LOCUS       NM_177602               2657 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WD repeat domain 25 (Wdr25), mRNA.
ACCESSION   NM_177602 XM_001474974 XM_001476637
VERSION     NM_177602.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2657)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122811.4 and AC140111.3.
            
            On or before Apr 19, 2009 this sequence version replaced
            XM_001476637.1, XM_001474974.1, NM_177602.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849381,
                              SAMN00849382 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                AC122811.4         77696-77737
            43-859              AC122811.4         81333-82149
            860-1007            AC122811.4         164115-164262
            1008-1138           AC140111.3         70914-71044
            1139-1309           AC140111.3         103070-103240
            1310-1450           AC140111.3         104517-104657
            1451-2657           AC140111.3         105353-106559
FEATURES             Location/Qualifiers
     source          1..2657
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 59.7 cM"
     gene            1..2657
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /note="WD repeat domain 25"
                     /db_xref="GeneID:212198"
                     /db_xref="MGI:MGI:3045255"
     exon            1..42
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            43..859
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1672
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /codon_start=1
                     /product="WD repeat-containing protein 25"
                     /protein_id="NP_808270.2"
                     /db_xref="CCDS:CCDS49172.1"
                     /db_xref="GeneID:212198"
                     /db_xref="MGI:MGI:3045255"
                     /translation="MASLVAYDDSDSETEADPARSGDAAGQISDASGMSRPSGMGFAS
                     STVGVTKEGAQHTGNSPNEDPGMQRLPLARLWRSDPGSCPSQRLQWPSKEPDTTFPPS
                     EPPRPSLWMSRAPVGHVPLAAACLKPLKPAWDVLKPSHDQSTFESTAGNASSSQRKRG
                     EDCVLPYIPKRLRQLQALNPEAGGGKDGEPPGPPAGCAPAPLCVAPTVSEFIQPYLNS
                     QYRETTVPKKVLFHLRGHRGPVNSIQWCPVFCKSHMLLSASMDKTFKVWNAVDSGHCL
                     QTYSVHSEAVRAARWSPCGRRILSGGFDFALHLTDLETGTQVFSGQSDFRVTTLKFHP
                     KDHNVFLCGGFSSEIKAWDMRTGKVVKGYKATIQQTLDILFLQEGSEFLSSTDASTRD
                     SADRTIIAWDFRTAAKISNQIFHERYTCPSLALHPREPVFLAQTNGNYLALFSSVWPY
                     RMSRRRRYEGHKVEGYAVGCECSPCGDLLVTGSADGRVLMFSFRTASRACTLQGHTQA
                     CLGTTYHPVLPSVLGTCSWGGDIKIWH"
     exon            860..1007
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1138
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1309
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1450
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..2657
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2637..2642
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2657
                     /gene="Wdr25"
                     /gene_synonym="B930090D16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagtgctggc cggaccgttg taggggtgga ccaagagctt ccgaagtcac ctttgtgtga
