LOCUS       NM_029401               3857 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus von Willebrand factor A domain containing 5B1
            (Vwa5b1), mRNA.
ACCESSION   NM_029401 XM_144060 XM_914601
VERSION     NM_029401.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3857)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3857)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC132477.1.
            
            On or before Sep 7, 2008 this sequence version replaced
            XM_914601.3, XM_144060.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC132477.1, AK016425.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3857
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 70.43 cM"
     gene            1..3857
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /note="von Willebrand factor A domain containing 5B1"
                     /db_xref="GeneID:75718"
                     /db_xref="MGI:MGI:1922968"
     exon            1..88
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            89..250
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..3759
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /note="von Willebrand factor A domain-containing protein
                     5B1"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 5B1 precursor"
                     /protein_id="NP_083677.1"
                     /db_xref="CCDS:CCDS51336.1"
                     /db_xref="GeneID:75718"
                     /db_xref="MGI:MGI:1922968"
                     /translation="MPGLLNCLTGAALPLMESDVTSYVSGYALGLTASLTYGNLEAQP
                     FQGLFVYPIDEYSTVVGFEAVIADRVVTIQLRDKAKLDRSHLDIQPATVTGNFPEEES
                     PIAPGKVTLDEDLERVLFVVNLGTIAPMENVTVFISTSSELPTLPSGAVRVLLPAICA
                     PTVPPSCTHRFGSSSPQPQGKDPHCFGTQTKDSYNRLCLATLLDTKVTNPMEYEFKFQ
                     LEIRGPCLLAGVESPTHEIRADAAPSAHSAKSIIITLAKKHTFDRPVEILLHPSEPHM
                     PHVLVEKGDMTLGEYDQHLKGKADFIRGTKKDNSAERKTEVIRKRLHKDIPHHSVIML
                     NFCPDLQSVQPNPRKAHGEFIFLIDRSNSMSKTNIQCIKEAMLVALKSLMPACFFNII
                     GFGSTFKAVFASSRIYNEENLTMACDCIQRMQADMGGTNMLSPLKWVLRQPLRRGHPR
                     LLFLITDGSVNNTGKVLELVRNHASSTRCYSFGIGPTVCYRLVKGLASVSKGSAEFLM
                     EGERLQPKMVKSLKKAMAPVLSDVTVEWVFPETTEALISPVSTSSLFPGERLMGYGIV
                     CDASLYISNSRSDKRRKYGMLHTQESSSSVFYPSQDEGLSPGSGNCAKNVNQGQTKDA
                     HPCNGDSPTHHGLDVSRRRRAYSTNQISSHKTCPRATTASDPTGTARRYPLRKAKVQD
                     LASESDWESQKWQTDLQTLLNEGHNLSQGPKLHGPGARRPSLLPQGCQLMRFFDQKPQ
                     AWGPVRELDCGASRTSAPNSQSSEDLAIEPAHCPSTFERETSLDLEPMAESEEQANPC
                     RTATPSPVVGKALVKGLCANQRMQWEVSFELEPPALKRGDTQNADMWSETFHHLAARA
                     IIREFEHLAEREDEIELGSNRRYQVNAVHTSKACSVISKYTAFVPVDINKRQYLPTVV
                     KYPNSGAMLSFRNLTRQWGGSSAGLGRPQSMLREHSSAAGDSKFQTLALQDSPTSTFN
                     KTPSPGHEKQTTAEGPPQNLSASAPSSMKATETLFGSKLNLNKSRLLTRATKGFLSKS
                     LPKASEATPGSQSSDYIPLVSLQLASGAFLLNEAFCTTIQIPMEKLKWTSPFSCLRMS
                     LVTRRQDLKTQSPQDCTSLSSSPPSCDGISLKSEESSDQESNAMLEHMGKLWATVVAL
                     AWLEHSSANYIIEWELVAAKASSWVEKQKVPEGRTLSTLKNTARQLFVLLRHWDEKLE
