LOCUS       NM_021714               2722 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WW domain binding protein 11 (Wbp11), mRNA.
ACCESSION   NM_021714
VERSION     NM_021714.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Martin,E.M.M.A., Enriquez,A., Sparrow,D.B., Humphreys,D.T.,
            McInerney-Leo,A.M., Leo,P.J., Duncan,E.L., Iyer,K.R., Greasby,J.A.,
            Ip,E., Giannoulatou,E., Sheng,D., Wohler,E., Dimartino,C.,
            Amiel,J., Capri,Y., Lehalle,D., Mory,A., Wilnai,Y., Lebenthal,Y.,
            Gharavi,A.G., Krzemien,G.G., Miklaszewska,M., Steiner,R.D.,
            Raggio,C., Blank,R., Baris Feldman,H., Milo Rasouly,H.,
            Sobreira,N.L.M., Jobling,R., Gordon,C.T., Giampietro,P.F.,
            Dunwoodie,S.L. and Chapman,G.
  TITLE     Heterozygous loss of WBP11 function causes multiple congenital
            defects in humans and mice
  JOURNAL   Hum Mol Genet 29 (22), 3662-3678 (2020)
   PUBMED   33276377
REFERENCE   2  (bases 1 to 2722)
  AUTHORS   Llorian,M., Beullens,M., Lesage,B., Nicolaescu,E., Beke,L.,
            Landuyt,W., Ortiz,J.M. and Bollen,M.
  TITLE     Nucleocytoplasmic shuttling of the splicing factor SIPP1
  JOURNAL   J Biol Chem 280 (46), 38862-38869 (2005)
   PUBMED   16162498
  REMARK    GeneRIF: SIPP1 is a positive regulator of pre-mRNA splicing that is
            regulated by nucleocytoplasmic shuttling
REFERENCE   3  (bases 1 to 2722)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   4  (bases 1 to 2722)
  AUTHORS   Llorian,M., Beullens,M., Andres,I., Ortiz,J.M. and Bollen,M.
  TITLE     SIPP1, a novel pre-mRNA splicing factor and interactor of protein
            phosphatase-1
  JOURNAL   Biochem J 378 (Pt 1), 229-238 (2004)
   PUBMED   14640981
  REMARK    GeneRIF: Identification of SIPP1 as a pre-mRNA splicing factor and
            a binding partner of protein phosphatase-1.
REFERENCE   5  (bases 1 to 2722)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   6  (bases 1 to 2722)
  AUTHORS   Bedford,M.T., Reed,R. and Leder,P.
  TITLE     WW domain-mediated interactions reveal a spliceosome-associated
            protein that binds a third class of proline-rich motif: the proline
            glycine and methionine-rich motif
  JOURNAL   Proc Natl Acad Sci U S A 95 (18), 10602-10607 (1998)
   PUBMED   9724750
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122804.4 and AK041079.1.
            
            On Nov 13, 2009 this sequence version replaced NM_021714.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006600.1, AK153044.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AC122804.4         89067-89204
            139-2516            AK041079.1         78-2455
            2517-2722           AC122804.4         103424-103629
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 66.72 cM"
     gene            1..2722
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /note="WW domain binding protein 11"
                     /db_xref="GeneID:60321"
                     /db_xref="MGI:MGI:1891823"
     exon            1..197
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            198..306
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            307..338
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            339..432
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            433..629
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            630..763
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..963
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1155
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1257
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1551
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1734
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..2722
