LOCUS       NM_001014981            7109 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus WD repeat domain 7 (Wdr7), transcript variant 1, mRNA.
ACCESSION   NM_001014981 XM_140391 XM_915908
VERSION     NM_001014981.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7109)
  AUTHORS   Di Michele,M., Attina,A., Roux,P.F., Tabet,I., Laguesse,S.,
            Florido,J., Houdeville,M., Choquet,A., Encislai,B., Arena,G., De
            Blasio,C., Wendling,O., Frenois,F.X., Papon,L., Stuani,L.,
            Fuentes,M., Jahannault Talignani,C., Rousseau,M., Guegan,J.,
            Buscail,Y., Dupre,P., Michaud,H.A., Rodier,G., Bellvert,F.,
            Kulyk,H., Ferraro Peyret,C., Mathieu,H., Close,P., Rapino,F.,
            Chaveroux,C., Pirot,N., Rubio,L., Torro,A., Sorg,T., Ango,F.,
            Hirtz,C., Compan,V., Lebigot,E., Legati,A., Ghezzi,D., Nguyen,L.,
            David,A., Sardet,C., Lacroix,M. and Le Cam,L.
  TITLE     E4F1 coordinates pyruvate metabolism and the activity of the
            elongator complex to ensure translation fidelity during brain
            development
  JOURNAL   Nat Commun 16 (1), 67 (2025)
   PUBMED   39747033
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7109)
  AUTHORS   Zagore,L.L., Grabinski,S.E., Sweet,T.J., Hannigan,M.M.,
            Sramkoski,R.M., Li,Q. and Licatalosi,D.D.
  TITLE     RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell
            Development
  JOURNAL   Mol Cell Biol 35 (23), 4030-4042 (2015)
   PUBMED   26391954
REFERENCE   3  (bases 1 to 7109)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   4  (bases 1 to 7109)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   5  (bases 1 to 7109)
  AUTHORS   Ding,S., Wu,X., Li,G., Han,M., Zhuang,Y. and Xu,T.
  TITLE     Efficient transposition of the piggyBac (PB) transposon in
            mammalian cells and mice
  JOURNAL   Cell 122 (3), 473-483 (2005)
   PUBMED   16096065
REFERENCE   6  (bases 1 to 7109)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7109)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 7109)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 7109)
  AUTHORS   Sanders,S., Keck-Waggoner,C.L., Zimonjic,D.B., Popescu,N.C. and
            Thorgeirsson,S.S.
  TITLE     Assignment of WDR7 (alias TRAG, TGF-beta resistance associated
            gene) to orthologous regions of human chromosome 18q21.1-->q22 and
            mouse chromosome 18D.1-E.3 by fluorescence in situ hybridization
  JOURNAL   Cytogenet Cell Genet 88 (3-4), 324-325 (2000)
   PUBMED   10828621
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102040.16, AC102132.3 and AC157903.3.
            
            On or before Apr 11, 2009 this sequence version replaced
            XM_915908.2, XM_140391.5.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC137785.1, SRR10223969.18650.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-225               AC102040.16        203088-203312
            226-397             AC102040.16        214611-214782
            398-504             AC102040.16        215150-215256
            505-583             AC102040.16        218514-218592
            584-758             AC102040.16        222012-222186
            759-835             AC102040.16        222832-222908
            836-955             AC102040.16        224483-224602
            956-1101            AC102040.16        229972-230117
            1102-1204           AC102040.16        230797-230899
            1205-1346           AC102040.16        233136-233277
            1347-1595           AC102040.16        233498-233746
            1596-1816           AC102040.16        234420-234640
            1817-2012           AC102040.16        249429-249624
            2013-2227           AC102132.3         33920-34134