                     FNMLCYNPNYV"
     exon            251..394
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            395..650
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            651..796
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            797..928
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1053
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1230
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1341
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1544
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1659
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1845
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..2017
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2208
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2410
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2731
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2732..2869
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2870..2995
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3070
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3071..3140
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3258
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3259..3857
                     /gene="Vwa5b1"
                     /gene_synonym="4931403E03Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgccagtct gtggtttggg cttgaacctc cctaaagaaa tgaagggatt tctagggata
       61 acaagaggaa ccgaacccca aaactgagac tctgagcaga gaagtcccag aatgcctggc
      121 ctgctgaact gcctcacagg ggcagccctg cctctcatgg aatccgatgt cacctcctat
      181 gtcagtggct atgccctggg cctgacagcc tccctcacct acggcaacct ggaggcccag
      241 ccctttcaag gtctcttcgt gtatccaata gacgagtata gcacagtggt tggctttgaa
      301 gcagtcattg ctgaccgtgt tgtgaccata cagctcagag acaaagccaa gctggacaga
      361 agccacttgg atatccaacc cgccactgtc acagggaact ttccggaaga ggagagtccc
      421 atcgcaccag gaaaggtgac cttggatgag gatctggagc gggttctgtt cgtggtcaac
      481 ctggggacca ttgcccccat ggagaatgtc accgtcttca tcagcacctc ctccgaactc
      541 cccacactgc ccagcggggc tgtgagggtt cttctgccgg ccatctgcgc cccgaccgtg
      601 cctccatcct gtacccacag gtttggctcc tccagcccac agccacaagg caaagaccca
      661 cactgcttcg gcacccagac caaggactcc tataacaggc tgtgtctggc cactctcctg
      721 gacacaaagg tgaccaaccc aatggaatat gaattcaaat ttcagctgga aatccgtggg
      781 ccctgtctgc tcgcaggggt ggagagtccc actcatgaaa tccgagcaga cgcagcccca
      841 tcggcacact ccgccaagag catcatcatc acgttggcca aaaaacatac ctttgaccgg
      901 ccagtggaga ttcttctcca ccctagcgag cctcacatgc cacacgtcct ggtggagaaa
      961 ggggacatga ccctggggga atatgaccag cacttgaagg gaaaagcaga tttcattcgg
     1021 gggacaaaga aggacaacag cgcggagcgg aagacagaag tcatccggaa gcgtctccac
     1081 aaagacattc cccaccactc agtcatcatg ctcaacttct gtcctgacct ccagtctgtg
     1141 cagcccaacc cgaggaaagc ccacggggag tttatcttcc tcattgatag gagtaacagc
     1201 atgagcaaga ccaacatcca gtgcatcaag gaggccatgc tggtggccct caagagcctc
     1261 atgccagcgt gcttcttcaa catcattggt tttggatcca catttaaggc agtctttgct
     1321 tccagtcgga tctacaatga ggagaacttg accatggcat gtgactgcat ccagagaatg
