LOCUS       NM_145514               7043 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus WD repeat domain 26 (Wdr26), transcript variant 1,
            mRNA.
ACCESSION   NM_145514 XM_890196 XM_915888 XM_923994 XM_923998 XM_924002
            XM_924005 XM_924010 XM_924013
VERSION     NM_145514.6
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7043)
  AUTHORS   Sun,F., Cheng,Y., Riordan,J.D., Dupuy,A., Dubois,W., Pisano,M.,
            Dong,J., Mock,B., Zhan,F., Hari,P. and Janz,S.
  TITLE     WDR26 and MTF2 are therapeutic targets in multiple myeloma
  JOURNAL   J Hematol Oncol 14 (1), 203 (2021)
   PUBMED   34876184
  REMARK    GeneRIF: WDR26 and MTF2 are therapeutic targets in multiple
            myeloma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7043)
  AUTHORS   Sun,Z., Tang,X., Lin,F. and Chen,S.
  TITLE     The WD40 repeat protein WDR26 binds Gbetagamma and promotes
            Gbetagamma-dependent signal transduction and leukocyte migration
  JOURNAL   J Biol Chem 286 (51), 43902-43912 (2011)
   PUBMED   22065575
  REMARK    GeneRIF: WDR26 is a novel Gbetagamma-binding protein that is
            required for the efficacy of Gbetagamma signaling and leukocyte
            migration
REFERENCE   3  (bases 1 to 7043)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113084.12.
            
            On Apr 1, 2022 this sequence version replaced NM_145514.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13948564.5540914.1, AK075743.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-903               AC113084.12        81903-82805         c
            904-1003            AC113084.12        80040-80139         c
            1004-1108           AC113084.12        79830-79934         c
            1109-1245           AC113084.12        73851-73987         c
            1246-1343           AC113084.12        69674-69771         c
            1344-1500           AC113084.12        68402-68558         c
            1501-1639           AC113084.12        62588-62726         c
            1640-1780           AC113084.12        58433-58573         c
            1781-1900           AC113084.12        56775-56894         c
            1901-2046           AC113084.12        55078-55223         c
            2047-2125           AC113084.12        54554-54632         c
            2126-2255           AC113084.12        53596-53725         c
            2256-2441           AC113084.12        52131-52316         c
            2442-7043           AC113084.12        44057-48658         c
FEATURES             Location/Qualifiers
     source          1..7043
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 84.53 cM"
     gene            1..7043
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="WD repeat domain 26"
                     /db_xref="GeneID:226757"
                     /db_xref="MGI:MGI:1923825"
     exon            1..903
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     CDS             542..2467
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="isoform 1 is encoded by transcript variant 1; WD
                     repeat-containing protein 26"
                     /codon_start=1
                     /product="WD repeat-containing protein 26 isoform 1"
                     /protein_id="NP_663489.4"
                     /db_xref="CCDS:CCDS15583.2"
                     /db_xref="GeneID:226757"
                     /db_xref="MGI:MGI:1923825"
                     /translation="MQANGAGGGGGGGGGGQGQTPELACLSAQNGESSPSATSAGDLA
                     HANGLLPAAPSAAGNNSNSLSVNNGVPGGAAAASATAAAAQATPELGSSLKKKKRLSQ
                     SDEDVIRLIGQHLNGLGLNQTVDLLMQESGCRLEHPSATKFRNHVMEGDWDKAENDLN