            2228-2997           AC102132.3         50877-51646
            2998-3086           AC102132.3         53218-53306
            3087-3182           AC102132.3         65145-65240
            3183-3301           AC102132.3         67574-67692
            3302-3425           AC102132.3         69507-69630
            3426-3539           AC102132.3         98474-98587
            3540-3761           AC102132.3         138634-138855
            3762-3948           AC102132.3         177379-177565
            3949-4066           AC157903.3         179512-179629       c
            4067-4216           AC157903.3         177713-177862       c
            4217-4299           AC157903.3         177093-177175       c
            4300-4399           AC157903.3         168493-168592       c
            4400-4504           AC157903.3         125017-125121       c
            4505-7109           AC157903.3         114681-117285       c
FEATURES             Location/Qualifiers
     source          1..7109
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 37.09 cM"
     gene            1..7109
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /note="WD repeat domain 7"
                     /db_xref="GeneID:104082"
                     /db_xref="MGI:MGI:1860197"
     exon            1..225
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            226..397
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..4708
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /note="isoform 1 is encoded by transcript variant 1; WD
                     repeat-containing protein 7; TGF-beta
                     resistance-associated protein TRAG; TGF-beta resistance
                     associated"
                     /codon_start=1
                     /product="WD repeat-containing protein 7 isoform 1"
                     /protein_id="NP_001014981.1"
                     /db_xref="CCDS:CCDS50307.1"
                     /db_xref="GeneID:104082"
                     /db_xref="MGI:MGI:1860197"
                     /translation="MAGNSLVLPIVLWGRKAPTHCISSILLTDDGGTIVTGCHDGQIC
                     LWDVSVELEVNPRALLFGHTASITCLSKACASGDKRYTVSASANGEMCLWDVNDGRCI
                     EFTKLACTHTGIQFYQFSVGNQQEGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDW
                     ISSMSIIRSQRTQEDTVVALSVTGILKVWIVTSEMSGMQDTEPIFEEESKPIYCQNCQ
                     SISFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGGDFVSADKVIIWTE
                     NGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHSLLDQKDKELVICPPVTRFFY
                     GCKEYLHKLLIQGDSSGRLNIWNIADIAEKQEADEGLKMTTCISLQEAFDKLKPCPAG
                     IIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIIIVPATQTAIVQLLQGEHML
                     RRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIF
                     CVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVI
                     KWRPSDDYLVVGCTDGSVYVWQMDTGALDRCAMGITAVEILNACDEAVPAAVDSLSHP
                     AVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTN
                     LTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAA
                     VLFQQVKETIKENIKEHLLDEEEDEEEARRQSREDSDPEYRASKSKPLTLLEYNLTMD
                     TAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYNQAAG
                     KLLHAKAEVGRKLPAAEGVGKGTYTVSRAVTTQHLLSIISLANTLMSMTNATFIGDHM
                     KKGPTRPPRPGTPDLSKARDSPPPSSNIVQGQIKQAAAPVVSARSDADHSGSDSASPA
                     LPTCFLVNEGWSQLAAMHCVMLPDLLGLERFRPPLLEMLARRWQDRCLEVREAAQALL
                     LAELRRIEQAGRKETIDTWAPYLPQYMDHVISPGVTAEAMQTMAAAPDASGPEAKVQE
                     EEHDLVDDDITAGCLSSVPQMKKISTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLL
                     TRPRSSSQIPEGFGLTSGGSNYSLARHTCKALTYLLLQPPSPKLPPHSTIRRTATDLI