       61 ctgtatggcc tcgctggtgg catatgatga ttctgactcc gagaccgagg ctgaccctgc
      121 cagaagtggg gacgctgcag gtcagataag tgacgcctct ggtatgagca ggccgtctgg
      181 gatggggttt gcatctagca cagtgggcgt gaccaaagag ggggcacagc acacagggaa
      241 ctctcctaat gaagacccag ggatgcaacg tctgccgctg gctcggctct ggagaagtga
      301 ccctgggtct tgtcccagcc agaggctaca gtggccctca aaggaacctg ataccacttt
      361 ccctcccagt gagcctcctc gtccttctct gtggatgagc cgggctccag tcggccacgt
      421 gcccctagca gctgcctgtc ttaagccact aaaacctgcc tgggacgtcc tcaaaccttc
      481 tcatgatcaa agcacatttg aaagcacagc tggaaatgcc agctcttctc agaggaaaag
      541 gggtgaggac tgtgtgcttc cctatatccc caagaggcta aggcagctgc aagcgctgaa
      601 tccagaagca ggtgggggca aagatggaga gcccccggga cctcctgcag ggtgtgcccc
      661 ggccccactc tgtgtggctc ccacagtgtc tgagttcatc cagccatatt tgaacagtca
      721 gtacagagag actacggtcc ccaagaaagt gcttttccac cttcgaggcc acaggggccc
      781 ggtcaacagc attcagtggt gtccagtctt ttgcaagagc cacatgcttc tctctgcttc
      841 catggacaaa accttcaagg tgtggaatgc tgtggactcg ggacactgcc tgcagaccta
      901 ctctgtgcac agtgaggcag taagggctgc acggtggtct ccctgtggcc ggcgcatcct
      961 cagtggtggc ttcgactttg ccctgcacct aacagacctt gaaacaggaa cccaagtgtt
     1021 tagtggtcag agtgacttca gagtcaccac cttgaaattt catccaaaag accacaacgt
     1081 ctttttatgt ggcggcttca gctctgaaat caaagcttgg gacatgagga ctggcaaggt
     1141 ggtgaaaggc tacaaggcca ccatccagca gaccctggac attctcttcc tccaggaggg
     1201 ctccgagttt cttagcagta cggacgcatc cacccgggac tctgctgacc gaaccattat
     1261 cgcctgggat ttccggaccg ctgccaagat ctccaaccag atcttccatg agaggtacac
     1321 ctgtcccagc ctcgccttgc atccaaggga gcctgtgttc cttgcacaaa ccaatggcaa
     1381 ctacctggct ctcttttcct ctgtgtggcc ctatcggatg agcagacgga gacgctacga
     1441 aggtcacaag gtggaaggct acgcggtggg ctgtgagtgt tccccatgtg gtgacctgct
     1501 ggtgacaggc agcgctgatg gccgggtttt gatgttcagt ttccgcacgg ccagccgagc
     1561 gtgcacacta caagggcaca cgcaggcctg ccttggcacc acctaccatc ctgtgctgcc
     1621 ttctgtcctc gggacctgct cctggggagg agacatcaag atctggcact aactggcaac
     1681 tgagaccctg cccctgggta ggcggccgga ggttaggctg ctcccgagag ctgctgggct
     1741 tcagtgactc ggctatagca tgggggtgag aagccgtctc ggcgcaagcg tgtgttagta
     1801 aaggtgtttg ccgagtgact ggtgggtgac acgcaatcag taagcgtgtg ctctgtatgg
     1861 tttggttggt tgattggtct tttacttgtt tgtttgtttt gtttctggtt tttcaagaca
     1921 gggtttctct gtgtagccct ggtggtcctg gaactcaggc tggccttgaa ctcagggacc
     1981 cacctgcctc tgcctcctga gtgctgagat gaaaggtgtg tgccaccacg cctggtgtgg
     2041 tttttcttaa tgtgattttg gcaatgaaca catattagca gtgtcttcct gccttcttac
     2101 tgcagatagg ggagcttgag atgggactgt cacctgctgg tccttcggac agtgaggctc
     2161 tggggcttgt gactgcccag gagctcagtg cacctcagcg ccccccacca ccaccccact
     2221 ataagacacc aacaactgtg tttcttccta cccacctctg gtcctctaac ttgctgcctg
     2281 cccactgcca ggtgggtggt ctgtggtggg caaagctatg catctgtcct gaaggagtgc
     2341 gaggagaagc agggactcag aagcacatag aaggaagtgt ggcatgtagg gagtggaact
     2401 gttggaaagg atgacgagga ttaggaggcg tggccttgtg ggaggaagtg tgtcactggg
     2461 ggtgggcttt gaggtttcag aagctcacac caggtccagt ggatctctct ccaccttcag
     2521 atgaggatgt agaactctta gctactgctc cagcgccatg cccgcactct gccatgcttc
     2581 ctcccaccat gatgataatc tgaatgatga acctctgaaa ctgtaaaccc gcttcaatta
     2641 aatgcttttt aaaataa
//