                     ELKPLVHSPHAIVVRGALEISQTLLGIIVRMKFLLLQQKYLEYLEDGKVLEALQVLRC
                     ELTPLKYNTERIHVLSGYLMCSHAEDLRAKAEWEGKGTASRSKLLDKLQTYLPPSVML
                     PPRRLQTLLRQAVELQRDRCLYHNTKLDNNLDSVSLLIDHVCSRRQFPCYTQQILTEH
                     CNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPD
                     DSYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQF
                     YQCDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQRVRGYNFEDLTDRNIVQEDHP
                     IMSFTISKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFI
                     ASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPA
                     PFIDHQNIEEECSSMDS"
     exon            904..1003
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1108
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1245
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1343
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1500
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1639
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1780
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1900
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            1901..2046
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            2047..2125
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2255
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2441
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     exon            2442..7043
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4374..4379
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="hexamer: AATAAA"
     polyA_site      4399
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="major polyA site"
     regulatory      5173..5178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="hexamer: ATTAAA"
     polyA_site      5195
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
     regulatory      7022..7027
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="hexamer: AATAAA"
     polyA_site      7043
                     /gene="Wdr26"
                     /gene_synonym="1600024A01Rik; Gid7"
                     /note="major polyA site"
ORIGIN      
        1 agacagcagc tgggggaaga atcaacacac cagggagcgg agcggcgcgg acccagcacc
       61 gaggcggccg ctgcctccgc cgccgcctcc gccgccgccg tccgggctcc cagcttcggg
      121 cccgcgcccc ccccagtgcc cgcgagcccc cgggccgcgc cgcgagcgcc tccggagggg
      181 gggggaaggg cccggtcctc cttctccccc tcctcccgcc ccgccgaccc ccgccgcgcc
      241 ccgccggcct cccaccacgg cctctctcgg cgaggaaact ctggcctccg cttcctcctc
      301 ctccgactcg gacgccggcg gagcctcccc gcccccgcga aagaagcccc gagcctcggc
      361 ggcggaggga gcaggagagc ccggggcctc ggcgggccga gcaggcctcc cccccccgcc
      421 ctcgccctcg ccggccgcct cctcctcctc ctcctccgtg gtggtggtgg tgggactgcc
      481 tccggccgcc cccgccgccc cgcagcggag cagcggccac agcctggtca gcggcggcac
      541 catgcaggcc aacggggcgg gaggaggcgg cggcgggggc ggcgggggcc agggccagac
      601 cccggagctc gcctgcctgt cggcgcagaa cggggagtcg tccccttcgg cgacgtccgc
      661 gggggacctg gcccacgcca acgggctcct gcctgccgcc ccctccgccg ctggcaacaa
      721 tagcaacagc ctgagtgtca ataacggggt tcccggcggg gccgccgcgg cctccgccac
      781 cgccgccgcc gcccaggcca cccccgagct gggcagcagc ctcaagaaga agaagcggct
      841 ctcgcagtcc gatgaggatg tcattaggct cataggacag cacctcaatg gcctagggct
      901 caaccagact gttgatctcc tcatgcaaga gtcaggatgt cgtttagagc atccttctgc
      961 taccaaattc cgaaatcatg tcatggaagg agactgggat aaggcagaga atgacctgaa
     1021 tgagctaaag cctttagtgc attctcctca cgctattgtg gtaagaggcg cacttgaaat
     1081 ctctcaaacg ttgttgggaa taattgtgag gatgaagttt ctgctgctgc agcagaagta
     1141 cctggaatac ctggaggacg gcaaggtcct ggaggcactt caagttctac gctgcgaact
