LOCUS       NM_027906               6928 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus von Willebrand factor A domain containing 8 (Vwa8),
            transcript variant 1, mRNA.
ACCESSION   NM_027906 XM_001002205 XM_915363
VERSION     NM_027906.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6928)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6928)
  AUTHORS   Luo,M., Willis,W.T., Coletta,D.K., Langlais,P.R., Mengos,A., Ma,W.,
            Finlayson,J., Wagner,G.R., Shi,C.X. and Mandarino,L.J.
  TITLE     Deletion of the Mitochondrial Protein VWA8 Induces Oxidative Stress
            and an HNF4alpha Compensatory Response in Hepatocytes
  JOURNAL   Biochemistry 58 (49), 4983-4996 (2019)
   PUBMED   31702900
  REMARK    GeneRIF: VWA8 null cells had higher levels of oxidative stress and
            protein degradation; assays of hydrogen peroxide production
            revealed higher levels of production of reactive oxygen species.
REFERENCE   3  (bases 1 to 6928)
  AUTHORS   Grewe,B.S., Richmond,J.E. and Featherstone,D.E.
  TITLE     The spatial and developmental expression of mouse Vwa8 (von
            Willebrand domain-containing protein 8)
  JOURNAL   Gene Expr Patterns 29, 39-46 (2018)
   PUBMED   29660410
  REMARK    GeneRIF: Analyses indicate that the mouse Vwa8 gene produces two
            transcripts; the full-length Vwa8a is highly expressed relative to
            the truncated Vwa8b transcript across all developmental time points
            and tissues analyzed.These data establish the development timeline
            and expression profile for both Vwa8a and Vwa8b.
REFERENCE   4  (bases 1 to 6928)
  AUTHORS   Luo,M., Mengos,A.E., Ma,W., Finlayson,J., Bustos,R.Z., Xiao Zhu,Y.,
            Shi,C.X., Stubblefield,T.M., Willis,W.T. and Mandarino,L.J.
  TITLE     Characterization of the novel protein KIAA0564 (Von Willebrand
            Domain-containing Protein 8)
  JOURNAL   Biochem Biophys Res Commun 487 (3), 545-551 (2017)
   PUBMED   28414126
  REMARK    GeneRIF: The VWA8 protein was targeted exclusively to mitochondria
            in mouse AML12 liver cells, and this was prevented by deletion of
            the targeting sequence.
REFERENCE   5  (bases 1 to 6928)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 6928)
  AUTHORS   Newbury,A.J. and Rosen,G.D.
  TITLE     Genetic, morphometric, and behavioral factors linked to the
            midsagittal area of the corpus callosum
  JOURNAL   Front Genet 3, 91 (2012)
   PUBMED   22666227
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6928)
  AUTHORS   Ghazalpour,A., Doss,S., Zhang,B., Wang,S., Plaisier,C.,
            Castellanos,R., Brozell,A., Schadt,E.E., Drake,T.A., Lusis,A.J. and
            Horvath,S.
  TITLE     Integrating genetic and network analysis to characterize genes
            related to mouse weight
  JOURNAL   PLoS Genet 2 (8), e130 (2006)
   PUBMED   16934000
REFERENCE   8  (bases 1 to 6928)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   9  (bases 1 to 6928)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155167.4, AC124709.3 and AC139758.3.
