LOCUS       NM_197940               7589 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WAS/WASL interacting protein family, member 2 (Wipf2),
            mRNA.
ACCESSION   NM_197940 XM_356561
VERSION     NM_197940.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7589)
  AUTHORS   Garber,J.J., Takeshima,F., Anton,I.M., Oyoshi,M.K., Lyubimova,A.,
            Kapoor,A., Shibata,T., Chen,F., Alt,F.W., Geha,R.S., Leong,J.M. and
            Snapper,S.B.
  TITLE     Enteropathogenic Escherichia coli and vaccinia virus do not require
            the family of WASP-interacting proteins for pathogen-induced actin
            assembly
  JOURNAL   Infect Immun 80 (12), 4071-4077 (2012)
   PUBMED   22966049
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591067.35.
            
            On Dec 17, 2009 this sequence version replaced NM_197940.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057854.1, SRR9219381.247549.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               AL591067.35        7022-7326
            306-436             AL591067.35        28398-28528
            437-569             AL591067.35        34124-34256
            570-686             AL591067.35        34920-35036
            687-1343            AL591067.35        35487-36143
            1344-1553           AL591067.35        39541-39750
            1554-1655           AL591067.35        42155-42256
            1656-7589           AL591067.35        43069-49002
FEATURES             Location/Qualifiers
     source          1..7589
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 62.71 cM"
     gene            1..7589
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="WAS/WASL interacting protein family, member 2"
                     /db_xref="GeneID:68524"
                     /db_xref="MGI:MGI:1924462"
     exon            1..305
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            306..436
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..1696
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="WASP-binding protein; WIP-related protein;
                     WASP-interacting protein-related protein"
                     /codon_start=1
                     /product="WAS/WASL-interacting protein family member 2"
                     /protein_id="NP_922922.1"
                     /db_xref="CCDS:CCDS25366.1"
                     /db_xref="GeneID:68524"
                     /db_xref="MGI:MGI:1924462"
                     /translation="MPIPPPPPPPPGPPPPPTFNQANTEQPKLSRDEQRNRGALLQDI
                     CKGTKLKKVTNVNDRSAPVIEKPRGSSGGYGPGAAALQPKGGLFQGGVPKLRPVGAKD
                     ASEAPAGKPALQVPSSRAAAPRPPGSAASGRPHDDTDSNRASLPELPRMQRPSLPDLS
                     RPNTASGTGMKHSSSAPPPPPPGRRANAPPTPLPLHSNKAQAYNREKPLPPTPGQRLH
                     PGREGHPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPEL
                     PQRHNSLHRKTPGPVRGLAPPPPTSATPSLLSNRPPPPAREPPSRGAAPPPPPPMIRN
                     GARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSF
                     LDDFESKYSFHPVEDFPAPEEYKHLQRVYPSKTNRAARGAPPLPPILR"
     exon            437..569
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            570..686
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            687..1343
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1553
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1655
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     exon            1656..7589
