LOCUS       NM_001384105            4771 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus von Willebrand factor A domain containing 5B2
            (Vwa5b2), transcript variant 4, mRNA.
ACCESSION   NM_001384105 XM_030249162
VERSION     NM_001384105.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4771)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087898.19.
            
            On May 28, 2020 this sequence version replaced XM_030249162.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.748168.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-746               AC087898.19        114216-114961       c
            747-895             AC087898.19        113814-113962       c
            896-1066            AC087898.19        113564-113734       c
            1067-1286           AC087898.19        110715-110934       c
            1287-1444           AC087898.19        110390-110547       c
            1445-1576           AC087898.19        109663-109794       c
            1577-1701           AC087898.19        109294-109418       c
            1702-1857           AC087898.19        108784-108939       c
            1858-1968           AC087898.19        107984-108094       c
            1969-2177           AC087898.19        107683-107891       c
            2178-2289           AC087898.19        107490-107601       c
            2290-2475           AC087898.19        106841-107026       c
            2476-2647           AC087898.19        104315-104486       c
            2648-2961           AC087898.19        103914-104227       c
            2962-3151           AC087898.19        103377-103566       c
            3152-3505           AC087898.19        102925-103278       c
            3506-3643           AC087898.19        101129-101266       c
            3644-3724           AC087898.19        100968-101048       c
            3725-3930           AC087898.19        100663-100868       c
            3931-4771           AC087898.19        99737-100577        c
FEATURES             Location/Qualifiers
     source          1..4771
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 12.47 cM"
     gene            1..4771
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /note="von Willebrand factor A domain containing 5B2"
                     /db_xref="GeneID:328643"
                     /db_xref="MGI:MGI:2681859"
     exon            1..746
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            747..895
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     CDS             757..4479
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /note="isoform 4 is encoded by transcript variant 4; von
                     Willebrand factor A domain-containing protein 5B2"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 5B2 isoform 4"
                     /protein_id="NP_001371034.1"
                     /db_xref="GeneID:328643"
                     /db_xref="MGI:MGI:2681859"
                     /translation="MPGLYCPTSWTPLPLTDSCVRAYAKGPCLSLRARLTYHNPQPQP
                     VEGVFVYPLAEAEVVSGFEAEAAGRRVSFQLHSRRRSQAACCRALGPGLGTSTPRRCA
                     QGHLVLNLAQARSTLVLPTGLVAAAGTMTVTLCSSRELPSRPDGVMHVALPTVFTPLA
                     QPNLPGSPRSPGLCDDSPTSCFGVGSPEEERPTWEQPTATPDVFSGPARCPAPYTFSF
                     EMLVTGPCLLAGLESPSHALRADALPHASSAATIRVTLAEGHQCDRALEILLHPSEPH
                     QPHLMLETGSLSSAEYEAQVRARHDFQRLQQRDSGGERQVWFLQRRFHKDILLNPVLV
                     LNFCPDLSSKPGHLNAATRELLFLLDGSGAGHKDAIVLAVKSLPAQTLVNLAIFGTLV
                     QPLFPESRPCSDDTVQLICESIETLQTVNGPPDMLAVLDWALGQPQHRAYPRQMFLIT
                     AASPTAATTHQALEFMRWHRGAARCFSFALAPACRQLLHDLSVLSRGQAYFLRPGERL
                     QPKLVQALRKALEPALSDISVDWFVPDAVEALLTPREIPALYPGDQLLGYCSLFRVDG
                     FRSHALGGQEPGWQSLAGSVFPSPEEVLSATSPGTEPTHTTEPLGTGTVSAELSSPWA
                     VGDSEQSMEALTDPVMDPGPNPSSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGST
                     CSSESPGSQGPGSPSGSRPLDPPSQQGCRSLAWVEPAGSRSCPLPVPPPSPFKVGAMS
                     AEVLGRRQRAALAGRSLSSPSGRANPVPGRARHPSLDAIPDGLGPEPGQQLGQGLDDS
