LOCUS       NM_001408660            4790 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat domain 62 (Wdr62), transcript variant 3,
            mRNA.
ACCESSION   NM_001408660 XM_006539875
VERSION     NM_001408660.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4790)
  AUTHORS   Xu,D., Zhi,Y., Liu,X., Guan,L., Yu,J., Zhang,D., Zhang,W., Wang,Y.,
            Tao,W. and Xu,Z.
  TITLE     WDR62-deficiency Causes Autism-like Behaviors Independent of
            Microcephaly in Mice
  JOURNAL   Neurosci Bull 39 (9), 1333-1347 (2023)
   PUBMED   36571716
  REMARK    GeneRIF: WDR62-deficiency Causes Autism-like Behaviors Independent
            of Microcephaly in Mice.
REFERENCE   3  (bases 1 to 4790)
  AUTHORS   Meziane,H., Birling,M.C., Wendling,O., Leblanc,S., Dubos,A.,
            Selloum,M., Pavlovic,G., Sorg,T., Kalscheuer,V.M., Billuart,P.,
            Laumonnier,F., Chelly,J., van Bokhoven,H. and Herault,Y.
  TITLE     Large-Scale Functional Assessment of Genes Involved in Rare
            Diseases with Intellectual Disabilities Unravels Unique
            Developmental and Behaviour Profiles in Mouse Models
  JOURNAL   Biomedicines 10 (12), 3148 (2022)
   PUBMED   36551904
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4790)
  AUTHORS   Wang,Y.S., Chen,C., Ahmad,M.J., Chen,F., Ding,Z.M., Yang,S.J.,
            Chen,Y.W., Duan,Z.Q., Liu,M., Liang,A.X., He,C.J., Hua,G.H. and
            Huo,L.J.
  TITLE     WDR62 regulates mouse oocyte meiotic maturation related to p-JNK
            and H3K9 trimethylation
  JOURNAL   Int J Biochem Cell Biol 144, 106169 (2022)
   PUBMED   35093571
  REMARK    GeneRIF: WDR62 regulates mouse oocyte meiotic maturation related to
            p-JNK and H3K9 trimethylation.
REFERENCE   5  (bases 1 to 4790)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4790)
  AUTHORS   Xu,D., Zhang,F., Wang,Y., Sun,Y. and Xu,Z.
  TITLE     Microcephaly-associated protein WDR62 regulates neurogenesis
            through JNK1 in the developing neocortex
  JOURNAL   Cell Rep 6 (1), 104-116 (2014)
   PUBMED   24388750
REFERENCE   7  (bases 1 to 4790)
  AUTHORS   Bogoyevitch,M.A., Yeap,Y.Y., Qu,Z., Ngoei,K.R., Yip,Y.Y.,
            Zhao,T.T., Heng,J.I. and Ng,D.C.
  TITLE     WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein
            required for spindle maintenance and timely mitotic progression
  JOURNAL   J Cell Sci 125 (Pt 21), 5096-5109 (2012)
   PUBMED   22899712
  REMARK    GeneRIF: A key role for WDR62 in metaphase spindle organization,
            required for normal mitotic progression.
REFERENCE   8  (bases 1 to 4790)
  AUTHORS   Passemard,S., El Ghouzzi,V., Nasser,H., Verney,C., Vodjdani,G.,
            Lacaud,A., Lebon,S., Laburthe,M., Robberecht,P., Nardelli,J.,
            Mani,S., Verloes,A., Gressens,P. and Lelievre,V.
  TITLE     VIP blockade leads to microcephaly in mice via disruption of
            Mcph1-Chk1 signaling
  JOURNAL   J Clin Invest 121 (8), 3071-3087 (2011)
   PUBMED   21737879
REFERENCE   9  (bases 1 to 4790)
  AUTHORS   Nicholas,A.K., Khurshid,M., Desir,J., Carvalho,O.P., Cox,J.J.,
            Thornton,G., Kausar,R., Ansar,M., Ahmad,W., Verloes,A.,
            Passemard,S., Misson,J.P., Lindsay,S., Gergely,F., Dobyns,W.B.,
            Roberts,E., Abramowicz,M. and Woods,C.G.
