LOCUS       NM_001360532            4301 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus WD repeat and HMG-box DNA binding protein 1 (Wdhd1),
            transcript variant 1, mRNA.
ACCESSION   NM_001360532 XM_006518830
VERSION     NM_001360532.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4301)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4301)
  AUTHORS   Prakash Yadav,R., Leskinen,S., Ma,L., Makela,J.A. and Kotaja,N.
  TITLE     Chromatin remodelers HELLS, WDHD1 and BAZ1A are dynamically
            expressed during mouse spermatogenesis
  JOURNAL   Reproduction 165 (1), 49-63 (2022)
   PUBMED   36194437
  REMARK    GeneRIF: Chromatin remodelers HELLS, WDHD1 and BAZ1A are
            dynamically expressed during mouse spermatogenesis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4301)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4301)
  AUTHORS   Fan,H.H., Lee,K.H., Chen,Y.T., Lin,L.J., Yang,T.L., Lin,S.W. and
            Yu,I.S.
  TITLE     Wdhd1 is essential for early mouse embryogenesis
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1868 (6), 119011 (2021)
   PUBMED   33716172
  REMARK    GeneRIF: Wdhd1 is essential for early mouse embryogenesis.
REFERENCE   5  (bases 1 to 4301)
  AUTHORS   Simonson,L., Vold,S., Mowers,C., Massey,R.J., Ong,I.M.,
            Longley,B.J. and Chang,H.
  TITLE     Keratin 13 deficiency causes white sponge nevus in mice
  JOURNAL   Dev Biol 468 (1-2), 146-153 (2020)
   PUBMED   32758484
REFERENCE   6  (bases 1 to 4301)
  AUTHORS   Hsieh,C.L., Lin,C.L., Liu,H., Chang,Y.J., Shih,C.J., Zhong,C.Z.,
            Lee,S.C. and Tan,B.C.
  TITLE     WDHD1 modulates the post-transcriptional step of the centromeric
            silencing pathway
  JOURNAL   Nucleic Acids Res 39 (10), 4048-4062 (2011)
   PUBMED   21266480
REFERENCE   7  (bases 1 to 4301)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156016.2, AK052690.1, BY210513.1, CF163129.1, AK036390.1,
            BQ748927.1, AK160777.1 and BE980284.1.
            
            On Feb 6, 2018 this sequence version replaced XM_006518830.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927936.3169789.1,
                                           SRR1660817.159732.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AC156016.2         87492-87516
            26-28               AK052690.1         2-4
            29-368              BY210513.1         1-340
            369-421             CF163129.1         327-379
            422-3171            AK036390.1         381-3130
            3172-3681           BQ748927.1         53-562
            3682-4284           AK160777.1         732-1334
            4285-4301           BE980284.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..4301
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 24.6 cM"
     gene            1..4301
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /note="WD repeat and HMG-box DNA binding protein 1"
                     /db_xref="GeneID:218973"
                     /db_xref="MGI:MGI:2443514"
     exon            1..337
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..3617
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     acidic nucleoplasmic DNA-binding protein 1"
                     /codon_start=1
                     /product="WD repeat and HMG-box DNA-binding protein 1
                     isoform 1"
                     /protein_id="NP_001347461.1"
                     /db_xref="CCDS:CCDS88642.1"
                     /db_xref="GeneID:218973"
                     /db_xref="MGI:MGI:2443514"
                     /translation="MPATQKPMRYGHTEGHTEVCFDDSGSYIVTCGSDGDVRMWEDLD
                     DDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGVPDGILTRFTTNANHVVF
                     NGAGNKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTV
                     RVWNISDQTCAVSWPVLQKSNDVVNAKSICRLAWQPKAGKLLAVPVEKSVKLYRRETW
                     SNPFDLSDSSISQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKDCMERVKHEKGYAI
                     CGLAWHPTCSRICYTDVEGNLGVLENVCDLSGKVSSNKVSSRVEKDYNDLFDGDDTSS
                     AGDFLNDNAVEIPSFSKGIINEDDDNDDIMLAADHDLGDDENSVDVTMLKADLSHKEE