                     GNLLSPAPLDWDMLMEPSFLFKPVPSSAESAPPAECLPPQAPRCHVVIRALCGEQPMC
                     WEVGVGLEELWGPGDGSQPESLPMREAAWDQALHRLTAASVVQDNEQLALRGRAETRA
                     EQGRVRRSWLRAIQTSKVSSAPSCFTCPVAVDATTREVLPGALQVWSSDPAELSGMSA
                     SQDQLAAAPLSTAVHSKGAWDLDLNDNSKSALGEPISPTGDHHGLPHQPPASSRLSLG
                     RHRRLCSSNKGQTHENSNDGSNHDYLPLVRLQEAPGSFRLDEPFCAAVCIPQERLCRA
                     SPFAAHRASLSPTSASSPWAFLSPGIGQGDSATASCSQSPSSGSEGPGQVDSGRGSDT
                     EASEGMERQDSSDLRGRTWATAVALAWLEHRCAAAFGEWELTASKADCWLRAQHLPDG
                     LDLTALKAAARGLFLLLRHWDQNLQLHLLCYSPSNV"
     exon            896..1066
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1286
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1444
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1576
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1701
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1857
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1968
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2177
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2289
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2475
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2647
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            2648..2961
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            2962..3151
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            3152..3505
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            3506..3643
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            3644..3724
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            3725..3930
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     exon            3931..4771
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4750..4755
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /note="hexamer: AATAAA"
     polyA_site      4771
                     /gene="Vwa5b2"
                     /gene_synonym="EG328644; Gm1738; Gm931"
                     /note="major polyA site"
ORIGIN      
        1 acaggatctc agtggtagtt ccgaggtgga tcgcgcaggt gcaggaacaa ggggcagtct
       61 ggacatcaga ggaagcatca cccactcttg tctggtcgcg acgccccaca actccaccaa
      121 gaagtgacgg tgaggcttgg gctgcccaaa gggagggggc gatcccaaga cccaccctgt
      181 agcatcccct gtggctacct agtctcaggc cagcctgggc ggggagagcc gctctagatc
      241 agatgacatg gactcccgct gccgcgacac ctctgcacat ctgacttccc gagacgcatt
      301 ttcccgtccc tttctagttc ttcctactgc aacctttcaa gacggtctac agcctctctc
      361 agtactccag tcacgaaagg caaggagaga taaagactgc agccttttca gctcccgacc
      421 tcaccctgtc cctggggacc cttgtgagct aggggcgcct agggcaatgc tggcccttta
      481 aacctttgct ttccacccag agtatcttcc atctctccag aagcaccact tccgacagct
      541 ggcaaccgtg gagagccagg aggcaggggg caggtacggg ggcggtggtg aggccccgag
      601 aaggtgcagg aacagctgtg ggcaccaccc cccaagcccc cggctcgcaa cccgcagcgg
      661 gactggagga cgcctggact ggagggttaa ccattaaccc tccattcccc cattgcggag
      721 agctgttccc tgctcctgct acccagggtg ggcaccatgc ctggcctgta ctgccccacc
      781 agctggacgc cgctgccgct caccgactcc tgcgtccggg cctatgccaa gggaccctgc
      841 ctcagcctgc gtgcccggct tacctaccac aacccacagc cccagccggt ggaaggcgtg
      901 ttcgtgtacc ctctggctga ggcggaggtg gtatctggct tcgaggccga ggcggccgga
      961 cggcgcgtct ccttccagtt gcatagccgg cgccgatcac aggccgcctg ctgtcgcgct
     1021 ctgggcccgg gactagggac ctctacaccc cgccgctgcg cacagggtca tcttgtcttg
     1081 aatctggccc aagcccggtc cacactggtg ttgcccactg gccttgtggc tgcagctggt
     1141 accatgacag tgaccctgtg cagcagccgg gagttgccct ccaggcctga tggggtgatg
     1201 catgtggccc tgcccactgt gttcacccca ctggcccagc caaacctgcc agggtccccc
     1261 aggtctccgg ggctctgtga cgacagcccc accagctgct tcggggtagg cagccctgag
     1321 gaggaaaggc cgacctggga gcaaccaact gccactccgg acgtgttctc aggccctgcc
     1381 cgctgtcctg ctccgtatac cttctctttc gagatgctag tgaccggacc atgtctgttg
     1441 gcaggcctgg agagcccctc tcatgctctg cgtgcagatg ccctccctca tgccagctct
     1501 gcagcaacta tccgtgtcac cctggcagag ggccaccagt gtgatcgggc cttggagatc
