LOCUS       NM_153391               4403 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus WD repeat domain 19 (Wdr19), transcript variant 2,
            mRNA.
ACCESSION   NM_153391
VERSION     NM_153391.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4403)
  AUTHORS   Yu,S.S., Wang,E., Chiang,C.Y., Cheng,P.H., Yeh,Y.S., Wu,Y.Y.,
            Chiou,Y.Y. and Jiang,S.T.
  TITLE     Large deletion of Wdr19 in developing renal tubules disrupts
            primary ciliogenesis, leading to polycystic kidney disease in mice
  JOURNAL   J Pathol 257 (1), 5-16 (2022)
   PUBMED   35007346
  REMARK    GeneRIF: Large deletion of Wdr19 in developing renal tubules
            disrupts primary ciliogenesis, leading to polycystic kidney disease
            in mice.
REFERENCE   2  (bases 1 to 4403)
  AUTHORS   Lee,H. and Ko,H.W.
  TITLE     Cell cycle-related kinase is a crucial regulator for ciliogenesis
            and Hedgehog signaling in embryonic mouse lung development
  JOURNAL   BMB Rep 53 (7), 367-372 (2020)
   PUBMED   32317081
REFERENCE   3  (bases 1 to 4403)
  AUTHORS   Fu,W., Wang,L., Kim,S., Li,J. and Dynlacht,B.D.
  TITLE     Role for the IFT-A Complex in Selective Transport to the Primary
            Cilium
  JOURNAL   Cell Rep 17 (6), 1505-1517 (2016)
   PUBMED   27806291
REFERENCE   4  (bases 1 to 4403)
  AUTHORS   Wainwright,E.N., Svingen,T., Ng,E.T., Wicking,C. and Koopman,P.
  TITLE     Primary cilia function regulates the length of the embryonic trunk
            axis and urogenital field in mice
  JOURNAL   Dev Biol 395 (2), 342-354 (2014)
   PUBMED   25224227
  REMARK    GeneRIF: Mutations in Ift144, encoding a component of the
            trafficking machinery of primary cilia assembly, result in a range
            of embryo patterning defects, affecting the limbs, skeleton and
            neural system. Here, we show that embryos
REFERENCE   5  (bases 1 to 4403)
  AUTHORS   Wei,Q., Zhang,Y., Li,Y., Zhang,Q., Ling,K. and Hu,J.
  TITLE     The BBSome controls IFT assembly and turnaround in cilia
  JOURNAL   Nat Cell Biol 14 (9), 950-957 (2012)
   PUBMED   22922713
REFERENCE   6  (bases 1 to 4403)
  AUTHORS   Jiang,S.T., Chiou,Y.Y., Wang,E., Chien,Y.L., Ho,H.H., Tsai,F.J.,
            Lin,C.Y., Tsai,S.P. and Li,H.
  TITLE     Essential role of nephrocystin in photoreceptor intraflagellar
            transport in mouse
  JOURNAL   Hum Mol Genet 18 (9), 1566-1577 (2009)
   PUBMED   19208653
REFERENCE   7  (bases 1 to 4403)
  AUTHORS   Efimenko,E., Blacque,O.E., Ou,G., Haycraft,C.J., Yoder,B.K.,
            Scholey,J.M., Leroux,M.R. and Swoboda,P.
  TITLE     Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a
            component of the intraflagellar transport machinery in sensory
            cilia
  JOURNAL   Mol Biol Cell 17 (11), 4801-4811 (2006)
   PUBMED   16957054
REFERENCE   8  (bases 1 to 4403)
  AUTHORS   Blewitt,M.E., Vickaryous,N.K., Hemley,S.J., Ashe,A., Bruxner,T.J.,
            Preis,J.I., Arkell,R. and Whitelaw,E.
  TITLE     An N-ethyl-N-nitrosourea screen for genes involved in variegation
            in the mouse
  JOURNAL   Proc Natl Acad Sci U S A 102 (21), 7629-7634 (2005)
   PUBMED   15890782
REFERENCE   9  (bases 1 to 4403)
  AUTHORS   Lin,B., White,J.T., Utleg,A.G., Wang,S., Ferguson,C., True,L.D.,
            Vessella,R., Hood,L. and Nelson,P.S.