                     GDDDQARSIHNLPLIRPQRPFYDGPMPTPRQKPFQSSSTPLHLSHRFMVWNSVGIIRC
                     YNDDQDSAIDVEFHDTSIHHATHLLNAFNYTMGTLSHEAILLACESADELASKLHCLH
                     FSSWDSSKEWMVDMPQNEDIEAICLGLGWAAAATTALLLRLFTIGGVQKEVFCLPGPV
                     VSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRKKNQVLHGDPLPLTRKSYLTWLG
                     FSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRC
                     IPCKGSRFPPTLPRPAVAILSFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAKNGY
                     DYEESIKNQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRK
                     LILAQKLSELAAEKAAELAETQSEEEKEEDFREKLNAGYSHTTTEWSRPRVRSQVEDA
                     EDREDTVSEEKPESHNHGQNLFQSANSSDTPALKSGAVFSSSQGWVNPFKVVVSSKEP
                     AVSANSTRSANILDSMNKSSRKSTSLNRMENNEKSPVIKPLTPKPRSKQASAASYFQK
                     RTPQADKTEEVKENPKSSSSDAPAVCLQNSENQRPKTGFQMWLEENRSQILSDNPDIS
                     DETDIIKEGMIRFRVLSAEERKAWTNKAKGETASDGAEAKKRKRVVSEICETENQEET
                     VKENLDLSKKQKALNLPANQKLSAFAFKQE"
     exon            338..449
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            450..601
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            602..713
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            714..764
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            765..860
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            861..953
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1060
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1202
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1395
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1580
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..1765
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..2007
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2008..2145
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2302
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2417
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2418..2549
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2550..2767
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..2880
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2881..2934
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2935..2978
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2979..3149
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3150..3277
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..3416
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3417..4285
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4265..4270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4285
                     /gene="Wdhd1"
                     /gene_synonym="A630092E18; AND-1; D630024B06Rik"
                     /note="major polyA site"
ORIGIN      
        1 agggcgagcg cgccagagcg cgggaagcgg ctccgtgctt ccatcagagc agacgctggt
       61 gcacaccgct tgctcctcgc ccccgctgcc cgtgcttgca gaggggaaag cttgtcatct
      121 cccgggcgtg tgtgacatac cttccgctgc atcgtgctgt ggctcctcgg gtgagggaaa
      181 caggactgca cggcgcggag aggacgatcg ccctactgaa aaaaatacca gttcttacaa
      241 aacggctcag gtagggaaag atgccggcca cacagaagcc catgaggtac ggacatacgg
      301 aagggcacac cgaagtctgc tttgatgatt ctggaagcta tattgtgact tgtggcagtg
      361 atggtgatgt gaggatgtgg gaagacttgg acgacgatga ccctaagtcc gttaatgttg
      421 gagaaaaggc attttcatgt gctttgaaga atggaaaatt ggtcactgca gtttctaata
      481 ataccgtcca agtctataca ttccctgaag gagttcctga tggcatatta acacgcttca
      541 ctacaaatgc aaaccatgtg gtcttcaatg gggccggcaa caaaattgct gctgggtcaa
      601 gtgattttct ggtcaaagtt gtggatgtga tggataacag ccagcagcaa acatttcgag
      661 gacatgatgc ccctgtttta agtctgtctt ttgatcctaa ggatatcttt ctggcatcgg
      721 ctagttgtga tggaactgtc agggtatgga atatatctga tcagacctgt gctgtcagtt
      781 ggccagtact gcaaaagagc aatgacgtgg tgaacgccaa gtccatctgc agactcgcgt
      841 ggcagcccaa ggccgggaag ttactagcag ttcctgtgga aaaatctgtt aagctgtaca
      901 gaagagaaac ctggagtaat ccattcgatc tttcagatag ttccatctcc cagacactca
      961 atatagtaac ctggtctccc tgtgggcagt atttggctgc aggtgctatt aatggcttaa