  TITLE     WDR62 is associated with the spindle pole and is mutated in human
            microcephaly
  JOURNAL   Nat Genet 42 (11), 1010-1014 (2010)
   PUBMED   20890279
REFERENCE   10 (bases 1 to 4790)
  AUTHORS   Bilguvar,K., Ozturk,A.K., Louvi,A., Kwan,K.Y., Choi,M., Tatli,B.,
            Yalnizoglu,D., Tuysuz,B., Caglayan,A.O., Gokben,S., Kaymakcalan,H.,
            Barak,T., Bakircioglu,M., Yasuno,K., Ho,W., Sanders,S., Zhu,Y.,
            Yilmaz,S., Dincer,A., Johnson,M.H., Bronen,R.A., Kocer,N., Per,H.,
            Mane,S., Pamir,M.N., Yalcinkaya,C., Kumandas,S., Topcu,M.,
            Ozmen,M., Sestan,N., Lifton,R.P., State,M.W. and Gunel,M.
  TITLE     Whole-exome sequencing identifies recessive WDR62 mutations in
            severe brain malformations
  JOURNAL   Nature 467 (7312), 207-210 (2010)
   PUBMED   20729831
  REMARK    GeneRIF: In mice and humans, WDR62 transcripts and protein are
            enriched in neural progenitors within the ventricular and
            subventricular zones.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149067.3.
            
            On Jun 21, 2022 this sequence version replaced XM_006539875.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-255               AC149067.3         88855-89109         c
            256-347             AC149067.3         83801-83892         c
            348-410             AC149067.3         82647-82709         c
            411-468             AC149067.3         81026-81083         c
            469-639             AC149067.3         80306-80476         c
            640-777             AC149067.3         79378-79515         c
            778-960             AC149067.3         78848-79030         c
            961-1121            AC149067.3         76481-76641         c
            1122-1311           AC149067.3         73781-73970         c
            1312-1449           AC149067.3         71311-71448         c
            1450-1628           AC149067.3         69987-70165         c
            1629-1720           AC149067.3         66755-66846         c
            1721-1846           AC149067.3         64504-64629         c
            1847-1914           AC149067.3         62885-62952         c
            1915-2036           AC149067.3         62682-62803         c
            2037-2112           AC149067.3         61015-61090         c
            2113-2224           AC149067.3         60232-60343         c
            2225-2288           AC149067.3         60091-60154         c
            2289-2411           AC149067.3         59377-59499         c
            2412-2545           AC149067.3         58478-58611         c
            2546-2598           AC149067.3         56315-56367         c
            2599-2817           AC149067.3         53986-54204         c
            2818-2883           AC149067.3         53172-53237         c
            2884-3011           AC149067.3         52532-52659         c
            3012-3115           AC149067.3         52130-52233         c
            3116-3223           AC149067.3         51733-51840         c
            3224-3355           AC149067.3         51445-51576         c
            3356-3470           AC149067.3         51097-51211         c
            3471-3600           AC149067.3         50844-50973         c
            3601-3652           AC149067.3         50713-50764         c
            3653-4306           AC149067.3         49930-50583         c
            4307-4443           AC149067.3         49277-49413         c
            4444-4790           AC149067.3         48837-49183         c
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 17.34 cM"
     gene            1..4790
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /note="WD repeat domain 62"
