC119212.1, Z68889.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               AC074335.11        96259-96368
            111-144             AC074335.11        96454-96487
            145-283             AC074335.11        96776-96914
            284-409             AC074335.11        98714-98839
            410-552             AC074335.11        99434-99576
            553-1520            AC074335.11        101026-101993
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 18.69 cM"
     gene            1..1520
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /note="wingless-type MMTV integration site family, member
                     8A"
                     /db_xref="GeneID:20890"
                     /db_xref="MGI:MGI:107924"
     exon            1..110
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..1107
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /note="wingless-related MMTV integration site 8D; protein
                     Wnt-8a; wnt-8; stimulated by retinoic acid gene 11
                     protein; protein Wnt-8d; wingless-related MMTV integration
                     site 8A"
                     /codon_start=1
                     /product="protein Wnt-8a precursor"
                     /protein_id="NP_033316.2"
                     /db_xref="CCDS:CCDS29129.1"
                     /db_xref="GeneID:20890"
                     /db_xref="MGI:MGI:107924"
                     /translation="MGHLLMLWVAAGMCYPALGASAWSVNNFLITRPKAYLTYTASVA
                     LGAQIGIEECKFQFAWERWNCPEHAFQFSTHNRLRAATRETSFIHAIRSAAIMYAVTK
                     NCSMGDLENCGCDESQNGKTGGHGWIWGGCSDNVEFGEKISRLFVDSLEKGKDARALV
                     NLHNNRAGRLAVRASTKRTCKCHGISGSCSIQTCWLQLADFRQMGNYLKAKYDRALKI
                     EMDKRQLRAGNRAEGRWALTEAFLPSTEAELIFLEGSPDYCNRNASLSIQGTEGRECL
                     QNARSASRREQRSCGRLCTECGLQVEERRAEAVSSCDCNFQWCCTVKCGQCRRVVSRY
                     YCTRPVGSARPRGRGKDSAW"
     exon            111..144
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
     exon            145..283
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
     exon            284..409
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
     exon            410..552
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
     exon            553..1520
                     /gene="Wnt8a"
                     /gene_synonym="Stra11; Wnt-8A; Wnt-8D; Wnt8d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttctctgc gcttggtcct ggttcccgga ctgggcagga ccatgggaca cttgttaatg
       61 ctgtgggtgg ctgcgggcat gtgctatcca gccctgggtg cttctgcctg gtcagtgaac
      121 aacttcctga taacccgtcc caaggcctat ctgacctaca ccgccagtgt ggccttggga
      181 gctcagattg gcatcgaaga gtgtaagttc cagtttgcct gggaacggtg gaattgtcct
      241 gagcatgctt ttcagttttc aacccacaac aggctgcgag ctgccacgag agagacatcc
      301 ttcattcatg ccatccgctc tgctgccatc atgtacgcag tcaccaagaa ctgcagcatg
      361 ggtgacttgg aaaactgcgg ctgtgacgag tcacaaaatg gaaaaacagg tggccatggc
      421 tggatctggg gaggctgcag cgacaacgtg gagttcgggg aaaaaatctc cagactcttc
      481 gtggacagtt tggagaaagg gaaggatgcc agagccctgg tgaaccttca caacaacagg
      541 gccggcagac tggcagtgag ggcctccacg aaaaggacct gcaagtgtca tggcatctca
      601 ggaagctgca gcatccagac gtgttggctg cagctggctg acttccggca gatgggaaat
      661 tacctaaagg ccaagtatga ccgcgcgctg aaaattgaga tggacaagcg ccagctaagg
      721 gctggcaaca gagccgaggg ccgctgggct ctcacggagg ccttccttcc cagcacagag
      781 gctgagctga tcttcttaga ggggtctcct gactactgca accgcaacgc cagcctgagc
      841 atccagggca cagaggggag ggagtgcctg cagaatgccc gcagtgcttc ccggcgggag
      901 cagcgcagct gtgggcgcct gtgcacggag tgcgggctgc aggtggagga gaggagagca
      961 gaggccgtga gcagctgtga ctgcaacttt cagtggtgtt gcactgtcaa gtgtggccag
     1021 tgcaggcgtg tggtgagcag atactactgc acacgccctg taggtagtgc caggccccgg
     1081 ggcaggggca aggacagtgc ctggtaacac caccacaaat tcacgtgctg cctagttgca
     1141 ggacagtgga gatagagcct gaacttctgg cctaggggac acagactgga aaacaattgg
     1201 gacatcacag ggttggcctg tagaccttcc acgataggtg ggttagcctg tagaccttcc
     1261 acgataggcg gggtagatgg atgatcttta agcatcttct tcgcaggagt gaaatcggaa
     1321 ccttgttctc ctggcttgtg gacccagcct ttcctgcgca gttactcttg gacttaagca
     1381 gcttgttaaa gagggagttt gatttgggtg cacattcaga ggagcctgga agaaccgtat
     1441 tccattaagt ttcagatacc gttccaccca gctgtgctgc tgggagtgcg agggaagaga
     1501 agttaaagga aaggaattct
//
