LOCUS       NM_001305675            4034 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WD repeat domain 44 (Wdr44), transcript variant 2,
            mRNA.
ACCESSION   NM_001305675 XM_006527701
VERSION     NM_001305675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
REFERENCE   2  (bases 1 to 4034)
  AUTHORS   Mammoto,A., Sasaki,T., Kim,Y. and Takai,Y.
  TITLE     Physical and functional interaction of rabphilin-11 with mammalian
            Sec13 protein. Implication in vesicle trafficking
  JOURNAL   J Biol Chem 275 (18), 13167-13170 (2000)
   PUBMED   10747849
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BB619844.1 and BC068151.1.
            
            On Mar 30, 2015 this sequence version replaced XM_006527701.2.
            
            Summary: This gene encodes a protein containing multiple WD
            repeats. The encoded protein may play a role in vesicle
            trafficking. Alternate splicing results in multiple transcript
            variants. [provided by RefSeq, Mar 2015].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049191.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                BB619844.1         2-67
            67-219              BC068151.1         1-153
            220-4034            BC068151.1         309-4123
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 17.36 cM"
     gene            1..4034
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /note="WD repeat domain 44"
                     /db_xref="GeneID:72404"
                     /db_xref="MGI:MGI:1919654"
     exon            1..219
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            220..334
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     CDS             258..3005
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /note="rabphilin-11; rab11-binding protein"
                     /codon_start=1
                     /product="WD repeat-containing protein 44"
                     /protein_id="NP_001292604.1"
                     /db_xref="CCDS:CCDS40892.1"
                     /db_xref="GeneID:72404"
                     /db_xref="MGI:MGI:1919654"
                     /translation="MASESDTEEFYDAPEDVHLGTGYPVGSPGKVGLLSFKEAENTAN
                     QAGNESPVQELRQDVSKKIIESIIEESQKVLQLEDDSLDSKGKGLSDEATAGPSVAGT
                     EFSNIPGLLAIEHELQQDSEKAESQNVAEESELETQKCFPSDETCEKSEKTVDETDNL
                     TEVSSGEQLDASGLEAETLNKEALEVKEGDVLDPASLDTLSTTDFAAVEEVAPAKPPR
                     HLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPAPPPRKKKSELEFEALKTPDL
                     DVPKENITSDSLLTTNMASENTVRDSLPSLDLASATSGDKIVTAQENGKAPDVQTVAG
                     EVMGPQRPRSNSGRELTDEEILASVMIKNLDTGEEIPLSLAEEKLPTGINPLTLHIMR
                     RTKEYVSNDATQSDDEEKLQSQQTDTDGGRLKQKTTQLKKFLGKSVKRAKHLAEEYGE
                     RAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDL
                     SGEHMGAVWTMKFSHCGRLLASAGQDNIVRIWALKNAFDYFNNMRMKYNTEGRVSPSP
                     SQESLSSSKSDTDMGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFLL
                     SSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDK
                     KVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGR
                     NKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSH
                     DFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSL
                     MLSLDVQSEKLEGIDKYEDAEVLDSTSTGIVKTDNTEVLLSADFTGAIKVFINKRKTV
                     S"
     exon            335..368
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            369..443
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            444..1089
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1220
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1316
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1453
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1537
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1644
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1796
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1935
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2000
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2001..2114
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2237
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2429
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2430..2531
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2532..2647
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2648..2775
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2910
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     exon            2911..4024
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3943..3948
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /note="hexamer: ATTAAA"
     polyA_site      3978
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
     regulatory      3996..4001
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /note="hexamer: ATTAAA"
     polyA_site      4024
                     /gene="Wdr44"
                     /gene_synonym="2610034K17Rik; RAB11BP; RPH11"
                     /note="major polyA site"