            
            On or before Apr 19, 2009 this sequence version replaced
            XM_915363.3, XM_001002205.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes a longer protein isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.14889.1,
                                           SRR10223970.17173.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-266               AC155167.4         116742-117007       c
            267-344             AC155167.4         97329-97406         c
            345-475             AC155167.4         57932-58062         c
            476-586             AC155167.4         53906-54016         c
            587-754             AC155167.4         40756-40923         c
            755-919             AC155167.4         32355-32519         c
            920-969             AC155167.4         31542-31591         c
            970-1078            AC155167.4         30894-31002         c
            1079-1183           AC155167.4         28976-29080         c
            1184-1315           AC155167.4         18913-19044         c
            1316-1450           AC155167.4         16767-16901         c
            1451-1528           AC155167.4         16608-16685         c
            1529-1689           AC124709.3         41560-41720
            1690-1803           AC124709.3         43513-43626
            1804-1972           AC124709.3         53724-53892
            1973-2050           AC124709.3         54410-54487
            2051-2166           AC124709.3         68488-68603
            2167-2273           AC124709.3         77931-78037
            2274-2380           AC124709.3         79904-80010
            2381-2452           AC124709.3         85330-85401
            2453-2529           AC124709.3         97449-97525
            2530-2605           AC124709.3         115971-116046
            2606-2741           AC124709.3         117997-118132
            2742-2861           AC124709.3         119853-119972
            2862-3067           AC124709.3         121808-122013
            3068-3219           AC124709.3         124178-124329
            3220-3328           AC124709.3         140437-140545
            3329-3467           AC124709.3         142097-142235
            3468-3667           AC124709.3         145944-146143
            3668-3778           AC124709.3         151615-151725
            3779-3843           AC124709.3         153050-153114
            3844-3969           AC124709.3         153522-153647
            3970-4079           AC124709.3         154996-155105
            4080-4234           AC124709.3         155709-155863
            4235-4430           AC124709.3         157558-157753
            4431-4512           AC124709.3         161560-161641
            4513-4717           AC124709.3         162816-163020
            4718-4826           AC139758.3         176607-176715       c
            4827-4983           AC139758.3         173666-173822       c
            4984-5092           AC139758.3         169575-169683       c
            5093-5218           AC139758.3         152921-153046       c
            5219-5377           AC139758.3         150656-150814       c
            5378-5476           AC139758.3         136277-136375       c
            5477-5715           AC139758.3         135327-135565       c
            5716-6928           AC139758.3         131477-132689       c
FEATURES             Location/Qualifiers
     source          1..6928
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 41.9 cM"
     gene            1..6928
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /note="von Willebrand factor A domain containing 8"
                     /db_xref="GeneID:219189"
                     /db_xref="MGI:MGI:1919008"
     exon            1..266
