LOCUS       NM_029453               3817 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WD repeat domain 64 (Wdr64), mRNA.
ACCESSION   NM_029453 XM_001472727 XM_001474997
VERSION     NM_029453.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3817)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124366.4 and AC122854.4.
            
            On or before Nov 18, 2009 this sequence version replaced
            XM_001472727.1, XM_001474997.1, NM_029453.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-339               AC124366.4         140613-140951
            340-470             AC124366.4         147965-148095
            471-573             AC124366.4         159299-159401
            574-677             AC124366.4         162298-162401
            678-707             AC122854.4         3502-3531
            708-818             AC122854.4         5224-5334
            819-1033            AC122854.4         7618-7832
            1034-1168           AC122854.4         10317-10451
            1169-1248           AC122854.4         22381-22460
            1249-1388           AC122854.4         34359-34498
            1389-1515           AC122854.4         42777-42903
            1516-1664           AC122854.4         45841-45989
            1665-1788           AC122854.4         48341-48464
            1789-1964           AC122854.4         51008-51183
            1965-2141           AC122854.4         54410-54586
            2142-2272           AC122854.4         64313-64443
            2273-2374           AC122854.4         68739-68840
            2375-2444           AC122854.4         70028-70097
            2445-2481           AC122854.4         70952-70988
            2482-2618           AC122854.4         71796-71932
            2619-2724           AC122854.4         73918-74023
            2725-2783           AC122854.4         78052-78110
            2784-2893           AC122854.4         79136-79245
            2894-3082           AC122854.4         84689-84877
            3083-3188           AC122854.4         87511-87616
            3189-3269           AC122854.4         89363-89443
            3270-3368           AC122854.4         90847-90945
            3369-3817           AC122854.4         94121-94569
FEATURES             Location/Qualifiers
     source          1..3817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 81.71 cM"
     gene            1..3817
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /note="WD repeat domain 64"
                     /db_xref="GeneID:75820"
                     /db_xref="MGI:MGI:1923070"
     exon            1..339
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..3449
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /codon_start=1
                     /product="WD repeat-containing protein 64"
                     /protein_id="NP_083729.2"
                     /db_xref="CCDS:CCDS48460.1"
                     /db_xref="GeneID:75820"
                     /db_xref="MGI:MGI:1923070"
                     /translation="MDAKDEKRFNLALQINNFKASLVEFNKLVEQTTAQKKEERAGIF
                     IPKEDSIDYDKFYTSVQQIFGPEVKNQDVKCFYRKLCNNPDAAFDWCEIFGYFSTDED
                     SLTSQMDEENLVFLVSRKQRIVIAGSRRRDVIKCIVKVPQLDLLITASQKGLITVFNS
                     QMRAQTSTNVTDTSWITGCDYLGQLKRIVATTERTIIVWDYKAQGSSQEHYFVIKPMD
                     HCLLCVCVVPLPDQLCRDDILLGDDGGFVNKFTVSSDDFGLKQAKTKKKLQTQVLDSK
                     NFKSVKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLEDNLPVREFAMPR
                     GANSFCYCGKANVIVTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKEQHVI
                     SLSSAKVFRVWDIQTLSVLQVFHDSQGGPGDMQIYSMVYDANHGMLITGSGVIDMYPL
                     TRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESVIKVWELETGLQIYQILDPHG
                     LSIELTCAAIDESGYLFATGAYNGTVKIWDFGSGQEMKMMPEGKDWVEEEHGLMRLFF
                     LKPQVKQQHLILALERNGTIKIIQGKEDDIFLTVIWELPDAMPYLQYGSHIVHLKMST
                     KERTMAIPFPDVELIVQKTSQQTNYSPIVDVDVNCIDVFQTEGYNLIACGTTNGMIIL
                     WNFIAASVKEIYRPEDCFSTDPELDPKRFRINDIMFLFRSPECVRRSSQDSICSSTQC
                     DSSKGPQSSKGSKQSIHDADVKGEHTDMVGEQQSASRKQPVPISFVEPQPPLLVSAHE
                     DGHLRLWTLEGKLIKDMLPFTKHSAISLTSLYTDSCCRVLLAGNVEGHVILCSISSFM
                     DPPHDEKKFKQLLSWRAHSLEIIQVIYVEEKQLVLTASIDGSVRIWNSTSGHYCGYFG
                     QRRMFDLSQTSDFILPCDVNEYPIEIKEESKFTEKTQKYEYPLIFDRERWKKMSSMSL
                     LFKRPPLSPFEVQHDFKFFKSLSSPKIRRYALEGFLTENREAGIVFGSLPIYRVPSPT
                     SLRFLPLIGSEVQRDSVEGVYMKKKHDKSRRKSLKRNLVPQINLASSFFPTTPK"
     exon            340..470
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            471..573
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            574..677
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            678..707
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            708..818
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1033
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1168
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1248
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1388
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1515
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1664
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1788
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1964
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2141
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2272
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2374
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..2444
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2445..2481
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2618
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2619..2724
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2725..2783
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2784..2893
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2894..3082
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3083..3188
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..3269
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3270..3368
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3369..3817
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3791..3796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3817
                     /gene="Wdr64"
                     /gene_synonym="4930415O10Rik; 4930511H01Rik"
                     /note="major polyA site"
ORIGIN      
        1 agctgtcctc ctgctaacct gctagaaaca actcttactc cttgttcctc tagaacaggg
       61 atataaaagt cagaggaatg agacctaggg caaaagttga aacagcagac acattataag
      121 aactagaagc atttccacat tggcaagttt gcagtattat ttctgcgcag aaataagaga
      181 ctccctatgt ctgtatggat gccaaggatg agaagcggtt caacctcgcg ctgcagatca
      241 acaatttcaa agcgtccttg gttgagttca ataaactggt tgaacagaca acagcccaga
      301 aaaaggaaga aagagcaggc atatttatac caaaagaaga ttcaatcgac tatgataagt
      361 tttacacctc ggtacagcaa atctttggcc ctgaagtgaa aaatcaagat gtgaaatgtt
      421 tttacaggaa gctctgcaac aatcctgacg cagctttcga ctggtgtgag atctttggat
      481 acttctccac tgatgaagat tctcttactt cgcagatgga tgaagaaaat ttggtttttc
      541 ttgtgtctag aaaacagcga attgtgattg caggcagtag acgacgtgat gtgatcaaat
      601 gcattgtgaa ggtcccacag ctggatttat tgataacagc atctcagaaa ggattaataa
      661 ctgtcttcaa cagccagatg agggctcaga ccagcaccaa cgttacagat acctcctgga
      721 ttacaggctg cgattacctt ggccagctaa agcgaattgt tgccaccact gagaggacca
      781 ttattgtctg ggattataaa gctcaaggga gcagccagga gcactacttt gtcatcaagc
