LOCUS       NM_145940               1817 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat domain, phosphoinositide interacting 1
            (Wipi1), mRNA.
ACCESSION   NM_145940
VERSION     NM_145940.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1817)
  AUTHORS   Tzimas,C., Rau,C.D., Buergisser,P.E., Jean-Louis,G. Jr., Lee,K.,
            Chukwuneke,J., Dun,W., Wang,Y. and Tsai,E.J.
  TITLE     WIPI1 is a conserved mediator of right ventricular failure
  JOURNAL   JCI Insight 5 (11), 122929 (2019)
   PUBMED   31021818
  REMARK    GeneRIF: WIPI1 is a conserved mediator of right ventricular
            failure.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1817)
  AUTHORS   Akinduro,O., Sully,K., Patel,A., Robinson,D.J., Chikh,A.,
            McPhail,G., Braun,K.M., Philpott,M.P., Harwood,C.A., Byrne,C.,
            O'Shaughnessy,R.F.L. and Bergamaschi,D.
  TITLE     Constitutive Autophagy and Nucleophagy during Epidermal
            Differentiation
  JOURNAL   J Invest Dermatol 136 (7), 1460-1470 (2016)
   PUBMED   27021405
REFERENCE   4  (bases 1 to 1817)
  AUTHORS   Devereaux,K., Dall'Armi,C., Alcazar-Roman,A., Ogasawara,Y.,
            Zhou,X., Wang,F., Yamamoto,A., De Camilli,P. and Di Paolo,G.
  TITLE     Regulation of mammalian autophagy by class II and III PI 3-kinases
            through PI3P synthesis
  JOURNAL   PLoS One 8 (10), e76405 (2013)
   PUBMED   24098492
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1817)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL732387.10
            and AL645791.14.
            
            On Nov 17, 2006 this sequence version replaced NM_145940.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC025560.1, AK159608.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AL732387.10        67010-67166
            158-240             AL732387.10        72432-72514
            241-410             AL732387.10        74557-74726
            411-507             AL732387.10        81200-81296
            508-605             AL645791.14        192189-192286       c
            606-698             AL645791.14        191169-191261       c
            699-769             AL645791.14        190221-190291       c
            770-877             AL645791.14        189466-189573       c
            878-1042            AL645791.14        186721-186885       c
            1043-1150           AL645791.14        185385-185492       c
            1151-1269           AL645791.14        184669-184787       c
            1270-1370           AL645791.14        184151-184251       c
            1371-1817           AL645791.14        180615-181061       c
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 72.18 cM"
     gene            1..1817
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /note="WD repeat domain, phosphoinositide interacting 1"
                     /db_xref="GeneID:52639"
                     /db_xref="MGI:MGI:1261864"
     exon            1..157
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1418
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /note="WD40 repeat protein Interacting with
                     phosphoInositides of 49kDa; WIPI-1; WIPI 49 kDa; WD40
                     repeat protein interacting with phosphoinositides of 49
                     kDa"
                     /codon_start=1
                     /product="WD repeat domain phosphoinositide-interacting
                     protein 1"
                     /protein_id="NP_666052.1"
                     /db_xref="CCDS:CCDS25582.1"
                     /db_xref="GeneID:52639"
                     /db_xref="MGI:MGI:1261864"
                     /translation="MEAEAADAPPGRVEAALSCFSFNQDCTSLAIGTKAGYKLFSLSS
                     VEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSN