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..5824
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; von Willebrand factor A domain-containing
                     protein 8"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 8 isoform 1 precursor"
                     /protein_id="NP_082182.1"
                     /db_xref="CCDS:CCDS49550.1"
                     /db_xref="GeneID:219189"
                     /db_xref="MGI:MGI:1919008"
                     /translation="MQSRLLLLGAPGGLGDVASRRVRLLLRQVLRGRPGGDQQRLEVR
                     LLHSGATDSGETVSIGDVSYKLKTPKNPELVPQNYISDSPAQSIVQHLRWLMQKDLLG
                     QDVFLIGPPGPLRRSVAMQYLELTKREVEYIALSRDTTETDLKQRREIRAGTAFYIDQ
                     CAVRAATEGRTLVLEGLEKAERNVLPVLNNLLENREMQLEDGRFLMSAERYDKLLQDH
                     TKEELDAWKIVRVSENFRVIALGLPVPRYSGNPLDPPLRSRFQARDIYFLPFQDQLKL
                     LYSVGANVSAEKISQLLSFATTLCSQESSTLGLPDFPLDSLPEAVQILDSFPMMSIEH
                     ALQWVYPYTLLLGHEGKMAVEGVLKRFELQGSGHSLLPKEIVRVERMTDSHGSYAHVT
                     IRVAGKEVTIKVPAGTRAVNQPCAPDHFIQTVSHKQLLAEMVQSHMVKDICLIGGKGC
                     GKTVIAKNFAALLGYSIEPIMLYQDMTARDLLQQRYTLPNGDTAWRSSPLVSAAREGK
                     LVLLDGIHRVNAGTLAVLQRLIHDRELSLYDGSRLLREDRYLSLKEKLQLTDEQLQNR
                     SIFPIHPSFRIIALAEPPIVGSTTQQWLGPEFLTMFFFHHMKPLVKSEEIQVIKETVP
                     NVPQEALEKLLSVTHKLRETQDPTAQSLAASLSTRQLLRISRRLSKYPSENLHDAITK
                     ACLSRFLPSLAQSALEKNLADAAIETNTEDSLEPELENYKCEVVAGSLKIGAVSVPVH
                     NAHEKMKVPDVLFYDNVQHMVVMEDMLKDFVLGEHLLLVGNQGVGKNKIVDRFLHLLN
                     RPREYIQLHRDTTVQSLTLQPTVKGGLIVYEDSPLVKAVKLGHILVVDEADKAPTNVT
                     CILKTLVENGEMILADGRRIVADAANVDGRENLVAIHPDFRMLALANRPGFPFLGNDF
                     FGTLGDIFSCHAIDNPKPHSELSMLKQYGPDVPEPVLQKLVAAFGELRNLADQGIINY
                     PYSTREVVNIVKHLQKFPTEGLSSVVRNVFDFDSYNNDMREILMNTLHKYGIPIGAKP
                     TNVQLAKEFPLPEKTFMGYWIVGQTGNGMQKVLCPAETNHVDIKGPVLVNMEKYPIEK
                     HEARFLSFTEECTSWKFPLDEVNLICDIAVSHENGEQTLYVAACNPVSLYFMNMTGKN
                     GFFVDFFDIFPRMASGSWRPFVTVAPLGSPLRGQVVLHEEQSNAVLLLDTTGSAIRRL
                     VLPTEEFTSKKSSWWSKEEGETYRMCKEFSHKNWVVFYKQTGNSLTVLDVLEGLAHTI
                     SLPINLRTVFLVAEDKWLLVENETNQKYLLTKPAHIGSEDTGACQLYMLKEELPSTGF
                     GVTQETEFCIPDKVSSDQLSSENLTSAVGQKIASPNRILSDENSHATIVVGFPDLMSP
                     SEVYSWKRSSSLRQPSVTSMTMYTGKRTNATPRHNNCVTLTHTNQVVRILPPGEVPLK
                     DLYPKDVTPPQTAGYIEVTDLQAKKLRYIPVPSAESLSPYTAWISAISDTDALLAEWD
                     KSSVVTVDMGGRVRLWETGLERLQQSLMEWRNMIGQDSDKHVQITIERDSNEDVSDPK
                     HGKEDPDNMPHVGGNTWAGGTGGRDTAGLGGKGGPYRLDAGHPVYQVSEVEKDAVPED
                     VKRAAREMAQKAFQQRLKEIQMSEYDAATYERFSSAVQRQVHALRIILDNLQAKGKER
                     QWLRHQATGELDDAKIIDGLAGEKSIYKRRGDLEPQLGSPQQKPKRLRLVVDVSGSMY
                     RFNGVDRRLERSMEAVCMVMEAFENYEEKFKYDIAGHSGDGYNIKLVPVNQIPKNNKQ
                     RLEILKTMHEHSQFCMSGDHTLEGTEHAIKDITTEEADEYFVIILSDANLSRYGINPA
                     RFAQILTSDPQVNAFAIFIGSLGDQAARLQRTLPAGRSFIAMDTKKIPQILQQIFTST
                     MLSSI"
     exon            267..344
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            345..475
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            476..586
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            587..754
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            755..919
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            920..969
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1078
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1183
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1315
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1450
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1528