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5512..5517
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="hexamer: ATTAAA"
     polyA_site      5531
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="major polyA site"
     regulatory      5930..5935
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="hexamer: ATTAAA"
     polyA_site      5958
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
     regulatory      7030..7035
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
                     /note="hexamer: AATAAA"
     polyA_site      7051
                     /gene="Wipf2"
                     /gene_synonym="1110014J05Rik; 5730509C05Rik; Gm1176; Wich;
                     Wire"
ORIGIN      
        1 ggccctcggc tccctcctcc ttttcccccg cctccatttt gttcgcggac gctggggacg
       61 gtgggagcgg atccatttcc gggttggtaa aaggggcggc ggcgagagag agagagagag
      121 agagagagag agagagagag agagagagag agagagagag agagagagag cgagagagag
      181 cgagagagct tgccgcgggg cgaacgagca ggactaaacc aggactgagg tgacggagga
      241 ttcgctcccg gagcagcccc ccgccgagtg ggaaagacgc cggggcggct gagcccgccg
      301 ctgaggtata tgaatgacct aaagcggcaa ataaagacgg agagacaacg gtgccaactg
      361 gagcagggca agaatgccaa ttcctcctcc ccctccgccc ccgcctggtc ctcccccacc
      421 tcccacattt aatcaggcaa acacagaaca gcccaaactc agtagagatg agcagcggaa
      481 tcgaggcgcc ctcttacaag acatttgcaa agggaccaaa ctaaagaagg tgaccaacgt
      541 taatgatcgg agtgctcctg tcatcgagaa gcccagaggg agcagtggtg gctacggccc
      601 cggagctgct gctctgcagc ccaaaggagg tctctttcaa ggaggagtgc cgaagctccg
      661 acctgtggga gccaaggatg cttcagaggc tccagctggt aagccggccc tgcaagtccc
      721 cagctctcga gctgctgctc caaggcctcc ggggtctgca gccagtgggc gtcctcacga
      781 tgatacagac agcaaccgag cctccctccc agaactgccc cggatgcaga gaccctcctt
      841 accggacctc tctaggccca acaccgccag tggcacaggc atgaagcaca gctcctctgc
      901 acctccccca ccacctccag ggcggcgtgc caacgcgccc cccacccctc tgcctctgca
      961 cagcaacaaa gcccaagcct acaacaggga gaaaccattg cctccaacac ctggacagag
     1021 gctgcaccct ggacgagaag gacatcctgc tccaccccct gtaaagccac ctccttcccc
     1081 tgtgaacatc agaacaggac ccagtggcca gtctctggct cctcccccac cgccttaccg
     1141 ccagcctcct ggggtcccca atggaccctc aagccccacc aatgagtcag cccctgagct
     1201 gccacagaga cacaattctt tgcataggaa aacgccaggg cccgtcagag gccttgcacc
     1261 tcctccaccc acctcagcca ccccctcctt gttgagtaac aggccacctc ccccagcccg
     1321 agagcctcct agcaggggag cagctccccc gcccccaccg cccatgatcc gaaatggtgc
     1381 cagggatgct ccccctcctc ccccacctta ccggatgcat gggtcagagc caccaagcag
     1441 aggaaagccc ccacctccac cctccaggac accagctggg ccgccccctc ccccaccacc
     1501 ccccttgcgg aatggccata gagactccat caccactgtc cgctccttct tggatgactt
     1561 tgaatccaag tactccttcc atccagtgga ggacttccct gctccagaag aatataaaca
     1621 tcttcaaaga gtatacccca gcaaaacaaa ccgagctgcc cgtggagccc cacctctccc
     1681 acccattctc aggtgaagct tggcgtagtc ctgctcctca ggaaaaggat ggacctcctc
     1741 ttctcagatg gcctcccaac cctaatccct gcatgagagc tcctgcagtg tttctccagt
     1801 gcagccaacc caggctctga gcatcctcca gcccagctcc atctatgcat ctcctctctg
     1861 gactcggtga ttggactctt tctattggca gtagggtcta ctcccatctc caccttcttc
     1921 cagcaagccc tgctagccag aggaggagaa agcttccacg cctcctgctt tcttccaggg
     1981 aaaggtgcct tgttgtggtg aatggactca cattgggcag ggcagaaagt gtaacccctg
     2041 tctctgtcat tcaccgaggg cgaagtgtgg tgtgtgcatt atagcccata gtttaggagg
     2101 ttggtgtggc cagaacttct gaggagaggt gttccatgat gcagggaggg ggtttgcaga
