LOCUS       XM_011244419            8185 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus WNK lysine deficient protein kinase 2
            (Wnk2), transcript variant X5, mRNA.
ACCESSION   XM_011244419
VERSION     XM_011244419.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000079.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_011244419.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8185
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="13"
     gene            1..8185
                     /gene="Wnk2"
                     /gene_synonym="1810073P09Rik; ESTM15; mKIAA1760"
                     /note="WNK lysine deficient protein kinase 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 90 ESTs, 608 long SRA reads, 17 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:75607"
                     /db_xref="MGI:MGI:1922857"
     CDS             274..6924
                     /gene="Wnk2"
                     /gene_synonym="1810073P09Rik; ESTM15; mKIAA1760"
                     /codon_start=1
                     /product="serine/threonine-protein kinase WNK2 isoform X5"
                     /protein_id="XP_011242721.1"
                     /db_xref="GeneID:75607"
                     /db_xref="MGI:MGI:1922857"
                     /translation="MDGDGGRRDAPGALMEAGRGTGSAGMAEPRARAARLGPQRFLRR
                     SVVESDQEEPPGLEAAETPSAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAAPA
                     APPGSPSVPSDPGPERAGTQEPSPDPTTASAAAAQVPDGGPRQEEAPAPTQEDAGTTE
                     AKPEPGRARKDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETW
                     VEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTE
                     LMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGP
                     TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATS
                     EYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSH
                     AFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPD
                     EVAQEMIDSGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQSQEPKDSGSPDKARG
                     LPAPLQVQVTYHAQSGQPGQPEPEEPEADQHLLPPTLPASVTSLASDSTFDSGQGSTV
                     YSDSQSSQQSMVLSSLVDTAPTPASCVCSPPVSEGPGLTHSLPTLGAFQQPATVPGLS
                     VGPVPPPARPPLLQQHFPESSMSFTPVLPPPSTPVPTGPSQPAPPVQQPLPMAQPPTL
                     PQVLAPQPMGTVQPVPSHLPPYLAPTSQVVAPAQLKPLQMPQPPLQPLAQVPPQMPQM
                     PVVPPITPLTGLDGLPQTLTDLPAANVAPVPPPQYFSPAVILPSLTTPLPTSPALPMQ
                     AVKLPHPPGTPLAVPCQTIVPNAPAAIPLLAVAPQGVAALSIHPAVAQIPAQPVYPAA
                     FPQMVPGDIPPSPHHTVQSLRATPPQLASPVPPQPVQPSVIHLPEQAAPTAASGTQVE
                     LFMCCTHVEVRGQLAEVDFLLLPCGSRGSNSGHQVLLGHPPSYTADVAAPVSAVSLPP
                     AVLSPPLPDTLLPTVPDLLPKVPSSLAPTVVAASQSAPAQTSSLLLPTNPPLPTGPAV
                     AGPCPAVQLMVEVAQEEQVSQDKPPGPPQSSESFGGSDVTSGRDLSDSCEGTFGGGRL
                     EGRTARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDL
