LOCUS       NM_001370850            3223 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat domain 49 (Wdr49), mRNA.
ACCESSION   NM_001370850 XM_017319845
VERSION     NM_001370850.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3223)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC168120.3, AC124529.3 and AC147152.3.
            
            On Jun 6, 2019 this sequence version replaced XM_017319845.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849384
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AC168120.3         89547-89703         c
            158-306             AC168120.3         87755-87903         c
            307-540             AC124529.3         2642-2875
            541-705             AC124529.3         17664-17828
            706-821             AC124529.3         41281-41396
            822-952             AC124529.3         60211-60341
            953-1051            AC124529.3         61893-61991
            1052-1213           AC124529.3         64384-64545
            1214-1401           AC124529.3         66366-66553
            1402-1599           AC124529.3         67305-67502
            1600-1781           AC147152.3         180390-180571       c
            1782-1885           AC147152.3         158594-158697       c
            1886-2032           AC147152.3         154893-155039       c
            2033-3223           AC147152.3         130715-131905       c
FEATURES             Location/Qualifiers
     source          1..3223
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 33.75 cM"
     gene            1..3223
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /note="WD repeat domain 49"
                     /db_xref="GeneID:213248"
                     /db_xref="MGI:MGI:3645287"
     exon            1..157
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..2163
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /codon_start=1
                     /product="WD repeat-containing protein 49"
                     /protein_id="NP_001357779.1"
                     /db_xref="CCDS:CCDS89636.1"
                     /db_xref="GeneID:213248"
                     /db_xref="MGI:MGI:3645287"
                     /translation="MSGINTVVLAWREKSKKLLKMTSFNIAQGIHAFDYHSRLNLIAT
                     AGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQHQ
                     LSIQRITCSFPKSQDFRCLFQFDETHGRLFISFNNQLALLAIKNEASKRVKSHLKAVS
                     CVLYNSLLKQVISSDVGSTVSFWMIETGQKIKQFAGCHGNAEISTMALDANKTRLLTG
                     STDGTVKVWDFNGYCHYTLNVGQDGVVDISQILVLKKTILVVGWERALIVFRPQNFNQ
                     FFIQSEEWKGGVHHQDDILCAAFSPPQTLVTGSYDGEIVLWNNNTENAHHALHPGYQR
                     QLTSMVDVEAQKLNSRRSCESHGVADQATQAARNVKIDTEGNNAVMRLCFLEARKTKA
                     ATGGANLVSCGASGYVRFWDTFKKVLLAEFLAHAGVGSIIMSTDKLNQYLATGDSDGW
                     LKIWNIEEYCTNSTESKITQPPPLLRSSQPHEDRISSLEMCESCGRLLIISSSADCSV
                     CVTGLSSAPALIFGQASHWNIENHFSLPERDTNLIESKNQEERMKVNPLFSKEELCLD
                     STEHSLLTEEDEDNSTHLSTEEMNFSLKYKRRNSLKKKAYKPCYGEIIQTSTSTFGSL
                     CLRTLKELPEVKKPAFLLDPDKYFKEGPEEDVSQIPELPLLSETLKAVFDEKSLFPKE
                     LLYRERQDKSLCQETNGEMKIKQNKKQL"
     exon            158..306
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            307..540
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            541..705
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            706..821
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            822..952
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1051
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1213
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1401
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1599
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1781
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..1885
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2032
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..3223
                     /gene="Wdr49"
