LOCUS       NM_001372370            4555 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat domain 17 (Wdr17), transcript variant 4,
            mRNA.
ACCESSION   NM_001372370 XM_006509428
VERSION     NM_001372370.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4555)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4555)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4555)
  AUTHORS   Stohr,H., Mohr,N., Frohlich,S., Mehdi,S.Q., Bhattacharya,S.S. and
            Weber,B.H.
  TITLE     Cloning and characterization of WDR17, a novel WD repeat-containing
            gene on chromosome 4q34
  JOURNAL   Biochim Biophys Acta 1579 (1), 18-25 (2002)
   PUBMED   12401215
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109200.13 and AC102933.6.
            
            On Aug 30, 2019 this sequence version replaced XM_006509428.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.15421.1,
                                           SRR9219380.7082.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                AC109200.13        45262-45342         c
            82-187              AC109200.13        24808-24913         c
            188-316             AC109200.13        17243-17371         c
            317-500             AC109200.13        14031-14214         c
            501-731             AC109200.13        10978-11208         c
            732-983             AC109200.13        8500-8751           c
            984-1106            AC102933.6         170823-170945       c
            1107-1291           AC102933.6         166773-166957       c
            1292-1460           AC102933.6         158957-159125       c
            1461-1552           AC102933.6         157912-158003       c
            1553-1635           AC102933.6         155728-155810       c
            1636-1722           AC102933.6         153776-153862       c
            1723-1887           AC102933.6         150393-150557       c
            1888-2090           AC102933.6         148276-148478       c
            2091-2240           AC102933.6         146860-147009       c
            2241-2371           AC102933.6         146643-146773       c
            2372-2497           AC102933.6         146199-146324       c
            2498-2653           AC102933.6         145011-145166       c
            2654-2718           AC102933.6         142622-142686       c
            2719-2851           AC102933.6         139306-139438       c
            2852-2943           AC102933.6         136714-136805       c
            2944-3043           AC102933.6         134560-134659       c
            3044-3183           AC102933.6         133647-133786       c
            3184-3295           AC102933.6         128541-128652       c
            3296-3437           AC102933.6         125263-125404       c
            3438-3540           AC102933.6         124828-124930       c
            3541-3642           AC102933.6         123714-123815       c
            3643-3741           AC102933.6         120872-120970       c
            3742-3925           AC102933.6         117740-117923       c
            3926-4555           AC102933.6         114708-115337       c
FEATURES             Location/Qualifiers
     source          1..4555
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 29.28 cM"
     gene            1..4555
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="WD repeat domain 17"
                     /db_xref="GeneID:244484"
                     /db_xref="MGI:MGI:1924662"
     exon            1..81
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            82..187
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..4045
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="isoform 4 is encoded by transcript variant 4"
                     /codon_start=1
                     /product="WD repeat-containing protein 17 isoform 4"
                     /protein_id="NP_001359299.1"
                     /db_xref="GeneID:244484"
                     /db_xref="MGI:MGI:1924662"
                     /translation="MAWMTYVSHWFEQDDWYEGLQRATMSQVRQVGLLAAGCQPWNKD
                     VCAANGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASS
                     STDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDAVAFVSQKGPLLIWTISGPD
                     SGVSVHKEAHSFASDICIFRWHTQKKGKVAFGHIDGSISIFQPGSKNQKHVLRPDSLE
                     GTDEEDPVTALEWDPLSTDYLLVANLHFGIRLLDSESLYCITTFNLPSAAVSVQCLAW
                     VPSAPGMFITGDSQVGVLRIWNVSRTTPIDNFKLKKTGFHCFHVVNSPPKKKFSVQSP
                     NKNHYISSTSEAVPPPNLTQNQAFSLPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGH
