LOCUS       NM_016757               1338 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus WW domain binding protein 1 (Wbp1), transcript variant
            1, mRNA.
ACCESSION   NM_016757
VERSION     NM_016757.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1338)
  AUTHORS   Morishima,N., Nakanishi,K. and Nakano,A.
  TITLE     Activating transcription factor-6 (ATF6) mediates apoptosis with
            reduction of myeloid cell leukemia sequence 1 (Mcl-1) protein via
            induction of WW domain binding protein 1
  JOURNAL   J Biol Chem 286 (40), 35227-35235 (2011)
   PUBMED   21841196
  REMARK    GeneRIF: Mcl-1 is a determinant of cell fate, and ATF6 mediates
            apoptosis via specific suppression of Mcl-1 through up-regulation
            of WBP1
REFERENCE   3  (bases 1 to 1338)
  AUTHORS   Jolliffe,C.N., Harvey,K.F., Haines,B.P., Parasivam,G. and Kumar,S.
  TITLE     Identification of multiple proteins expressed in murine embryos as
            binding partners for the WW domains of the ubiquitin-protein ligase
            Nedd4
  JOURNAL   Biochem J 351 Pt 3 (Pt 3), 557-565 (2000)
   PUBMED   11042109
REFERENCE   4  (bases 1 to 1338)
  AUTHORS   Gavva,N.R., Gavva,R., Ermekova,K., Sudol,M. and Shen,C.J.
  TITLE     Interaction of WW domains with hematopoietic transcription factor
            p45/NF-E2 and RNA polymerase II
  JOURNAL   J Biol Chem 272 (39), 24105-24108 (1997)
   PUBMED   9305852
REFERENCE   5  (bases 1 to 1338)
  AUTHORS   Chen,H.I., Einbond,A., Kwak,S.J., Linn,H., Koepf,E., Peterson,S.,
            Kelly,J.W. and Sudol,M.
  TITLE     Characterization of the WW domain of human yes-associated protein
            and its polyproline-containing ligands
  JOURNAL   J Biol Chem 272 (27), 17070-17077 (1997)
   PUBMED   9202023
REFERENCE   6  (bases 1 to 1338)
  AUTHORS   Chen,H.I. and Sudol,M.
  TITLE     The WW domain of Yes-associated protein binds a proline-rich ligand
            that differs from the consensus established for Src homology
            3-binding modules
  JOURNAL   Proc Natl Acad Sci U S A 92 (17), 7819-7823 (1995)
   PUBMED   7644498
REFERENCE   7  (bases 1 to 1338)
  AUTHORS   Sudol,M., Chen,H.I., Bougeret,C., Einbond,A. and Bork,P.
  TITLE     Characterization of a novel protein-binding module--the WW domain
  JOURNAL   FEBS Lett 369 (1), 67-71 (1995)
   PUBMED   7641887
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY159385.1, CX205200.1, AK076948.1 and AI842692.1.
            
            On Apr 12, 2007 this sequence version replaced NM_016757.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY745369.1, AK152822.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY159385.1         1-29
            30-653              CX205200.1         1-624
            654-1315            AK076948.1         586-1247
            1316-1338           AI842692.1         1-23                c
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 35.94 cM"
     gene            1..1338
                     /gene="Wbp1"
                     /note="WW domain binding protein 1"
                     /db_xref="GeneID:22377"
                     /db_xref="MGI:MGI:104710"
     exon            1..259
                     /gene="Wbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..1105
                     /gene="Wbp1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     WBP-1"
                     /codon_start=1
                     /product="WW domain-binding protein 1 isoform 1"
                     /protein_id="NP_058037.2"
                     /db_xref="CCDS:CCDS39529.1"
                     /db_xref="GeneID:22377"
                     /db_xref="MGI:MGI:104710"
                     /translation="MARASSRNSSEEAWGSLQAPQQQQSPAASSLEGAIWRRAGTQTR
                     ALDTILYHPQQSHLLRELCPGVNTQPYLCETGHCCGETGCCTYYYELWWFWLLWTVLI
                     LFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPP
                     AYEDVVHHPGTPPPPYTVGPGYPWTTSSECTRCSSESSCSAHLEGTNVEGVSSQQSAL
                     PHQEGEPRAGLSPVHIPPSCRYRRLTGDSGIELCPCPDSSEGEPLKEARASASQPDLE
                     DHSPCALPPDSVSQVPPMGLASSCGDIP"
     exon            260..364
                     /gene="Wbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            365..467
                     /gene="Wbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            468..644
                     /gene="Wbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            645..1321
                     /gene="Wbp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1300..1305
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Wbp1"
                     /note="hexamer: ATTAAA"
     polyA_site      1320
                     /gene="Wbp1"
                     /note="major polyA site"
ORIGIN      
        1 tgattggctg gactgagcaa ctgtgtcctc tggaggtgct ctccccggcc gggagctccg
       61 gccgcggagt gatggtggca ccggtggcga tgggccgggc agggaccatg gaagtggcgg
      121 cagaggtggc aggggcgggg cagctggcgg tggaggaggc tgtggtcttc aggggtctgt
      181 aggtggaggc atggctcggg ccagcagcag gaacagcagc gaagaggcct gggggtcact
      241 tcaggcgccg caacagcagc agagtccggc agcatcttct cttgagggag caatttggag
      301 acgagctgga acccagactc gcgccctgga taccatcctt tatcatccac agcaatccca
      361 tctgcttcga gagctgtgcc caggagtgaa tacccagccc tacctctgtg agactggtca
      421 ttgctgtggg gagactggct gctgcaccta ctactatgaa ctctggtggt tctggctgct
      481 ttggactgtc ctcatcctct ttagctgctg ttgtgccttc cgccaccgaa gggctaaact
      541 caggctgcaa cagcaacagc ggcagcgtga aatcaacttg ttggcttacc atggggcatg
      601 ccacggggct ggccctgttc caaccggttc actgcttgac cttcgcctcc tcagcgcctt
      661 caaaccccca gcctacgagg atgtggttca ccacccaggc acaccgccac ctccttacac
      721 tgtgggccca ggctaccctt ggactacttc cagtgaatgc acccgctgct cttccgaatc
      781 cagctgctct gcccacttgg aggggacaaa tgtagaaggt gtttcctccc agcagagtgc
      841 tctccctcac caggagggtg agcccagggc aggattgagc ccagttcaca tacccccttc
      901 ctgccgctat cgtcgcctaa ctggtgactc gggtattgag ctctgccctt gtcctgactc
      961 cagtgaaggt gagccactca aggaagcgag ggctagtgcc tcccagccag atctggaaga
     1021 ccattcccct tgtgcactgc ccccagattc tgtgtcccaa gttcctccca tggggctggc
     1081 ttctagttgt ggggacatcc cataagtagt ttcaagaggg aaactgggta ttacttggcc
     1141 accaggattc agccctggtt tcaactgcag tcctccatgt gggaccgtcc ccaccctcct
     1201 agaacacgcc tgaaagggct ggagccctga agaggggcag caccgaggac tgtgctatct
     1261 ttactcactc ccaagacata cacaggagcc tttaatctca ttaaagagac atgaaccagc
     1321 taaaaaaaaa aaaaaaaa
//