                     GRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIA
                     TARPPAFITTIAKEVHRHTALAANTQSQQSIHTTTLARAKGEILRVIEILIEKMPTDV
                     VDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERSHRIAVGARHGSVAL
                     YDIRTGKCQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNS
                     APQLRCIKTYQVPPVQPASPGSHNALKLARLIWTSNRNVILMAHDGKEHRFMV"
     exon            398..504
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            505..583
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            584..758
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            759..835
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            836..955
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1101
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1204
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            1205..1346
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1595
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1816
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..2012
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            2013..2227
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2997
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            2998..3086
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3087..3182
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3301
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3425
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3426..3539
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3540..3761
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3762..3948
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            3949..4066
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            4067..4216
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            4217..4299
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            4300..4399
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            4400..4504
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     exon            4505..7109
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7088..7093
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /note="hexamer: AATAAA"
     polyA_site      7109
                     /gene="Wdr7"
                     /gene_synonym="mKIAA0541; TRAG"
                     /note="major polyA site"
ORIGIN      
        1 aattgaggcc ggtgtcagct gatttactgc agcagcagcg gcggtggctc cttgcaacca
       61 ggcagggtga gggcggctac atcggcgtgg ggtccctcgg ggtcgcccac ccgggctttg
      121 cctcgctggt cctcctcgcc tacacctcct cctttgcctt ctttgcgggg gcgcccacag
      181 catcccctac agacatgatt atcgcctgag gtgaagattt gacaggtttg aaaacgccat
      241 ggcaggaaac agcctagttc tgcccattgt tctttggggc cgcaaagcac ccacacattg
      301 catttcgtca atactgttga cagatgatgg gggcacaatt gtaactggat gccacgatgg
      361 acaaatatgt ctctgggatg tttcggtaga actagaagtt aatccccgag cactgttatt
      421 tggccacaca gcatccatca cttgtttgtc aaaagcctgc gcttctgggg acaagcggta
      481 cactgtgagc gcgtctgcaa acggagagat gtgcctctgg gatgtgaacg atggcagatg
      541 tattgaattt accaagttag cctgcacaca cactggcata cagttctacc agttctctgt
      601 tgggaaccag caagagggca ggctcctctg ccatggacat taccctgaaa tcctcgttgt
      661 ggatgccacc agccttgagg tgttgtattc cttggtatcg aagatctctc cagactggat
      721 cagctccatg agcatcatcc gctctcagcg gacacaagag gacactgtgg tggcgctctc
      781 tgtgacaggt attctgaagg tgtggattgt cacctctgaa atgagtggaa tgcaggatac
      841 tgagccaata tttgaggagg aatccaaacc aatttattgt cagaattgcc aaagcatctc
      901 tttttgtgca ttcacacaga ggtcactttt ggtcgtatgc tccaaatact ggagggtgtt
      961 tgatgctggc gactactctc tgttgtgctc aggtcctagt gaaaatggac agacatggac
     1021 tggaggggac tttgtgtctg cagacaaagt catcatctgg acagaaaatg ggcagagtta