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1689
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1803
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1972
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2050
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2166
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2273
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2380
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..2452
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2529
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2530..2605
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2606..2741
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2742..2861
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..3067
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3219
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3220..3328
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3329..3467
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3667
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3668..3778
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3779..3843
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3844..3969
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            3970..4079
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4080..4234
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4235..4430
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4431..4512
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4513..4717
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4718..4826
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4827..4983
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            4984..5092
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            5093..5218
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            5219..5377
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            5378..5476
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            5477..5715
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     exon            5716..6928
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      6177
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /note="major polyA site"
     regulatory      6889..6894
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /note="hexamer: AATAAA"
     polyA_site      6928
                     /gene="Vwa8"
                     /gene_synonym="1300010F03Rik; 4932416F07Rik; Kiaa0564;
                     mKIAA0564"
                     /note="major polyA site"
ORIGIN      
        1 cccgcctccc tgccgcttcc tgtcccgctc gccgatcgcc tcctgcccgg tccagggact
       61 gtgcttgtcc gaagcccctg gaggtcccac gcatgcctcc tgcaccatgc agtcacgcct
      121 cctcctccta ggagccccgg gcggccttgg ggacgtggcc tcccggcgag tgcggctgct
      181 cttgcggcag gtgttgcggg gcaggccggg cggggaccag cagcggctgg aggtcaggct
      241 gctgcactct ggggcgaccg actcaggtga aacggttagt attggagatg tgtcctacaa
      301 gctgaaaact cccaagaatc cagaacttgt cccacagaac tacatttcag actctccagc
      361 tcagtccata gtccagcatc tgagatggct gatgcagaag gatctgctgg ggcaggatgt
      421 ctttctcatc ggacctcctg ggcctctccg gcgctcggtg gctatgcagt acttggagct
      481 gaccaaacga gaggtggaat acatcgccct gtcaagggac accactgaaa ctgacctcaa
      541 acagcgccgg gagatccgag ctggcacagc cttttacatt gaccagtgtg cggttcgggc
      601 tgccacagaa ggcaggacgc tggttttaga aggcttggaa aaggcggaga gaaacgtgct
      661 tccagtactg aacaacttgc tggagaaccg ggagatgcag cttgaagatg ggcgcttcct
      721 catgtctgcg gagcgctatg acaagcttct ccaagatcac actaaagagg agctggacgc
      781 gtggaagatt gtccgagtca gtgagaattt ccgagtgatt gccttgggct tgccagtgcc
      841 caggtactct gggaatccat tagacccccc tctccggtct cgatttcaag ccagagatat