     1201 gacgccgttg aaatacaaca ccgagcgcat ccatgtcctt agtgggtatc tgatgtgcag
     1261 ccatgccgaa gacctacggg caaaagctga atgggaaggc aagggcacag cgtcccggtc
     1321 caaactgctg gacaagcttc agacctattt accaccatca gtgatgcttc ccccacggcg
     1381 tttacagact ctcctgcggc aggcggtgga actacaaagg gatcggtgcc tatatcacaa
     1441 taccaaactt gacaataatc tagattctgt gtctctactt atagatcatg tttgtagtag
     1501 gaggcagttt ccctgttaca ctcaacagat acttacagag cattgtaatg aagtgtggtt
     1561 ctgtaaattt tctaatgatg gcactaaact agcaacagga tcaaaggata ccacagttat
     1621 catatggcaa gttgatccgg atacgcacct gttaaaactg cttaaaacgt tagaaggaca
     1681 tgcgtatggt gtctcttata tagcatggag tccagatgac agctatcttg ttgcttgtgg
     1741 tccagatgac tgctctgagc tttggctttg gaatgtacag acgggagaat taagaacaaa
     1801 aatgagccaa tctcatgaag acagtttgac cagtgtggcc tggaatccag atgggaaacg
     1861 ctttgtgacg ggaggtcagc gtggtcagtt ctaccagtgt gacctggacg gaaatcttct
     1921 ggactcctgg gaaggagtgc gagtacagtg cctgtggtgc ttgagtgacg ggaagactgt
     1981 gctggcttcc gacacgcacc agagagtccg gggctacaac tttgaggacc tgacagatag
     2041 aaacatagta caggaagatc atcctattat gtcatttact atttccaaaa atggccgatt
     2101 agctttgtta aatgtagcaa ctcagggagt tcatttatgg gacttgcaag acagagtttt
     2161 agtaaggaaa tatcaaggtg ttacccaagg gttttataca atccactcgt gttttggagg
     2221 ccataatgaa gacttcattg ctagtggcag cgaagatcac aaggtttaca tctggcacaa
     2281 acgtagtgaa ctgccaattg cggagctcac agggcacacg cgcacagtaa attgtgttag
     2341 ctggaaccca cagattccat ccatgatggc cagtgcctca gacgatggca ctgttagaat
     2401 atggggacca gcacctttca tagaccacca gaatattgaa gaggaatgca gtagcatgga
     2461 tagttgatgg caaatttgga gcagacgact tctgtttaac ttaaaattag tcgtatttta
     2521 atggcttggg atttggtgca aacaaacatg attgatagct ggacagacat gctcgtcatg
     2581 aaaaaaaaaa aaaaagaacc attttgaagc ccgattgggg ccaaacattt acaccttgct
     2641 tcctagtaac cagttgatga agcgcgtcta gaacgttgtt ggacaccatg ttgaattatt
     2701 ccccatcggt tgtgaagaac tgtgctacat tcaggcttac ccattgaact cagtatatat
     2761 attttttccc tcctgccttt tgtctggtgg gacaccattc ttgttgctct tctgtgtaat
     2821 gaagttcaaa tgcttgtttg gaaactttat ttaacagttt agaaggcttg ataggaagag
     2881 gtcattagtc tgaagagtat acattggaca ggaaagaatt tcctttcgtt tctccaaatc
     2941 tttccgcctt atttagcgtg agatctttgc agcttggttc atggattcta gccttgcccg
     3001 ttgcgcagta tatgctgatc agatgataaa ccagtgaact atgtcaaaag cactctcaat
     3061 attacatttg acaaaaagtt ttgtactttt cacatagttg ttgccccgta aaagggttaa
     3121 cagcacaatt ttttaaaaat aaattaagaa gtatttatag gattaaagtg acttcatttg
     3181 tatacatttg gaatctaaac cagcttaaaa acagtgtcct ctgtgactga gatatgcagt
     3241 gtaactgatg ctcttctgga gtgccacgtg agacatggca tggtcagaaa cagtgttcag
     3301 aaggacacgg cacaggaaag ccagagagat actttcccct ttttatttta ttcctgaagg
     3361 gacatcagta cctgatactg aagaaattca agattcaaaa ggaaaatttt ataaataaac
     3421 cagtacagaa gatcagcatc agtctaggtt ttcaagaaag cttgttccaa gttctctgaa
     3481 cttgagggaa tcgttttgat gtgatctagc agaagtagac atcagaagat agacctactt
     3541 tgggaattta tagtgtagtt aaatcttaga ggaagtcagc aggctacaaa catttatgta
     3601 aactggaatt aaagcctgag tcatttctcc taattgccct taatgtccaa catataggga
     3661 cactcattta aagaagattc cttctcagct tctcagatgt tgccataatg aacctcattc
     3721 aaactggtgc tgtggacagt ctttccctct ccctcccctt ttagtttacg ggaatgtttc
     3781 ctttatggaa aaaaagtgac ttgtcatttt gaagacccta tatctaacat aagcctgatt
     3841 gatgttcatg gtgttttcaa ctccataatt gctgggtcta accagtctcc cttgaaatcc
     3901 atgttttcca ataggagata accagggtga ccacagctct tggaaggaaa agtggaatta
     3961 actccaatgt atcctgatga acaacaacaa caaaaatctg gtacaacttg cccttgaggc
     4021 caagccaagt ccatagcatt caccatgatc atatgcccct cgggatcctg agagaagaga
     4081 gaggcttgta ctgaggggtc ttcccattgt gggggtcgca gggagggaaa agccaggaag