ORIGIN      
        1 aggtgcgcgt cggtattttg cgggctagta gctttccctg caactgtaat tgccgctgcg
       61 ggagaaattg gagctgctgt cgctggcacg cccgctgcct gctctccggg acggagaagc
      121 gccacagcct cttctctagc gctctccata cacctagcgc ccgggtcgcc ggccactgtc
      181 ccagacccac tgcagccacc tcaggcagtc gctctgcagg cggagccggc cccctcaccc
      241 gcgggtgtgt cctataaatg gcgtcggaaa gcgacaccga agaattctat gatgcccctg
      301 aagatgtgca cctggggacc ggctatcctg tagggtctcc aggaaaagtt ggacttttat
      361 catttaagga agccgagaat acagcaaacc aagctggaaa tgagtcccct gtacaagaat
      421 tgagacaaga tgtatctaaa aagataattg aaagtattat tgaggaaagt cagaaagtac
      481 tacaattgga agatgactct ttggactcca aaggaaaagg actttctgat gaggctactg
      541 caggtccttc tgtggctggg acagagttta gtaacatacc tggactatta gccatagagc
      601 atgaactaca acaagattcc gaaaaggcag aaagtcagaa tgtagctgaa gaaagtgaac
      661 tagaaacaca aaaatgtttt ccttctgatg agacctgtga gaaaagtgag aagacagtag
      721 atgagactga taatttaact gaagtaagtt caggtgagca gcttgatgct tctggactag
      781 aagctgaaac actgaacaag gaagcattgg aagtcaaaga aggtgatgtt ctagatcctg
      841 cctccttgga cactttatct actacagatt ttgctgctgt ggaagaagtg gctcctgcca
      901 aacccccaag gcaccttact ccagaacctg atatagtagc cagtacaaag aagcctgttc
      961 ctgcgcgccc acccccacca actaatttcc cgcctcctag acccccacct ccatctcgac
     1021 ctgcaccacc accaagaaaa aagaaaagcg aactggagtt tgaggctctt aaaacacctg
     1081 atctggatgt acccaaagaa aatattacat ctgattctct gctaactaca aatatggctt
     1141 cagagaatac agttagagat tccctgcctt ccctcgattt agcaagtgct accagtggag
     1201 ataaaatagt aactgcccag gaaaatggaa aagcacctga tgtgcagaca gtagcaggtg
     1261 aagtgatggg ccctcagaga cctagatcca actctgggag agagcttact gatgaggaaa
     1321 ttttagccag tgtcatgatt aagaacctgg atactggaga agaaatacct ttaagtcttg
     1381 ctgaagagaa gttgccaaca ggtattaatc ctctcactct gcacatcatg agaaggacaa
     1441 aggaatatgt aagcaatgat gccacacagt cagatgatga agaaaagtta cagtcacaac
     1501 aaacagatac tgatggtgga aggttaaaac agaaaacgac tcaactaaag aaattccttg
     1561 gaaaatcagt gaagagagca aagcatcttg ctgaggaata tggtgaacgt gctataaata
     1621 aagttaaaag cgtaagagat gaagtgtttc atactgatca agatgaccct tcatcaagtg
     1681 acgatgaagg aatgccatat acaagaccag taaaattcaa ggcagcacat ggtttcaaag
     1741 gaccttatga ttttgatcag atcaaagtgg tgcaagatct tagtggtgaa cacatgggag
     1801 ctgtttggac catgaagttt tctcactgtg gccgactgct tgcttcagct ggacaagaca
     1861 acatagtgag aatatgggct ttaaaaaatg cttttgacta tttcaacaat atgcgaatga
     1921 aatacaatac tgaaggacgc gtgtcacctt caccatctca ggaaagtcta agttcatcaa
     1981 aatctgacac agacatgggg gtatgtagcg gaactgacga agacccagat gacaaaaatg
     2041 caccgtttcg gcagcgacca ttttgcaaat ataaaggaca tactgctgat ctccttgatc
     2101 tttcatggtc taaaaactac tttctgctct cttcttctat ggataaaaca gtcaggttat
     2161 ggcacatttc tagaagagaa tgcctttgct gttttcaaca tatagatttt gtcactgcca
     2221 tcgctttcca tccaagagat gacagatatt ttctcagtgg atcattggat ggaaagctcc
     2281 gcctatggaa catacctgac aaaaaggtgg ctttatggaa tgaagtagat ggtcagacaa
     2341 agttgatcac agctgccaat ttttgtcaga atggcaaata tgcagtaatt gggacatatg
     2401 atggtagatg tattttctat gatacagagc atttgaaata ccatacacaa atacatgtac
     2461 gatctactag aggacgcaac aaggttggaa gaaaaattac tggcattgaa cctttacctg
     2521 gagaaaataa gatactggta acctcaaatg actccagaat cagactgtat gatctgagag
     2581 acctatcact gtccatgaag tataagggtt atgtcaatag cagcagccag atcaaagcaa
     2641 gtttcagtca tgactttact tacctcgtta gcggttcaga agataaatat gtttatatct
     2701 ggagtacgta ccatgaccta agcaagttta cttcagtcag gagagatcgt aatgacttct
     2761 gggaaggtat taaagcacat aatgcagttg ttacgtcagc catctttgct ccaaacccaa
     2821 gtttgatgct atccttggat gtgcaatctg aaaaattaga agggattgat aaatatgaag
     2881 atgctgaagt tttggatagc acatctactg gtattgtgaa gacagataac acagaagttc
     2941 ttctttctgc tgattttact ggagcaatca aagtgtttat taacaaaagg aaaactgtat
     3001 cttaatttga aattatattt aaaataaaca tatcagtaag tttctatatg tatcataaat
     3061 gagaaaagta ttatagtgtt tcaggctaac atcccttttt agcttttatt gaaagttgtt
     3121 caaatataat atatattttt tgagaggcag tgttagtgat ctaggaactc ctagactgat
     3181 agactagaaa agaatgtggt tagattaaca ttgccaagca tagagtttat gttttgttat
     3241 gtttatgttt tgttatataa ttataaacat gcacaggttt ctgcatgaaa agatattaat
     3301 atattaatca catgtgcgtg ccttttggtt acatgcacta aatctaacaa agttaaatta
     3361 ttttggtggc tcttttggcc tcctactggg tgaggtggtc ttgtttctag ttctaaaaaa
     3421 tttttttgca caaaatttcg tttttaagaa atgtatcttt tgactgaatt attgttttga
     3481 aatgttatat aggttttcaa taggtcaata accatgtgta aatggttttt tataaatttc
     3541 tcaatttggg gacaagattt tttttgtgat ctaaattgtg gacttattct ttactttgta
     3601 agtgtatata tatataattt ttttctttgc cacactggag cacaatgttt ctatgtaaag
     3661 aattcttttc tttatccatg agcaccaggc tttgctcact taaaaataag ccacattaag
     3721 gagtgagtct tcttttttac aataatgtaa aaatgaactg tttacatttt tttaaagcat
     3781 tgtagttttt aaaaaaaaat aagctgtttt gttttgtgtt gttgaatttg aaaggctttg
     3841 taaataccaa tataatgtac caatgaaata acatctggga caatagaacc ctggtaatgt
     3901 tgttgatggt ttgcatatgt ttctgaaact gaagtatgta tcattaaagt tggtcatcaa
     3961 cacttgttaa aggtgaaata ttttgagatg acattattaa atcaaaagat gcaagaaaaa
     4021 taaaaaaaaa aaaa
//