     1081 catctacaaa ctccctgcca gttgccttcc agctagtgat tcattccgca gcgacgtggg
     1141 gaaagcagtg gaaaatttga tccctcctgt gcagcatagc ctcttggatc agaaagataa
     1201 agagttggta atttgtcctc ctgttactcg gtttttctac ggatgcaagg aatatttgca
     1261 taagctacta attcagggcg attcttctgg aaggttaaat atctggaaca tagcagacat
     1321 agcagagaaa caggaagccg atgaagggct aaagatgaca acttgtatta gcttgcaaga
     1381 ggcatttgac aagctgaagc cttgccctgc tggaattatc gatcagctaa gtgtgattcc
     1441 caacagcaac gaacctctta aagtaactgc gagtgtctac ataccagcac acgggcgact
     1501 tgtttgtggc cgggaagatg gaagcatcat tattgtgcct gccacccaga cggccatagt
     1561 tcagctattg caaggagaac acatgctcag aagaggttgg ccccctcaca gaaccctccg
     1621 tggccatcgg aacaaagtca cgtgcctgct gtatccccat caggtctcag ctcggtatga
     1681 ccaaagatac ctgatatctg gaggtgtgga tttttccgtc ataatttggg acatattttc
     1741 tggagaaatg aaacatatct tctgtgttca tggtggtgag atcacacaac ttctggtccc
     1801 cccggaaaac tgtagtgcaa gagttcaaca ctgcatctgt tccgtagcca gtgaccactc
     1861 tgtaggcctc ctaagtctgc gagagaaaaa atgcatcatg ttggcgtctc gccacctctt
     1921 tcctattcag gtgatcaagt ggaggccttc cgacgactac ctggtggtgg gatgcacaga
     1981 cggctctgtg tatgtctggc agatggacac tggtgcgctg gatcgttgtg caatgggaat
     2041 cacagcagtg gagatactga acgcttgtga cgaagccgtt cctgccgctg tagactctct
     2101 tagtcatcca gcagtcaacc tgaaacaagc catgacaaga cggagtctcg ccgcccttaa
     2161 aaatatggcc caccataagc tgcaaaccct tgcaacgaac cttttggctt ctgaggcctc
     2221 tgacaagggt aatttaccta aatattccca taactccctg atggttcaag caataaagac
     2281 aaacctaaca gacccggata tccatgtgct tttctttgat gtggaagctt tgattattca
     2341 actcctgact gaagaagcct ctaggccgaa tactgcactt atttccccag agaatctgca
     2401 gaaagcatct ggcagttcag acaaaggggg ctctttccta actgggaagc gagcagcggt
     2461 tcttttccag caagtgaaag aaactatcaa agagaacata aaggaacacc ttctggatga
     2521 ggaggaggac gaggaggagg cgaggaggca gagcagggag gatagtgacc ctgagtaccg
     2581 ggccagcaag tccaagccac tgaccctact agaatacaac cttactatgg ataccgcaaa
     2641 attattcatg tcctgtctcc acgcctgggg cttgaatgaa gttctggatg aagtttgtct
     2701 cgatcgcctc ggaatgctga aaccgcactg cacggtgtcc tttggtctcc tatcgagagg
     2761 aggtcatatg tcgctgatgc ttcccggtta taatcaggct gctggaaaac tgctgcatgc
     2821 gaaagcagaa gtaggaagga agctgccagc agcggagggc gtaggcaagg gaacctacac
     2881 agtgtctcga gcggtcacca ctcagcatct gttgtccatc atatccctgg cgaatacttt
     2941 aatgagtatg accaatgcaa ctttcattgg cgatcacatg aagaagggcc ccaccaggcc
     3001 gcctagacct ggcaccccag acctctctaa ggcgagggat tcccctccac cctccagtaa
     3061 cattgtgcaa ggacagatta aacaagccgc tgcgcctgtc gtttctgctc ggtctgacgc
     3121 tgatcactct ggctctgact ctgcctctcc tgctttacct acctgtttct tagtaaatga
     3181 aggctggagc cagttagccg ccatgcactg tgttatgttg cctgacctgc tggggctgga
     3241 gagattcagg cctcctctcc tggagatgct agctcgaaga tggcaggacc gatgcttgga
     3301 ggtgagagag gctgcacagg ccctgcttct agctgagctg agaaggattg agcaggcagg
     3361 acggaaggag acgatcgaca cctgggctcc ttacttacct cagtatatgg accatgtcat
     3421 atcacctggc gtcacggcgg aagccatgca gactatggca gctgctccag atgcctcggg
     3481 cccagaagcc aaagtccagg aagaagagca tgacctggtg gatgatgaca tcactgcagg
     3541 ttgcttgtca agtgtcccac agatgaaaaa aatctccacg tcttacgaag aaagaaggaa
     3601 gcaggccacg gctattgttc tcctgggagt gataggggca gagtttggag ctgaaattga
     3661 accgccgaag ctgctgacca ggcctcgaag ctccagtcaa atccctgaag gctttggctt
     3721 gaccagcgga ggctccaact actccctggc cagacacacg tgcaaggcac tgacatatct
     3781 tctgctacag ccaccaagtc ccaagctccc tcctcatagc accatccgga gaactgccac
     3841 tgacctgatt gggcgagggt tcactgtatg ggagccctac atggatgtgt ccgctgtcct
     3901 gatggggctg ctggagctct gtgcagacgc tgagaaacaa cttgccaaca tcacaatggg
     3961 gctgcctctg agccctgcag ctgactctgc ccgctccgca aggcacgccc tgtctctcat
     4021 cgccacagcc agaccacccg ccttcatcac caccatagct aaggaggtcc acagacacac
