LOCUS       NM_001399294            1491 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat domain 53 (Wdr53), transcript variant 3,
            mRNA.
ACCESSION   NM_001399294 XM_006522510
VERSION     NM_001399294.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1491)
  AUTHORS   Rutkowski,T.P., Purcell,R.H., Pollak,R.M., Grewenow,S.M.,
            Gafford,G.M., Malone,T., Khan,U.A., Schroeder,J.P., Epstein,M.P.,
            Bassell,G.J., Warren,S.T., Weinshenker,D., Caspary,T. and
            Mulle,J.G.
  TITLE     Behavioral changes and growth deficits in a CRISPR engineered mouse
            model of the schizophrenia-associated 3q29 deletion
  JOURNAL   Mol Psychiatry 26 (3), 772-783 (2021)
   PUBMED   30976085
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126265.3.
            
            On Jan 6, 2022 this sequence version replaced XM_006522510.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.982471.1,
                                           SRR7345562.2843468.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-370               AC126265.3         122030-122399
            371-866             AC126265.3         126594-127089
            867-1491            AC126265.3         131230-131854
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 22.47 cM"
     gene            1..1491
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /note="WD repeat domain 53"
                     /db_xref="GeneID:68980"
                     /db_xref="MGI:MGI:1916230"
     exon            1..370
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            371..866
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             387..1463
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /codon_start=1
                     /product="WD repeat-containing protein 53"
                     /protein_id="NP_001386223.1"
                     /db_xref="GeneID:68980"
                     /db_xref="MGI:MGI:1916230"
                     /translation="MAVKWTGGHSSSILCLNANKDGLVASGGEGGDLVAWGEDGTPLG
                     HMQLEGADDVTSVLFSASCPTKLYASHGETISVLDVRSLKGSLDHFHVNEEEINCLSL
                     NETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQ
                     VMLWSLQKARPVWITNLQEDETEETEGPQTPGRLLNPALAHSVSVASCGNIFSCGAED
                     GKVRIFRVMGVKCERELGFKGHTLGVSQVCFLPESSLLLTGGNDGRIRLWDVSGKMEK
                     LQKSPARHIHRKKAKRAACPTQGGNSRAPGAEDEGHAKILPKLDIEHGEKVNWLLSTK
                     IKGNKSILVADQTSCVSVYPLNEL"
     exon            867..1491
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1468..1473
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1491
                     /gene="Wdr53"
                     /gene_synonym="1500002B03Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaagcccagg tatgaggctg ttggccagcg gggttcggat ctgttcgcaa gtgctttttt
       61 tctgtttttc ctctaatggc cttgactcgg ctctccttgg cctctcttcc tacggagttt
      121 cccgtctcac ttggtttctg ctccctctct aactttgttc acgacacttc ccttttttgc
      181 tagccaattc ttagatcctt caccttcagg tcgcttggat caatttcctt tccctttgcg
      241 cagttgagga cctcttgtcg tggtcaggtt agatccattt tattatattt tatttttttt
      301 taccttgaga aattgacatc ttcttttcct ggctagcgcc gtaggggact caccagaacc
      361 cattctcaaa aatttcaaag gccatcatgg cagtcaagtg gactggtgga cattcttctt
      421 caatcctttg cctgaatgca aataaagacg ggctggtggc ttcaggagga gagggtggag
      481 accttgtggc ttggggtgaa gatgggaccc cgttaggaca catgcaattg gaaggggctg
      541 atgatgttac cagcgtcttg ttttctgcct cctgtcccac caagctctat gcctcccatg
      601 gagaaaccat cagtgtacta gatgtcaggt ctcttaaagg gtccctggac cacttccatg
      661 tgaatgagga agaaatcaac tgtctttcat taaatgaaac tgaaagtctg ctggcttcgg
      721 ctgatgactc tggggcaatt aaaatcctgg acttggaaaa gaagaaagtt accagatccc
      781 tgaagagaca ttccaacatc tgttcctctg tggcttttcg acctcagagg cctcagagcc
      841 tggtgtcatg tggcctggat atgcaggtaa tgctgtggag tcttcaaaaa gcccgtcctg
      901 tttggattac aaatttacag gaggatgaaa cagaggaaac ggaaggcccc cagacccctg
      961 gtcggctcct aaaccctgcg ctagcccact ctgtctctgt agcgtcgtgc ggcaatattt
     1021 ttagctgtgg tgcagaggat ggtaaggtgc gcatcttcag ggtgatggga gtcaaatgtg
     1081 agcgagaact gggatttaag ggtcacactt tgggggtatc ccaggtctgc tttctgcccg
     1141 agtccagtct gttgcttact ggagggaatg atgggaggat caggttgtgg gatgtgagcg
     1201 gtaagatgga gaagctgcag aagagccctg cgaggcacat ccacaggaag aaagcaaaga
     1261 gggcagcgtg ccccacgcag ggtggaaact ccagagcccc aggagccgag gatgaggggc
     1321 atgcaaagat tctgccaaag ctcgatattg aacacggaga aaaagtgaac tggcttttaa
     1381 gtacaaaaat taaagggaac aaaagcatat tagtggctga tcaaacgagt tgtgtgtctg
     1441 tgtatcccct aaatgagctt taggtccaat aaaatgcatt gcaaaaacca a
//
