LOCUS       NM_025418               1343 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus vesicle (multivesicular body) trafficking 1 (Vta1),
            mRNA.
ACCESSION   NM_025418 NM_026766
VERSION     NM_025418.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Hermosilla Aguayo,V., Martin,P., Tian,N., Zheng,J., Aho,R., Losa,M.
            and Selleri,L.
  TITLE     ESCRT-dependent control of craniofacial morphogenesis with
            concomitant perturbation of NOTCH signaling
  JOURNAL   Dev Biol 503, 25-42 (2023)
   PUBMED   37573008
REFERENCE   2  (bases 1 to 1343)
  AUTHORS   Boone,M., Mobasheri,A., Fenton,R.A., van Balkom,B.W., Wismans,R.,
            van der Zee,C.E. and Deen,P.M.
  TITLE     The lysosomal trafficking regulator interacting protein-5 localizes
            mainly in epithelial cells
  JOURNAL   J Mol Histol 41 (1), 61-74 (2010)
   PUBMED   20358264
  REMARK    GeneRIF: LIP5 protein expression in a mouse tissue panel and
            various rodent and human tissues were studied.[LIP5]
REFERENCE   3  (bases 1 to 1343)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   4  (bases 1 to 1343)
  AUTHORS   van Balkom,B.W., Boone,M., Hendriks,G., Kamsteeg,E.J., Robben,J.H.,
            Stronks,H.C., van der Voorde,A., van Herp,F., van der Sluijs,P. and
            Deen,P.M.
  TITLE     LIP5 interacts with aquaporin 2 and facilitates its lysosomal
            degradation
  JOURNAL   J Am Soc Nephrol 20 (5), 990-1001 (2009)
   PUBMED   19357255
REFERENCE   5  (bases 1 to 1343)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   6  (bases 1 to 1343)
  AUTHORS   Fujita,H., Umezuki,Y., Imamura,K., Ishikawa,D., Uchimura,S.,
            Nara,A., Yoshimori,T., Hayashizaki,Y., Kawai,J., Ishidoh,K.,
            Tanaka,Y. and Himeno,M.
  TITLE     Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact
            with and regulate the function of an AAA-ATPase SKD1/Vps4B
  JOURNAL   J Cell Sci 117 (Pt 14), 2997-3009 (2004)
   PUBMED   15173323
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX212626.1, AK002611.1 and BP770041.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_025418.4.
            
            On Jul 15, 2005 this sequence version replaced NM_025418.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004323.1, AK002611.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 CX212626.1         1-2
            3-1323              AK002611.1         2-1322
            1324-1343           BP770041.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 5.5 cM"
     gene            1..1343
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /note="vesicle (multivesicular body) trafficking 1"
                     /db_xref="GeneID:66201"
                     /db_xref="MGI:MGI:1913451"
     exon            1..140
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..958
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /note="SKD1-binding protein 1; lysosomal trafficking
                     regulator interacting protein-5; Vps20-associated 1
                     homolog"
                     /codon_start=1
                     /product="vacuolar protein sorting-associated protein VTA1
                     homolog"
                     /protein_id="NP_079694.2"
                     /db_xref="CCDS:CCDS23705.1"
                     /db_xref="GeneID:66201"
                     /db_xref="MGI:MGI:1913451"
                     /translation="MAALAPLPPLPAQFKSIQHHLRTAQEHDKRDPVVAYYCRLYAMQ
                     TGMKIDSKTPECRKFLSKLMDQLEALKKQLGDNEAVTQEIVGCAHLENYALKMFLYAD
                     NEDRAGRFHKNMIKSFYTASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGE
                     TPQAGPVGIEEENDVEENEDVGATSLPTQPPQPSSSSAYDPSNLAPGSYSGIQIPPGA
                     HAPANTPAEVPHSTGVTSNAVQPSPQTVPAAPAVDPDLYTASQGDIRLTPEDFARAQK
                     YCKYAGSALQYEDVGTAVQNLQKALRLLTTGRE"
     exon            141..235
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            236..363
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            364..439
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            440..548
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            549..725
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            726..812
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     exon            813..1325
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1304..1309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vta1"
                     /gene_synonym="1110001D18Rik; 1110059P08Rik; LIP5; SBP1"
                     /note="putative"
ORIGIN      
        1 gtaggaagta gcgcttccgg gagtggagat ggccgcgctg gcccctctgc cgccgctgcc
       61 cgcgcagttt aagagcatac agcaccattt gagaacggcg caggagcatg acaagcggga
      121 ccccgtggtg gcctactact gtcgtttata tgctatgcaa actggaatga agattgatag
      181 taaaactcct gagtgtcgta aatttttatc aaagctaatg gatcagttag aagctcttaa
      241 aaaacagttg ggggataatg aagctgttac tcaagaaata gttggttgtg cccatttgga
      301 aaattatgct ttgaaaatgt tcttgtatgc agacaatgaa gatcgagctg gacgatttca
      361 caaaaacatg atcaagtcct tctacactgc cagcctttta atagatgtca tcacagtgtt
      421 tggtgaactc acagatgaaa atgtgaaaca tagaaagtat gcaaggtgga aggcaacata
      481 tattcataac tgcttaaaga atggggagac tcctcaagca ggccctgttg gaatagagga
      541 agagaatgat gttgaagaaa atgaagatgt tggcgcaacc tctctgccca ctcagccacc
      601 tcagccatca tcatcttcag catacgaccc aagcaacttg gcaccaggca gctacagtgg
      661 catacagatt cctccaggtg cacatgctcc agctaatacc cctgcagaag tgccacacag
      721 cacaggtgta acgagtaatg ccgtccagcc tagtccacag actgtcccag ctgctccagc
      781 tgttgatcct gacctgtaca cagcttccca gggggatatc cgcctgaccc cggaggactt
      841 cgctagagct cagaagtact gcaagtatgc tggcagtgcc ctgcagtatg aagatgtggg
      901 caccgctgtg cagaacctcc agaaggccct caggctgctg accacaggca gggagtgaag
      961 cctctgttca cggaagccag tgttttccgc atagagaact aacagtccgt tacactttcc
     1021 tcagccttca ggagcagggg actacagaag gcctcagttc cccgaggaag acaatgactc
     1081 ctgtgtggtt cagaagcatt taccagctgc ctcagccagt tgtcattgag tgtgtagagc
     1141 tgatgctagc atcgaacccg ctgtgaaatg tccctgtaga aaatcatgtt gggtataata
     1201 tgctttctta atttatacac actaaaggaa gtttttgaaa gatctgtaat atttggacaa
     1261 acaaaccata ttatgttgct ttaatattct aaattaaact tttaataaag attaccagaa
     1321 tagtcaaaaa aaaaaaaaaa aaa
//
