LOCUS       NM_001167860            4436 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WAS/WASL interacting protein family, member 3 (Wipf3),
            transcript variant 1, mRNA.
ACCESSION   NM_001167860 XM_001481284 XM_006506292 XM_620310
VERSION     NM_001167860.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4436)
  AUTHORS   O'Neil,S.D., Racz,B., Brown,W.E., Gao,Y., Soderblom,E.J., Yasuda,R.
            and Soderling,S.H.
  TITLE     Action potential-coupled Rho GTPase signaling drives presynaptic
            plasticity
  JOURNAL   Elife 10, e63756 (2021)
   PUBMED   34269176
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4436)
  AUTHORS   Suetsugu,S., Banzai,Y., Kato,M., Fukami,K., Kataoka,Y., Takai,Y.,
            Yoshida,N. and Takenawa,T.
  TITLE     Male-specific sterility caused by the loss of CR16
  JOURNAL   Genes Cells 12 (6), 721-733 (2007)
   PUBMED   17573773
  REMARK    GeneRIF: CR16 and N-WASP are suggested to play important roles in
            spermatogenesis
            Erratum:[Genes Cells. 2007 Aug;12(8):981. Banzai, Yoshibumi
            [corrected to Banzai, Yoshifumi]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087841.4.
            
            On or before Mar 5, 2019 this sequence version replaced
            XM_006506292.2, NM_001167860.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.26893.1,
                                           SRR7652917.1295373.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               AC087841.4         93423-93597
            176-355             AC087841.4         116563-116742
            356-488             AC087841.4         145522-145654
            489-623             AC087841.4         147562-147696
            624-1358            AC087841.4         148935-149669
            1359-1481           AC087841.4         151645-151767
            1482-1583           AC087841.4         152745-152846
            1584-1660           AC087841.4         160217-160293
            1661-4436           AC087841.4         164730-167505
FEATURES             Location/Qualifiers
     source          1..4436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 26.93 cM"
     gene            1..4436
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /note="WAS/WASL interacting protein family, member 3"
                     /db_xref="GeneID:330319"
                     /db_xref="MGI:MGI:3044681"
     exon            1..175
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            176..355
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..1684
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /note="isoform a is encoded by transcript variant 1;
                     corticosteroids and regional expression protein 16
                     homolog"
                     /codon_start=1
                     /product="WAS/WASL-interacting protein family member 3
                     isoform a"
                     /protein_id="NP_001161332.1"
                     /db_xref="CCDS:CCDS51779.1"
                     /db_xref="GeneID:330319"
                     /db_xref="MGI:MGI:3044681"
                     /translation="MPVPPPPPPPPPPPPPPPPPLGAPPPPPLGAPPPPPPPGPPVST
                     DTPSLRKPDLKGRSALLADIQQGTRLRKVTQINDRSAPQIEGSKGTSKEGGAAGSNAR
                     GGNTPPALGDLFAGGFPVLRPAGQRDVSGGKSGQGPGSRAPSPRLPIKAISGPLPAPA
                     SPRLGNASETHSSARPVPPRPSVPAPPPPTPPPPPPPPLPPASPIKAQLVSPPAPPTK