     1381 caggctgata tgggaggcac caacatgctc tcccccctca agtgggtcct gcggcagcca
     1441 ctgcgccggg gtcacccacg gctcctcttc ctgatcacgg atgggtccgt gaacaacaca
     1501 gggaaggttc tggagctggt acggaatcac gcctcttcta ccaggtgcta tagctttgga
     1561 attggaccca cggtctgcta ccgactggtc aaagggctgg catctgtatc caagggcagc
     1621 gcagagttcc tgatggaggg ggaacggctg caaccaaaga tggtcaaatc cttgaagaag
     1681 gccatggcgc cagtgctgag tgacgtgact gtggagtggg tctttcccga gaccacggag
     1741 gccctgatct ctcctgtcag caccagctcc cttttccctg gggaacggct gatgggatat
     1801 ggcattgtgt gtgatgcctc cttgtacatt tccaattcca gatctgacaa aaggcgaaag
     1861 tatggcatgc tgcacactca ggagtccagc agctccgtct tctacccctc acaggacgag
     1921 ggactcagcc caggcagtgg aaactgtgcc aagaacgtca accaggggca gaccaaagat
     1981 gcccatccat gcaatggaga ctcccccacc catcacggtc tggatgtctc ccggcggcgg
     2041 agagcataca gcactaacca gatctccagc cacaagactt gcccaagggc taccacagcc
     2101 agcgacccca ccgggactgc caggagatac ccactgcgaa aagccaaggt gcaagacctt
     2161 gccagtgaga gcgactggga gagccagaag tggcagactg atctgcagac cctacttaac
     2221 gaaggccata acctgagcca gggccccaaa cttcatggcc caggagcccg caggccttcc
     2281 ctactgcctc aaggctgcca gctcatgcgc ttctttgacc agaagcccca ggcctggggc
     2341 cctgtgagag agctggattg tggtgccagc cggacgtctg cccctaacag ccaaagctct
     2401 gaagatctgg ccatagagcc agcccattgt ccttcaacct ttgaacggga gacatcctta
     2461 gacttggagc ccatggctga gtccgaggag caagccaatc cctgcaggac tgccactcca
     2521 agccctgtgg tgggcaaggc tttggtcaaa ggcctgtgcg ccaaccaacg catgcagtgg
     2581 gaagtgagct tcgagctgga gcctccagcc ctgaagaggg gggacacaca gaacgctgac
     2641 atgtggagtg agactttcca ccacctggcg gcccgcgcca tcatccgaga attcgagcat
     2701 ctggcagagc gcgaggacga gatcgagctg gggtccaatc gccgatacca ggtgaacgcc
     2761 gtgcacacca gcaaggcctg cagcgtgatc agcaaataca cggcctttgt gcctgtggac
     2821 ataaacaaga ggcagtacct gcccacggtc gtcaagtacc ccaactctgg tgccatgctc
     2881 agcttccgga acctgactcg acagtggggg ggctcttcgg ctggcctggg aaggccccag
     2941 tctatgctca gagaacactc ctcagccgca ggagacagca aattccagac tctagcccta
     3001 caagacagcc ctacttcaac cttcaataaa accccatccc ccggccatga gaagcaaacc
     3061 acggcagaag gtccccctca aaacctgtcc gccagcgctc catcctccat gaaggccact
     3121 gagactctct ttggatctaa gttgaatctc aacaaatcca ggctgctgac ccgagctacc
     3181 aaaggctttc tcagcaaatc gttgcccaag gcttcagagg caaccccagg cagccagagc
     3241 tctgactaca taccactggt gtctctgcag ctggcctcgg gagccttttt gctcaatgaa
     3301 gccttctgca cgaccatcca aatccccatg gagaaactca agtggacctc acccttctcc
     3361 tgcctccgaa tgtccctcgt cacccgccga caggatctga agacccagag tccacaggac
     3421 tgcaccagtc tctcctcttc acccccatcc tgtgacggca tctccctaaa gtctgaagag
     3481 agctcagacc aggagtccaa tgcaatgctg gagcacatgg gaaagctgtg ggccacggtg
     3541 gtggcgctgg cgtggctgga acacagctca gctaactaca tcattgagtg ggagctggtg
     3601 gctgccaagg ccagctcctg ggtggagaag cagaaagttc ctgagggccg caccttgagc
     3661 actctcaaga acactgctcg ccaactcttt gtgcttctgc gacactggga tgagaaatta
     3721 gagttcaata tgctctgtta caaccccaat tatgtgtaag ggatggggag ggtgatgatg
     3781 ggctgtttga gttgctaggg gaactttttg aaagccgtag ccaatagggt attgctagaa
     3841 agtgccttgg actggca
//