      901 ctattttcta ccctttcagg accaactaaa actattgtat tcagttggag ccaatgtttc
      961 tgctgagaag atttctcagc tcttgtcctt tgcgacaacc ctctgctccc aagaatcctc
     1021 tacgcttggg cttccagact ttcccttaga tagtttgcca gaggcagttc aaatcctgga
     1081 ctcctttccc atgatgtcga ttgaacatgc actccagtgg gtgtatcctt acactctttt
     1141 actcggacac gaggggaaga tggccgtgga gggtgtttta aaacgctttg agctccaagg
     1201 ttctggacat tccctgcttc ctaaggagat tgtaagagtg gagaggatga ctgacagcca
     1261 cggctcctat gcccacgtga caatccgggt cgcaggaaaa gaggtgacca ttaaggtacc
     1321 agcggggacc agagcagtaa accagccttg tgctcctgac catttcattc agactgtcag
     1381 tcacaagcaa ttactggctg agatggtgca gtctcatatg gtgaaggaca tatgcttaat
     1441 tggagggaag ggctgtggga aaacggtcat cgctaagaac tttgctgctc tcctaggata
     1501 cagcatagaa cccatcatgc tttaccagga tatgactgcg cgggacctgc tacagcagcg
     1561 gtacacgctc cccaacggcg acaccgcctg gcgctcctca ccccttgtga gtgctgcccg
     1621 ggaaggcaaa ctggtcctgt tggatggtat ccaccgcgtc aacgctggca cactggctgt
     1681 attgcaaaga ctgatccatg accgggagct cagcctgtat gatggatctc ggctgctgag
     1741 ggaggacagg tacctgagct tgaaggagaa gctacaactg accgatgagc agctacagaa
     1801 caggtccatt tttcctatcc acccttcctt cagaatcatt gcgttggcag agcccccaat
     1861 tgttggaagc acaacacagc agtggctggg accagaattt ttaactatgt tctttttcca
     1921 tcacatgaag cctcttgtga aaagtgaaga aatccaagtg ataaaggaga cggttccaaa
     1981 tgtacctcag gaagcactgg agaaattgct gtcagtcact cacaaactca gggagaccca
     2041 ggatcccaca gcacagtcct tggcagcctc gctttccacc cgtcagctct tacggatctc
     2101 tcgccggctc tcgaagtatc ccagcgaaaa tcttcatgat gccattacca aagcctgtct
     2161 ttccaggttc ttaccaagcc ttgctcagtc tgcactggag aagaatctgg cagatgcggc
     2221 aatagaaaca aacactgagg acagcctgga gccagagctg gagaattaca agtgtgaagt
     2281 agtcgccggg tctctgaaga ttggcgccgt cagtgtgcca gtgcacaatg cccatgagaa
     2341 gatgaaagtg cctgacgttc ttttctacga caatgttcag cacatggtag tgatggaaga
     2401 catgcttaaa gactttgtcc ttggcgaaca cttactattg gttggtaacc agggggtagg
     2461 aaagaacaag attgtggacc gattccttca cctgctcaac agaccccgag aatatataca
     2521 gctgcacagg gacaccacag tgcagtctct gactctccag cccacagtga aaggtggact
     2581 gattgtatat gaagactcac ctctggttaa agcagtaaag ttgggtcata ttctagtagt
     2641 agatgaggca gacaaagccc caacaaatgt cacctgtatt ttgaagactc tggtagaaaa
     2701 cggagaaatg attcttgcgg acggaagacg tattgttgca gatgcagcaa atgtggatgg
     2761 aagagagaac cttgtcgcga tccatcctga cttcaggatg ctggctctgg ccaacaggcc
     2821 tggcttcccc ttcttgggca atgatttctt tggaacttta ggtgacattt ttagctgtca
     2881 tgccattgac aaccccaagc cccactcaga gctttcgatg ctcaaacagt acggcccaga
     2941 cgtgcctgag cccgtcctgc agaagctcgt ggcagccttt ggagagctga ggaacttggc
     3001 tgaccaaggg attatcaact acccttattc caccagagaa gtggtcaaca tcgtcaagca
     3061 cttacagaaa tttcccactg aaggcctctc cagtgtggtt cggaatgtat ttgacttcga
     3121 ttcttacaac aacgacatga gggagatttt gatgaacact ttgcacaaat atgggatccc
     3181 cattggagca aagcctacca acgtgcagct ggcaaaggag tttcctctgc cagagaagac
     3241 attcatgggc tactggatag ttggccagac gggaaatgga atgcagaagg tcttgtgtcc
     3301 agctgaaaca aatcacgttg acataaaggg cccagtactt gtgaacatgg aaaagtaccc
     3361 aatagaaaaa catgaagcga gattcctaag ctttactgaa gagtgtacgt cctggaagtt
     3421 tccattggat gaagtcaatt taatctgtga catcgctgta tcacatgaaa acggagaaca
     3481 gactctgtat gtggctgcgt gcaacccggt ttccttgtac ttcatgaata tgacagggaa
     3541 aaatggcttc tttgtggact tcttcgacat cttcccaagg atggccagtg ggtcctggcg
     3601 accatttgta acagtagccc cactgggaag tcctctgagg ggtcaagttg ttctgcatga
     3661 ggagcagagt aatgccgtcc tcttactcga cactactggc agtgccattc gccgtctcgt
     3721 ccttcccaca gaagagttta catctaagaa gtcttcatgg tggagcaagg aggaaggtga
     3781 aacttataga atgtgtaaag aattctcaca caaaaactgg gtagtattct acaaacaaac
     3841 agggaatagc ttgactgtcc tggatgtctt agaaggacta gctcacacca tctcacttcc
     3901 catcaacctc aggacagttt tcctggtggc ggaggacaaa tggcttcttg tggaaaacga