                     VNPSVVPPPLPCAPPLPPPPPTPPPLPPASALSDKAVRPQLAPLHLPPIPPPLPLLPP
                     CGYPGLHSEPNSPAQEVREPPAPPPPPPPPPPPPLPTYASCSSRTAVAPPPLPGANNS
                     GSETPPPLPPKSPSFQTQKALPTPPGAPGPQAILQKKRRGPGTSGGKLNPPPAPPARS
                     PTTELSSKSQQPGGQLRNGGQHAIDDFESKFTFHSMEDFPPPDEYKPCQKIYPSKVPR
                     SRTPGSWLQAEAAGQSSDDIKSRNSQLSLKALR"
     exon            356..488
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            489..623
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            624..1358
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1481
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1583
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..1660
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..4436
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1814..1819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /note="hexamer: AATAAT"
     polyA_site      1838
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
     regulatory      4415..4420
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /note="hexamer: AATAAA"
     polyA_site      4436
                     /gene="Wipf3"
                     /gene_synonym="9030621G03"
                     /note="major polyA site"
ORIGIN      
        1 gcagagtcca gcttagccgg gcgcgcagaa gcaacgccag gcactgtctg cagcccagcc
       61 gggatcctcg aggcgacggg gacgacggag acgacgggga cgacggagac gacggggaca
      121 gcggggacgg aggcgccagc taaagtccag tcggccgggt tacggccagc tgcagaccag
      181 aaactactct cttgggacca ttcataagtg agagacacca acactgtgac atatgccggt
      241 gccaccgcca ccaccgccac cacctccacc tccacctcca ccccctccac cactaggggc
      301 tccaccccct ccaccacttg gggcgccacc ccctccaccc ccaccagggc ctccggtcag
      361 cacagacacc cccagcttaa ggaagccaga tctgaaaggc cggagtgcac tgttggctga
      421 tatccagcaa ggaacacgcc tgcggaaagt cacccagatc aatgaccgca gtgccccaca
      481 gatcgagggt tcaaaaggaa ccagcaaaga gggaggagct gctggcagca atgccagggg
      541 aggaaacaca ccccctgccc tgggagatct ctttgctggt ggctttcctg tgttgagacc
      601 ggcaggccag agagatgtgt caggtggcaa gtccgggcag ggccctggct cccgagcacc
      661 ttctccccgg ctccctatca aagccatcag cggcccgctt cccgctcctg catctcccag
      721 gctaggcaat gcctcagaga cgcacagctc tgccaggcct gtccctcctc gccccagtgt
      781 gcctgcccca ccacctccca ctccaccccc acccccacct ccgcccctcc ccccagcctc
      841 ccccatcaaa gcccagttgg tgtccccgcc tgcccctcca accaaggtga atccatctgt
      901 ggtgccacct cctctaccct gcgcacctcc tcttccgccc cctcccccga ctccgccccc
      961 gctgccccca gcctcggcgc tgagcgacaa ggcagtgagg ccccaactag ccccactgca
     1021 cctgccaccc atcccacccc cgctccctct ccttccaccc tgtgggtacc ccgggctcca
     1081 ctcagagccc aacagccctg cacaggaggt gcgagaacct ccagctccgc caccgccacc
     1141 acccccacct ccgccaccac cgctccccac ctatgcctct tgctcctcga ggaccgctgt
     1201 ggccccgccc cctttgccag gcgcaaacaa cagcggcagc gagactcctc ccccgttgcc
     1261 ccccaagtcc cccagcttcc agacgcagaa ggccttgccc acacctccag gtgctcccgg
     1321 ccctcaggct atcctgcaga agaagcggcg aggcccagga accagtgggg gaaagctaaa
     1381 cccacctcca gccccacctg caagatcgcc caccacagag ctttccagca aaagccagca
     1441 gcctggaggc cagctgcgga atggaggcca gcacgcgatt gatgacttcg agtctaaatt
     1501 cacgttccac tccatggaag actttccccc tccagatgaa tacaaaccat gtcagaagat
     1561 ttaccccagc aaggtcccca gaagccgcac acctggttcc tggctccaag ctgaggcggc
     1621 tgggcagagc tctgatgaca tcaaaagcag aaactctcag ttatctctga aggcactccg
     1681 gtgagatgat ggtgaagcca aggccctggg gttctggatt ggatggacac caggacaact