     2161 gaagtgatct gttttaaagg tcgggttaca gaaaggacaa ggacatgggt cttcttcatt
     2221 ttcaagtgtt ttggttttgt tctcatcccc ttcccccatc ccaagagatg agcagtgcat
     2281 acacactaag tactgatccg ctaactaaac ggtaaagggc acgaagcaac ggagggtcat
     2341 ttcagagcca gtcagctctt gtgcagctaa gggccagggc tgtccgagct ctgggacctc
     2401 ctgccccttc cccagggtgc taggctgaac tgtgtccctt cccgatccca caagagaaga
     2461 gccactttgt tgagggcatt gtctattctc aagtcacaaa ccctacagac ttcctataag
     2521 acatggaaag atagggcctt agccacagcc tcctgatggc ttcagttttt tctgattaac
     2581 cctgaagtgg ccagcagcct gagtccttca gcccttgggg aaagctccag ggagacttaa
     2641 gaagggaacc gaagccctgg cttcatggga gtgtctggct cttcagggcc agtaaggtct
     2701 tggcagcctg ctcatagcga gactctcaca cccatcagac ggcaggctct tcctgttttc
     2761 tctgccaccc acccatacct tactgagact gcagggttta aggccacagc gtagaaaagg
     2821 gagcttcagg aggaatacag agtcctgtaa gccaagcaca aagacatagg gaggcatgcc
     2881 gcccgccatc taggaggtgg gtcttccctg gcggccagca atacatcgtt tctcagtctt
     2941 ccaaggtgta gggaaacagc acaggaagtg ggtgttccaa cggaggccgc tctgttggcc
     3001 aggaagtgtc tcttctccac tagcagtgtg gggcgcctga actccacacc cagagaagtt
     3061 ggtttctgac agtccttgac ctgggcacaa gctgctcaga tcttacatca cggtagggag
     3121 accaggctgt tctctgagtt gggtagggga agctagtgaa aaacttccag atacaccatg
     3181 gggttaaatt atcgtagggg ctgtcctttt tttttttatt attattatta tttttatttt
     3241 tattctccgc ccaccccact ccactcccac cccctaagac agggtttctc tgtgcattcc
     3301 tggctgtcct ggaacttatt ttctagacca ggctggcctc aaactcagag atcccctgtc
     3361 tctgcctccc aggtgctggg actaaaggtg tgcgccacca cgcttggctc atagggacct
     3421 ttctaatcta gtggaccata ggctaaggat ctgtgtgtaa tgccaggtca gacccaaatc
     3481 ttctaggact ggagaaagtg gacctaactt agttcattta tttattgagt gttgcccatt
     3541 gccagctctt ggaccacttg gacttttggg acaggcagtg gttagatctt accggacttt
     3601 taattgttca ctatttatct tcttctcaaa tctgttagca gttacgctcc cagcatccta
     3661 acttgaacaa agggaagaga gggaaaaaaa gctgacactt ggagagttcc agggtagatt
     3721 ctaatggttg aactgtgaag tcttcccatt tgttgttgaa atgggagctg atgccttttg
     3781 tacaatgtta tcaaagtgtg aaaattttcc cttactgaag catagaccat cagatatatg
     3841 cgtgcgtatt tatgtatgtg tatatatata tatatgtata tacacacaca catatagatt
     3901 tgtatacaca cacatacatc tactcacaaa gccaaacccg ggctttttgc ttgggctgat
     3961 ggtaccttcc tcgacttgac ctgccaccct ttctaatccc cagaatcaga ctgtgccgcg
     4021 tgggtattga tgatatattt tcgttgtctt tgcctggtgg aaccaccacc aaaaaaaggc
     4081 ttgaatttag atctacatga gtgagtttgc tcctccagtt aacggattgt gttgatgaca
     4141 caacccctaa cttaaatgtc tttgccttat tcatcatttg gtcctgctgt taataacaaa
     4201 tttattatca tgtatatttg ctattgaaga tgggagtgtg atcctcaaaa ttgttggtct
     4261 gttttatata ttgtacacag cttgtaatgc aggtttaagg tagccgggct gtgaaaaccc
     4321 tgacactgtt cccctttaaa ctgtccttga tgtcctcatg ggaatgtcgt ctcttcagtg
     4381 gaagattggg tggtctcatg ttgaggctat tacttagtcc ctttaatccc cttgtcccct
     4441 cccaaagggg agagacattg cccagctaag cagccagaag ctctgtcaca gctttcgtgg
     4501 tatttttccc tagtgggaaa cgctggatgg ctgtttctta ctgccctgcc ctgtcaggcg
     4561 gtggttctga ttttcaaatg agctagatgc tcctctttcc ctttctccag tcaccaaacc
     4621 tggaccaaag tacttcatat tccaggtgtg ggttcctctc tcctgggatt tgctgcagct
     4681 gcagagccct gcccttttcg cagccttggc cacttgtgtg agccactagg gccatcccag
     4741 cctgatggac gggaggcggt cctcaccagg aattcaattc attccctgcc ccctttccta
     4801 gcctaggcag agaaactagt cactggccat tgccctgggg gaatcccctc acgcagtggc
