LOCUS       XM_017314744            4233 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus WNK lysine deficient protein kinase 4
            (Wnk4), transcript variant X6, mRNA.
ACCESSION   XM_017314744
VERSION     XM_017314744.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000077.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_017314744.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4233
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="11"
     gene            1..4233
                     /gene="Wnk4"
                     /gene_synonym="2010002J11Rik; Pha2b; Prkwnk4"
                     /note="WNK lysine deficient protein kinase 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 18 ESTs, 28 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 22 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:69847"
                     /db_xref="MGI:MGI:1917097"
     CDS             888..3977
                     /gene="Wnk4"
                     /gene_synonym="2010002J11Rik; Pha2b; Prkwnk4"
                     /codon_start=1
                     /product="serine/threonine-protein kinase WNK4 isoform X6"
                     /protein_id="XP_017170233.1"
                     /db_xref="GeneID:69847"
                     /db_xref="MGI:MGI:1917097"
                     /translation="MKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSG
                     SVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEY
                     PYSECQNAAQIYRKVTSGTKPNSFYKVKMPEVKEIIEGCIRTDKNERFTIQDLLAHAF
                     FREERGVHVELAEEDDGEKPGLKLWLRMEDARRGGRPRDNQAIEFLFQLGRDAAEEVA
                     QEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKARELEVLPPDSGPPPATVSLA
                     PGPPSAFPPEPEEPEADQHQSFLFRHASYSSTTSDCETDGYLSSSGFLDASDPALQPP
                     GGLPSSPAESHLCLPSGFALSIPRSGPGSDFSPGDSYASDAASGLSDMGEGGQMRKNP
                     VKTLRRRPRSRLRVTSVSDQSDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYN
                     EFILPSERDGFLSRIREIIQRVETLLKRDAGPPEAAEDALSPQEEPAALPALPGPPNA
                     EPQRSISPEQRSWAAFSTSPSSPGTPLSPGAPFSPGTPPVFPCPIFPITSPSCYPCPF
                     SQVSSNPYPQAPSSLLPLSSSASQVPLPSSSLPISAPLPFSPSYPQDPLSPTSLPVCP
                     SPPSLPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPGPLPSLPLSLA
                     SCDQESLSAQTAETENEASRNPAQPLLGDARLAPISEEGKPQLVGRFQVTSSKEPAEP
                     PLQPASPTLSRSLKLPSPPLTSESSDTEDSAAGGPETREALAESDRAAEGLGVAVDDE
                     KDEGKEPLLGGSSPILSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQNLRQKH
                     LSEVEALQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSCRQRRLSKGSFPTSRRNSLQ
                     RSDLPGPGIMRRNSLSGSSTGSQEQRASKGVTFAGDIGRMVRGGPKEGRAEGMVAGSS
                     SAFLFFGHCFSIFLFPSSEFRPEVLCLPNTRAPPWPMASQNLMFFVTNSTQQRTPQH"
ORIGIN      
        1 ggtcgcgggg caggccagtc gggggctggg gccccagcag ctccgctgga gcgcggtgta
       61 cccagccggt ctgcctgtca ggcagcaacc tccagcctcc tggctttccg ttctgcggcg
      121 cctggccctt cccatgctag cacctcgaaa tacggagact ggggtcccca tgtcccaaac
      181 cgaggctgac ctggctctgc ggccatctcc ggctctcacc tctacggggc cgacccgcct
      241 ggggccacct cctcgccgag tgcgccgctt ctctgggaag gctgagcctc ggccgcgctc
      301 ttcgagacct agccgccgca gctcagtcga tctgggactg ctgagctcct ggtctcaacc
      361 agcctcactc cttccggaac ccccggatcc tccagactcc gctggcccca cgaggagccc
      421 accttcaagc tctaaagaac cccccgaggg cacatggatg ggggcagctc ccgtgaaggc
      481 tgtggactct gcatgtcctg agcttacggg atcttcagga ggtccagggt cccgggagcc
      541 accgagggtt cctgatgctg cagcccggga acggcggcgg gagcaggaag aaaaagagga
      601 cacagaaacc caggctgtgg caacgtctcc ggacggccga tacctcaagt ttgacattga
      661 gattggaaga ggttccttca agaccgtgta tcgagggcta gacaccgaca ccacggtaga
      721 ggtggcctgg tgtgagctgc agacccggaa actctctcgg gccgagcggc agcgtttctc
      781 cgaggaagtt gagatgctca aggggctgca gcaccccaac atcgtccgct tctatgactc
      841 ctggaagtcg gtgctgaggg gccaggtacc tgaggcggtt ccgcgaaatg aagccccgag
      901 tccttcagcg ctggagtcgc cagattctac ggggacttca tttccttcat tcccgagtgc
      961 cccccatcct gcaccgagat ctcaagtgtg acaacgtctt cattactggc ccttcaggct