     1021 ttgtagtttg gaatgtggaa accaaagact gcatggaaag ggtaaaacat gagaaaggtt
     1081 atgcaatttg tggcctggcc tggcatccca cttgtagtcg gatatgttat actgatgtgg
     1141 aaggaaacct tggagtcctg gaaaatgttt gtgacctcag tggaaaggtg tcgagcaata
     1201 aggtatctag tagagtggaa aaggactaca atgatctttt tgatggagat gatacaagta
     1261 gtgctggcga ttttctaaac gacaatgcgg ttgagatccc ttctttttca aagggcatta
     1321 taaatgagga tgacgataat gatgacatca tgctggctgc agatcatgac ttgggagacg
     1381 atgaaaactc agttgatgtt acaatgctaa aagctgatct ttctcacaaa gaggaagggg
     1441 acgatgatca ggcacgaagt attcacaacc tcccccttat aagaccccaa aggccatttt
     1501 atgatgggcc catgccaacc ccacgacaaa agcccttcca gtcaagttca acgcccttgc
     1561 atctctctca cagattcatg gtgtggaact ctgttgggat tattcgctgc tataacgacg
     1621 atcaagacag tgccatagac gtggagttcc atgacacctc tatccatcat gcaacacatc
     1681 tattaaatgc tttcaattac acaatgggaa ctctttccca tgaagctatt ttgttggcat
     1741 gtgaaagtgc tgatgaatta gcaagcaagc ttcattgctt gcacttcagt tcttgggact
     1801 caagcaaaga gtggatggta gatatgcccc agaatgagga catcgaagcc atatgcctcg
     1861 gtctaggctg ggccgctgct gctaccactg ccttgctcct tcgactgttc actattggag
     1921 gtgttcagaa agaagtcttc tgccttcctg gacctgtggt atccatggca ggacacggag
     1981 aacagctttg cattgtttat catagaggta cagggtttga tggagatcag tgccttggag
     2041 ttcaactact cgagctgggg cggaagaaaa accaggtttt gcatggtgac cctcttcctc
     2101 tcacacggaa atcctacctc acatggctgg gcttctctgc tgaaggtact ccctgttacg
     2161 tggattccga aggctgtgtt cgaatgctaa acagaggact cgggaataca tggactcctg
     2221 tatgcaacat aagagagcac tgcaaaggaa aatctgacca ctactgggtg gttggtatcc
     2281 atgagaatcc ccagcagcta aggtgcatcc cttgtaaagg ttctcggttt cctcccaccc
     2341 ttccacgacc tgctgtagct atattatctt ttaagcttcc ttactgtcag acttcaacag
     2401 agaaaggcca aatggaggaa caattttggc attcggttct gtttcacaac taccttgatt
     2461 acttggctaa aaatggttat gattatgagg agagcattaa aaaccaggca gtaaaagagc
     2521 agcaggaact cttaatgaaa atgcttgcgc tgtcttgtaa actggaacga gaattccgct
     2581 gtgtggaact tgctgatcta atgactcaaa atgccgtgca tttagccatt aaatatgctt
     2641 ctcgctctcg gaaattaata ttggctcaga aacttagtga acttgctgca gaaaaggcag
     2701 ctgaattggc agaaacccag tcagaagaag agaaagaaga ggatttcaga gaaaaactga
     2761 atgctggtta cagtcacacc actacagaat ggagtcggcc acgggtcaga agtcaagttg
     2821 aagatgctga ggacagagag gacactgttt ctgaagagaa accagagtca cataaccatg
     2881 ggcagaactt attccaaagt gccaattcct ctgatacacc agctcttaaa tcaggtgcag
     2941 ttttctcgag cagccaagga tgggtaaacc ccttcaaggt agtagtcagt tccaaagagc
     3001 cagccgtatc agcgaattca acacgctcag ctaacatttt agacagcatg aacaaatcat
     3061 ccaggaagtc cacttctctt aatcgaatgg aaaacaatga aaaatctcca gttataaagc
     3121 ctctcactcc caagccaagg tctaagcagg catctgcagc atcctatttc cagaaaagaa
     3181 ctccacaggc tgataagact gaggaagtaa aagaaaatcc taaaagctcg tcctctgatg
     3241 ctccagccgt gtgccttcaa aactcggaaa accaaaggcc aaagactggg ttccagatgt
     3301 ggctggaaga aaatagaagt caaattttgt ccgacaaccc tgacatttca gatgaaacag
     3361 acataataaa agaggggatg atacgattta gagtattgtc cgctgaagaa aggaaggcat
     3421 ggactaacaa agccaaggga gaaactgcca gcgatggagc tgaagcaaag aagcgaaagc
     3481 gtgtggtcag cgagatctgt gagacagaga accaggaaga aacagtgaag gagaatctag
     3541 atctttctaa aaagcaaaag gcgttaaatc ttcctgctaa ccagaaattg tcagcgtttg
     3601 catttaagca ggagtaaagg aaggattgtc tgtcaggaag tagtgagacc tggcttcagc
     3661 ttctcttgga ttctggacgt cttttaacct ttagggagta tattcttata atcctgtgtg
     3721 tttagacaca gcgtggttct cataaggcag tgtaggggct gggtgtgcag ctcagtggtg
     3781 gagggcttgc ctaagcatgc gcaggccctg gttcccttac tgccgcaaaa caacacacaa
     3841 caaagtggtg attttcctgt gtcaggaaca ccacatgtaa gagctgtctg tggggattcc
     3901 tctgctgtcc atgagcagaa atgccatgat ggcagtgact accagggaca ccattctgtc
     3961 tccgtggaag ccattatcgg taaaagtcac taaaagcctc agtcttaaga cttgttcaca
     4021 ttacagtacc tcctagggct ttcccgcctt tgtttaggtt ttgcagtaga agtgccatgg
     4081 tcatcggctt cccaagtgag atgtcataga ctgctctctt gtcaacttga cctcaggccc
     4141 atggctttta atatgggccc caatgtgtaa ataatgttgt aaatgagatg ttattttatg
     4201 tgtttggggt cgtttttcgt gttattactt tttgtatatc tgtatagact gggtcttctg
     4261 aataaataaa actttctcat ttgcaaaaaa aaaaaaaaaa a
//