  TITLE     Isolation and characterization of human and mouse WDR19,a novel
            WD-repeat protein exhibiting androgen-regulated expression in
            prostate epithelium
  JOURNAL   Genomics 82 (3), 331-342 (2003)
   PUBMED   12906858
  REMARK    GeneRIF: Expressed in normal and neoplastic prostate epithelium and
            is regulated by androgenic hormones.
REFERENCE   10 (bases 1 to 4403)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132222.3 and AC138654.4.
            
            On Jul 31, 2007 this sequence version replaced NM_153391.1.
            
            Transcript Variant: This variant (2) differs in the 3' UTR compared
            to variant 1. Variant 1 and 2 both encode the same isoform (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY029258.1, SRR9219379.4716.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AC132222.3         166488-166552
            66-157              AC132222.3         169352-169443
            158-223             AC132222.3         169744-169809
            224-349             AC132222.3         173202-173327
            350-465             AC138654.4         44542-44657
            466-581             AC138654.4         47530-47645
            582-662             AC138654.4         52163-52243
            663-775             AC138654.4         53346-53458
            776-949             AC138654.4         53717-53890
            950-1020            AC138654.4         54756-54826
            1021-1193           AC138654.4         55238-55410
            1194-1308           AC138654.4         55496-55610
            1309-1415           AC138654.4         56415-56521
            1416-1538           AC138654.4         57018-57140
            1539-1688           AC138654.4         58771-58920
            1689-1836           AC138654.4         59913-60060
            1837-2041           AC138654.4         60183-60387
            2042-2201           AC138654.4         62683-62842
            2202-2312           AC138654.4         63005-63115
            2313-2422           AC138654.4         65824-65933
            2423-2480           AC138654.4         71285-71342
            2481-2621           AC138654.4         72582-72722
            2622-2704           AC138654.4         72799-72881
            2705-2788           AC138654.4         73240-73323
            2789-2935           AC138654.4         75046-75192
            2936-3060           AC138654.4         75847-75971
            3061-3173           AC138654.4         77523-77635
            3174-3242           AC138654.4         79188-79256
            3243-3320           AC138654.4         80517-80594
            3321-3417           AC138654.4         82626-82722
            3418-3542           AC138654.4         84006-84130
            3543-3624           AC138654.4         86778-86859
            3625-3775           AC138654.4         88008-88158
            3776-3899           AC138654.4         88729-88852
            3900-3976           AC138654.4         89463-89539
            3977-4101           AC138654.4         89831-89955
            4102-4403           AC138654.4         91841-92142
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 33.58 cM"
     gene            1..4403
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /note="WD repeat domain 19"
                     /db_xref="GeneID:213081"
                     /db_xref="MGI:MGI:2443231"
     exon            1..65
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..4085
