LOCUS       NM_001012725             809 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus WAP four-disulfide core domain 6B (Wfdc6b), mRNA.
ACCESSION   NM_001012725 XM_485099
VERSION     NM_001012725.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Andrade,A.D., Almeida,P.G.C., Mariani,N.A.P., Freitas,G.A.,
            Kushima,H., Filadelpho,A.L., Spadella,M.A., Avellar,M.C.W. and
            Silva,E.J.R.
  TITLE     Lipopolysaccharide-induced epididymitis modifies the
            transcriptional profile of Wfdc genes in micedagger
  JOURNAL   Biol Reprod 104 (1), 144-158 (2021)
   PUBMED   33034631
REFERENCE   2  (bases 1 to 809)
  AUTHORS   Clauss,A., Lilja,H. and Lundwall,A.
  TITLE     The evolution of a genetic locus encoding small serine proteinase
            inhibitors
  JOURNAL   Biochem Biophys Res Commun 333 (2), 383-389 (2005)
   PUBMED   15950183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591478.19.
            
            On Oct 24, 2022 this sequence version replaced NM_001012725.2.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus. The use of an alternative upstream start codon, which
            appears to be rodent-specific, would result in a protein that is 10
            aa longer at the N-terminal.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY541526.1, BC141216.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-176               AL591478.19        166769-166944
            177-311             AL591478.19        167962-168096
            312-482             AL591478.19        170347-170517
            483-809             AL591478.19        170958-171284
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 85.22 cM"
     gene            1..809
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /note="WAP four-disulfide core domain 6B"
                     /db_xref="GeneID:433502"
                     /db_xref="MGI:MGI:3575430"
     exon            1..176
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..502
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /note="WAP four-disulfide core 6-like 1; putative protease
                     inhibitor WAP6B; WAP four-disulfide core domain protein
                     6B"
                     /codon_start=1
                     /product="WAP four-disulfide core domain protein 6B
                     precursor"
                     /protein_id="NP_001012743.2"
                     /db_xref="CCDS:CCDS17046.2"
                     /db_xref="GeneID:433502"
                     /db_xref="MGI:MGI:3575430"
                     /translation="MPPNRLLLPKMRLWGLLPFLVPFILLWSIQEPALAEGVFIRTCP
                     KYNKIKCDFEERNQCLRHRECPGEERCCLFACGRKCLDLSEDICSLPQDAGPCLAYLP
                     RWWYNQDTKLCIEFIYGGCQGNPNNFESKAVCTSICINKRKMSSWI"
     exon            177..311
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /inference="alignment:Splign:2.1.0"
     exon            312..482
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /inference="alignment:Splign:2.1.0"
     exon            483..809
                     /gene="Wfdc6b"
                     /gene_synonym="WAP6b; Wfdc6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgggctgt tggggcagca gaggccggag ccactgacaa actcctcctg gtttaatgcc
       61 tccaaacagg ctactgcttc ctaaaatgag actctgggga cttctgccat tcctggtccc
      121 cttcatcctc ctgtggagca tccaggaacc tgcgctggca gagggggtct ttataagaac
      181 atgtccaaag tataataaaa taaagtgtga ctttgaagaa agaaaccagt gtttacgaca
      241 cagagagtgt ccaggggagg aaaggtgctg cctgttcgcc tgtgggagga aatgcctgga
      301 cctcagcgaa gatatatgca gtctgcccca ggatgctggt ccctgcttgg cctaccttcc
      361 acgctggtgg tataaccaag acaccaagct ttgtatcgaa ttcatctatg gtggttgcca
      421 agggaaccct aacaacttcg aatctaaagc tgtctgtaca tccatttgca taaacaaacg
      481 caaaatgtct tcctggatat gataaggagg agctggagga agctccaggt cttggctcct
      541 aatctgaggc cttcttcccg ggaaccgacg cctgctccgg attggccgcc agtggccaag
      601 tcttagccac tgagacttta gctgttccca aaccagaacc ctagactttg cttattccct
      661 tcccccaacc ccagcttctc ttcaagtgtc atgaccttcg acctttgacc ccctcctcag
      721 cctgggactc tcatcacctc aactttcagg gctccgattt gttcctatga aatctggttc
      781 ctcctaataa aggattctgt gagttctga
//