                     DGDAPDEIATYMVEHDFILPAERETFIEQMKDVMDKAEDMLSEDTDADHGSDTGTSPP
                     HLGTCGLATGEENRQSQANAPVYQQNVLHTGKRWFIICPVAEHPATDTSESSPPLPLS
                     SLQPEASQDPAPYPDQLSLTDKPSFPAAQQLLSQAGSSNPPGGASAPLAPSSPPVTTV
                     IPAAPATSTVPESAAGTAMQAGGPGTHQGPASVHETLQPLAETRSAQCTAQPLSTGQG
                     PCTPALEASRCSTGLGEPISTREVSTQGEPLPASVPEPSPPTGATQSVPGQPPPPLPI
                     TVGAISLAAPQLPSPPLGPTAPPPPPSALESDGEGPPPRVGFVDNTIKSLDEKLRTLL
                     YQEHVPTSSASAGTPMEASDRDFTLEPLRGDLPSALSDKTPSLTQQTQPSLEKSETAP
                     AGWALAQREQGASSPMTAESSSSNTLGCDSDAGQVASDSSTAPSVPQDASGSSVPTHM
                     DPKDQNSSVPREALAAPMQSGPGSFTVGSPAQLRGARDSGSPHKRPGQQDNSSPAKTV
                     GRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEIPSSPEVKLAVRRVQTASSIEVGVEE
                     PASSDSGDERPRRRSQVQKQSSLPGTGGVASDFVKKATAFLHRSSRAGSLGPETPSRA
                     GVKVPTISITSFHSQSSYISSDNDSEFEDADIKKELRSLREKHLKEISELQSQQKQEI
                     EALYRRLGKPLPPNVGFFHTAPPMGRRRKTSKSKLKAGKLLNPLVQQLKVVASSTGHL
                     SDSSRGPPTKDPAHASTPPGTKAVQTQQPCSVRASLSTDICSGLASDGGGARGQGSAL
                     KRLCLGKEHSSRSSTSSLAPGPEPGPQPTLHVQAQVNNSNNKKGTFTDDLHKLVDEWT
                     TKTVGAAQVKPTLNQLKQTQKLHDMEASGDARATSVPRAAVGASCLAPAPGPLSTTAT
                     PGATPALPVPIPGTVHSSLSGPPCTLPLCQYGGLLPDPVSWGPWVASGNPEGSWGSQS
                     PTQVPVFPVFLRPPVISTPGPRLHIT"
ORIGIN      
        1 gccccgccct ccccgcgcgc tagttcggag ccggtgcggg agcggaggcg cgcggagccg
       61 gcaggagcac gcgggagcgc ggccccgcag cggcccggcc cgagggagca gcatcgtagg
      121 agcagaacgg cctggcgacc cccgctgcag ccaggacccc gccccagcgc gacgcggccc
      181 cgagagagga ctctggcccc ggagcgcggc ctcgccctcc tcgctcgccc gggtccccgg
      241 gctgcgggca tggacagcgc ccgctcgccc tagatggacg gcgatggcgg ccgccgagac
      301 gcccccggcg cgctgatgga agccgggcgc ggcacggggt cggcgggcat ggcggagccg
      361 cgggcgaggg cggcgcggct cgggccccag cgcttcctgc ggcgcagcgt ggtggagtcg
      421 gaccaggagg agccgccggg cctggaggcg gccgagacgc cgagcgcgca gcccccacag
      481 cctctgcagc gcagggtgct tctactctgc aagacgcgcc ggctcatcgc ggagcgcgcc
      541 cggggccgcc ccgccgcgcc cgcgcccgcc gcgcccgctg cgcctcccgg ctccccgagt
      601 gtcccctcgg accctggccc ggagcgagcg ggcacgcagg agcccagccc agatcccacc
      661 accgcctcag ccgcagccgc gcaggtcccc gacggcggcc cgaggcagga agaggcgccg
      721 gccccaacac aggaggacgc tggaaccacc gaggcaaagc cggagcccgg gcgcgcacgc
      781 aaggatgaac ctgaagagga ggaagacgat gaggacgacc tcaaggccgt ggccacctct
      841 ttggacggcc gcttcctcaa gttcgacatc gagctgggcc ggggctcctt caagacggtc
      901 tacaaggggc tggacacgga gacctgggtg gaggtagcat ggtgtgaact gcaggaccgg
      961 aagctcacca agcttgaacg gcagagattc aaagaggagg cggagatgct gaaaggtcta
     1021 cagcacccca acattgtgcg cttctatgac ttctgggagt ccagtgccaa gggcaagcga
     1081 tgtatcgtgc tggtgacaga gctgatgacc tcgggtacac tgaagacgta cctgaagcgg
     1141 ttcaaggtga tgaagccgaa ggtactgagg agctggtgcc ggcagatcct gaagggcctg
