LOCUS       NM_198627               1381 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus V-set and transmembrane domain containing 2-like
            (Vstm2l), mRNA.
ACCESSION   NM_198627 XM_203867
VERSION     NM_198627.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Zhang,Q., Huang,R., Ye,Y., Guo,X., Lu,J., Zhu,F., Gong,X.,
            Zhang,Q., Yan,J., Luo,L., Zhuang,S., Chen,Y., Zhao,X., Evans,S.M.,
            Jiang,C., Liang,X. and Sun,Y.
  TITLE     Temporal requirements for ISL1 in sympathetic neuron proliferation,
            differentiation, and diversification
  JOURNAL   Cell Death Dis 9 (2), 247 (2018)
   PUBMED   29445148
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  AUTHORS   Rossini,L., Hashimoto,Y., Suzuki,H., Kurita,M., Gianfriddo,M.,
            Scali,C., Roncarati,R., Franceschini,D., Pollio,G., Trabalzini,L.,
            Terstappen,G.C., Matsuoka,M. and Caricasole,A.
  TITLE     VSTM2L is a novel secreted antagonist of the neuroprotective
            peptide Humanin
  JOURNAL   FASEB J 25 (6), 1983-2000 (2011)
   PUBMED   21393573
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BF323097.1, BQ746346.1 and BC058538.1.
            
            On Nov 28, 2007 this sequence version replaced NM_198627.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058538.1, CA323464.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-386               BF323097.1         1-386
            387-885             BQ746346.1         104-602
            886-1381            BC058538.1         571-1066
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.48 cM"
     gene            1..1381
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /note="V-set and transmembrane domain containing 2-like"
                     /db_xref="GeneID:277432"
                     /db_xref="MGI:MGI:2685537"
     exon            1..279
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..767
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /note="V-set and transmembrane domain-containing protein
                     2-like protein"
                     /codon_start=1
                     /product="V-set and transmembrane domain-containing
                     protein 2-like protein precursor"
                     /protein_id="NP_941029.2"
                     /db_xref="CCDS:CCDS50784.1"
                     /db_xref="GeneID:277432"
                     /db_xref="MGI:MGI:2685537"
                     /translation="MGAPLAAALGALHYLALFLQLGGATRPAGHAPWDNHVSGHALFT
                     ETPHDMTARTGEDVEMACSFRGSGSPSYSLEIQWWYLRSHRDWTDKQTWASNQLKASQ
                     QEDSGKDATKISVVKVVGSNISHKLRLSRVKPTDEGTYECRVIDFSDGKARHHKVKAY
                     LRVQPGENSVLQLPDAPPAAPAPPPKPGRELRKRSLPEACSL"
     exon            280..449
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /inference="alignment:Splign:2.1.0"
     exon            450..500
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /inference="alignment:Splign:2.1.0"
     exon            501..1363
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1344..1349
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /note="hexamer: AATAAA"
     polyA_site      1363
                     /gene="Vstm2l"
                     /gene_synonym="Gm691"
                     /note="major polyA site"
ORIGIN      
        1 cggcgggctg ggcgtgcgct cgctgcctgc agccggggcc gggccggggc cagcaggaga
       61 gggcggcggc ggcgccgggc agggtacggc gggcgcgggc tttgcgggct gcggagcccc
      121 gatgtgaggc ggcggcgccc ccggccggag cgcgcagcat gggggccccg ctggccgcgg
      181 cgctgggcgc cctccactac ctggcacttt tcctgcaact cggcggcgcc acgcgacccg
      241 caggccatgc gccctgggac aaccacgtct ccggacacgc actcttcaca gagacacccc
      301 atgacatgac ggcacggaca ggcgaggatg tagagatggc ctgctccttc cgaggcagtg
      361 gttccccatc atactcactg gagattcagt ggtggtacct gcgcagccac cgggactgga
      421 ctgacaagca gacgtgggcc tccaaccagc tcaaagcttc ccagcaggag gactcgggga
      481 aggacgccac caaaataagt gtggtcaagg tggtgggcag caacatctcc cacaagcttc
      541 ggctgtcccg ggtgaagccc acggacgaag gcacctacga gtgccgcgtg atcgacttca
      601 gcgacggcaa ggcccggcat cacaaggtca aagcatacct gcgggtgcag cccggggaga
      661 actcggtgct gcagctgcct gatgcgcccc ccgccgcgcc ggcgccgccg cccaagccgg
      721 gccgggagct gcgcaagcgc tctctgcccg aggcctgcag cctgtagccc gcccgccccg
      781 catgcagtcc tcccggccct gcggcgacgg cggcagagga gtcccgcgtg tgctttgctt
      841 gcttatcccc ctcccggctc cgcctcgtgc accccgtcct cgcggccagc cccctggtga
      901 ggagccgggc cggggcccaa cgctcctgtt cctcatcatt ctacctggaa ccggctccgg
      961 aaccccgagg gaggcggagc cccaccagcc ccacgcggga ggctgccccg ccaggcagag
     1021 ttagcaccag caggctcgct cagggccccc cgaggctctc cccgagcccc cctctgccgg
     1081 caaccccccc ccacgcccag ccccttctcg ggcctgtgaa gtccacccaa gggaccccct
     1141 ccgcccatcc catccctatt cctgatcagg ggacacccac cctggtggtt tgtaaatatt
     1201 tctattgggc ccaccccgcc ccggaactgg ctcaaacctc tggccaccct cggtgatgga
     1261 ggggaggtgg gaggcccagg gctttgccta ggggtgagcg ggccctgtgt atatgaccca
     1321 acctgtgagt accagccaac tccaataaag cggtttaaac caaaaaaaaa aaaaaaaaaa
     1381 a
//
