LOCUS       NM_001177848             805 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WAP four-disulfide core domain 6A (Wfdc6a), transcript
            variant 1, mRNA.
ACCESSION   NM_001177848
VERSION     NM_001177848.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Andrade,A.D., Almeida,P.G.C., Mariani,N.A.P., Freitas,G.A.,
            Kushima,H., Filadelpho,A.L., Spadella,M.A., Avellar,M.C.W. and
            Silva,E.J.R.
  TITLE     Lipopolysaccharide-induced epididymitis modifies the
            transcriptional profile of Wfdc genes in micedagger
  JOURNAL   Biol Reprod 104 (1), 144-158 (2021)
   PUBMED   33034631
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK136589.1, BC147597.1 and AL591478.19.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136589.1, BB583816.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-562               AK136589.1         2-563
            563-667             BC147597.1         537-641
            668-805             AL591478.19        132590-132727       c
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 85.21 cM"
     gene            1..805
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /note="WAP four-disulfide core domain 6A"
                     /db_xref="GeneID:209351"
                     /db_xref="MGI:MGI:2684968"
     exon            1..178
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..498
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; likely orthologue of H. sapiens WAP
                     four-disulfide core domain 6 (WFDC6); putative protease
                     inhibitor WAP6A; WAP four-disulfide core domain protein
                     6A"
                     /codon_start=1
                     /product="WAP four-disulfide core domain protein 6A
                     isoform 1 precursor"
                     /protein_id="NP_001171319.1"
                     /db_xref="GeneID:209351"
                     /db_xref="MGI:MGI:2684968"
                     /translation="MPPNRLLLPKMRLWGLLPFLVPFILLWSIQEPELAEGFFIRTCP
                     RVRVKCEVEERNECTRHRQCPNKKRCCLFSCGKKCMDLRQDVCSLPQDPGPCLAYLPR
                     WWYNQETDLCTEFIYGGCQGNPNNFPSEGICTVVCKKKQMSSWI"
     exon            179..310
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /inference="alignment:Splign:2.1.0"
     exon            311..478
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /inference="alignment:Splign:2.1.0"
     exon            479..805
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /inference="alignment:Splign:2.1.0"
     regulatory      782..787
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /note="hexamer: AATAAA"
     polyA_site      805
                     /gene="Wfdc6a"
                     /gene_synonym="Gm122"
                     /note="major polyA site"
ORIGIN      
        1 ttcctgggct gttggggcag cagaggccgg agccactgac aaactcctcc tggtttaatg
       61 cctccaaaca ggctactgct tcctaaaatg agactctggg gacttctgcc attcctggtc
      121 cccttcatcc tcctgtggag catccaggaa cctgagctgg cagagggttt ctttatcaga
      181 acatgcccaa gagtcagagt gaagtgtgag gttgaagaaa gaaatgagtg tacaaggcac
      241 cgacagtgtc caaacaagaa gaggtgttgc ctgttcagct gtgggaagaa atgcatggac
      301 ctcaggcaag atgtatgcag tctgccccag gaccctggtc cctgcttggc ctaccttcca
      361 cgctggtggt ataaccaaga aactgacctc tgtaccgaat tcatctatgg tggttgtcaa
      421 gggaacccta acaacttccc atctgaaggt atctgcaccg ttgtctgcaa aaagaaacaa
      481 atgtcttcct ggatatgata aggaggagct ggaggaagct ccaggtcttg gctcctaatc
      541 tgaggccttc ttcccgggaa ccgacgcctg ctccggattg gccgccagtg gccaagtctt
      601 agccactgag actttagctg ttcccaaacc agaaccctag actttgctta ttcccttccc
      661 ccaaccccag cttctcttca agtgtcatga ccttcgacct ttgaccccct cctcagcctg
      721 ggactctcat cacctcaact ttcagggctc cgatttgttc ctatgaaatc tggttcctcc
      781 taataaagga ttctgtgagt tctga
//