     1201 ctgttcctgc atacaaggac accccccatc atccaccgtg acctcaagtg tgacaacatc
     1261 ttcatcactg ggcccaccgg ctctgtgaag attggtgact tgggtctggc cacccttaaa
     1321 agagcgtctt ttgccaaaag tgtgataggt acccccgagt tcatggcacc tgaaatgtac
     1381 gaggaacatt acgacgagtc ggttgatgtc tacgccttcg ggatgtgcat gctggaaatg
     1441 gctacctcag agtaccccta ttcggagtgc cagaacgccg cccagatcta tcgcaaggtc
     1501 acctgtggca tcaaaccggc cagcttcgag aaggtgcatg atccggagat taaggagatc
     1561 atcggggagt gcatctgtaa gaacaaagag gagaggtatg agattaagga cctgctgagc
     1621 catgccttct tcgcggaaga cacgggtgtc cgggtggaac ttgccgagga ggaccatggc
     1681 aggaagtcta ccatagccct gcggctttgg gtggaagacc ccaagaagct gaagggcaag
     1741 cccaaagaca atggagccat agagtttacc tttgacttgg agaaggagac tcccgacgag
     1801 gtggcccagg aaatgatcga ttctggattt ttccatgaga gtgatgtgaa gattgtggcc
     1861 aagtccatcc gtgaccgggt ggcactgatt cagtggcggc gtgagaggat ctggcctgca
     1921 ctgcagtctc aggagccaaa ggactctggc agccctgaca aggccagggg tctgccagca
     1981 cccctgcagg tccaggtgac ctaccacgca cagagtgggc agcctgggca gccagaacct
     2041 gaggagcctg aggccgacca gcatctcctg ccccctacct tgccagctag cgttacctcc
     2101 ttagcctcgg acagcacctt tgacagtggc cagggctcta ccgtgtactc ggactcccag
     2161 agcagccagc agagcatggt gctcagctcg cttgtggaca cggccccaac cccagcctcg
     2221 tgcgtgtgca gcccccctgt gagtgagggg cctggcctga cccacagcct gcctacgcta
     2281 ggggccttcc agcagccggc cactgtgcct ggcctgtctg tgggccctgt gccaccccct
     2341 gcccgccctc cactcctcca gcagcatttt ccagaatctt ccatgagctt cacccctgtg
     2401 ctgccaccac ccagcacccc tgtgcccacg ggcccaagcc agccagcacc cccagtccag
     2461 cagcctcttc caatggccca accacctacc ctgccacagg tcctggcccc acagcccatg
     2521 ggcactgtcc agccagtacc ctctcatttg cctccatacc tggctccaac ctcccaggtc
     2581 gtggcccctg ctcagctgaa gcctctccag atgccacagc cacctctgca acctcttgct
     2641 caagtccctc cgcagatgcc tcagatgcct gtggtccccc ccatcacccc cttaacagga
     2701 ctcgatggcc tccctcagac cctcactgac ctgccggccg caaacgtggc ccccgtgcca
     2761 ccacctcagt atttctcacc tgctgtgatc ttgccaagcc tcacaacacc cctgcccaca
     2821 tcaccggccc tgcctatgca ggctgtcaag ttgcctcatc cccctggaac acccctggct
     2881 gtgccctgtc agaccatcgt gccaaatgca ccagctgcta tccccctgtt ggccgtggcc
     2941 ccgcagggtg tggctgcact gtctatccat ccagcggtgg cccagatccc agcccagcct
     3001 gtgtacccag cagcctttcc acagatggta cctggagaca tcccaccctc accccaccac
     3061 acggtgcaga gcttacgggc cacccctcca cagctggcct cacctgtgcc tcctcagcct
     3121 gtccagccca gtgtcattca tctacctgag caggctgctc caactgctgc ctcagggacc
     3181 caggtggagt tgttcatgtg ttgtacacat gtagaggtca gaggacaact tgcagaagtt
     3241 gattttctcc tcctaccgtg tgggtcccgg ggatcaaact caggtcatca ggtcctgctg
     3301 ggccaccctc cttcatacac cgcggacgtt gctgctccag tctctgctgt gtccctgccg
     3361 cctgctgtcc tttcccctcc tctgccagat actctgctgc ctactgtccc tgacctcctg
     3421 cccaaggtcc ccagctctct ggcccctaca gtggtcgcag cctctcagag tgcgcccgca
     3481 cagacctctt cactcctcct gccaacaaac ccacccctgc ccactgggcc tgcagttgct