                     /db_xref="GeneID:233064"
                     /db_xref="MGI:MGI:1923696"
     exon            1..255
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..4707
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /note="isoform 3 is encoded by transcript variant 3; WD
                     repeat-containing protein 62"
                     /codon_start=1
                     /product="WD repeat-containing protein 62 isoform 3"
                     /protein_id="NP_001395589.1"
                     /db_xref="GeneID:233064"
                     /db_xref="MGI:MGI:1923696"
                     /translation="MAALAAGGYTRSDTIEKLSSVMAGVPARRNQSSPPPAPPLCLRR
                     RTRLAAAPEDTVQNRVTLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVVLNPKENK
                     QQHIFNTTRKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKTQVAEMLGHKYGVAC
                     VAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGN
                     RHVRFWFLEASTEAKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGNTFCVSYSG
                     LLCQFNEKRVLDKWINLKVSLSSCLCVSDELIFCGCTDGIVRIFQAHSLLYLTNLPKP
                     HYLGVDVAHGLDSSFLFHRKAEAVYPDTVALTFDPVHQWLSCVYKDHSIYIWDVKDID
                     EVSKIWSELFHSSFVWNVEVYPEFEDQRACLPSGTFLTCSSDNTIRFWNLDSASDTRW
                     QKNIFSDSLLKVVYVENDIQHLQDLSHFPDRGSENGTPMDMKAGVRVMQVSPDGQHLA
                     SGDRSGNLRIHELHFMDELIKVEAHDAEVLCLEYSKPETGVTLLASASRDRLIHVLNV
                     EKNYNLEQTLDDHSSSITAIKFAGTRDVQMISCGADKSIYFRSAQQASDGLHFVRTHH
                     VAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVSGKQKKCYKGSQGDEGSLLKVHVD
                     PSGTFLATSCSDKSISLIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVF
                     IWHLGPEITTCMKQHLLEINHQEQQQQPKDQKWSGPPSQETYASTPSEIRSLSPGEQT
                     EDEMEEECEPEELLKTPSKDSLDPDPRCLLTNGKLPLWAKRLLGDDDVADSSAFHAKR
                     SYQPHGRWAERAEQEPLKTILDAWSLDSYFTPMKPENLQDSVLDSVEPQNLAGLLSEC
                     SLGNGHTSPGEGLVSYLLHPELGSPKEDNRGHPSYLPLQREATEASELILCSPEAEVS
                     LTGMHREYYEEETEAGPEDQQGDTYLRVSSVSSKDQSPPEDSGESEAELECSFAAAHS
                     SAPQTDPGPHLTMTAGKPEYPSTEELSQPELPGLGNGSLPQTPEQEKFLRHHFETLTD
                     APTEELFHGSLGDIKISETEDYFFNPRLSISTQFLSRLQKTSRCPPRLPLHLMKSPEA
                     QPVGQGGNQPKAGPLRAGTGYMSSDGTNVLSGQKAEETQEALSLLVPPLSGLTSCVPP
                     SSVPPTDRKPPTPTSVLTTGREQSISAPSSCSYLESTTSSHAKTTRSISLGDSEGPVT
                     AELPQSLHKPLSPGQELQAIPTTVALTSSIKDHEPAPLSWGNHEARASLKLTLSSVCE
                     QLLSPPPQEPPITHVWSQEPVDVPPSMAVTVASFCAPSPVDMSTLGLHSSMFLPKTSA
                     SGPLTPPAHLQLLETRSRVPGSTAALLEPTPDASGVIADSPGHWDTEVPTPELLGSVE
                     SVLHRLQTAFQEALDLYRMLVSSSQLGPEQQQAQTELASTFHWILNQLEASNCMAAAN
                     LAPPQTLPSPDPLSLPTLCPLASPNLQALLEHYSELLVQAVRRKARGD"
     exon            256..347
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            348..410
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            411..468
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            469..639
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            640..777
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            778..960
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1121
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1311
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1449
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1628
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1720
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1846
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..1914
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            1915..2036