                     VETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLN
                     CIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIR
                     TVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHT
                     ARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYL
                     LISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL
                     IPLITPLQINILADRSWDEVIGNTDNAIRQDCPPLLCGKVSRDIKQEVEKLTCNPRAK
                     KLRLFSECLSPPGGSDNLWNLVSVIKGQDDSLLPQNYCKGMMHLKHLIKFRTSEAQEL
                     TTIKMSKFGGGVGAPTKEKKLKEAAEIHLRLGQIQRYCELMVELGEWDKALSVAPGVS
                     VKYWRKLMQRRADQLIQEDKDDVIPYCIATGDVKKLVNFFVSRGQLKEALLVAQAACE
                     GNMQNAHVSTPKGASNSDDIHKEDFNELLHKVINELAEWYFQDGQAVLAACCHLAVDD
                     IELAMAYLIRGNELELAVSVGTVLGEPAAPAMHYALQLLATKCMMIPMWNLAADLLLM
                     TPGSEVHLVKLCAFYPGCIEEINDLHKKCNLPPAEECTQLAETARADGNVFETIKYYL
                     LSQEPEKALPIGIDFVKGCISNSNWTLDTVYPVLDLMSYIRTEKLLLHTCTEARNELL
                     ILCGYIGALLAIRRQYQSIVPSLYEYTSQLLKRRVVSVPLKIEHLSEELDAWRACTQS
                     TKQSSEDSPYTPPSDSQRTVYETLLKRLKEEPLKGITGLDYVTGSNLPSHSDIHISCL
                     TGLKIQGPVYFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF"
     exon            188..316
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            317..500
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            501..731
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            732..983
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1106
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1291
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1460
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1552
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1635
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1722
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1887
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..2090
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2240
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2241..2371
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2372..2497
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2653
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..2718
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2719..2851
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2852..2943
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2944..3043
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3044..3183
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3184..3295
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3296..3437
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3438..3540
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3541..3642
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3643..3741
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3925
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3926..4555
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4175..4180
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="hexamer: ATTAAA"
     regulatory      4202..4207
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="hexamer: AATATA"
     polyA_site      4210
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="major polyA site"
     polyA_site      4223
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="major polyA site"
     regulatory      4533..4538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4555
                     /gene="Wdr17"
                     /gene_synonym="3010002I12Rik; B230207L18Rik"
ORIGIN      
        1 gcgcgggcca gggcggtccc tttggccggt cctgcttcag cacctgcggt tgtccagagc
       61 tgcaactgct gtctccttca ggcgctgact gttctccagc tgacttgatt aaagtgcaaa
      121 tatggcttgg atgacttacg tttcccattg gtttgagcaa gatgattggt atgaaggact
      181 ccaaagagca accatgtccc aggtcaggca agtgggactt ctggctgctg gatgtcaacc
      241 atggaacaaa gatgtatgtg ctgccaacgg agatcggttt gcatactgcg caactctggc
      301 catctacata taccagctgg atcaccgtta taatgaattc aaacttcatg caattatgtc
      361 ggaacataaa aaaacaatca cggcaatttc ctggtgtcca cataaccctg acctgtttgc
      421 aagcagcagt accgataact tagtgatcat ttggaacgtg gctgagcaaa aagtcattgc
      481 taaactcgac aacatcaaag agacacctgc ctgcctcggc tggtgctgga acacacatga
      541 tgctgtggca ttcgtttccc agaagggtcc tctgctcatt tggaccatct cagggccaga
      601 tagtggagtg tctgtgcaca aagaagccca tagttttgcg tctgacattt gcatatttag
      661 gtggcacacc caaaagaaag gaaaagttgc atttggtcac attgatggaa gcatatcgat
      721 ttttcagcct ggtagcaaaa atcagaaaca tgttctgaga ccggactctc ttgaaggaac
      781 agatgaggag gaccctgtta cagccctgga gtgggaccca ctgtccacag attatcttct