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2699..2704
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /note="hexamer: AATAAA"
     polyA_site      2722
                     /gene="Wbp11"
                     /gene_synonym="2510026P17Rik; D6Wsu113e; Npwbp; SIPP1"
                     /note="major polyA site"
ORIGIN      
        1 gggcccagtg cctggcaacg cggtgagatc gcggccagcg ggaacaggaa gtgacgtgag
       61 ctggcggagg ggcgcgaggt ttcaagatgg cggttcccgg gtggttgacc gaggggcaga
      121 ggtgaaggcc ccttcgcaga gagtcctccg ggaccgcccg ctagctgctc tcgccgtccc
      181 gggagcctcg cagtcgtttt tttttttttt taatgaagaa gtaaatcata taaattgtca
      241 ccatgggacg aagatcaaca tcctccacca agagtgggaa gtttatgaac cccacagacc
      301 aagcccgaaa ggaagcccga aaaagagaac tgaaaaagaa caaaaaacag cgcatgatgg
      361 tccgggctgc agttttgaag atgaaagacc ccaaacaaat tatccgggac atggagaaat
      421 tggatgaaat ggagtttaac ccagtgcagc agccacagtt gaatgagaaa gtactgaaag
      481 acaagcgaaa aaagctgcgg gaaacctttg aacgcattct acgcctttat gaaaaagaaa
      541 acccagatat ttacaaagaa ctgagaaagc tggaagtgga atatgaacag aagagagctc
      601 agctgagcca gtactttgat gctgttaaga atgctcagca tgtggaagta gagagcatcc
      661 ctttgccaga catgccgcat gctccttcca acatcttgat ccaggacatt cctcttcctg
      721 gtgcacagcc cccctccatc ctgaagaaaa cctcagcgta tgggcctcca gctcgggccg
      781 tgtctatcct tcctctcctg ggacatggtg ttccccgctt gccccctggc agaaaaccgc
      841 ccggccctcc acctggcccc cctcctcctc aggttctgca gatgtacggc cggaaagtgg
      901 gcttcgctct agatcttccc cctcggaggc gagatgagga catgctgtat agtccagagc
      961 ttgctcagcg gggtcatgac gatgacatgt ccagcaccag tgaagacgac ggctatcctg
     1021 aggacatgga tcaggataag catgatgaca gtactgagga cagtgacact gacaggtcag
     1081 atgcagagag tgacggggat gagttcgggc accgcgagga cagtgagcgc gacaacactg
     1141 aggagaagaa gtcaggtcta agcgtcagat ttgctgatat gcctgggaaa tcaaggaaga
     1201 agaagaaaaa catgaaggag ctgactcctc ttcaagccat gatgctgcga atggcaggtc
     1261 aggaaatccc tgaggaagga cgggaagtgg aggaattttc agaggaggag gatgccgacg
     1321 actcggatga ttctgaagcc gagaagcagt cgcagaagca gcataaagac gatggccact
     1381 ctgacagcac ggctgcagcc tcttcccagc agcaggctcc tccacagtct gctcctgctt
     1441 ctcagataca agcccctccc atgccaggac caccacctct tggaccacca cctgccccac
     1501 ccttacggcc tcctggacca cctacaggcc ttcctcctgg gccgcctcca ggggctcctc
     1561 cattcctgag accacctgga atgccaggaa tccgagggcc tttaccacga cttttacctc
     1621 caggaccacc accaggccga cctcctggcc ctcccccagg cccacctcca ggtctgcccc
     1681 ctggaccccc tcctcgggga cccccaccaa ggctacctcc tcctgcacct ccaggtatcc
     1741 ctcctcctcg tcctggcatg atgcgcccac ccttggttcc tcctcttgga cctgccccgc
     1801 ctggcctttt cccaccagct cccttgccca acccaggggt gttgagtgcc ccacccagcc
     1861 tcattcagcg accgaaggcg gatgatgcaa gtgccgccac catcgagaag aaagccacag
     1921 cgaccatcag tgccaagccc cagatcacca atcccaaggc agaggtcaca cggtttgtgc
     1981 ccactgcact gagggtacgc cgagagaata agggggctac tgctgttccc caaagaaggt
     2041 cagaggatga ctctgctgtg cctgttgcca aagcagcccc gagatctggt ccttcagttg
     2101 ctgtctcagt acaaactaag gacgatgttt atgaagcctt tatgaaagag atggaagggc
     2161 tgctgtgaca gggcctcctg ccaggacagg cttctgttca gagtactggt ttgtggaaca
     2221 agaggctctt attacagtga agagcaatgt ccactgtcag gtgttttcca agtccagttc
     2281 caggagcctc ctcatgtttg cctgctggga tccctgcaca aggtgtttct ttacaataga
     2341 ccaggatgtg aagcactgct gctaacccct gctccctgtg acatcaccat ctcctccctc
     2401 tcttcctctc tccattttgg gaattctgtc agcgaggtct tagttacttg tttttgactc
     2461 atgtgccgtg ggcactagag tagagaattc tggaggaaaa aagtttattt catcttgact
     2521 tttgtgtttg agttattttt aatattttcc tgtaaatatt ttgtaatatt ttccttgtag
     2581 tgaaatggat tacagtatca tttcctaatt caaaacagga tatgtgggaa gaaaatatac
     2641 aattctggga ttaaagttac ttcccacaag ctaaactctt ttgagtgttt catggacaaa
     2701 taaaatgttc cataccaaga ta
//