     3961 aacaaatcag aagtatcttt tgactaagcc tgcacacatt ggttctgagg acactggggc
     4021 ctgtcagttg tatatgttga aagaagagct gcctagcaca ggatttggag tcacacaaga
     4081 aacagagttc tgcatacctg ataaagtgtc aagtgatcag ctgtcatctg aaaacctaac
     4141 ttcagctgtg ggccagaaga tcgcctctcc taaccgtatt ctctcggatg aaaatagcca
     4201 cgctaccata gttgttggct tcccggacct catgtcaccc agtgaagttt attcatggaa
     4261 gaggtcttcg tctttgagac aaccaagtgt taccagcatg acaatgtaca cagggaagcg
     4321 gacaaatgcc accccacggc acaacaactg cgtgactctc acacatacta atcaggtggt
     4381 gaggattctg cccccaggag aagtccctct gaaagacctc tacccaaaag atgttactcc
     4441 cccccagaca gctggctaca tagaggttac tgatctccaa gcaaagaaac tccgttacat
     4501 ccctgtcccc agcgcagagt ctctctcgcc atacaccgca tggatatctg ctatttcaga
     4561 cacagatgct ctgctggctg agtgggacaa gagcagcgtc gtgactgttg atatgggagg
     4621 gcgtgtcagg ctctgggaaa ctggacttga acgtctgcag cagtcgctca tggaatggag
     4681 aaacatgatt ggacaagaca gtgacaaaca tgtgcagata acaatcgaaa gagacagtaa
     4741 tgaagacgtg agtgacccca aacatggcaa ggaggaccca gacaacatgc cccatgtggg
     4801 tggcaatacc tgggctggtg gaacaggggg aagagacacc gcaggtcttg gtggcaaagg
     4861 aggtccttat cgcttggatg caggccaccc agtgtatcaa gtctctgagg tggagaaaga
     4921 tgcagttcct gaggatgtca agagagctgc aagagagatg gcccagaaag catttcagca
     4981 gagactaaag gagatccaga tgagcgagta cgacgccgca acctacgagc ggttttcaag
     5041 tgctgtccag cggcaggtgc atgctctccg catcatcctg gataatctac aggctaaagg
     5101 caaagaaaga cagtggctaa gacaccaagc taccggagaa ctggacgacg ccaagatcat
     5161 tgacgggctg gcgggagaaa agtccatcta caaacgtcgg ggtgacctgg aaccccagct
     5221 gggtagtcca caacagaagc ccaagcgcct gcgcctggtg gtggacgtct ccggcagcat
     5281 gtaccgcttc aacggggtgg atcgccggct agagcgctcg atggaggcag tgtgcatggt
     5341 catggaagcc ttcgagaact acgaggagaa attcaagtac gacatcgctg gacactcggg
     5401 agatggctac aacattaagc tcgttccagt taaccaaatc cccaagaaca ataagcagag
     5461 actagaaatt ctgaagacga tgcacgagca ctctcagttc tgcatgagtg gggaccacac
     5521 acttgaggga acggaacacg ccatcaagga cattaccaca gaagaagctg atgagtactt
     5581 tgtcatcatc ttaagtgatg caaatctgtc ccgatacgga ataaacccgg cccgctttgc
     5641 ccagatcctg acaagcgatc ctcaagtaaa cgcctttgcc atttttatcg gctctttggg
     5701 ggatcaggca gccaggcttc agagaactct gccagctggc cggtccttca tcgctatgga
     5761 taccaagaag atccctcaga tcttacaaca gatcttcacc tccaccatgc tgtccagtat
     5821 ctaagacgca cacttcacca tcccacgatt ggacgcaaat aggagcagag agaattacga
     5881 agaggcagcg accaagccga cctgtgccat gtccagcatc gagcagacct acgagtagaa
     5941 gtgtactctg gatgggttga aggtctgcaa aggaaacggg ttgacctgca tttcttaaaa
     6001 ggtcagggtt gaaggataca ggctcaggaa ctgtaaggct aggcctagtt ctaaacccaa
     6061 aggataaaaa tcacccactg ttgccttaat atgtcatctg ctgccagatg ccatacgaag
     6121 ccttttaata aaagcccata gtttgaccct gagggacaag tctgcaaacc ctcccaacat
     6181 gttcctgtct gtggttattt ctgctttctc tgcagtgtgt attgcccagc aaataacaat
     6241 tttacagcag ttaaccttaa ctggaaagta tttggacagc agtacttgat aaggcattgg
     6301 attctctcag taatcctgtt ctctggacag aaaggaacca aacggtccct agggtgcttg
     6361 ctgtcccacc tgacttctat tcacgctgct acccgagctg aaagataaag atatcctgcc
     6421 tcaggttccc tgtgtcagcc cttttcagtt ccccagagtt ccactgtgga gtacagtata
     6481 cttcgccatc caaattacag tgctgaacgt agtgagtgct catgtctgac aaattaccca
     6541 aaatccaaaa cactgcgttt gactgggtgt cgcctggaga cttgctttga tttaactaaa
     6601 gaaacgcata tttttctctt gtctttcaaa gtctttaaaa tcacacaatc caacagaacc
     6661 gtcgctcgag cacgtgatga aacgctgctc tgacatgaat tcagtgctga ggccccatta
     6721 tgtgcgtgtt tacctagtgt aagctggaaa actcaccttg tgttatgtta ccctagccag
     6781 gtacagtgtc atcgtacagg cccgtaaatt catttcattt gattgtagga cagagaaaaa
     6841 aggttcccca tctcttctaa caccccatct cctgctcatc cgctgtcaaa taaaagcagt
     6901 cgcttcccag tatggtgtca ccacccaa
//