     1561 ctcttgcacc ccagtgagcc ccatcagcca cacttgatgc tggagactgg cagcttgagt
     1621 tcagcagaat atgaggccca agtgagggcc cgccatgact tccagaggtt gcagcaaaga
     1681 gacagtggtg gggaacggca ggtctggttc ctgcagcgac ggttccataa ggacatcttg
     1741 ctgaaccctg tgctggtgct gaacttctgc ccagacctga gctccaagcc tggacacctg
     1801 aatgcagcta cccgggagct cctcttcctg ttagatggca gtggtgcagg acacaaggat
     1861 gccattgttt tggctgtaaa atccctccca gctcagactc tagtcaacct agccatattt
     1921 gggacattgg tacagccact cttcccagag agccggcctt gcagtgatga cactgtgcag
     1981 ctgatctgcg agagcatcga gactctccag actgtgaatg gtccccctga tatgctggct
     2041 gtattggatt gggccttagg gcagccccag cacagggcct accctcgaca gatgttcctg
     2101 atcactgctg cctcgccaac ggctgccacc actcaccaag ccctggagtt tatgaggtgg
     2161 cacagagggg cagccaggtg cttctccttt gcattggcac ctgcctgccg ccagctgctc
     2221 catgacttgt ctgtcctcag cagaggacag gcttacttcc tgaggcccgg ggagagactt
     2281 cagcccaagc tggtacaggc tctgcggaag gcactggaac ctgctttgag tgacatctct
     2341 gtggactggt ttgtgcctga tgctgtggag gcactgctga caccccggga gatcccagct
     2401 ctctaccctg gggaccagct gcttggctac tgctcgcttt tcagggtgga tggcttccgg
     2461 tcccatgctc tagggggaca agagcctggt tggcagagct tggccggttc agtcttccca
     2521 tctccagagg aggtgttatc cgccaccagc cctggcactg agcctacgca caccacagag
     2581 cccctgggaa caggcactgt gtcagcagag ctgtcgagcc catgggctgt aggcgactca
     2641 gagcagagta tggaagctct gacagaccca gtcatggatc ctggacctaa tccctcatct
     2701 gacacagcta tatggcggcg catcttccag tcctcataca tccgggagca gtatgtgctt
     2761 acccactgct ctgccagccc tgagccaggc ccaggctcca cctgcagtag cgagtcccca
     2821 ggttcccaag gccctggctc ccccagtggt agccgtcccc tggatccccc ttctcagcag
     2881 ggctgccgaa gcctggcctg ggtagaacct gcaggctccc gctcctgccc cctgcctgta
     2941 cccccaccat ctccattcaa ggtgggagcc atgagcgctg aggtgctggg ccgtcggcaa
     3001 agagcagctc tggctggtcg aagtctctca tctccctcag gccgggcaaa cccagtcccc
     3061 ggaagagccc ggcacccctc tctagatgca ataccagatg gattaggccc tgagccagga
     3121 caacagctgg gtcagggcct cgatgattca ggaaacctgc tctccccagc ccccttggac
     3181 tgggatatgt tgatggaacc atctttctta ttcaagcctg tgccgtccag tgcggaatca
     3241 gctcctccag cagaatgtct gcctcctcag gctccacgtt gccacgtggt gatccgggcc
     3301 ctgtgtgggg aacagccaat gtgctgggag gtgggtgttg ggctggaaga actctggggt
     3361 cctggggatg gctcccagcc tgaatcactt ccgatgagag aagctgcgtg ggatcaggca
     3421 ctccaccggc tgacagcagc ctctgtggtc caggacaatg aacagctggc tctccgtgga
     3481 agagctgaaa ccagggctga gcagggcaga gtcagaaggt cctggctcag agccattcag
     3541 acaagcaagg tcagctctgc cccatcctgt tttacctgcc ctgttgctgt agatgctacc
     3601 actagggagg tattgcctgg agccctgcag gtgtggagtt cagatccagc tgagctctca
     3661 ggcatgtctg cctctcaaga ccagctagct gccgctcctc tgtccacagc agtccactct
     3721 aaaggtgcct gggacctgga cctaaatgac aactccaagt cagcattggg ggagcccata
     3781 tctcctactg gagatcatca tggcttgccc caccagcctc cagcctcttc caggctcagc
     3841 ctgggtcgtc atcgaagact ctgcagctcc aataagggcc agactcatga gaacagcaat
     3901 gacggcagca accatgacta cctgcctctg gtacgactgc aagaggcacc aggctccttc
     3961 cgcctggatg aacccttctg tgctgctgtg tgcattcctc aagaacgcct gtgtcgagcc
     4021 tcgccctttg ccgcacaccg tgccagcctc agccccacct cagcatcatc tccttgggca
     4081 tttctgagcc ctggtattgg ccaaggtgac agtgccacag cctcctgcag ccagtccccc
     4141 agctcaggtt ctgagggtcc aggccaggta gacagtggga ggggctcaga tactgaggcc
     4201 tcagaaggaa tggaaaggca ggacagctct gatcttcgtg ggcgcacttg ggccacagct
     4261 gtggccctgg cgtggctgga acaccgctgt gcagctgcct ttggcgagtg ggaactgaca
     4321 gcttccaaag ctgattgctg gctgagagcc caacacctgc cagacggact tgatctgact
     4381 gctcttaaag ctgctgcccg ggggctcttt ctgttactgc gacactggga ccagaatctg
     4441 cagctacact tgctgtgtta cagcccttcg aatgtgtaag gctgcttgca gctctggcta
     4501 gcgaccccca acacagtcac tgccacccag ggccagtctc ttggtgctgg gaaagaataa
     4561 gttggtgtct gccgtcctcc attgcttcac atacacacac acacacaccc ctcccaacat
     4621 tcttgtcacc acagaaagtg cctgcctgtg ctctcttctc tctcctccca ctccataccc
     4681 cctcctatgt gctctgagct ctctatagga taatggaaga ggagagagct acggtcccaa
     4741 atcctatgca ataaagtgcc tcttaagact g
//