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /note="isoform a is encoded by transcript variant 2; WD
                     repeat membrane protein PWDMP; WD repeat-containing
                     protein 19; intraflagellar transport 144 homolog"
                     /codon_start=1
                     /product="WD repeat-containing protein 19 isoform a"
                     /protein_id="NP_700440.2"
                     /db_xref="CCDS:CCDS51509.1"
                     /db_xref="GeneID:213081"
                     /db_xref="MGI:MGI:2443231"
                     /translation="MKRVFSLLEKSWLGAPIQFAWQKSSGNYLAVTGADYIVKIFDRH
                     GQKRSEISLPGNCVTMDWDKDGDILAVIAEKSSCIYLWDANTNKTSQLDNGMRDQMSF
                     LLWSKIGSFLAVGTIKGNLLIYNHQTSRKIPVLGKHTKKITCGCWNSENLLALGGEDK
                     MITVSNQEGDTIRQTPVKSEPSDIKFSMSKTDERISSAENTISAVVGKKMLFLFHLNE
                     PDNPVDLEFQQAYGNIVCYSWYGDGYIMIGFSRGTFLAISTHFPEVGQEIFKARDHKD
                     NLTSVALSQTLNKAATCGDNCIKIHDLTELRDMYAIINLDDENKGLGTLSWTDDGQLL
                     ALSTQRGSLHVFLTKLPILGDACHTRIAYLTSLLEVTVANLIEGEPPITVSVDVEPTF
                     VAVGLYHLAVGMNNRAWFYVLGENVVKKLKDVEYLGTVASICLHSDYAAALFEGKIQL
                     HLIENEMLDAQEERETRLFPAVDDKCRILCHALTSDFLIYGTDTGIIHYFFIEDWQFV
                     NDYRHPVGVKKLFPDPNGTRLVFIDEKSDGFVYCPVNDATYEIPDFSPTIKGVLWENW
                     PMDKGVFIAYDDDKVYTYAFHKDTIQGSKVILAGSTKLPFSHKPLLLYNGELTCQTQS
                     GKINSIYLSTHSFLGSMKDTEPTDLRQMLTQTLLLKRFSDAWDICKMLNDRTSWSELA
                     KACLHHMEVEFAIRVSRTMGDVGTVMSLEQIKGIEDYNLLAGHLAMFTNDFNLAQDLY
                     LASNCPVAALEMRRDLQHWDSALQLAKRLAPDQIPFISKEYAIQLEFTGDYVNALAHY
                     EKGITGDNKEHDEVCLAGVAQMSIRMGDIRRGANQALKHPSRVLKRDCGAILENMKQF
                     SEAAQLYEKGQYYDRAASVYIRCKNWAKVGELLPHVSSPKIHLQYAKAKEADGRYKEA
                     VVAYENAKQWNSVIRIYLDHLNNPEKAVSIVRETQSLDGAKMVARFFLQLGDYGSAIQ
                     FLVLSKCNNEAFTLAQQHNKMEIYADIIGAEDTTNEDYQSIALYFEGEKRHFQAGKFF
                     LLCGQYSRALKHFLKCPSSEDNVAIEMAIETVGQAKDELLTNQLIDHLMGESDGMPKD
                     AKYLFRLYMALKQYREAARTAIIIAREEQSAGNYRNAHDVLFSMYAELKAQKIKIPSE
                     MATNLMILHSYILVKIHVKSGDHMKGARMLIRVANNISKFPSHIVPILTSTVIECHRA
                     GLKNSAFSFAAMLMRPEYRNKIDAKYKKKIEAMVRRPDTSETEEATTPCPFCQFLLPE
                     CELLCPGCKNNIPYCIATGRHMLKDDWTMCPHCGFPALYSEFKILLNSESTCPMCSER
                     LNSSQLKKITDCSQYLRTEME"
     exon            66..157
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            158..223
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            224..349
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            350..465
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            466..581
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            582..662
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            663..775
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            776..949
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1020
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1193
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1308
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1309..1415
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1538
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1688
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1836
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..2041
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2201
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2312
