LOCUS       NM_001033776            3028 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus vertebrae development associated (Vrtn), transcript
            variant 3, mRNA.
ACCESSION   NM_001033776 XM_484161
VERSION     NM_001033776.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3028)
  AUTHORS   Duan,Y., Zhang,H., Zhang,Z., Gao,J., Yang,J., Wu,Z., Fan,Y.,
            Xing,Y., Li,L., Xiao,S., Hou,Y., Ren,J. and Huang,L.
  TITLE     VRTN is Required for the Development of Thoracic Vertebrae in
            Mammals
  JOURNAL   Int J Biol Sci 14 (6), 667-681 (2018)
   PUBMED   29904281
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159641.2.
            
            On Dec 15, 2009 this sequence version replaced NM_001033776.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 3 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC103771.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AC159641.2         103736-103784       c
            50-3028             AC159641.2         95225-98203         c
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.32 cM"
     gene            1..3028
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /note="vertebrae development associated"
                     /db_xref="GeneID:432677"
                     /db_xref="MGI:MGI:3588197"
     exon            1..49
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            50..3028
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..2273
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /note="vertebrae development homolog (pig)"
                     /codon_start=1
                     /product="vertnin"
                     /protein_id="NP_001028948.1"
                     /db_xref="CCDS:CCDS26048.1"
                     /db_xref="GeneID:432677"
                     /db_xref="MGI:MGI:3588197"
                     /translation="MTSRDQLVQQVLRDLQEAVESEGLEGLIGAALEAKQVLSSFTLP
                     ICQKGGPGAQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEATSLLLWGHTGLSL
                     ELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTNLSFATLEAIFDAD
                     VKATCFPTSFSNVWHLYALASILECNIYSIYPMRNIKIRPYFNRVIMPRCSTHVTSML
                     HIMWAGQPLTSHLFRHQYFAPVVGLEEVEADCTASLNPVPPNLGPLLPPAKTLELLNR
                     EPGLSYSHLCDRISITKSTFYRWRRQTQEHRQKVATRFSAKHFLQDSFHRGGFVPLQQ
                     FLQRFPEISRSTYYAWKHELLGSGANSALGPATPSREALAVPEVERPPGKKAAEEVGC
                     SSLAAAMLSPPSMILMQRAKSFLEYCISLNKLVPYRCFKCRFPGISRSTYYNWRRKAL
                     RRTPSFKLSQAAFETAESLQPTDVGKETPFSLKREAGEEETGKAGSGAPLTSRGLISP
                     KMPLSRWQRRLRRAARKQVLNGHLPFCRFRLRYPSLLPSTFWVWKSLSRRSPGMQIPS
                     LSQRRQKPQGRQKPEGRQKPEEQQKPEGRQKPEGRQKPVEPQAMEADQNVPAMVVPPA
                     ETLPVATSPEDVPGGPSREGNIIQEAAMTQSQPHSGSLPSQTLAEAPGGSDGQVLVMD
                     MLTTTRFKAQAKLFLQKRFQSKTFPSYKEFQALFPLTARSTYYMWKRALYEGLTLIDG
                     "
     regulatory      2598..2603
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /note="hexamer: AATATA"
     polyA_site      2621
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /note="major polyA site"
     regulatory      3002..3007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3028
                     /gene="Vrtn"
                     /gene_synonym="7420416P09Rik"
ORIGIN      
        1 ctggaagtgt gttgcatccg acgctgtgtt ggacactgga ggaattcagg atgacgtctc
       61 gggatcagct ggtgcagcag gtgctgcgcg acctgcagga ggcagtggag tccgagggct
      121 tagagggtct catcggtgct gccctggagg ccaagcaggt cctatcttcc ttcacccttc