     1021 ctgtcaaaat cggagacctc ggactggcca cgctcaagcg cgcctccttt gccaagagcg
     1081 tcattgggac cccggaattc atggctcctg agatgtacga ggaaaagtac gacgaggctg
     1141 tggatgtgta cgcctttggc atgtgcatgc tggagatggc tacgtctgag tatccctact
     1201 ccgagtgtca gaatgcagca caaatctacc gcaaggtcac ttcgggcaca aagcccaaca
     1261 gcttctacaa ggtgaagatg ccagaggtga aggagatcat tgaaggctgc atccgcacgg
     1321 ataagaacga gaggttcacc atccaggatc tcctggccca tgcgttcttc cgcgaggaac
     1381 gaggtgtgca cgtggagctg gcagaggaag atgatggaga gaagccgggc ctcaagctct
     1441 ggctgcgcat ggaggatgcg cggcgcgggg ggcgtccacg agacaaccag gccatcgagt
     1501 tcctgtttca gctcggccgg gacgctgcgg aggaggtggc tcaggagatg gtagccttgg
     1561 gcttagtctg tgaagctgac taccagccag tggcccgtgc agttcgagaa cgggttgctg
     1621 ctatccagcg gaagcgggag aagcttcgaa aagctaggga attggaggtt ctcccaccag
     1681 actcaggacc tcctccagca actgtgtctc tggctccggg tccccccagt gccttccccc
     1741 cagagcctga ggagccagag gctgaccagc atcaatcctt cctcttccgc catgccagct
     1801 actcatcaac tacatctgat tgcgagactg atggctacct cagttcctcc ggcttcctgg
     1861 atgcctcaga ccctgccctt cagccccctg gggggttacc atccagcccc gctgaatccc
     1921 atctctgctt gccctcgggt tttgccttgt ctattccacg gtctggccct ggcagtgact
     1981 tttctcctgg ggatagctac gcctcagatg cggcatcagg ccttagtgac atgggagaag
     2041 gggggcaaat gaggaaaaat ccagtgaaga ctcttcgacg gagacctcga tcccggctcc
     2101 gggtcactag tgtctcagac cagagcgaca gagttgtcga gtgtcagctg cagactcaca
     2161 acagcaagat ggtgacgttc cgatttgatc tggatgggga cagcccagaa gaaattgcag
     2221 ctgccatggt atacaatgag ttcatcctgc cctcggagcg agatggattc ctgagccgga
     2281 tccgggagat tatccagcga gtggagaccc tgctgaagag agatgctggt cccccagagg
     2341 ctgctgaaga tgccctgagc ccccaggaag agccagcagc cctgcctgcc ctcccaggcc
     2401 cacccaatgc agagccccag agaagcatct ccccagaaca gaggagctgg gcagccttct
     2461 ccacctctcc atcttctcct ggcaccccct tgtcccctgg ggcccccttt tcccctggga
     2521 cccctcctgt cttcccatgc cccatctttc ctatcacttc accctcatgc tatccctgcc
     2581 cattctccca ggtctcttca aacccctatc cacaggcccc cagttccctg cttcccttat
     2641 cctccagtgc ttctcaggtt ccacttccat cttcctctct tcccatcagc gctcccctcc
     2701 cattctctcc tagttatccc caagaccctc ttagccccac ttctcttccc gtctgcccct
     2761 ctcctccctc tcttccctct accacagcag cccctctcct ctctctggct agtgccttct
     2821 ctctggctgt gatgactgtg gcccagtccc tgctgtcccc atcccctgga cttctttctc
     2881 agtctcctcc agcccctcca ggtcctctgc ctagcctgcc cctttccctt gcttcttgtg
     2941 accaggagag cctttcggcc caaacagctg agacagagaa tgaggcttcc cgtaatcctg
     3001 ctcagccact actgggtgat gctagactgg cacctatatc tgaagaggga aagccccagc
     3061 ttgttggccg tttccaagtg acttcatcta aggaaccagc agagcctccc ctgcaaccag
     3121 catccccaac tctctccaga tccctaaagc tgccaagccc tccgctgacc tcagagagct
     3181 cagacacaga ggacagtgct gcaggaggcc cagagactag ggaggctctg gcagagagtg
     3241 accgtgcagc cgaaggcctg ggggttgcgg tcgatgatga aaaggatgaa gggaaggaac
     3301 ccctacttgg aggcagttcc ccaatcttga gccatcccag cccagtgtgg atgaactact
     3361 cctacagcag cctgtgtctg agcagtgagg agtcggagag cagcggggaa gacgaggaat
     3421 tctgggctga gctgcagaac cttcggcaga agcacttgtc ggaagtggag gcactacaga
     3481 cactacagaa gaaggaaatc gaggacttat acagccggct tgggaaacag cccccacctg
     3541 gtattgtagc tccagctgct atgctgtcct gccgccagcg ccgcctctcg aagggcagct
     3601 ttcccacctc ccgccgcaac agcctgcagc gctctgatct ccctggtcct ggcatcatgc
     3661 gaaggaactc tctgagtggc agcagcaccg gctcccagga gcagcgggca agcaaggggg
     3721 tgacattcgc cggggatatt ggcaggatgg tgaggggcgg gcccaaggaa gggagagccg
     3781 agggcatggt ggctggcagc agctctgcct tcctcttctt tggacattgc ttcagcattt
     3841 ttcttttccc ctccagtgaa ttcagaccag aagtcctatg tctccccaac accagggccc
     3901 caccatggcc catggcctct cagaatctga tgttttttgt gaccaactca actcagcaaa
     3961 gaacacccca gcactgagtg ggtagaaggc ccgtgggcac ggagagtgcg ttgtgttgta
     4021 tcctgaagag tcaaaacctt gcgggttctc tttgctgtgt ggaaatctca tttctgtagc
     4081 ctaccccacc tgccctcccc aggcaagggc tgaccactaa gcaatccgag tccagatgct
     4141 tgcggaaggc caacttccag ctgggagagt ggaggggctg tgctcctgcc accaaagtca
     4201 acagcaacca ataaaaatac tgaggagaaa ggc
//