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2112
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2224
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2288
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..2411
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2545
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2546..2598
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2599..2817
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2818..2883
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            2884..3011
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3012..3115
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3116..3223
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3224..3355
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3356..3470
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3471..3600
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3601..3652
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            3653..4306
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            4307..4443
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     exon            4444..4790
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4765..4770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /note="hexamer: AATAAA"
     polyA_site      4790
                     /gene="Wdr62"
                     /gene_synonym="2310038K02Rik; b2b1508Clo"
                     /note="major polyA site"
ORIGIN      
        1 ggccattcgc tattcgagtg ggtgctggct acaggcggct gttaagaagc gtaacggaca
       61 ctggtctccg acagcatgat ggctgcctta gcggccggag gttatacgcg gagtgacacg
      121 atagaaaagc tgtcctctgt catggcggga gttccggcgc ggagaaacca gtcctccccg
      181 cctcctgccc caccgctctg cctccggcgg cggacgcgac tcgcggcggc tcccgaggac
      241 actgtgcaga accgggtgac acttgagaag gtgcttggca tcacagccca gaacagcagc
      301 gggctaacct gtgaccctgg cacaggccat gtggcctact tagcagggtg cgtggtggtg
      361 gtcttgaacc ccaaggagaa caagcagcag catatattta acacaaccag gaagtccctg
      421 agtgctctgg ccttctcccc agatgggaag tacatagtga caggagagaa tggacaccgg
      481 ccagctgtgc gcatctggga tgtggaggag aagactcaag tggcagagat gctgggccac
      541 aagtatggtg tggcctgtgt ggctttctca cccaatatga agcacatcgt gtccatgggc
      601 taccaacatg acatggtcct caatgtttgg gattggaaga aagacattgt ggtggcttcc
      661 aacaaggtgt catgtagagt catcgctctc tccttctctg aggacagcag ctattttgtc
      721 accgttggga atcggcatgt gaggttttgg ttcttagaag cctctactga ggccaaggta
      781 accagcacag tgcccctggt aggacgctca ggcatcctgg gtgagctgca caacaatatc
      841 ttttgtggcg tggcctgcgg ccggggccgg atggcaggca ataccttctg tgtgtcctac
      901 tctggcctcc tctgccagtt caatgagaaa agggtgctgg acaagtggat caacctgaag
      961 gtctccttgt cttcctgcct gtgtgtcagt gacgagttga tcttctgtgg atgcacagac
     1021 gggatagtcc gcatcttcca ggcccacagc ctactctacc tcaccaacct gcccaaacca
     1081 cactacctgg gagtggacgt ggcccacgga ctggactcca gcttcctctt ccacagaaaa
     1141 gcagaagcag tctacccaga tacagtggcc ctgacctttg accccgtcca ccagtggctg
     1201 tcctgtgttt acaaagacca cagcatctac atctgggatg tcaaggacat tgatgaagtc
     1261 agcaagatat ggtcagagct cttccacagc tcctttgtct ggaatgtaga ggtgtaccct
     1321 gaatttgaag accagagagc ttgcctgccg tccgggactt ttctgacttg ttcctcagac
     1381 aataccatcc gcttctggaa tttggatagc gcctctgaca ctcgatggca aaagaacatc
     1441 ttcagcgatt ctctgctgaa ggtggtctat gtagagaatg acatccagca cctgcaggac
     1501 ctgtctcact tcccagaccg gggcagtgag aacggcactc ccatggatat gaaagctggg
     1561 gttcgagtca tgcaggtcag tcctgacggc cagcacttgg cttcaggcga ccgcagtgga
     1621 aatctgagga tccacgagct gcacttcatg gatgagctga tcaaggtgga ggcccacgat
     1681 gctgaggtgc tgtgcctgga gtactccaag cctgagacag gagtgacttt gctggcttca
     1741 gccagtcggg acagactcat ccatgtgtta aacgtggaga agaactacaa cctggagcag
