LOCUS       NM_001370828            4552 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus von Willebrand factor A domain containing 3B (Vwa3b),
            transcript variant 1, mRNA.
ACCESSION   NM_001370828 XM_006496378
VERSION     NM_001370828.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Lu Y, Oura S, Matsumura T, Oji A, Sakurai N, Fujihara Y, Shimada K,
            Miyata H, Tobita T, Noda T, Castaneda JM, Kiyozumi D, Zhang Q,
            Larasati T, Young SAM, Kodani M, Huddleston CA, Robertson MJ,
            Coarfa C, Isotani A, Aitken RJ, Okabe M, Matzuk MM, Garcia TX and
            Ikawa M.
  TITLE     CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched
            genes dispensable for male fertility in micedagger
  JOURNAL   Biol Reprod 101 (2), 501-511 (2019)
   PUBMED   31201419
REFERENCE   2  (bases 1 to 4552)
  AUTHORS   Hong S, Choi I, Woo JM, Oh J, Kim T, Choi E, Kim TW, Jung YK, Kim
            DH, Sun CH, Yi GS, Eddy EM and Cho C.
  TITLE     Identification and integrative analysis of 28 novel genes
            specifically expressed and developmentally regulated in murine
            spermatogenic cells
  JOURNAL   J Biol Chem 280 (9), 7685-7693 (2005)
   PUBMED   15613475
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122872.3, AC137516.3 and AC133096.3.
            
            On Jun 5, 2019 this sequence version replaced XM_006496378.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AC122872.3         38059-38174         c
            117-348             AC122872.3         31619-31850         c
            349-443             AC122872.3         25098-25192         c
            444-694             AC122872.3         22279-22529         c
            695-857             AC122872.3         15608-15770         c
            858-1027            AC122872.3         6988-7157           c
            1028-1143           AC122872.3         3938-4053           c
            1144-1269           AC137516.3         74507-74632
            1270-1460           AC137516.3         89910-90100
            1461-1615           AC137516.3         98270-98424
            1616-1754           AC137516.3         103735-103873
            1755-1886           AC137516.3         104932-105063
            1887-1985           AC137516.3         113225-113323
            1986-2162           AC137516.3         118158-118334
            2163-2293           AC137516.3         124709-124839
            2294-2451           AC137516.3         127004-127161
            2452-2565           AC137516.3         130365-130478
            2566-2653           AC137516.3         132003-132090
            2654-2810           AC137516.3         132185-132341
            2811-2929           AC137516.3         146607-146725
            2930-2980           AC137516.3         153774-153824
            2981-3182           AC137516.3         154920-155121
            3183-3294           AC133096.3         173801-173912       c
            3295-3419           AC133096.3         172127-172251       c
            3420-3557           AC133096.3         170281-170418       c
            3558-3658           AC133096.3         168530-168630       c
            3659-3835           AC133096.3         161042-161218       c
            3836-4552           AC133096.3         160139-160855       c
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 15.46 cM"
     gene            1..4552
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /note="von Willebrand factor A domain containing 3B"
                     /db_xref="GeneID:70853"
                     /db_xref="MGI:MGI:1918103"
     exon            1..116
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            117..348
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..3914
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="von Willebrand factor A domain-containing
                     protein 3B isoform 1"
                     /protein_id="NP_001357757.1"
                     /db_xref="GeneID:70853"
                     /db_xref="MGI:MGI:1918103"
                     /translation="MAEQSLLSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSL
                     RRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSG
                     SRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPV
                     KWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVG
                     DVPQEFQKLLLTGVLEIPYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTECE
                     EFSAFSTEGVDGSMTWNSRKLKGRLPPGAGVREDVFLIWREMEEACRILAQVRSLVDK
                     APQSDVSPADCKSRPAESKENAEDTWESQKWLQKYGLKAQKLTFYDVLAHCSFRHADG
                     VVDIKAKPENESVQTSADTNKKTIHAKYCSRFIHIPWKDGSLVHVNITKEKYKWYRER
                     IHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMKSRLNLVKDKIIQFIQE
                     QLRYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAF
                     ADEETQVIYLLTDGRPDQPPEMVMDHVKLFQNIPICAISFSYNDEVANEFLKELAALT
                     GGEFRAYNFGCKDPIQDTQDEDLNLLLQEMEQGHSDLEKMQELYMESLVVDWWYNADK
                     DTDSKHQKEILSMVSTPEERANSQPDADSLASSPPNVSTGSWKFLEEKTQKKKILHAE
                     STKTSLLRSHISNFKSSSNKDSSNSSSRSHTSALSNREMSVLLTNKCLDDKLSESASG
                     NGSQVSGHTSSDTSSKTWLQTHGLVAKKLTIADALAGAMVPHSSTYVPILNKNVVSKV
                     FDEVFPLAHVCNNSNKMVLINPHGINLNIYKQNVEQAIKSYEKCLNKIVWQALSEEEK
                     EKLDAIKPIQYLENKDVLNKALERLNWPISLKELSVLENEILVGKMYIQQALELQETS
                     RKNYQSKTLQEQQKLQGYPTKKIKSRKLDPLKGQKVIARCEENGFYFPGVVKKCVSSS
                     HALVDFRYGDTKVVPISFIMPVGGAMPCPQLQVGDYVFAKIMTSKGFDFYVPAIVIAL
                     PNHNVASEKFYTVLKCNNRREFCPRSALIKISQNKYALSCSMIHSSLVEKNGAGEEVD
                     GSNSSNIWTVTEEATGNLKQPRQENLRKKRKKRTKRLPLQELMCSDFDGSSRSTREGF
                     PHVASDAANSALATLPPGAALP"
     exon            349..443
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            444..694
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            695..857
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            858..1027
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1143
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1269
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1460
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1615
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1754
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1886
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..1985
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2162
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2293
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2451
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2565
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2653
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..2810
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2811..2929
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2930..2980
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..3182
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3294
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3295..3419
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3420..3557
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3558..3658
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3659..3835
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
     exon            3836..4552
                     /gene="Vwa3b"
                     /gene_synonym="4921511C04Rik; A230074B11Rik; Gm555"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacagaaact ggactcccgc aactctgtgc ccgaggcggg gacccttcgc cagcatcagg
       61 gggagtcaca gccttgtcca gcagtgggat gctggccgcg cccacctcct gctctggtgg
      121 ctccttgtga ctcagggtct tgatttagag atgggggaat caggatcacg tttccatatt
      181 gtctcagagt agtaggcgca gaggcaggag cgactgaaca agaccaggac tgcatggcag
      241 agcagagtct cctttcatcg gagagatggc ttcagttgca tgggctaaag agcaagaagc
      301 tgaccttgaa gcagatctta tcacagatcg gattcccaca gagtgaagat tatgtgactt
      361 ctttgaggag actcgtggct tctcggtatg ctgatggcct gttcccacag atctacacag
      421 cagaagatgg cagactatac aacctgacag caaagacaga gctgatctgc cagtttgtgg
      481 attacttaac acaagccgtg gagagctaca agcagcggat ggactggctc accagcggaa
      541 gccggcagat ttttggtgtt atcttggaac agagagtcac catagtgctg gacttcggtg
      601 acgttctgat ggaggagctc aatctgtgtc gggatgcttt gaaaatggtc ctccaggagc
      661 aggtggctct catcaccagg ttcaacatga tatgggtttc cgcagagccg gtgaaatggc
      721 aggagtacgc catccttgtg accgagcact ccatagctgc tgctatcagc tggattgaga
      781 aaatgacttt tgagccaaag cctgtgagag aggttagcgg cctagatgct ctgctggaag
      841 ctgggaaaga caaaaccatc gaagccatct actactttgt ggtgggggat gttcctcagg
      901 agttccagaa gcttctacta acgggggttc tggagatccc atatccagtc tgcacagtgt
      961 ccttcaatgc cagaggagaa gaaaccatag ctttcctaaa agatctgagc actaagaccc