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..2422
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2480
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2481..2621
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2704
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2788
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2789..2935
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            2936..3060
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3061..3173
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3174..3242
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3243..3320
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3417
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3418..3542
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3543..3624
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3625..3775
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3776..3899
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3900..3976
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            3977..4101
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     exon            4102..4403
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4376..4381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /note="hexamer: AATAAA"
     polyA_site      4403
                     /gene="Wdr19"
                     /gene_synonym="C330027H04Rik; D330023L08Rik; DYF2; Ift144;
                     mKIAA1638; PWDMP"
                     /note="major polyA site"
ORIGIN      
        1 ggggtgttct gttgcgcctg cgcacttaca agaacggggg tgtcgctgga gcctttgaaa
       61 tgaagcgtgt tttctccctg ctagaaaagt cttggcttgg tgctccgata caatttgcct
      121 ggcaaaaatc atcaggaaac taccttgcag taacaggagc tgattatatt gttaaaatct
      181 ttgatcgcca tggccaaaaa agaagtgaaa ttagcttgcc tggcaactgt gttaccatgg
      241 attgggataa agatggcgat atcctggcag tgattgctga gaagtctagt tgcatttatc
      301 tatgggatgc caacacaaat aaaaccagcc agctggacaa tggcatgagg gatcaaatgt
      361 ctttccttct ttggtcaaaa attggaagtt tcctggctgt tgggaccatt aaaggaaatt
      421 tgctcattta taatcatcag acatctcgaa agattcctgt tcttggaaaa catactaaga
      481 aaatcacatg tggatgttgg aattcagaga atctccttgc tttgggaggt gaagataaaa
      541 tgattacagt tagtaaccag gaaggcgaca caataagaca gaccccagtg aaatcagagc
      601 caagcgacat caagttctcc atgagcaaga cagatgagcg aatttcttct gctgagaaca
      661 caataagtgc agtggttggc aagaaaatgc tgtttctttt tcatctgaat gaaccagata
      721 acccggtgga tctggagttt cagcaagcct atggcaacat tgtctgctat agttggtatg
      781 gagatggcta catcatgatt ggcttttccc gagggacgtt tttggctatt tctactcact
      841 ttccggaagt tgggcaagag atatttaagg ctcgtgacca taaggataat ctaaccagtg
      901 tggccttgtc acagactctg aacaaagctg ccacatgtgg cgataactgc ataaaaatcc
      961 atgatctgac agaattgaga gacatgtatg ctataattaa tctggatgat gagaataaag
     1021 ggctgggtac cttatcctgg actgatgatg gtcagttgct agcactgtct acccaaagag
     1081 gctcactgca tgtcttcctg accaagttgc ccatcctcgg ggacgcctgt cacacaagga
     1141 ttgcgtatct cacctccctc cttgaggtca ccgtggccaa cctcattgaa ggagagccgc
     1201 caatcacagt ctctgtggat gtggaaccca cctttgtcgc agtagggctc tatcatctgg
     1261 ccgtggggat gaataaccgg gcttggtttt atgtccttgg tgaaaatgtt gtcaaaaagt
     1321 taaaagatgt ggaatatctg ggaaccgtgg ccagcatctg ccttcattct gactacgccg
     1381 ctgcactctt tgaaggcaaa atccagttac atttgataga aaatgaaatg ttggacgctc
     1441 aggaagagcg tgagactcgg ctctttccag cagtggatga taagtgccgg attttatgcc
     1501 acgccctaac tagtgatttc ctcatctacg gaactgatac tggcatcatt cactatttct
     1561 tcatcgaaga ctggcagttc gttaatgatt accggcatcc tgttggtgtg aagaagctat