      181 ccatctgcca gaagggcggc cctggcgctc aggtgctgga ggtggactca gtggccttga
      241 gtctgtaccc ggaggatgct cctcggaaca tgctgccctt ggtgtgcaag ggtgagggga
      301 gcctgttgtt tgaagcgacc agcctgttgt tgtgggggca cacgggtctc agcctggagc
      361 tgcgagcccg cactgtggtg gagatgctgc tgcacaggca ctattatctg cagggcatga
      421 tcgactccaa ggtgatgctg caggctgtgc gctactcctt gtgctctgag gagtcccctg
      481 agatgaccaa cttatctttt gccacactgg aggccatctt tgatgctgat gtaaaggcta
      541 cgtgcttccc aacgagcttc tccaatgtgt ggcacttgta tgccctcgcc tccatccttg
      601 aatgcaacat ctactccatc taccccatgc gcaacatcaa gatccgaccc tattttaacc
      661 gtgttatcat gcctcgctgc tccacccacg tgacctccat gctgcacatc atgtgggctg
      721 gtcagcccct cactagccac ctcttccgtc accagtattt tgcccctgtt gttgggctgg
      781 aggaggtgga ggctgactgt actgctagcc tgaaccccgt tcctccaaac ctgggtcctc
      841 tgctaccacc cgctaaaacc ctggagctgc tcaaccgtga acctggcctc agctactccc
      901 acctctgtga ccgcatcagc atcaccaaga gcaccttcta ccgctggcgg cggcagaccc
      961 aagagcaccg tcaaaaggta gccacccgct tctctgccaa gcacttcctg caggacagtt
     1021 tccaccgtgg gggctttgtg ccattgcagc agttcctgca gagattccct gagatctccc
     1081 gttctaccta ctatgcttgg aagcatgagt tgctgggctc tggtgccaac tcggccctgg
     1141 gcccggccac tccatccagg gaggcactgg ctgtgccgga ggtggagagg ccaccgggga
     1201 aaaaggctgc tgaggaggtg gggtgctcct cactggcagc agcgatgttg agccctccta
     1261 gtatgatctt aatgcagcgt gccaagtctt tcttggagta ttgcatctct ctgaacaaac
     1321 tggtaccata tcgctgcttc aaatgcaggt tccctggcat ctcgaggtct acctactaca
     1381 actggaggcg gaaagccctc agaaggaccc ccagtttcaa gttgtcccaa gcagcttttg
     1441 aaactgctga gtctctccag ccaacagatg ttgggaaaga gacccccttc tctttgaaga
     1501 gagaagcggg agaggaggag acaggaaaag caggaagtgg ggctcctctg acttcccggg
     1561 ggctcatatc cccaaagatg cccttatctc gttggcagag acgactacgc agggctgccc
     1621 gcaagcaggt gctaaatggg cacctaccct tctgtcgctt ccgcctccgc tatcctagtc
     1681 tgttaccttc cactttttgg gtatggaaaa gtctttcccg gagatcgccc gggatgcaga
     1741 ttccctcttt gagccagagg aggcagaagc ctcagggacg gcagaagccc gagggacggc
     1801 agaagcccga ggaacagcag aagcccgagg gacggcagaa gcccgaggga cggcagaagc
     1861 cagttgaacc acaggctatg gaagctgatc agaatgtacc ggctatggtg gttcctccag
     1921 cggagacact gccagtggct acttctccag aagatgtccc aggagggcct tccagagagg
     1981 gaaacatcat tcaagaggca gctatgaccc agagccaacc ccatagtgga tcgttgccaa
     2041 gccagactct ggcggaggca cccgggggca gtgatgggca ggtgctggtg atggacatgc
     2101 ttaccaccac gaggttcaag gcccaggcca agctgttcct gcagaagcgg ttccagtcta
     2161 agactttccc ctcctacaag gagttccagg cgctcttccc cctcactgcc cgctccacct
     2221 actacatgtg gaagcgggcg ctctatgaag gtctcacact gattgatggc tgatgggagg
     2281 ggaagaaggg gagccgagct gcctcctgac taggatgtcc tttgctctgc cttttgtaac
     2341 gtcttgatgg aggggtggga atcagccgct cgctctgaca aaagctacag gagggccagt
     2401 tgtctctttg gttgttggct gggtcatagg tttttgttgt gtttcatttt gctttttcca
     2461 ttaatttggg ttggcaggac cccctccgcc cctcgtcagt gttaaagctc tgtcatgatt
     2521 gtgacatggc tgctttcagc ttttcctggg cccacaagga aagtatcaca gcgtgaccat
     2581 tatttcctgt cagaataaat atatgtgcct tttcttttta agggttgtat cttttttttc
     2641 cccccctcaa agatgtcttc caaaggaata tggggactga gcctgaggca gctgtgtggc
     2701 tgcttcctca aaccctcggt ggagaaggac tgagcttcac agaacacacg acagtgatct
     2761 ctaagccagg gaaggcccct aggcactgga gaccccaaag agagcttcct gcttcctctg
     2821 ctgggggctg ggggggatct cttcaggtca ggcgtctgcc agcctggctg ctcttgggga
     2881 cctgctgagc cgcctcagac gccaaggcac attttgggca aggagctaca aggttacaag
     2941 gctggtgggg aattgatttt tttttttcat tgtctagcca cacagttgga aacccaaaga
     3001 aaataaagtg aaattttgtc ctcacaca
//