                     /gene_synonym="EG213248"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttctttag atgcattcat ttccagtaca atgagtggta taaatactgt ggtgttggca
       61 tggagagaga agtcaaaaaa actccttaaa atgacatctt tcaacattgc ccagggcatt
      121 cacgcttttg attaccactc tcggctcaat ttaattgcaa cggctggcat aaacaataaa
      181 gtttgccttt ggaatcccta tgtcctgtct aaaccagttg gtgttctatg gggtcattca
      241 gccagtgtca tagcagttca attctttgct gagagaaaac aacttttcag cttctccagg
      301 gataaagttt tgagactctg ggatattcag catcaactgt ccattcaaag gataacctgt
      361 tctttcccca aaagtcagga cttcaggtgt cttttccaat ttgatgaaac ccatggacga
      421 ctttttattt ccttcaataa tcagcttgct ttattggcca taaaaaatga agccagcaaa
      481 agggtgaaga gccatctaaa agcagtcagt tgtgttcttt acaattccct cctgaaacag
      541 gtaatcagct ctgatgtggg ttctactgtg tccttctgga tgatagaaac tgggcagaaa
      601 atcaaacagt ttgctggttg tcatggcaat gcagagatca gcaccatggc cttggatgca
      661 aataagacac ggcttttgac tggcagtaca gatggaactg taaaggtatg ggacttcaac
      721 ggatattgtc actatactct taatgttggg caagatggag ttgtggacat ttcacagatc
      781 ctggtactta agaagaccat cctggttgta ggctgggaga gagcacttat tgtatttcga
      841 cctcagaact ttaatcagtt tttcatccag tctgaagagt ggaaaggggg tgtccatcac
      901 caagatgaca tcttgtgtgc tgcattttca cccccacaaa ctcttgttac agggagctat
      961 gatggagaaa ttgttctgtg gaataacaac acagaaaatg ctcaccatgc gcttcaccct
     1021 ggctaccaga gacagctaac atccatggta gatgtagaag cccaaaagct caattccagg
     1081 agaagctgtg aaagtcatgg tgtggcagac caggccaccc aggctgcccg aaatgtaaag
     1141 attgacacag aaggtaataa tgctgttatg aggctttgct tccttgaagc aaggaaaacc
     1201 aaagcagcca caggaggggc taacctggtg tcatgtggag catctggtta tgtcaggttt
     1261 tgggatacat ttaagaaagt acttctggct gaatttttgg ctcatgctgg tgttggatcc
     1321 atcattatgt ctactgataa actgaatcaa taccttgcca ctggagattc tgatggatgg
     1381 ttgaaaatct ggaacataga ggagtattgt actaattcca ctgagagcaa aatcacccag
     1441 cctccacctt tgctcagatc atctcaacct catgaggacc ggataagttc cttggagatg
     1501 tgtgagtcct gtggtcgtct gctcatcatc tcctcctctg cagactgcag tgtctgtgtg
     1561 actggacttt ccagtgctcc tgccttgatc tttggtcagg caagccactg gaatattgaa
     1621 aaccactttt ctcttcctga acgggatact aatttaatag aaagtaagaa tcaagaggaa
     1681 agaatgaaag taaacccttt attttctaaa gaggagttgt gcttagactc aacagaacat
     1741 tctctactta ctgaggaaga tgaagacaac tcgacacacc tatcaacaga agaaatgaat
     1801 ttcagtctga aatataagag gagaaatagc cttaagaaaa aagcatataa accttgctat
     1861 ggtgaaatta tacaaacatc aaccagcacg tttgggtcct tatgccttag aaccctgaaa
     1921 gagctgcctg aagtgaagaa acctgcattt cttctagacc cagacaaata ctttaaggaa
     1981 gggccggaag aggatgtatc ccaaattcca gagcttcctc tgctctctga aactttgaaa
     2041 gctgtatttg atgagaaaag cctattcccc aaagaacttc tctatcgtga aagacaagac
     2101 aagtccctgt gtcaagaaac aaatggtgaa atgaagataa agcaaaacaa gaagcaattg
     2161 tgataaaata acaaacacac tactgttaca gagcactcta aaggatgctg agaagaaact
     2221 aggaccacac ttctgttact ttaagtgtga acttcaagaa acattgtctt cagactgcgt
     2281 gtttgttccg agttcattca tacttcccag tcttgtttaa tccaagaagg aacataaaaa
     2341 agattggtct aaagaagagt gatgtcaatt ggtatagtct atttcagaag aaagtaatta
     2401 cctagttgtc cttataattg tccctgtagt caaacactta taatttttaa taaaatcttt
     2461 atttaagcat gtaaaggact aaccaattga taaaatttca tttaaaatta tctatttctg
     2521 cgctcctttc ctttaaaatt tggttttcca caacaattct gatactgata attagatatt
     2581 gattacagca caatatctta ttctttttaa gaatacattt attttagctg tacaaattta
     2641 tggtgtataa tgttaaattt tggtatacac attaaaatgt gtattaattg ggattatgaa
     2701 catttacaaa ccattaaaca ttctcatgta tttttaatta acatgtgatc attgcacaaa
     2761 ttgatatgta tgtagtgggg ttaatatttc aacacatata tctaatatgt agtagttaag
     2821 ccagaataat tgctatttcc tagtaattat tttagagtta tgctcattat ttttatgcaa
     2881 acttttcttt atgtacatca tcttccaaga aaccaatatt attgagttgt tttttgttat
     2941 gtccttcatt aagaattaat tatgtcattt ctatgggttc agtttatttg tatatgctta
     3001 tattttaaag aggcctttaa aaatagttgg actttaaaac acttgcaata acactttagt
     3061 aaattactaa tatgtagtgg atgatttgat tcacaacaaa agcattcaat ctatttaaat
     3121 gtcatatgca ttcatttaaa atttgtctat tttaataatg aaatgtgaca tattgttcca
     3181 atatgagatt gtctagtaat aaaatatcgg tgttgggatt aca
//