     1621 ttcctgatcc aaatggaacc agattggttt tcattgatga gaagagtgat ggatttgttt
     1681 actgtcctgt taatgatgcg acctatgaga ttccagactt ctcaccaacc attaaaggtg
     1741 ttctttggga aaactggccg atggacaaag gtgtctttat cgcctatgat gatgacaagg
     1801 tgtatacata tgcgtttcac aaggacacca tccaaggatc caaggttatt ttggctggca
     1861 gcaccaaact tcccttctcc cataagcctt tgctgttata caatggagaa ctgacctgcc
     1921 agacacagag tgggaaaatc aactccatct acctcagcac ccacagcttc cttggcagca
     1981 tgaaagacac ggagcctact gacctgaggc aaatgctgac gcagaccctg ctgctcaagc
     2041 ggttttctga tgcttgggat atatgcaaga tgctaaatga ccgcacttcg tggagtgagc
     2101 tggccaaagc ctgtctgcat cacatggagg tggagtttgc tatccgagtg tcccggacaa
     2161 tgggggatgt tggcacagtg atgtcgttgg aacaaataaa gggaatcgag gactacaatc
     2221 ttttggcagg acatctcgcc atgtttacta atgacttcaa cctggcccag gacctgtacc
     2281 tggcatccaa ctgccctgtg gcagccctgg agatgcggcg ggacctgcag cactgggaca
     2341 gcgctctgca gctggcaaag cgcctggccc cggaccagat acccttcata tccaaagagt
     2401 acgccatcca gctggagttc acaggcgatt atgtaaacgc tctggctcat tacgagaagg
     2461 gcatcaccgg tgataataag gaacacgacg aagtgtgcct ggccggagtg gctcagatgt
     2521 ccattcgaat gggggacatc cgcagagggg ctaaccaagc cctcaagcac cccagcaggg
     2581 tcctcaaaag agactgtgga gccattctgg agaacatgaa gcaattttca gaagctgccc
     2641 agctgtacga aaagggccaa tattatgaca gagctgcctc ggtctacatc cgctgcaaga
     2701 actgggcaaa agttggcgaa cttctccctc atgtctcctc tcctaagatc cacttgcagt
     2761 atgccaaagc caaggaggca gacggaaggt acaaggaagc cgtggtggcg tatgaaaatg
     2821 caaagcaatg gaacagtgtc atccgcatct acctggacca cctcaacaac cccgaaaagg
     2881 ccgtgagcat cgtcagagag acccagtctc tggacggagc caagatggta gccaggttct
     2941 ttctgcagct tggtgactat gggtctgcca tccagtttct ggttctgtcc aaatgtaaca
     3001 atgaagcctt caccttggct cagcagcaca acaaaatgga aatctacgca gacatcattg
     3061 gtgctgaaga cacaactaat gaagactatc aaagtatcgc cttatatttt gaaggagaaa
     3121 aaagacattt tcaggctgga aaattcttct tactgtgtgg ccagtattca cgggcactaa
     3181 agcacttcct gaaatgccca agctcagaag ataatgtggc aatagaaatg gcaatcgaaa
     3241 ctgtgggcca ggccaaagat gaactgctga ccaatcagct gatcgaccac ctgatggggg
     3301 agagcgatgg catgccaaag gacgccaagt acctgttccg cttgtacatg gcgctaaagc
     3361 agtaccgtga agcagcccgg accgccatca tcatcgccag agaagagcag tctgcaggaa
     3421 actatcggaa tgcacacgat gttcttttca gtatgtacgc agaacttaaa gcccagaaga
     3481 tcaagatccc ctccgaaatg gccaccaacc tcatgatcct gcacagttac attctcgtga
     3541 agattcatgt taagagtgga gaccatatga agggagcgcg catgctcatt cgggtggcca
     3601 acaatatcag caagttccca tcacacatcg tgcctatcct gacgtctact gtgattgagt
     3661 gtcatagggc aggcctgaaa aactctgcct tcagctttgc agctatgctg atgaggcctg
     3721 aataccgcaa caaaattgat gccaagtaca aaaagaaaat tgaggcgatg gtcaggagac
     3781 ccgatacttc agagacagaa gaggccacca ccccatgtcc attctgccag tttcttctcc
     3841 cagaatgtga gctcctctgt cctggctgta aaaacaacat tccctattgc attgcaacag
     3901 gccgacacat gttgaaagac gactggacaa tgtgcccgca ttgtggcttc cctgctctgt
     3961 actcagaatt caagatctta ctaaacagtg aaagcacgtg tcctatgtgt tcagaaagat
     4021 taaactccag tcaactgaaa aaaattacag actgctcgca gtacctacgg acagagatgg
     4081 aatagtgagc cgcaggccca gacagtgctc ccgagtagat ggcacctctc ctggggaggc
     4141 tgtgtccacc cctggagaca taaaagaatg attctccttg gagtcagaaa catgagccag
     4201 gccagcacgt tcagcctctg cagtgacagt gactcggtga cacaaccgct gttcacccaa
     4261 atctgcgtac ttcctcttca aagtcctgtg tgttctgtgc tctgtactat taatagtata
     4321 tgattgtaaa tactaagttt tttaaataac ttttatattt aagtatctcc tttaaaataa
     4381 aattgttgac tagatacatc taa
//