     4861 ttcccatctt agaacccgga cttacctcca ggcggaggtg aggggtgggg agtactgtaa
     4921 atagacttgc tgcagagcaa ctcagggttg gggtatgttt gagttctcct gatcacttga
     4981 aaactaatct gtaggctgaa tgcttctgga gtgtggggga aatgtgactc cggggtcctt
     5041 tgtcctctga ggctctgcgg gtggagggta ggacttcaga ggccctttga tagcacggct
     5101 gcgctgtctg cccttctgga aacccaacct gccatcagct gtaaatcaga ttcttcacat
     5161 tccaggtgta agctttccct tccctgtgac tctcagtccc tagctacatg gtcaggggga
     5221 ctctgttaaa ccacccaaat ttagggaatg agaggggaga gaggaggcca ttaggagtct
     5281 gccttcaaga ctcatttctt gaaaacaaaa tggaaaaaaa aaaagataac caccttcaat
     5341 cacaggcaaa aactaaacca agaaaaaaaa aaaaaaagca aacaaaccaa aaaacccaac
     5401 agcaaccatg taactgaagg aagggtctgg ttccgctcca tcccgtgttc attgtgcctt
     5461 tacttgtgtt agatctctgt gctttcttcc tccccctcta tgacgtcatt aattaaagcc
     5521 ttccttgata accgctgttt cctttctgct cctgtttctt acagcttggt gggtttcttc
     5581 tctgattgtc ttccatctta ctcgcctggt ggcagagggg cttagcgcac acacgcaccc
     5641 tctttttttt tttctaactt ctcctttccc acagtttcca gcctggaagt tacagtcaac
     5701 actgagtaag agaccagagt gattgtgtgc atgtgcgcgt gtgtgtgtcc atctgcatgt
     5761 gcgtcagttt ctttgaaaaa taatttattg tgtgatttcc tgtggagttt ttgttcaggt
     5821 tacagtgctg ctccacaata gcacggatcc ctgtccccct acccccggca taaaatgtat
     5881 tatctggtct caggttggat tccttggtac gtttctttct gtgcagttta ttaaacctta
     5941 aaaggaaaaa aacaaaaagg aaaacctctg tgtattcttg tcgtgagcaa tactgtttca
     6001 agtgactgca gggagagagg aggaaacccc atggtctcct cttctggaca aacgtggcag
     6061 tttgagttca ggctccctta agagaggacc tgtgggtggg tgtggcagaa acacttgcag
     6121 ctttctgggg cctttctgcc tgtgcgtttt atttttgttt ttgttttttg tttgtttgtt
     6181 tggttggttg gtttttcaag acagggtttc tctgtgtagc tctggctatc ctggaactca
     6241 ctctgtagac caggctggcc tcgaactcag aaatccgcct gcctctgcct cccaagtgct
     6301 gggattaaag gcgtgcacca ccactgcccg gctgcctgtg cgttttttag aagtcaccct
     6361 tttggcctgg ccaaccagtg attctgtttt gtattttctg cttcattccc cttgcctttc
     6421 tctcaaggag ccccagaggc tcctttccgt ggggtctgtt ccttgtgacc ccttagactc
     6481 tgtcttcctg tgcccgtgct tccaggccga ttcgcgccag acagtggaag aaaaggtggg
     6541 ggcagggccc acatcttgtg aagctctgca tagtcctgct gatcctggaa ctcactgtgt
     6601 agaccaggat agccttgaac tagatcctct tgcttcttcc tgtgcaaggt ttggaccacc
     6661 acaactgcct tttcagccga gatcttagcc ggttttcttg agctttgact ttaggtgtta
     6721 aaattctacc aggcctcttt gtttctgtgt ttgccactga tagtaactgc agctgagtcc
     6781 actgaatttg actgcacttt cactgatagc agaccagcca gttacttccc tctgggttta
     6841 taatgggtgt gtgtgtgtag atagctctca aggaatctag gtagatataa tgggggtgtg
     6901 tgtctgtctg tctgtctgtc tgtctcttgc tctcagggaa tctagattag gaaaacttgc
     6961 tggggaaagg ttactaccag agtggctgaa ttcctgatta tttgatccat tattgttatt
     7021 aatatgaata ataaactatt tattgatttc attattcttt ctgacttaat agcctgcatt
     7081 atggcatttg cttaaatgac ccccaacttc cagccctgta aatgacctca ctccgatagt
     7141 atcgttggtc cttgtgtgta cctttgcaca tgctcaaaga aagatgccag acaggtcttt
     7201 ccagtgtgac ttgattcctg ctctgtgacc ccgcttgagt taagtgataa gaacaccagc
     7261 ttgctcactg ctgattgctc aggcacagct gtgtgtgctg tgaatgtgtc tcgagtattt
     7321 cctggcccag accatgaact gcaactcgtg ggacggaagc taccttcctc ttgcttgtga
     7381 attctccgca gatggtaaaa tgccaatctc aggatcatga ccacaccaga gaagaactac
     7441 aagaaggctt tttcaccttt gacaccacgg acgcccagtc tgatctgttt ttgcacataa
     7501 ttaaatgtat tcttctacgt ttatggcttt gagatttaaa agactgtgta tgtgctttcc
     7561 aaccataaaa atcattcctg cacacagtg
//