     1021 acagcagatt ccatgccttt gctgagagaa cagagtgtga ggaattctct gcattttcca
     1081 cggagggcgt tgacggctcc atgacttgga attcacggaa actgaaaggg agactccctc
     1141 caggggctgg cgtcagagag gatgtgtttc tcatctggag agaaatggaa gaagcctgca
     1201 gaatactggc tcaggtccgg agcctggtgg acaaggctcc tcagtcggat gtgtccccag
     1261 ctgactgcaa gtcaaggcct gctgagagta aggaaaatgc agaagacacc tgggagtccc
     1321 agaagtggct ccagaagtac ggcttgaagg ctcagaagct gaccttttac gatgtcctcg
     1381 cccactgctc cttccgccat gctgatggag ttgttgatat aaaagccaaa ccagaaaacg
     1441 aatctgtgca gaccagtgcg gacaccaata agaagacaat ccatgccaaa tactgcagca
     1501 gattcatcca catcccctgg aaggatggga gcttggtcca cgtcaacatc accaaggaga
     1561 aatacaagtg gtacagggag agaatccaca cagccctggc catgatacaa aggaggatta
     1621 agtggctaca aaatgggagt cacatcctct ttggcaaagc gcgtggagag tgcatctatg
     1681 tcctcatcga cacgtcctgc tcaatgaaga gcagactaaa cctggtcaag gacaagatca
     1741 ttcagttcat acaggaacag ctcagataca agagtaagtt caattttgtg acgtttgatg
     1801 gtcaggcaat tgcttggcgg gaaaaacttg ctgaagtcaa tgaagataat ttgaaacagg
     1861 ctcagtcgtg gattagaggc atcaaggttg gaagttccac aaataccctg aatgccctga
     1921 aaattgcttt tgctgatgaa gaaacacaag taatctacct tctgacagat gggagaccgg
     1981 accagccacc agaaatggtg atggaccacg tcaaactctt tcagaacatc cccatctgtg
     2041 ccatctcctt cagttacaac gatgaggttg cgaacgagtt cttgaaggag cttgctgcct
     2101 tgaccggagg cgagttccga gcttataact ttggctgcaa ggatcccatt caggatactc
     2161 aggatgaaga tctgaacctt ttgcttcagg aaatggagca gggtcacagc gacctggaga
     2221 agatgcagga gctctacatg gagtccttag tcgttgactg gtggtacaac gcagacaagg
     2281 acacggatag caaacaccaa aaggaaatct tgtccatggt ttcaactcca gaagagcgtg
     2341 caaactccca acccgacgcc gattcactgg cttcttcacc cccaaatgtg tctacaggat
     2401 catggaagtt tttggaggaa aagacacaga aaaagaaaat cctccatgca gaatcaacca
     2461 aaacgagcct cctcagaagc cacatctcca acttcaagag cagcagcaac aaagacagct
     2521 ccaactccag ctccaggagc cacacctcag ctctcagcaa cagagaaatg agcgtcctgc
     2581 tgacgaacaa gtgtctagat gacaaattgt cagaaagcgc cagtggaaat ggaagccaag
     2641 ttagtggcca cacctcttca gacacgtcct ccaaaacctg gctccaaact catggcctgg
     2701 tggccaagaa actcaccatc gcagatgcct tggctggagc catggtaccc cacagctcca
     2761 cctatgtccc catcctgaat aagaatgttg tctccaaggt ctttgatgag gtgttccctc
     2821 tggcacatgt gtgcaacaac agcaataaga tggtattaat taacccccat ggaatcaacc
     2881 tcaatatcta caagcaaaat gtggaacagg ccatcaaatc ctatgaaaaa tgcttaaata
     2941 aaattgtctg gcaagctctg tctgaagagg aaaaagagaa gttggatgca atcaagccca
     3001 tacagtactt ggaaaacaag gatgtcttga acaaggccct ggagcggctg aattggccca
     3061 tttcattgaa agagctctcg gtgctggaaa acgaaatctt ggttgggaaa atgtacatcc
     3121 agcaagccct ggagctccag gagacttcca ggaagaacta ccagagcaag acactgcagg
     3181 agcagcagaa attgcaaggg tatccaacga agaaaatcaa atcaagaaaa ctagaccctc
     3241 tcaaaggcca gaaggtcatt gccagatgtg aggaaaatgg cttctatttt ccaggggttg
     3301 tgaagaaatg tgtgagttcc tcccacgcct tggtcgactt caggtacgga gacaccaaag
     3361 tcgtgcccat ctccttcatc atgcctgttg ggggcgccat gccctgtcca caacttcagg
     3421 ttggggatta cgtgtttgcc aaaatcatga caagcaaagg atttgacttc tacgtccccg
     3481 ccattgttat agcacttcca aatcacaacg tggcttcaga gaagttctac acagttttga
     3541 agtgtaacaa ccgcagagaa ttttgccctc ggagtgctct cattaagatc agccaaaaca
     3601 agtatgccct gtcttgctca atgatacact catccctggt tgagaagaac ggagcagggg
     3661 aggaagtaga tggaagtaat tcttccaaca tctggactgt gactgaagaa gccactggga
     3721 atttgaaaca gccgagacaa gagaacctca gaaaaaagag aaagaaacgc accaagaggc
     3781 tccctctcca agagctgatg tgttcagatt ttgatggttc ctcccgcagc accagagaag
     3841 gttttccaca cgtggcctcg gacgccgcca actccgccct cgccacactg ccaccaggag
     3901 cagccctgcc ctgacagagt ccagccaccc acagcgaaag gggctgagga cccaccgctg
     3961 agggacccta aagaacccca gtggcagcta actttaagca agccactgtc ccccagggct
     4021 gctcagaccc cagcctctgg accctgtgga gcaagcctct cttctgaggt aaggcttgcc
     4081 ttgtttctac ccagtacctt ccctgtggat gagagccagc tcccccgtcc cccagcctgg
     4141 cgctcctact gtctgagttt agggatcttt ctgagcattc tttgcccccg cctcccctct
     4201 caccacaaaa ctgttgtcag tctttggata cacacttagc agccctagcc tggcaggcgg
     4261 ctgtcagaaa cagaaagccc agggctcttt gaggactcca cgcagttagg ctccacacct
     4321 gcggggttgc tttaaattgg ttcttccttg tggattaagg atttttgcca cacagtgtag
     4381 aggctgagat tactacttgg tccgtggctt gtctgagagc tgtaaggccg agtgttctct
     4441 atgttactat ttcctgaaca tttttagtga gcccttccta attgattttg tctgtagtct
     4501 gttgtaggta cctctgagtg cagaacccga ataaactctc ttacattgga aa
//