      841 ggtggctaat ttgcattttg gaattcgtct tctggactct gaatcccttt actgcatcac
      901 aacgtttaat cttcccagtg ctgcagtgtc tgtgcagtgc ttggcctggg ttcccagtgc
      961 tccaggcatg tttataactg gagattctca agtgggcgtt ttacgcattt ggaatgtttc
     1021 aagaacaaca cctattgata attttaaatt aaagaaaaca ggatttcact gctttcatgt
     1081 agttaattct cctccaaaga aaaaattttc cgtccagtct ccaaacaaaa atcattatat
     1141 atcttcaaca agtgaagcag ttccaccccc aaatttgaca cagaatcaag cattttctct
     1201 tccccctggt catgtcgtat gctgtttcct ggatggtgga gttggacttt atgacatggg
     1261 agccaagaag tgggattttc ttagagaact gggacacgtg gaaactatat ttgactgcaa
     1321 attcaaacct gatgatccaa atgttttagc aacagcttca tttgatggca ctataaaggt
     1381 gtgggatata aacacattaa cagcagtgta tacctctccg ggtaacgaag gggtcatttt
     1441 tgctctttct tgggctccag gtgatttaaa ttgcattgct ggtgcaactt ccagaaatgg
     1501 cgcttttatt tgggatattc aaaagggcaa aataatacag cgatttaatg agcatggaaa
     1561 aaatggaata ttctatattg cctggagtca taaagattct aaacgaatag caacttgcag
     1621 tggcgatggt ttttgcatta ttcgaacagt cgatggtaaa ctactgcaca aatacaaaca
     1681 cccggctgca gtgtttggct gtgattggag ccaaaacaac aaagacatga tagccactgg
     1741 ctgtgaagac aaaaacatcc gtgtctttta tgtagccacg agctctaatc agcccttgaa
     1801 agtgtttagc gggcacacag caagagtgtt ccatgttaag tggtctcctc tgagggaagg
     1861 aattctctgc agtggttctg atgatggctc tgttcgaatc tgggattata ctcaagatgc
     1921 ttgcgtaagc actcttaatg gacacactgc acctgtgagg gggttaatgt ggaatactga
     1981 gattccatac ctactaatct ctggaagctg ggactatact atcaaagtgt gggatactcg
     2041 aggaggagtt tgcctagata ctgtgtatga tcacggtgca gacgtttatg gtttaacttg
     2101 ccatccaagt cgtcccttca cgatggcttc ctgctcccga gattctacag tgagactctg
     2161 gtcattaata cctttaatca cccctttaca aataaatatt ctggcagaca gatcttggga
     2221 cgaagttatc ggaaacactg ataatgcgat acgtcaagac tgtcctcctc tcctctgcgg
     2281 caaagtgtca agagacatta aacaagaagt agaaaaacta acgtgcaacc ctcgggcgaa
     2341 aaagctaaga ctgttttcag aatgtttatc acctccaggt ggcagtgaca acttgtggaa
     2401 cttggtgtcc gtgattaaag gacaagatga cagcttgctc cctcagaact actgcaaagg
     2461 aatgatgcat ttgaaacacc tgatcaaatt tagaacctca gaagcccaag aactaacgac
     2521 aatcaagatg tctaaatttg gtggtggtgt tggcgcacct actaaggaga aaaaactgaa
     2581 ggaagctgct gaaatccacc tgagattagg acaaatacag agatactgtg aactcatggt
     2641 cgaacttgga gagtgggaca aagccctatc agttgcacct ggggtctctg tgaaatactg
     2701 gagaaagtta atgcagagga gagctgacca gttaattcag gaagataagg atgatgtcat
     2761 tccatactgt atagccactg gggatgtgaa aaagctcgtc aatttttttg tgtccagggg
     2821 tcagcttaaa gaagcactgc ttgttgcaca ggctgcctgt gagggaaata tgcaaaatgc
     2881 ccatgtttct acaccaaaag gagcttcaaa ctctgatgat atccacaaag aagactttaa
     2941 tgaactctta cacaaagtca taaatgagct ggccgaatgg tattttcagg atggccaagc
     3001 tgtgttggct gcgtgctgcc atcttgctgt agatgatatt gagcttgcta tggcatacct
     3061 gatccgtggg aatgaactag agctggcggt ctcagtgggc actgtcctag gagaacccgc
     3121 agccccagca atgcattatg ccctgcagct actggcgaca aaatgcatga tgattccaat
     3181 gtggaacctg gcagctgatc ttctcctgat gactcctggt agcgaagtcc acttagtaaa
     3241 actctgtgcc ttctaccctg ggtgcatcga agaaatcaat gaccttcaca agaagtgcaa
     3301 tctaccccct gcagaagaat gcactcagtt ggctgaaaca gcccgggcag atggcaatgt
     3361 atttgaaacc ataaagtatt atttactaag tcaagaacct gaaaaggctc ttcctattgg
     3421 tattgacttt gtcaaaggat gtatcagtaa ctcaaactgg actctagata ctgtttaccc
     3481 tgtgcttgac ctgatgagtt atatccgtac tgaaaaatta ctcttacata cgtgcactga
     3541 ggctcgaaat gaattgctta tcttatgtgg ttacatcggt gccttgctgg ctatcaggag
     3601 acagtatcaa agcattgttc cctcgctgta tgagtacacg agtcagctct taaaacgacg
     3661 agtggtgtca gtaccattaa aaattgagca tctctctgag gagctggatg catggagagc
     3721 ttgcacacaa tcgaccaaac aatcatcaga agattctcca tatacacccc cttctgactc
     3781 acaaagaaca gtttatgaaa ctttattaaa gagactgaaa gaagagccac tcaaaggaat
     3841 tactggacta gattacgtga ctggatcaaa tcttccaagc cattcagaca ttcacatctc
     3901 ttgtcttact ggactaaaaa tccagggtcc tgtgtatttc ctagaagatg gaaaatcaac
     3961 tatttctttg aatgacgctc tgatgtgggc aaaggtgaat ccattctcac ctttaggaac
     4021 tggaatacga ctcaatccat tttgactgaa tttttttctg cacacttcct agttttgtaa
     4081 aaaggaaatt tggggtattt ataaccttca ttttggtggt ctaagaataa taggttggga
     4141 ggtggtttga tacttggaag acagagggaa taatattaaa ttttgttaat ttcaaaaata
     4201 aaatatataa ttctaaagaa aaatatgtat cttattgata aatggtatta tttacattta
     4261 gaagaaagtt ttaatgaatt ataaaaacta aacaatctgc aaagcagata ggtttcaaca
     4321 gatatggata tcgacaaaat actgtattgt taaaactctg aaacacataa aataggacgt
     4381 catttggaag aggttttagc atatatacat atatagagaa gatatttaat gaatgtttga
     4441 atcaatatct tgaaataata aaatgtatgg aatagacaga tgatttgcaa ttcaacaatc
     4501 tcccatatga tcctttataa aaattagttg caaataaatt cgtttgtaaa tagga
//
