LOCUS       NM_028026               2132 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus WD repeat domain 73 (Wdr73), transcript variant 1,
            mRNA.
ACCESSION   NM_028026 XM_001479473 XM_001479496
VERSION     NM_028026.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2132)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2132)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   3  (bases 1 to 2132)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 2132)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK169527.1, AK010448.1, AK169377.1 and BM940898.1.
            
            On Jul 30, 2009 this sequence version replaced NM_028026.1.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK169527.1, AK049132.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-315               AK169527.1         1-315
            316-1415            AK010448.1         282-1381
            1416-2113           AK169377.1         1853-2550
            2114-2132           BM940898.1         486-504
FEATURES             Location/Qualifiers
     source          1..2132
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.71 cM"
     gene            1..2132
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /note="WD repeat domain 73"
                     /db_xref="GeneID:71968"
                     /db_xref="MGI:MGI:1919218"
     exon            1..85
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1160
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /codon_start=1
                     /product="WD repeat-containing protein 73"
                     /protein_id="NP_082302.2"
                     /db_xref="CCDS:CCDS52282.1"
                     /db_xref="GeneID:71968"
                     /db_xref="MGI:MGI:1919218"
                     /translation="MELAEDWLVESLRLYQDFHAFDLSGATRVLEWIGEKGVFVAGYE
                     SLKKNEILHLILPLRLSVQENQGLHPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTSG
                     LPGCYIQMWQVREDNDVIEAVSTIDVQDKEESLWPRVSVFCSKAPGILHGARLSGLRT
                     VDVESQKITYSSGTADSESLSCLQVLDANTFAFCGNSGRLGLVDTRQKWAALETVSPG
                     SGCSGERWCAEVRNKGQGPGPCIASLGSDGQLCLLDSRNLCHPVSSAQCPVFKPSPDP
                     ELLRVTWAPGLDNCLAISGFDGTVQIYDVTSWDGKKTQAEPLFTHKGHIFLDGNDVDS
                     APLVTTHTWHPRKPRTLLSAASDSSLHVWDWVDLQAS"
     exon            86..153
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            154..242
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            243..331
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            332..396
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            397..561
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            562..927
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            928..2114
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1552..1557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /note="hexamer: AATAAA"
     regulatory      1568..1573
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /note="hexamer: AATACA"
     polyA_site      1578
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /note="major polyA site"
     polyA_site      1585
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
     regulatory      2094..2099
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2114
                     /gene="Wdr73"
                     /gene_synonym="1200011I23Rik; 2410008B13Rik"
ORIGIN      
        1 gaagtctggc tggcggaagt ggagcgacgg aagccacagt tgctatggag ctcgctgagg
       61 actggctcgt ggagtctttg cgattgtacc aagacttcca tgcatttgac ctctcaggag
      121 ccactcgagt ccttgagtgg attggtgaaa aaggagtctt tgttgctggt tatgaaagtt
      181 tgaaaaaaaa tgagattctt catttgatac tacctctcag gctctctgta caggaaaacc
      241 agggtttaca cccagagagg gacttcaaag tacgccatgg aggattttca gacagatctg
      301 tctttgacct aaagcatgtg ccagatacca ggttgctggt gaccagtgga cttccagggt
      361 gttacataca aatgtggcaa gtcagagagg acaacgatgt cattgaagca gtcagtacca
      421 tcgatgtgca ggacaaagag gagagtctct ggcctcgggt gtctgtcttc tgctctaagg
      481 caccaggaat cctccacggg gcgcggctca gcggcctgag gactgtggat gtagaatccc
      541 agaagatcac atatagctca ggtacagctg acagtgagtc cttgagctgc cttcaggtcc
      601 tagacgcaaa tacctttgct ttctgtggca actcaggtcg gctggggctt gtggacaccc
      661 gccagaagtg ggcagcgttg gagactgtca gccccggctc tggctgtagt ggagagagat
      721 ggtgtgcaga agtcaggaac aagggccaag gccctgggcc ctgcattgcc agccttggct
      781 cagatgggca gctctgtctc cttgactccc ggaatctctg tcatcctgtg agctcagccc
      841 agtgtccggt gttcaaaccc agccctgacc cagagctgct gcgggtgact tgggctccgg
      901 gcctggacaa ctgcttggct atttcaggct ttgatgggac agtacaaatc tatgatgtca
      961 catcatggga tggaaagaaa acccaagcgg agcctctctt cactcacaaa ggccacatct
     1021 tcctggatgg aaatgacgta gactctgctc ctctggtcac cacccatacc tggcaccctc
     1081 gcaaacccag aactttgtta tcagcagcaa gtgattcttc tctgcatgtg tgggactggg
     1141 tggacctcca ggcctcctga tgacacagca gctgccctca tgggcctctg agaagaggag
     1201 ttgtttgaga ggctgacatg gactgtgagt gaacacagct ctaccacagc cgttggcttc
     1261 aggcaagcta gcctgccctt cttgtccctt tttcttacct gtaaaatgaa ggtgtagtag
     1321 gtaccaccta gtgctgtggg gagcatcaca agaaaattac ctgagaacag ttggtagggc
     1381 gcacggcata acatggctgg aagcgaccat tgcctctagg agccctgcgt ctccaggtgt
     1441 atagcagcag gctgtgttcc tgtcttcaca gcatcatggt gagaatcagg agagctggag
     1501 tgtgaatgtg ggtgtgaact ttctcacaga aggaatcgat gtctcagggc caataaacat
     1561 caaaaagaat acaagtaaga agcaattagc aatttactta gtttttgtac acaagactgg
     1621 actggactga gcctactgtt ctgagttatg ccccaactgc tttcttttac ttcttcctat
     1681 tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgttcgtgtt
     1741 cattacttgc acgagggtgc acgtgcttgg gtgtgcacac tcatgagtat aggcaccaag
     1801 aagtgctggg aaggtggagt catcccgagg cctctgcttt gctaaaggat gcaccttgct
     1861 ttcctcgtgc acacgtgacc tctgcatgct gactggagta agctctgtct tccactctgg
     1921 tggataaggg tcccttcctt atgaccttgt ttagccttag ttcctagacc cctctccaaa
     1981 tctagtctct cggggtaggg acttcagtgt atgaatttgc aaggggtaca cacttctgtc
     2041 cacagcactt aaaaataatg gggggataag aaaagtctaa cagctttttt tataataaat
     2101 ttttttaaga tgtaaaaaaa aaaaaaaaaa aa
//