     3541 ggcccctgcc ctgcagtcca gctgatggtg gaagtggctc aagaggagca ggtctcacaa
     3601 gacaaacccc ctggcccccc acagagctcc gagagctttg gaggttctga tgtcacctct
     3661 ggaagagatc tgagtgacag ctgtgaaggc acctttggag ggggcaggct ggagggaagg
     3721 accgcccgga aacaccaccg taggtccact cgtgcacgct cgcggcagga gagggccagc
     3781 cggccccggc tcactatcct aaatgtgtgt aacacggggg acaagatggt ggagtgtcag
     3841 ctggaaacgc ataaccataa gatggtgacc ttcaagtttg acctcgatgg ggacgctccg
     3901 gatgagattg ccacgtacat ggtagagcat gactttatcc tgcccgctga gcgagagacc
     3961 ttcatcgagc agatgaagga tgtcatggac aaggcagaag acatgctcag tgaggacaca
     4021 gatgctgacc atggctctga tacagggacc agccctccac acctgggtac ctgtggtctg
     4081 gccacggggg aggagaacag acagtcccaa gccaatgccc ctgtctacca gcagaatgtc
     4141 ttacacacgg gaaagaggtg gtttatcatc tgtccagtgg ctgaacaccc agcaacagac
     4201 acttctgaat catcaccccc acttcctcta agctccttgc agccagaagc cagccaagac
     4261 ccagcgccct atccagacca gctgtccttg acggacaaac ctagtttccc agctgctcag
     4321 cagctcctga gccaggcagg ctccagcaac cctcctggtg gagcatcagc ccccttggcc
     4381 ccgtcttccc ctcctgtgac tactgtaatc ccggcagcac cagccaccag caccgtgcca
     4441 gagtcagcag cagggactgc catgcaggca ggaggtccag ggactcatca aggaccagcc
     4501 agtgtccatg agaccctcca gccactggcc gagacacgct ctgcccagtg tactgcccag
     4561 ccccttagta ctggccaagg accttgcacc ccagctctgg aagcctctcg ctgctccaca
     4621 ggtctggggg agcccatctc aaccagggag gtcagcactc aaggagagcc cctgcctgct
     4681 tcagtgccag aacctagccc tcccactggg gccacacaat ctgtaccggg tcagccacca
     4741 cccccactgc ccatcacagt aggggctatc agtctggcag ctccccagct ccccagtccc
     4801 cccctgggac ctactgctcc cccaccaccc ccctcagcct tggaatctga tggggaaggg
     4861 ccgcccccta gggtgggctt cgtggacaac accatcaaga gtctggatga gaaactgcgg
     4921 actctgctct accaggagca cgtgcccacc tcctcagcct cagctgggac ccccatggag
     4981 gcaagcgata gagacttcac cctggagccc ctgcgaggag accttccctc agccttgagt
     5041 gacaagaccc caagcctcac ccagcagacc cagccctcat tggaaaagtc tgaaacggcc
     5101 cctgcaggat gggccctggc ccagagggaa cagggtgcat cttctccaat gacagcagag
     5161 tcatcttcca gcaatacact gggctgtgac agtgacgcag ggcaggtggc ctcggactcc
     5221 tccacagcac ccagtgtccc ccaggatgcc tctggttctt ccgtccctac acacatggat
     5281 cccaaagatc agaacagtag tgttcccaga gaagccttgg cagcacccat gcaaagtggc
     5341 ccagggtcct tcacagtggg cagcccagcc cagctgcgtg gcgcccggga ctccgggtct
     5401 cctcataagc ggccagggca gcaggacaac agttctccag ccaaaactgt agggcgcttt
     5461 tccgtggtca gcacacagga cgagtggact ctggcgtcac ctcacagcct gcggtactct
     5521 gccccacccg atgtctacct ggatgagatc ccctctagcc ctgaggtgaa gctggcagtg
     5581 cggcgggtac agacagcctc ctccatcgag gttggcgttg aggaacctgc ctctagtgac
     5641 tctggggatg aacgcccaag aaggaggtcc caggtgcaga agcagtcctc cctgccgggt
     5701 actggtggtg tggcaagtga ctttgtgaag aaggccactg ccttcctgca caggtcttca
     5761 agggctggct cgctgggacc tgagacaccc agtagggcag gtgtgaaggt ccctaccatc
     5821 agcatcacct ccttccactc ccagtcatcc tacatcagca gtgacaatga ctcagagttt
