LOCUS       NM_183271                496 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus WAP four-disulfide core domain 15A (Wfdc15a), mRNA.
ACCESSION   NM_183271
VERSION     NM_183271.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Tomizawa,S.I., Fellows,R., Ono,M., Kuroha,K., Dockal,I.,
            Kobayashi,Y., Minamizawa,K., Natsume,K., Nakajima,K., Hoshi,I.,
            Matsuda,S., Seki,M., Suzuki,Y., Aoto,K., Saitsu,H. and Ohbo,K.
  TITLE     The non-canonical bivalent gene Wfdc15a controls spermatogenic
            protease and immune homeostasis
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39222051
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Andrade,A.D., Almeida,P.G.C., Mariani,N.A.P., Freitas,G.A.,
            Kushima,H., Filadelpho,A.L., Spadella,M.A., Avellar,M.C.W. and
            Silva,E.J.R.
  TITLE     Lipopolysaccharide-induced epididymitis modifies the
            transcriptional profile of Wfdc genes in micedagger
  JOURNAL   Biol Reprod 104 (1), 144-158 (2021)
   PUBMED   33034631
REFERENCE   3  (bases 1 to 496)
  AUTHORS   Clauss,A., Lilja,H. and Lundwall,A.
  TITLE     The evolution of a genetic locus encoding small serine proteinase
            inhibitors
  JOURNAL   Biochem Biophys Res Commun 333 (2), 383-389 (2005)
   PUBMED   15950183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591512.11.
            
            On Oct 24, 2022 this sequence version replaced NM_183271.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY706929.1, BY706758.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-187               AL591512.11        130477-130663       c
            188-346             AL591512.11        130183-130341       c
            347-496             AL591512.11        129388-129537       c
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 84.64 cM"
     gene            1..496
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /note="WAP four-disulfide core domain 15A"
                     /db_xref="GeneID:68221"
                     /db_xref="MGI:MGI:1915471"
     exon            1..187
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..345
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /note="WAP four-disulfide core domain protein 15A"
                     /codon_start=1
                     /product="WAP four-disulfide core domain protein 15A
                     precursor"
                     /protein_id="NP_899094.1"
                     /db_xref="CCDS:CCDS38319.1"
                     /db_xref="GeneID:68221"
                     /db_xref="MGI:MGI:1915471"
                     /translation="MKPSSLLLFTTTILLCLSMAQPRATRKGVTPKQGYCPEFLLDCP
                     FVLLPVCSRDKGCKGTKKCCFYYCQMRCVEPWTTLT"
     exon            188..346
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /inference="alignment:Splign:2.1.0"
     exon            347..496
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      474..479
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /note="hexamer: ATTAAA"
     polyA_site      496
                     /gene="Wfdc15a"
                     /gene_synonym="1700049M11Rik; Wfdcl1"
                     /note="major polyA site"
ORIGIN      
        1 acctgtgacc tcagcttccc tgctggttat ccacggccca gcgcagcggc agattcaaac
       61 gtcctccctc catgttcaca gggcagtcaa tcctctcggg agatgaagcc aagcagcctc
      121 ctactgttca caacaaccat cctcctttgc ctcagcatgg cgcagcctag agcaactagg
      181 aaaggagtta cgccgaaaca ggggtactgt ccggagtttc ttcttgactg cccgtttgtc
      241 ctgttacccg tatgcagccg tgataaaggg tgcaagggca ccaaaaaatg ctgcttctac
      301 tactgtcaga tgcggtgtgt ggaaccctgg acaaccttga cttgaaatga aaaacctttc
      361 ttaaccaagt cttggaaaat aacgacggca ttggctccaa cttggatggc tgacctcgag
      421 ttcttctgtc tcatagaccc ctcttattag tgaattaaat gtgtattatt aatattaaag
      481 caaaactaaa aataca
//