     4141 gcagtggtca ttctcccaaa gtccacccat cgtaaggagg tgacagatcg gagtcagcag
     4201 attagtaatt caaatgggta atggaaaaga ttcctttaag cttcattttt cagagaccat
     4261 cactttagaa aatcagagaa atcctgtttt gatacttctt agttaaaata atatgttacc
     4321 gtttatctgg tacttcattt tcttgactaa aattactttt cactttaagc ttgaataaaa
     4381 attttcattc ataactgtat ataattaagt ggcaactcct ctttacctca gtgcagttaa
     4441 gaccatcttt tgattgatat accctgaagc cattaatcca tacacctcag tctacagtaa
     4501 caatccctaa caccatgtgg gcacagaact ccacagctgt ttacagatgt ggttacagtg
     4561 taccacgtgg catgtgcatg atgctccctg agggctgtac ccatcagggc agttttgtat
     4621 ccagctgcac ctagacccgc ctgttcactg cttctgaagt acatttaaaa acactgggag
     4681 gtaagagcgt gccccgaagg tgagggccat gaccagaaca taactcctgt tagagtggag
     4741 ttacaactat gcaaaggtgt tgatagtagc taggtgagtt cggtttccaa gtctgtctta
     4801 actggccgct ccctctctag actggtactt gactgtgcca atttgctgta agcatctgtt
     4861 tcgtatattt gccatgaagt gagtgtggta gaaaggtgaa gaaagctagg gtttatggtg
     4921 gaagaacctg gtgacaggat tacgtgaaaa tctctgacat tgtgataaac tcgataaagg
     4981 cttaagagaa ttctgtcaag cctgccacaa gatgctaacc aatgtataaa ctgaaaagta
     5041 ccaatacttt ttgcacatag atcaaaatag tggagaattt tggctccaaa aatcaggtta
     5101 gtaggctcaa ttccatgtgc ttaaaatgtt tctgttgtta atgcatcgat taagggctag
     5161 agtaagaatg gaattaaatg tctttttcct ctaaattaac tggttattag tggtaaagtg
     5221 ttggatttgg ggggggggtc actgaggttg gtttgtgggt ggtgatcaaa agaattagca
     5281 tgggagttag gggagatgac gaagcttcac acttggggtt tgaattccat tagtattcgt
     5341 gccagctgtg tggcattgct cttcctggcc agttaaatgt cctggtaacc caggtaagta
     5401 gtaaaaacag ggcattttac ttgcaaatgt ccccttaaat tggctcattt tattgggtag
     5461 gagaacaaaa actagaattc tccgactata agtaattaag tggacctgct aggcaaacag
     5521 aagcagtaat tccgcaagag cagttgatga ggagcagtct gccttaaggg gcgtcctgtg
     5581 gcattaatag aaaatccttt cccacccctc cccatcttga aattttcttt tctaggatgt
     5641 tggttcctgc aaacaagaac tgaccctctg cctcccttgg gtacacgtct tgcacatctc
     5701 ttgaacgggg gcaatgccta tgtcgtttac tttacagcag aagaatggga ggagaggaga
     5761 tacattgtct tagttgttcc cattttaaaa aaatatattt ttacttaatt ttactttgat
     5821 gtctcattta gacatcacca actctccctt tgtgttgctg gccaaagcat tcccaccatt
     5881 tccaaaacca tacctgattt cacataaact gctaacttaa agggtgaatt tgcatttaca
     5941 cttagacact ttctaaaaac agggtgaaat taacctaaac tttgcagtgt tgagttattg
     6001 ttatagtcgc tgccctagag ttgcaaaaac aagctgtaaa agcccatccc ctatctactt
     6061 aatccagatt gcctggattt aatgaagtta aaagagtgtg tgtgtgtgtg ttttgtgtgt
     6121 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgttt gagtgtttga gaaagaactt
     6181 gattcctaaa atattctaga aacaactttt aggttgtcat ttttactgaa tgtcttgtgc
     6241 acatgtaaag taccctctct tgagtttaag gcttggttaa tacttgtcta tttttataaa
     6301 acttaaaact gtgtcccatc tttaacttag acatttacat tatcaggatc aacatgctag
     6361 aattaaataa catttgtagg ctcagtgagg gtaaatgtta ttggcagaga gagagagaga
     6421 gagagagaga gagagagaga gagtgtatgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     6481 gtgtgtgtgt gtgtgtgttt tcctgaggga gatcccgaaa gcatgtatgt gcttataaac
     6541 caagctgtag agatcatgta aagacgctgg gtgttgctct ggaggtttct gagctatgga
     6601 aagggatagg gcattgtggt gtgatgtagc taacacagag ctcttggtat ggagtaacag
     6661 ttaactatgg actgatgttt ccagacgatt gtgttcttaa tggggtttgc ttttttattt
     6721 gcctctcaga ttatgtttag tagtttaaat ttctttgttt tattatttca ttaaagtata
     6781 aaaacttcag gtctcatatt tattttcact tgttctacta attatttaca agacactttt
     6841 tggttgacat ttattttata aatgtgtggt atattaaatg tctttaattt tttttgtttt
     6901 attgaaatta cagtaacttt gatttgcttt actgggattt ttaaatttta ttttaattcc
     6961 actttttcca tgtcagtgca cagcacttgc ccagtccttt gtatcccctt tctgtcgatt
     7021 caataaacag aatgagtaat taa
//