                     ILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTVLDIPSNPTGLCALSINHSNSYLAYP
                     GSQSTGEIVLYDGNSLKTVCTIAAHEGTLAAITFNSSGSKLASASEKGTVIRVFSVPE
                     GQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKMEHLTDSRPEEPSTWS
                     GYMGKMFMAATNYLPAQVSDMMNQDRAFATGRLNFSGQKNICTLSTIQKLPRLLVASS
                     DGHLYIYNLDPQDGGECVLIKTHSLLSSGTTEENKENDLRPSLPPSYAATVARPSTSA
                     ASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGSQKGKTKQS"
     exon            158..240
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            241..410
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            411..507
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            508..605
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            606..698
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            699..769
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            770..877
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1042
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1150
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1269
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1370
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1817
                     /gene="Wipi1"
                     /gene_synonym="4930533H01Rik; D11Ertd498e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccacggagcc ggcgcgggcg ggctgctgag gtggctgtcc cccgctcaga gctgcggctt
       61 ctcgggtcga gcccccgatg gaggccgaag ccgcagatgc ccctccgggc cgagtggagg
      121 cggcgctcag ctgcttctct ttcaaccaag actgcacatc cctagcgatt ggaaccaagg
      181 ccggttacaa gctgttttct ctgagttctg tggagcagct tgaccaagtc catggaagca
      241 atgaaatccc tgacgtgtat atcgtggagc gcctcttctc cagcagcctg gttgtagtgg
      301 tcagtcacac aaaacctcgg cagatgaacg tctaccattt caagaaaggc actgagatct
      361 gtaattacag ctactccagc aacattttgt ctattcggct caaccgacag aggctgctgg
      421 tctgcctgga agaatccatc tatatccaca acattaagga tatgaagtta ttgaagaccg
      481 tcctggatat tccctcaaac ccaacaggtc tctgtgccct gtctatcaac cattccaact
      541 cttacctggc ctatcctgga agccagagta caggcgagat tgtactctat gatggaaact
      601 ccctgaaaac ggtgtgcacc attgctgccc acgaggggac gctggccgct atcaccttca
      661 actcctcggg ctccaagcta gcaagcgcgt ctgaaaaagg cactgtcatc cgagtgttct
      721 ctgttcccga gggccagaaa ctctatgagt ttcgtcgagg aatgaaaagg tatgtgacaa
      781 tcagctccct ggtgttcagt atggactccc agttcctgtg tgcctccagc aacacggaga
      841 ccgtgcacat cttcaagatg gaacacctga cagacagccg cccagaagag ccttccacct
      901 ggagcggcta catgggaaag atgttcatgg cagctaccaa ctacctcccc gcccaggtgt
      961 cggacatgat gaaccaggac agggctttcg ccacaggacg cctgaacttc tctgggcaga
     1021 agaacatttg caccctgtcc acgatccaga aactgccgcg gttgctggtg gcctcctccg
     1081 acggacacct ttacatctac aacttggacc cacaggatgg aggagaatgt gtcctaatca
     1141 aaacccacag cttgcttagc tcaggaacaa cagaagagaa caaagaaaat gacctcagac
     1201 cttccttacc tccatcttat gctgcaactg tagcaaggcc cagcacgtct gcagcctcca
     1261 cggtgccagg atactctgag gacggcgggg cgctccgagg ggaagttatt ccggaacacg
     1321 agtttgcgac gggaccagtg tgtctagacg acgagaatga gtttccccct ataatcttgt
     1381 gccgtggaag tcagaagggc aaaacgaagc agtcctgaca agaagcctac ctcagaagtc
     1441 aggacactcc cctgtcaggt ggttttggag agaacgagga aagtggaaga aacggaatac
     1501 agtcaatgct gtgggcagag gggagggagg gaggcaggag tcctgggtgc ctcactgcag
     1561 tcaatgctgt gggcagaggg gagggaggga ggcaggagtc ccgggtgcct ccctgcttga
     1621 gccatagacc gcagttagcc ccccgaccca agcccctcag ccttgactgc cagtgggcaa
     1681 ggggaatgct ggagtcacac catgcagtct aaaagacctt caaaccacag tgtaaatgct
     1741 aactaaccat attggtatgt aaccagaatt ttatattaaa aagggcatcc ttgtcaaatg
     1801 tatgctgtgt aaaaaaa
//