     1801 accctggacg accactcctc ctccatcaca gccattaagt ttgctggcac cagagatgtc
     1861 cagatgatca gttgtggagc tgacaagagc atctactttc gcagtgccca gcaggcctcg
     1921 gatggactgc actttgtccg tacccaccac gtagcagaga agaccacctt gtatgacatg
     1981 gatatcgaca tcacacagaa gtatgtggca gtggcctgcc aggaccgcaa cgtaagggtc
     2041 tacaacaccg tgagtgggaa acagaagaag tgctacaagg gttcccaggg cgacgaaggg
     2101 tccctgctga aggtccacgt ggacccctca ggcaccttcc tggccacaag ctgctctgac
     2161 aaaagcatct ccttgattga cttttactcg ggcgagtgtg ttgccaagat gtttggccat
     2221 tcggaaattg tcactggcat gaagttcacc tacgactgcc gccacttgat cacagtatct
     2281 ggagacagct gtgtgttcat ctggcacctg ggcccggaga tcaccacctg catgaagcag
     2341 cacttgctgg agatcaacca ccaggagcag cagcagcagc ccaaggacca gaagtggagt
     2401 ggccctccca gccaggagac atatgcatcc acaccaagtg agattcgttc cctgagccct
     2461 ggagagcaga cagaggatga gatggaggag gaatgtgagc cagaagagtt gctgaaaaca
     2521 ccatccaaag acagcttgga cccagatcct cgatgcctgc tgacaaatgg caagctgcca
     2581 ctctgggcaa agcggctgct aggggatgat gatgtggcag acagctcagc tttccacgcc
     2641 aagcgcagct accagccaca tggccgttgg gcagagcggg ctgagcagga acccctcaag
     2701 accatcctgg atgcctggag cctggattcc tactttacac ccatgaagcc tgaaaatctc
     2761 caagactctg ttctggactc agtagagcca cagaacctgg caggcctgct aagtgagtgt
     2821 tcactcggta atggacacac gtctccggga gaaggcttgg tgagctacct acttcaccca
     2881 gagttaggga gtcccaaaga ggacaaccga ggccacccct cctacctgcc tctacagagg
     2941 gaagccaccg aggcaagcga actcatcctc tgctccccag aggcggaagt gtcacttaca
     3001 gggatgcaca gggagtatta tgaggaggag acagaggcag gacctgaaga ccagcaaggc
     3061 gacacctatc tcagggtctc ttccgtcagt tcaaaggatc agagcccccc tgaggactca
     3121 ggggagtcag aggctgaact ggagtgcagc tttgccgccg cccacagctc agctcctcaa
     3181 acggaccctg gccctcacct caccatgaca gcaggtaagc cagagtaccc aagtacagaa
     3241 gagctttccc agcctgagct gccaggcttg ggcaatggct ccttacccca gacacctgag
     3301 caggagaagt tcctccgcca ccattttgag acacttactg atgcccctac tgaagagctc
     3361 tttcatggat ccctgggaga cataaagatc tcagagactg aggactattt cttcaatccc
     3421 cggctgagca tatccaccca gttcctctcc cgcctccaga agacctccag gtgccctccc
     3481 cgactgcccc tgcaccttat gaagtctcca gaggctcagc ctgtgggcca agggggcaac
     3541 cagcccaaag cagggcccct gagagcaggt actggctaca tgtcctcaga tgggaccaac
     3601 gtcctctctg ggcagaaggc tgaagaaact caagaggcct tgagtctact ggtccctccc
     3661 ctctcaggcc tgacatcctg tgtccctcct tcctcggtgc cacccacaga caggaagcct
     3721 ccaacaccca catctgtact gaccacaggc cgggagcaaa gtatctccgc cccatcttcg
     3781 tgttcttacc tggagtccac aacgagctca catgccaaga cgacacgcag catctctctt
     3841 ggggacagtg agggccctgt gacagctgag ctaccccagt cacttcacaa gcccttatcc
     3901 cctggccagg aactccaagc catccccact acagtggcac tgacctccag catcaaagac
     3961 cacgagcctg caccgctttc ctggggcaac catgaggccc gagccagcct gaaactgacc
     4021 ttatccagtg tctgtgagca gctgctctct ccacctccac aggagccacc catcacccat
     4081 gtgtggtctc aggaacctgt ggatgtccca cctagtatgg cagtcacagt agccagcttc
     4141 tgtgcaccca gccctgtaga catgagcacc ctgggactcc acagttctat gtttctccca
     4201 aagacctcag cctctgggcc cctaacccct cctgcccacc tccaacttct agagaccagg
     4261 tctagggtgc ctggcagcac tgctgctctc ctggagccca cccccgatgc atcaggtgtg
     4321 atcgcagaca gccctggaca ctgggacaca gaagtcccta ccccagaact cctaggcagt
     4381 gtggaatcag tcttgcacag gctgcagact gccttccaag aagctcttga cctttaccgc
     4441 atgctggtct ccagcagcca gctgggtcct gagcagcagc aggcacagac cgagctggcc
     4501 tccaccttcc actggatcct caaccagcta gaagccagca actgtatggc tgcagctaac
     4561 ttggccccac cccagacact gcctagccca gaccctctgt ccctacctac actttgtccc
     4621 ctggccagcc caaacctgca ggccctgctg gaacactact cagagttgct ggtgcaagca
     4681 gtgaggagga aggcaagggg tgactgagaa cctgaagccc ctctaccaaa gccccgctgc
     4741 cctggagaaa tagatttgta aaccaataaa ctgacagttg tttcctggaa
//