      841 ccatggacca ctgcctgctc tgtgtgtgtg tggtgcccct gcctgatcag ctctgcaggg
      901 atgacattct cctgggagat gatggtgggt ttgtgaacaa gttcacggtg agcagtgatg
      961 actttggatt aaagcaggca aagaccaaaa agaaattaca aactcaggtc cttgactcga
     1021 agaactttaa aagtgttaaa aggaaactgc ataatgattg ggttatgaaa atcagataca
     1081 ttccagctct caattgcttt ggatcctgtt ccttagacag cgtccattcc ttagtcttgg
     1141 aatccttgaa gagacttgaa gacaatttgc ctgtcagaga atttgccatg ccaagaggag
     1201 ccaacagttt ctgctactgc ggtaaagcaa atgtgatcgt cactggagga gatgataaag
     1261 tcctccggct gtggcacccc aacatcagca ctaagccagt cgggaagctg gtggggcaca
     1321 tgttcagcat cactgagatc gtaagcaatg agaaggagca acacgtcatt agcctttcct
     1381 ctgcaaaggt cttccgggtg tgggatatac agactctgtc tgtactgcaa gtcttccacg
     1441 atagccaagg tgggccagga gacatgcaga tttactctat ggtatatgat gccaaccatg
     1501 gcatgctcat tacaggatct ggtgtaatag acatgtatcc tttgaccagg atgatacagg
     1561 acacaaagca ggttcctcac actcatgaac gagaagtcaa cgtcacgctt tacaacaagt
     1621 acttccacca agtgctcacg gtctgctcag agtctgtaat caaggtatgg gaacttgaga
     1681 ctggtctcca aatataccaa attctagacc ctcatggcct cagtattgaa ctaacctgtg
     1741 cagctattga tgaaagtgga tatctttttg ctacaggagc atataatgga acagttaaga
     1801 tctgggactt tggcagtggg caggaaatga aaatgatgcc cgaagggaaa gactgggtgg
     1861 aggaggaaca tggcctgatg cgcctgtttt tcctcaagcc ccaagtgaag caacagcacc
     1921 tcatcctcgc cttggagcgc aatggaacta tcaagattat ccagggaaag gaagatgata
     1981 tcttcctcac ggtgatatgg gagctgccgg acgccatgcc ttacctacaa tatgggagcc
     2041 atattgtaca tctgaagatg tcaactaaag aaaggacaat ggccattcct ttcccagacg
     2101 ttgagttaat cgtccagaaa acctcccaac aaactaatta tagtcctatt gtcgatgtgg
     2161 atgtgaactg cattgatgta tttcaaacag agggatataa tctgatagcg tgtggcacaa
     2221 caaatggcat gataatctta tggaatttca tagcagcttc tgtcaaagaa atataccggc
     2281 ccgaggattg cttctctaca gatcctgagt tggatcccaa acgctttcga attaatgaca
     2341 taatgttcct cttccgaagt cctgaatgtg taaggagatc aagtcaggat tctatatgct
     2401 catcaaccca atgtgattca agcaagggtc cacagagtag caaggggagt aagcaaagca
     2461 ttcatgacgc cgatgtcaaa ggtgagcata cagacatggt gggagagcag cagtcagcaa
     2521 gcaggaaaca gcctgtaccc atcagcttcg tggaaccaca gcctcctctc ctggtctctg
     2581 cgcacgagga tggacacctc cgtttgtgga cgctggaggg gaagctcata aaagacatgc
     2641 tgcccttcac gaagcactct gccatttccc tgacgtcact atacaccgac tcatgctgca
     2701 gggtactact ggctgggaat gtggaaggac acgttatcct ttgcagtatt agttccttca
     2761 tggatccacc tcacgatgaa aagaaattca agcagctgct ttcctggcgt gcccattctt
     2821 tagaaattat tcaagtgatc tacgtggaag aaaagcagct ggtgcttact gcctccattg
     2881 atggctcagt gaggatctgg aattccacca gtggtcatta ctgtgggtat tttggacaac
     2941 gaagaatgtt tgacctttcc caaacaagtg acttcatttt gccttgtgat gttaatgaat
     3001 atcccataga gattaaagaa gaaagcaagt tcacagagaa gacacaaaaa tatgaatatc
     3061 ctctgatatt tgaccgtgaa agatggaaaa aaatgagctc aatgtctttg ctttttaagc
     3121 gaccacctct cagtcccttt gaagtgcaac atgattttaa atttttcaag tctctttctt
     3181 ctccaaagat tcgccgatat gctttggaag gtttcctgac agaaaaccga gaggcaggga
     3241 ttgtttttgg ttctctgcct atatacaggg taccaagtcc cacgagtcta agattccttc
     3301 cccttattgg ctctgaagta caaagagatt cagtggaggg tgtttatatg aagaagaaac
     3361 atgacaaatc acggaggaaa agcctgaaaa ggaatttggt tccacagata aatctggctt
     3421 catccttctt cccaaccaca cccaagtgaa gaggaaacct cagaactggc tgctgtacag
     3481 gaggccacaa ggtccagatc tagtcaagat gaggatgcca caccaccaga tggttacacg
     3541 tctctcttac agaccatcct gataatggag gctgctcaag gggctctggt gacctcacag
     3601 ggtctgcagc cagtctgcca actttttaca catagaaaaa cataacaaac gggcaatgtc
     3661 tctcatcatt gtcaacaaga tctcacaagg acataaacaa aatcagtagc ctgggtagac
     3721 ccaaatgata cggttagtgg tgattagctt tgtacctatc tccacctgtt caccccaacc
     3781 cataaccaga attaaagcgt gcgcagtaag aggcaaa
//