     5881 gaggatgcag acataaagaa ggaactgcgc agtctgcgag aaaagcacct gaaggaaatc
     5941 tcggagctac agagccagca gaagcaggag atcgaagccc tgtaccgacg cttgggcaag
     6001 ccgctccctc ccaatgtggg gttcttccac actgcacccc ctatgggccg caggaggaaa
     6061 accagcaaga gcaaattgaa ggctggcaag ctgctgaacc ccttggtgca acagctcaag
     6121 gtcgtggcct ccagcacagg tcatttgtct gactccagca gaggccctcc cactaaggac
     6181 cctgcccacg ccagcacgcc cccgggcacc aaggcagttc agacccagca gccctgctcc
     6241 gttcgggcct ctctgtccac agacatctgc tccggtttag ccagtgatgg aggcggagcg
     6301 cgtggccaag ggtcagccct gaagcgtctc tgcctaggca aagaacacag cagtaggtct
     6361 tccaccagca gcctggcccc aggccctgag ccaggtcccc agcccaccct gcacgtccag
     6421 gcgcaggtga acaacagcaa caacaagaaa ggcaccttca cggacgacct gcacaagttg
     6481 gtggacgagt ggacaacgaa gaccgtgggg gcagcgcaag tgaagcccac gctcaaccag
     6541 ctgaagcaga cgcagaagct gcacgacatg gaggcctctg gagacgctcg ggctacatct
     6601 gtgcctcgag cagcagtggg ggcatcgtgt ctggccccgg cccctggccc tctgtccacc
     6661 acagccactc ctggagccac tccagccctg cctgtgccca taccaggtac tgtccactcc
     6721 agcctctcag gccctccttg tacactgcct ctatgtcagt atggaggcct gctccctgat
     6781 cctgtgtcct ggggaccctg ggtggcctca ggaaacccag aagggtcttg gggcagtcag
     6841 agccccactc aggtccctgt gttcccagtg tttctacggc cacctgttat cagcacacca
     6901 ggcccccggc tgcacatcac gtagcctcct gccctgccct gcccctggcc aaatggaaca
     6961 ctctgaagcg tgtagaagaa cccagttgtg gtttggcctc ctcatggctc ctccacatgg
     7021 gcacaaggca cagagcccca gcccaggggg catgagaggg cagcaagaca ctttccctgc
     7081 tgcctcagac cccgtcactc ttaggttcct gcagtctaca gaggcagtcc tcacacccag
     7141 ggcctgccct tgttagagga ttagaacctt gtcatcccct gcagcagctc agtgccttga
     7201 atcccagctt ttctgtttcc atgatggaaa tacatgtttt aaaaggccat tcatccgcaa
     7261 aagcggattc cattacagtg gcatgcgtat ggctgtctcc actgtgttat gttgtagagg
     7321 tgggaattgg gtacagatat gaagctggta actagtgaga gtgtaaaagc cttctataca
     7381 gaaacaaagg gaacactgac aatgtgacct ggaaatgctg gttaggtcca gctcagtcct
     7441 tgatagagcg aggtcaccct gggtgtcttc agtaacagag ccaccacgag gtttacctga
     7501 agttgttctc cctgtgagga gtgtcaccag ctttgttgag ccgtgaggat cctgccaggt
     7561 gaataccctg atagccagca ggctgttgta agcaccatac agacaaacat gaccttccag
     7621 ctcaggggcc ccactcactc tctccctctt ttccatggtt ttcagaggcc tgtgctctgc
     7681 ccaccccacc ctgcaaattc ctctccaggc catcctcagg ccagcctact gaggggcgga
     7741 gcatttctgg aggtttccat gacacttgcc ctggggggga gcggggagat gaaaactccc
     7801 tgaccccctc tgggtgaata ttttctgcct ccagttggag ggtgggctgc ctggggtgac
     7861 ccccgctgtg aactgtacag atcagatgta cccaggagaa gcagctagat tatttcggtt
     7921 taaatacact actccatcaa ttcagtcaga attgaatttc caggggactg cagaggcttc
     7981 tccctggccg caatgctgca ataagagatt tctgttctct gtgtcttagt ctcaacacca
     8041 cacaggccca ttcagtaaag cggagcctac gtcgtcttgc tcctcttgtg cccaagtcct
     8101 ttcctcctgt gacaatgcta gtggcatggg atccccaaga gtctgtatgt gtgaaggaga
     8161 aaaataaaca tttgcttgaa aatac
//