     1741 cctcgagact ctactgtact caagctccac acatttgaca tacaggctca gaactgagca
     1801 tttgtttatt gtaaataatg atttgcacga accctaaagc accattttag tcagctttta
     1861 tttgagtaat attttaacat tttttaaaat atgcatcctg gcatttgtct gtctagtaca
     1921 ggtggtgccc tatcccaccc tgtggtgtcc actgtgtcta tagcacatgc ttgcaggctg
     1981 gtcctcctga aaccttttcc agagcatcct tagttttcaa gtagtccaaa agtcataact
     2041 ctccacaaca gcttcttatt ggcatgactc tcatcacacc aactgcaaaa tcaaaccaaa
     2101 taatgcctta taaaccatgc agctcagagg gagcagagtg tccccaggtc ctggtgtggc
     2161 cacacagctt ccagggagcg agatgccatg tctcgctccc tttttagcag tacagggatg
     2221 ccattttgct gcctaatgta tatatcccaa tgcaaaggct agagtgggtg tggcccctcc
     2281 catgccttcc gcagggcccc ttttgtaact caatcctttt acgagtagcc aatgctctta
     2341 ctgtttacag catccctagt gcccagtctc cacttccttc tgcccctcca tgttcccagc
     2401 gccatgctgg tagccagggt aaagtcagct ttatgagatt tttatatcct cccacccctg
     2461 cagaccacaa atgtatatag ctcatgattg tgataagttt attttttacc tcagtagtct
     2521 ccctctccaa actctactcg gagtgtaaga tttatgtgga aaatacaaca tatatttaaa
     2581 aaagaagaag atgaagaaga ggaagctgaa gaaagagacc cactggtaac atgcctgccc
     2641 gacaagccta agcaggaaaa gctgggtgcc gtacacattt ggtatcccat tgccggggag
     2701 gcagaggcag gcagatccct gcgactccct ggccagccaa gctaatcggg gaatcccagg
     2761 ttccagaaag tgacattgtc tcaaaacata cggtggcaac tcctgaggcc acaacaccca
     2821 aagttgacct cttacaggct cacacattac atgtgtgcac acatcccaca caggaacatg
     2881 tacagccatg tacaaacgca tacaaaagag caaagcagct cttcgagtat atctcaaata
     2941 tctggtcccg ttggtaggaa tgccatcagc ccaaaggtcc ttcccactga gctgaagaac
     3001 acagacaact ctcttgcctg gtggtgtgtg tctggggtgc tcctcagatg aatgcagcca
     3061 agtcagctgc cctgaataga cagagggcca ctccaggccg gggcagcaat ctgcaccctt
     3121 ctttgattct ccagggagtg aagtatgctt ttgcttcttg tcaggcccca aatgctccca
     3181 tccaccagag aggggaggct gtagcagagg aggggaaaga ggtaggaagc cgtctgagcc
     3241 ctcactgtgc tcagaatagc tgtagacaaa ggagaagggc actgagctat gatgagcttt
     3301 ggagcatctc actcaggcac tcaccccaca agaacattag cccagcccag gccatccagg
     3361 gtcaaaggat aaggagagtg tctgcagaca cctaactgtc atatggagca aatgtcctac
     3421 atgcttccag ataggtgaaa ctgagccagg gccaagtttc caacatctct ggggtaagga
     3481 ctcaagccac tgtaacagcc acatgaacag aggtgaaggt tccattcaac gctgactttg
     3541 ttgcgttggt tctggaagtg tgcagaaagg tcaggatcca gtctactctt ctcccagcca
     3601 cgcaaagtaa taatcattaa aaagctttca taactacgac aagggccatc tggaaggcag
     3661 ccctgccttt gaagtagtct gtttgcccag tacactgaag gacaccatgt tctacactgc
     3721 tggcacaaga atttaaacta ttcacgagtg gggagatgtc tctgtcagga gacgtcctgc
     3781 tgcccaagca tgagggcctg agctcatatc cccagcaccc acgtaaaagc caggcatagg
     3841 ggtgcatgtc tgtaatcctt ggtagaggag tgggtaaagt tgggtagagg cagctgatcc
     3901 tgggaaggtc agtgcccagc caacctcaca aaatgagcga tctgcaagct gcagggttag
     3961 tgagaaactg atagtagaga tagaccaaaa aagattcctg tgaatggcct ttgggcctcc
     4021 acatgcatgt gcacacatgt gcccttgttc atgcacacac acgcacacac cacacacaca
     4081 caaacacgac acataaatat tttttacaaa gttatttaag gtcagaagga aggaacatgc
     4141 agaaaccaaa aatagcaagc gaggaacggt ctcagggatc tggcctagca gctcaaggcc
     4201 tgtcatggag cctacccctc caagtccaag tgggtacctt cagtacccac cagcagcgca
     4261 tgggttaggc ccctggccat gaactcacat gtggagaggt cccctgctag ccttgcttac
     4321 cctcacattg cagactgtga ctcccccgat gtctcaccca atgttcttta tattttattg
     4381 aagttccctg ctgtggattt attcctttgt acctaataaa ctttaataag tgagaa
//