     4081 ggcccttgca gcgaacaccc agtcccagca gagtatacac accaccaccc tggcgagggc
     4141 taaaggcgaa atcctgagag tcattgaaat tctcattgaa aagatgccca cggatgtggt
     4201 ggatcttctt gtggaggtga tggatatcat catgtactgc ctggaaggat ctttagtgaa
     4261 aaagaagggt cttcaggagt gttttccagc tatctgcagg ttctacatgg tcagctatta
     4321 tgagcgcagt cacagaatcg cagttggagc acgccatggc tcagtagccc tgtatgacat
     4381 ccggactgga aaatgtcaga caatccatgg gcacaaggga ccaatcacgg cggtgtcctt
     4441 tgctcctgat ggccgttacc ttgccaccta ctcgaacacc gacagccaca tttccttctg
     4501 gcagatgaac acctcactcc tgggaagcat tggaatgctg aactcagctc ctcagctgcg
     4561 ctgcatcaag acctaccagg tccctccagt gcagccagca tcccctggct cccacaacgc
     4621 ccttaagttg gcccggctca tctggacttc caaccggaat gttatcctca tggcccatga
     4681 tgggaaggaa caccgcttca tggtctgacc ctgctggctg ctgtcctgac tgtcagtcaa
     4741 ttctgtattg tctaggccga tgttgctctg tccttcctca gactgggctg ttgcttgctt
     4801 cctgccccct caatgccatc cagggccatg gccggtctat gtcatttgcg catgcttcat
     4861 gggggcagat tccacatggg cagcctgtcg attgaaaggc acacacatac cactcaacag
     4921 gatgcgacca ttctgtcact aggtagtttc tccctgcctg aggggacagc tagtggctcc
     4981 tggagatgtt cttgttgcct aatgcaacag aagcctggga ctcattaacc agtgtgactg
     5041 cactcccagg cctggacctg gatgctagcg ccatgcagag tcctcgttac tgaagtgact
     5101 tccctttgga tttcccagac acgctgttgt ttactaaacc tgttccatgt ttacattgct
     5161 ttctcttcct gctagcaatt gataggcagt tactcagttc catttctgag gatttagcca
     5221 tgaccttctc ggtaacatta attctgatct gaggctaatg agaaaatatt aaattacata
     5281 tatatttttc cttctagaaa agttttctag ataactagct ttttgaatgt tcatttctgg
     5341 ttcagtgtta gcagatttca tagtttaaaa tacagatcat cactactcac catgcagtga
     5401 ctatagccaa ccttctaagg ggactttcaa caaagaacca agtttaggag caagcatatt
     5461 tgtatagtgg agcatcaccc atgtgtcact aggttctcct gctcagaaaa ggcctcctcc
     5521 ccttgggctc ttcacaaccg acagttctca tgtgtacagc aatgtcacag tgggcatttc
     5581 aacctggcct tccagattat gaccagtgaa agaacaacta ggaaagcatt taagtcagca
     5641 tcctagaagt ctcctaactg tgtagacaca ttgttcagag tgtacagaaa atgtaaagac
     5701 tatcagtctg ttagaatgga cactagagtg aaagtgtcca cacttcaacc caaacttaac
     5761 tccactctcc tcttgtgtca agttacattg gtggaattgt aatagaagaa aaaactctat
     5821 aacaatgttt tatatgagtt gttcttaaat attttgatct gtattagtgg gggttgattt
     5881 gtgtgttggt tgattggtta gttacacaag attgtctatt atatacaaaa attgaaaagg
     5941 ggttattgaa ttcagagaaa atatataata ttaacagagg aactaaaatg gtgagagcat
     6001 ttagtcttaa actcgtagac tgtcgaagtg tatgtaatat gtagaaaagt agaatcaagg
     6061 tccgtgaatg aatacatagt ttacagtcct tcaaagaaca tgtgaagaag ctaatgccct
     6121 cagtgtcttt tgacgagcaa tgtatgttat ttttcattga tggcaactct atactgtctc
     6181 ttgggttttg acattggggt tctttcaaaa gtgaatttat ttcacatgca tgtatatcgt
     6241 acttataatg attatatatg tagcttccaa gaaagaaacc aagaactgta cagtgtagac
     6301 ttttgtgaac atactactgt atttgatgta gatggagaaa tgtccagcag cctctagagt
     6361 ctgcgtctgc tcagcgcagg tttactgtat gaacttcaga gcgagaagtt aaaccagttc
     6421 aaatggtgag caaacacaga ctttaagggg ttttttgttt ttgttttttt aagcaaaatg
     6481 ttccctacat tttgaaagag atgggggact ggaggtcaat gacagatggt atcacatcat
     6541 agagatgggc acaaagcaat gaggtcacaa actctggtca caggtccagg ccagtccttc
     6601 cgtgccctgt gtgtatattc agaagagcac aaggactata aaactccatg ctggaagagt
     6661 cactaaccga tagagtcatt tcactctcat gctggaagag tcactaacgg atagagtatc
     6721 atttcactct cattaaaata atgctcgctc tggctgtttg acatccatag tccccagctt
     6781 cacctcagct tggatccctc aacactgagg tgaaccttgc attgtcatcc cagtaccctt
     6841 gtagtgtttt attgattttg ttgacacagc acttggaccc gtccctgtaa atataaagac
     6901 atatgtggct tcactggtaa cttacaagca aaaggtgaca tgatgcgaca cttgtgtgaa
     6961 aatggtgtca tgtttgaaac tgcatatagt gaatgagtta aaatgtctcg tctcctacga
     7021 cattctggct gactccatct agtagatcct gtgtgcgttt aaaattgctg tgtacatact
     7081 tgtgttaaat aaaactgaag tgtactaaa
//
